Cellulose hydroxyethylate (BioDeep_00000177142)
human metabolite blood metabolite
代谢物信息卡片
1-{[3,4,5-tris(2-hydroxypropoxy)-6-{[4,5,6-tris(2-hydroxypropoxy)-2-[(2-hydroxypropoxy)methyl]oxan-3-yl]oxy}oxan-2-yl]methoxy}propan-2-ol
化学式: C36H70O19 (806.4511070000001)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(COCC1C(C(C(C(O1)OC2C(OC(C(C2OCC(C)O)OCC(C)O)OCC(C)O)COCC(C)O)OCC(C)O)OCC(C)O)OCC(C)O)O
InChI: InChI=1S/C36H70O19/c1-19(37)9-45-17-27-29(47-11-21(3)39)31(48-12-22(4)40)34(51-15-25(7)43)36(54-27)55-30-28(18-46-10-20(2)38)53-35(52-16-26(8)44)33(50-14-24(6)42)32(30)49-13-23(5)41/h19-44H,9-18H2,1-8H3
描述信息
D001697 - Biomedical and Dental Materials
同义名列表
10 个代谢物同义名
1-{[3,4,5-tris(2-hydroxypropoxy)-6-{[4,5,6-tris(2-hydroxypropoxy)-2-[(2-hydroxypropoxy)methyl]oxan-3-yl]oxy}oxan-2-yl]methoxy}propan-2-ol; Hydroxyethylcellulose, sodium salt; Cellulose hydroxyethylic acid; Cellulose hydroxyethylate; Hydroxyl ethyl cellulose; Minims artificial tears; Hydroxyethylcellulose; Natrosol 250; Aldiamed; Lacrigel
数据库引用编号
5 个数据库交叉引用编号
- PubChem: 4327536
- HMDB: HMDB0249797
- DrugBank: DB11602
- Wikipedia: Hydroxyethyl cellulose
- CAS: 1041187-47-6
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Negar Etminani-Esfahani, Abbas Rahmati. Effect of chain structures of monomer on hydroxyethyl cellulose-based superabsorbent properties and improvement of chickpeas plant growth of water deficit-stressed.
International journal of biological macromolecules.
2024 Jun; 269(Pt 2):131906. doi:
10.1016/j.ijbiomac.2024.131906. [PMID: 38679266] - Samah M El-Sayed, Hoda S El-Sayed, Ayat F Hashim, Ahmed M Youssef. Valorization of edible films based on chitosan/hydroxyethyl cellulose/olive leaf extract and TiO2-NPs for preserving sour cream.
International journal of biological macromolecules.
2024 May; 268(Pt 1):131727. doi:
10.1016/j.ijbiomac.2024.131727. [PMID: 38649073] - Abu Bakar Siddique, Dina Amr, Azhar Abbas, Lubna Zohra, Muhammad I Irfan, Ali Alhoshani, Saima Ashraf, Hatem M A Amin. Synthesis of hydroxyethylcellulose phthalate-modified silver nanoparticles and their multifunctional applications as an efficient antibacterial, photocatalytic and mercury-selective sensing agent.
International journal of biological macromolecules.
2024 Jan; 256(Pt 1):128009. doi:
10.1016/j.ijbiomac.2023.128009. [PMID: 37995781] - Hoang Nhan Ho, Hoang Hao Le, Thien Giap Le, Thi Hong Anh Duong, Viet Quynh Tram Ngo, Cong Thuan Dang, Van Minh Nguyen, Tuan Hiep Tran, Chien Ngoc Nguyen. Formulation and characterization of hydroxyethyl cellulose-based gel containing metronidazole-loaded solid lipid nanoparticles for buccal mucosal drug delivery.
International journal of biological macromolecules.
2022 Jan; 194(?):1010-1018. doi:
10.1016/j.ijbiomac.2021.11.161. [PMID: 34843817] - Laura Risaliti, Xuan Yu, Giulia Vanti, Maria Camilla Bergonzi, Meng Wang, Anna Rita Bilia. Hydroxyethyl cellulose hydrogel for skin delivery of khellin loaded in ascosomes: Characterization, in vitro/in vivo performance and acute toxicity.
International journal of biological macromolecules.
