(Z)-6-[(2S,4S,5R)-2-(2-Chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl]hex-4-enoic acid (BioDeep_00000177280)

   

human metabolite blood metabolite


代谢物信息卡片


(Z)-6-[(2S,4S,5R)-2-(2-Chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl]hex-4-enoic acid

化学式: C22H23ClO5 (402.1234)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: OC(=O)CCC=CCC1COC(OC1C1=CC=CC=C1O)C1=CC=CC=C1Cl
InChI: InChI=1S/C22H23ClO5/c23-18-11-6-4-9-16(18)22-27-14-15(8-2-1-3-13-20(25)26)21(28-22)17-10-5-7-12-19(17)24/h1-2,4-7,9-12,15,21-22,24H,3,8,13-14H2,(H,25,26)

描述信息

同义名列表

5 个代谢物同义名

(Z)-6-[(2S,4S,5R)-2-(2-Chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl]hex-4-enoic acid; (Z)-6-[(2S,4S,5R)-2-(2-Chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl]hex-4-enoate; 6-[2-(2-chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl]hex-4-enoic acid; 6-[2-(2-Chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl]hex-4-enoate; 6-(2-(2-Chlorophenyl-4-hydroxyphenyl)-1,3-dioxan-5-yl)hexenoic acid



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

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PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

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BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Ralf A Benndorf, Edzard Schwedhelm, Anke Gnann, Raihana Taheri, Ghainsom Kom, Michael Didié, Anna Steenpass, Süleyman Ergün, Rainer H Böger. Isoprostanes inhibit vascular endothelial growth factor-induced endothelial cell migration, tube formation, and cardiac vessel sprouting in vitro, as well as angiogenesis in vivo via activation of the thromboxane A(2) receptor: a potential link between oxidative stress and impaired angiogenesis. Circulation research. 2008 Oct; 103(9):1037-46. doi: 10.1161/circresaha.108.184036. [PMID: 18802021]
  • Z Benyó, C Görlach, M Wahl. Role of nitric oxide and thromboxane in the maintenance of cerebrovascular tone. Kidney international. Supplement. 1998 Sep; 67(?):S218-20. doi: 10.1046/j.1523-1755.1998.06753.x. [PMID: 9736296]
  • S M Hutchinson, T G Hammond, R Coleman, A A Horton. Effects of eicosanoids on parameters in isolated rat hepatocytes and isolated rat hepatocyte couplets: protective effects of eicosanoid receptor antagonists. Journal of lipid mediators and cell signalling. 1997 Mar; 15(3):249-54. doi: 10.1016/s0929-7855(96)00560-3. [PMID: 9041475]
  • E H Horn, E Hardy, J Cooper, S Heptinstall, P C Rubin. Platelet reactivity in vitro in relation to thromboxane in healthy pregnancy. Thrombosis and haemostasis. 1996 Feb; 75(2):346-51. doi: 10.1055/s-0038-1650272. [PMID: 8815588]
  • H Arakawa, J Lötvall, A Lindén, I Kawikova, C G Löfdahl, B E Skoogh. Role of eicosanoids in airflow obstruction and airway plasma exudation induced by trimellitic anhydride-conjugate in guinea-pigs 3 and 8 weeks after sensitization. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 1994 Jun; 24(6):582-9. doi: 10.1111/j.1365-2222.1994.tb00956.x. [PMID: 7922778]
  • H Arakawa, J Lötvall, I Kawikova, C G Löfdahl, B E Skoogh. Leukotriene D4- and prostaglandin F2 alpha-induced airflow obstruction and airway plasma exudation in guinea-pig: role of thromboxane and its receptor. British journal of pharmacology. 1993 Sep; 110(1):127-32. doi: 10.1111/j.1476-5381.1993.tb13781.x. [PMID: 8220872]
  • J Lötvall, W Elwood, K Tokuyama, T Sakamoto, P J Barnes, K F Chung. A thromboxane mimetic, U-46619, produces plasma exudation in airways of the guinea pig. Journal of applied physiology (Bethesda, Md. : 1985). 1992 Jun; 72(6):2415-9. doi: 10.1152/jappl.1992.72.6.2415. [PMID: 1385805]
  • C S Lau, F Khan, M McLaren, A Bancroft, M Walker, J J Belch. The effects of thromboxane receptor blockade on platelet aggregation and digital skin blood flow in patients with secondary Raynaud's syndrome. Rheumatology international. 1991; 11(4-5):163-8. doi: 10.1007/bf00332555. [PMID: 1838424]