Cerebrocrast (BioDeep_00000177163)
human metabolite blood metabolite
代谢物信息卡片
化学式: C26H35F2NO7 (511.2381464)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 66.67%
分子结构信息
SMILES: CCCOCCOC(=O)C1=C(C)NC(C)=C(C1C1=CC=CC=C1OC(F)F)C(=O)OCCOCCC
InChI: InChI=1S/C26H35F2NO7/c1-5-11-32-13-15-34-24(30)21-17(3)29-18(4)22(25(31)35-16-14-33-12-6-2)23(21)19-9-7-8-10-20(19)36-26(27)28/h7-10,23,26,29H,5-6,11-16H2,1-4H3
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Elina Leonova, Jelizaveta Sokolovska, Jean-Luc Boucher, Sergejs Isajevs, Evita Rostoka, Larisa Baumane, Tatjana Sjakste, Nikolajs Sjakste. New 1,4-Dihydropyridines Down-regulate Nitric Oxide in Animals with Streptozotocin-induced Diabetes Mellitus and Protect Deoxyribonucleic Acid against Peroxynitrite Action.
Basic & clinical pharmacology & toxicology.
2016 Jul; 119(1):19-31. doi:
10.1111/bcpt.12542. [PMID: 26663724] - Tomislava Lovaković, Marija Poljak-Blazi, Gunars Duburs, Ana Cipak, Marina Cindrić, Brigita Vigante, Egils Bisenieks, Morana Jaganjac, Lidija Mrakovcić, Azra Dedić, Neven Zarković. Growth modulation of human cells in vitro by mild oxidative stress and 1,4-dihydropyridine derivative antioxidants.
Collegium antropologicum.
2011 Mar; 35(1):137-41. doi:
". [PMID: 21661362] - Janina Briede, Mara Stivrina, Dzintra Stoldere, Brigita Vigante, Gunars Duburs. Effect of cerebrocrast on body and organ weights, food and water intake, and urine output of normal rats.
Cell biochemistry and function.
2008 Dec; 26(8):908-15. doi:
10.1002/cbf.1525. [PMID: 19039818] - Janina Briede, Mara Stivrina, Brigita Vigante, Dzintra Stoldere, Gunars Duburs. Acute effect of antidiabetic 1,4-dihydropyridine compound cerebrocrast on cardiac function and glucose metabolism in the isolated, perfused normal rat heart.
Cell biochemistry and function.
2008 Mar; 26(2):238-45. doi:
10.1002/cbf.1442. [PMID: 17990288] - J Briede, M Stivrina, Dz Stoldere, B Vigante, G Duburs. Effect of cerebrocrast, a new long-acting compound on blood glucose and insulin levels in rats when administered before and after STZ-induced diabetes mellitus.
Cell biochemistry and function.
2007 Nov; 25(6):673-80. doi:
10.1002/cbf.1372. [PMID: 16986170] - Maria A S Fernandes, Amália S Jurado, Romeu A Videira, Maria S Santos, António J M Moreno, Astrida Velena, Gunars Duburs, Catarina R Oliveira, Joaquim A F Vicente. Cerebrocrast promotes the cotransport of H+ and Cl- in rat liver mitochondria.
Mitochondrion.
2005 Oct; 5(5):341-51. doi:
10.1016/j.mito.2005.06.004. [PMID: 16099223] - Janīna Briede, Māra Stivriņa, Dzintra Stoldere, Egīls Bisenieks, Jānis Uldriķis, Jānis Poikāns, Natālija Makarova, Gunārs Duburs. Effect of new and known 1,4-dihydropyridine derivatives on blood glucose levels in normal and streptozotocin-induced diabetic rats.
Cell biochemistry and function.
2004 Jul; 22(4):219-24. doi:
10.1002/cbf.1091. [PMID: 15248181] - Janīna Briede, Kārlis Heidemanis, Inese Dabina, Gunārs Duburs. Effect of cerebrocrast on the function of human platelets and release of the arachidonic acid from plasma membrane.
Cell biochemistry and function.
2002 Jun; 20(2):177-81. doi:
10.1002/cbf.944. [PMID: 11979514] - T M Plotnikova, T G Bazhenova, M B Plotnikov, A S Saratikov. [The effect of cerebrocrast on the microcirculation in acute transient cerebral ischemia].
Eksperimental'naia i klinicheskaia farmakologiia.
1995 Mar; 58(2):27-9. doi:
". [PMID: 7773083]