2021 May; 179(?):217-229. doi:
10.1016/j.ijbiomac.2021.02.206. [PMID: 33662425] - Jarosław Ciekot, Mateusz Psurski, Katarzyna Jurec, Janusz Boratyński. Hydroxyethylcellulose as a methotrexate carrier in anticancer therapy.
Investigational new drugs.
2021 02; 39(1):15-23. doi:
10.1007/s10637-020-00972-9. [PMID: 32643014] - Menglong Chu, Nianrong Feng, Hu An, Guanglin You, Changshun Mo, Hongyang Zhong, Liuru Pan, Dongying Hu. Design and validation of antibacterial and pH response of cationic guar gum film by combining hydroxyethyl cellulose and red cabbage pigment.
International journal of biological macromolecules.
2020 Nov; 162(?):1311-1322. doi:
10.1016/j.ijbiomac.2020.06.198. [PMID: 32599235] - Ana V Codina, Josefina Priotti, Darío Leonardi, María D Vasconi, Lucila I Hinrichsen, María C Lamas. Effect of Genotype and Sex of the Host on the Bioavailability of Novel Albendazole Microcrystals Based on Chitosan and Cellulose Derivatives.
AAPS PharmSciTech.
2020 May; 21(5):149. doi:
10.1208/s12249-020-01692-2. [PMID: 32435903] - Tiziana Esposito, Teresa Mencherini, Pasquale Del Gaudio, Giulia Auriemma, Silvia Franceschelli, Patrizia Picerno, Rita P Aquino, Francesca Sansone. Design and Development of Spray-Dried Microsystems to Improve Technological and Functional Properties of Bioactive Compounds from Hazelnut Shells.
Molecules (Basel, Switzerland).
2020 Mar; 25(6):. doi:
10.3390/molecules25061273. [PMID: 32168873] - Liz Nathalia Ibarra, Ana Elizabeth Oliveira de Araújo Alves, José Dijair Antonino, Guilherme Souza Prado, Clidia Eduarda Moreira Pinto, Carlos Ricardo Soccol, Érico Augusto Rosas de Vasconcelos, Maria Fátima Grossi-de-Sa. Enzymatic activity of a recombinant β-1,4-endoglucanase from the Cotton Boll Weevil (Anthonomus grandis) aiming second generation ethanol production.
Scientific reports.
2019 12; 9(1):19580. doi:
10.1038/s41598-019-56070-1. [PMID: 31862955] - Chengwei Wang, Haoyi Niu, Xiaoyu Ma, Hua Hong, Yuan Yuan, Changsheng Liu. Bioinspired, Injectable, Quaternized Hydroxyethyl Cellulose Composite Hydrogel Coordinated by Mesocellular Silica Foam for Rapid, Noncompressible Hemostasis and Wound Healing.
ACS applied materials & interfaces.
2019 Sep; 11(38):34595-34608. doi:
10.1021/acsami.9b08799. [PMID: 31464418] - U Jeffet, N Sterer. Effect of mucoadhesive agent HEC on herbal extracts retention and VSC producing bacteria reduction in an experimental oral biofilm.
Journal of breath research.
2019 03; 13(2):026004. doi:
10.1088/1752-7163/aaf6f7. [PMID: 30530941] - Khairy M Tohamy, Mostafa Mabrouk, Islam E Soliman, Hanan H Beherei, Mohamed A Aboelnasr. Novel alginate/hydroxyethyl cellulose/hydroxyapatite composite scaffold for bone regeneration: In vitro cell viability and proliferation of human mesenchymal stem cells.
International journal of biological macromolecules.
2018 Jun; 112(?):448-460. doi:
10.1016/j.ijbiomac.2018.01.181. [PMID: 29408578] - Débora Fretes Argenta, Juliana Bidone, Letícia Scherer Koester, Valquíria Link Bassani, Cláudia Maria Oliveira Simões, Helder Ferreira Teixeira. Topical Delivery of Coumestrol from Lipid Nanoemulsions Thickened with Hydroxyethylcellulose for Antiherpes Treatment.
AAPS PharmSciTech.
2018 Jan; 19(1):192-200. doi:
10.1208/s12249-017-0828-8. [PMID: 28681331] - Khawar Abbas, Muhammad Amin, Muhammad Ajaz Hussain, Muhammad Sher, Syed Nasir Abbas Bukhari, Ibrahim Jantan, Kevin J Edgar. Designing novel bioconjugates of hydroxyethyl cellulose and salicylates for potential pharmaceutical and pharmacological applications.
International journal of biological macromolecules.
2017 Oct; 103(?):441-450. doi:
10.1016/j.ijbiomac.2017.05.061. [PMID: 28526350] - Jenell S Coleman, Edward Fuchs, Wutyi S Aung, Mark A Marzinke, Rahul P Bakshi, Hans M L Spiegel, Jennifer Robinson, Craig W Hendrix. Feasibility of radiolabeled small molecule permeability as a quantitative measure of microbicide candidate toxicity.
Contraception.
2016 Apr; 93(4):331-336. doi:
10.1016/j.contraception.2016.01.002. [PMID: 26772905] - Nazia S Abbas, Muhammad Amin, Muhammad A Hussain, Kevin J Edgar, Muhammad N Tahir, Wolfgang Tremel. Extended release and enhanced bioavailability of moxifloxacin conjugated with hydrophilic cellulose ethers.
Carbohydrate polymers.
2016 Jan; 136(?):1297-306. doi:
10.1016/j.carbpol.2015.10.052. [PMID: 26572474] - Ayca Yildiz Pekoz, Meryem Sedef Erdal, Alper Okyar, Meltem Ocak, Fatma Tekeli, Engin Kaptan, Olcay Sagirli, Ahmet Araman. Preparation and in-vivo evaluation of dimenhydrinate buccal mucoadhesive films with enhanced bioavailability.
Drug development and industrial pharmacy.
2016; 42(6):916-25. doi:
10.3109/03639045.2015.1091470. [PMID: 26460061] - Dani Chatta, Lewis Cottrell, Bruce Burnett, Garry Laverty, Christopher McConville. The use of water-soluble mucoadhesive gels for the intravesical delivery of epirubicin to the bladder for the treatment of non-muscle-invasive bladder cancer.
The Journal of pharmacy and pharmacology.
2015 Oct; 67(10):1355-62. doi:
10.1111/jphp.12441. [PMID: 26076758] - Renata F J Tiossi, Juliana C Da Costa, Mariza A Miranda, Fabíola S G Praça, James D McChesney, Maria Vitória L B Bentley, Jairo K Bastos. In vitro and in vivo evaluation of the delivery of topical formulations containing glycoalkaloids of Solanum lycocarpum fruits.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
2014 Sep; 88(1):28-33. doi:
10.1016/j.ejpb.2014.01.010. [PMID: 24509413] - Sugandha Chahal, Sugandha Chalal, Shahitha Jahir Hussain Fathima, Mashitah Binti Mohd Yusoff. Biomimetic growth of bone-like apatite via simulated body fluid on hydroxyethyl cellulose/polyvinyl alcohol electrospun nanofibers.
Bio-medical materials and engineering.
2014; 24(1):799-806. doi:
10.3233/bme-130871. [PMID: 24211966] - Carole Lepilleur, Ann Giovannitti-Jensen, Carol Kyer. Use of statistical modeling to predict the effect of formulation composition on conditioning shampoo performance.
Journal of cosmetic science.
2013 Nov; 64(6):411-27. doi:
". [PMID: 24397880] - Shao-Ching Hung, Wallace Yokoyama, Hyunsook Kim, Glenn Bartley, William H K Anderson, David R Albers, Marsha L Langhorst, David M Williams, William Stott, Maciej Turowski, Scott A Young. Effects of cationic hydroxyethyl cellulose on dyslipidemia in hamsters.
Journal of agricultural and food chemistry.
2012 Nov; 60(44):11149-56. doi:
10.1021/jf302095c. [PMID: 23083223] - H Braunwarth, F H H Brill, D Hegeholz, P Hammerer. [The influence of viscosity of synthetic urine on the flow rate through catheters].
Der Urologe. Ausg. A.
2012 Mar; 51(3):403-8. doi:
10.1007/s00120-012-2807-8. [PMID: 22350017] - Scott A Young, Shao-Ching Hung, William H K Anderson, David R Albers, Marsha L Langhorst, Wallace Yokoyama. Effects of cationic hydroxyethyl cellulose on glucose metabolism and obesity in a diet-induced obesity mouse model.
Journal of diabetes.
2012 Mar; 4(1):85-94. doi:
10.1111/j.1753-0407.2011.00157.x. [PMID: 21895999] - J Pardeike, C Schmidt, I Volz, R H Müller. Nanostructured lipid carriers as delivery system for the phopholipase A2 inhibitors PX-18 and PX-13 for dermal application.
Die Pharmazie.
2011 May; 66(5):357-61. doi:
". [PMID: 21699069] - Yu Yuan Chieng, Shing Bor Chen. Rheological study of hydrophobically modified hydroxyethyl cellulose and phospholipid vesicles.
Journal of colloid and interface science.
2010 Sep; 349(1):236-45. doi:
10.1016/j.jcis.2010.05.058. [PMID: 20557897] - Anna V Svensson, Lynga Huang, Eric S Johnson, Tommy Nylander, Lennart Piculell. Surface deposition and phase behavior of oppositely charged polyion/surfactant ion complexes. 1. Cationic guar versus cationic hydroxyethylcellulose in mixtures with anionic surfactants.
ACS applied materials & interfaces.
2009 Nov; 1(11):2431-42. doi:
10.1021/am900378b. [PMID: 20356112] - S Tiwari, S Singh, M Rawat, R Tilak, B Mishra. L(9) orthogonal design assisted formulation and evaluation of chitosan-based buccoadhesive films of miconazole nitrate.
Current drug delivery.
2009 Jul; 6(3):305-16. doi:
10.2174/156720109788680921. [PMID: 19604145] - Sebastian Hahnel, Martin Rosentritt, Gerhard Handel, Ralf Bürgers. Influence of saliva substitute films on initial Streptococcus mutans adhesion to enamel and dental substrata.
Journal of dentistry.
2008 Dec; 36(12):977-83. doi:
10.1016/j.jdent.2008.08.004. [PMID: 18789569] - Maria Hrmova, Vladimir Farkas, Jelle Lahnstein, Geoffrey B Fincher. A Barley xyloglucan xyloglucosyl transferase covalently links xyloglucan, cellulosic substrates, and (1,3;1,4)-beta-D-glucans.
The Journal of biological chemistry.
2007 Apr; 282(17):12951-62. doi:
10.1074/jbc.m611487200. [PMID: 17329246] - Sabine Pestel, Hans-Juergen Martin, Gerd-Michael Maier, Brian Guth. Effect of commonly used vehicles on gastrointestinal, renal, and liver function in rats.
Journal of pharmacological and toxicological methods.
2006 Sep; 54(2):200-14. doi:
10.1016/j.vascn.2006.02.006. [PMID: 16567111] - Thierry Schmitz, Verena M Leitner, Andreas Bernkop-Schnürch. Oral heparin delivery: design and in vivo evaluation of a stomach-targeted mucoadhesive delivery system.
Journal of pharmaceutical sciences.
2005 May; 94(5):966-73. doi:
10.1002/jps.20311. [PMID: 15793802] - S K Jain, M K Chourasia, M Sabitha, R Jain, A K Jain, M Ashawat, A K Jha. Development and characterization of transdermal drug delivery systems for diltiazem hydrochloride.
Drug delivery.
2003 Jul; 10(3):169-77. doi:
10.1080/713840400. [PMID: 12944137] - D Petsch, T C Beeskow, F B Anspach, W D Deckwer. Membrane adsorbers for selective removal of bacterial endotoxin.
Journal of chromatography. B, Biomedical sciences and applications.
1997 May; 693(1):79-91. doi:
10.1016/s0378-4347(97)00013-3. [PMID: 9200521] - W A van der Reijden, M J Buijs, J J Damen, E C Veerman, J M ten Cate, A V Nieuw Amerongen. Influence of polymers for use in saliva substitutes on de- and remineralization of enamel in vitro.
Caries research.
1997; 31(3):216-23. doi:
10.1159/000262403. [PMID: 9165194] - Z Vitková, K Gardavská, J Cizmarik. Study of local anaesthetics. Part 136. Influence of auxiliary substances on the release of pentacaine from drug forms.
Acta poloniae pharmaceutica.
1996 Jul; 53(4):253-8. doi:
". [PMID: 9415194] - C Gulde, R Voigt. [Pharmaceutical and biologic availability of chlorpromazine from macromolecule-containing tablets].
Die Pharmazie.
1983 Aug; 38(8):542-6. doi:
NULL. [PMID: 6634924]