Cefodizime,(S) (BioDeep_00000177117)
human metabolite blood metabolite
代谢物信息卡片
3-({[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulphanyl}methyl)-7-[2-(2-imino-2,3-dihydro-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
化学式: C20H20N6O7S4 (584.027629)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 85.71%
分子结构信息
SMILES: CON=C(C(=O)NC1C2SCC(CSC3=NC(C)=C(CC(O)=O)S3)=C(N2C1=O)C(O)=O)C1=CSC(N)=N1
InChI: InChI=1S/C20H20N6O7S4/c1-7-10(3-11(27)28)37-20(22-7)36-5-8-4-34-17-13(16(30)26(17)14(8)18(31)32)24-15(29)12(25-33-2)9-6-35-19(21)23-9/h6,13,17H,3-5H2,1-2H3,(H2,21,23)(H,24,29)(H,27,28)(H,31,32)
描述信息
同义名列表
9 个代谢物同义名
3-({[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulphanyl}methyl)-7-[2-(2-imino-2,3-dihydro-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; 3-({[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulphanyl}methyl)-7-[2-(2-imino-2,3-dihydro-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; 3-({[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl)-7-[2-(2-imino-2,3-dihydro-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; 7-[2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-({[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; Cefodizime, dipotassium salt, (6R-(6alpha,7beta(Z)))-isomer; Cefodizime, disodium salt, (6R-(6alpha,7beta(Z)))-isomer; Cefodizime disodium; Cefodizime,(S); Modivid
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
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1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Lihong Li, Baozhong Ren, Jian Guo, Zhicang Zhang, Yuxing Cai, Jie Yin. Expression levels of blood platelet and C-reactive protein in patients with severely pneumonic and their predictive values for efficacy.
Cellular and molecular biology (Noisy-le-Grand, France).
2020 May; 66(2):105-110. doi:
10.14715/cmb/2020.66.2.17. [PMID: 32415935] - Bin Wang, Ruimin Bian, Chuanmei Wei, Shaowei Sun, Peimin Gao. [Cefodizime increases peripheral blood CD4/CD8 and Th1/Th2 ratios in senile patients with bacterial pneumonia].
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology.
2015 Apr; 31(4):528-31. doi:
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Journal of pharmaceutical and biomedical analysis.
2015 Mar; 107(?):325-32. doi:
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Drug metabolism and drug interactions.
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International journal of antimicrobial agents.
2006 Apr; 27(4):335-8. doi:
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Intensive care medicine.
2001 Nov; 27(11):1819-22. doi:
10.1007/s00134-001-1123-3. [PMID: 11810128] - G Blandino, I Milazzo, R Musumeci, V M Nicolosi, A Speciale, G Nicoletti. Comparative activity of cefodizime and ceftriaxone against respiratory pathogens in an in vitro pharmacodynamic model simulating concentration-time curves.
Journal of chemotherapy (Florence, Italy).
2000 Dec; 12(6):503-8. doi:
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2000 Aug; 12(4):306-13. doi:
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1999 Jan; 45(1):1-7. doi:
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1997 Dec; 37(12):1108-13. doi:
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Antimicrobial agents and chemotherapy.
1997 Oct; 41(10):2292-4. doi:
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Chemotherapy.
1997 Mar; 43(2):132-6. doi:
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The Journal of antimicrobial chemotherapy.
1997 Feb; 39(2):157-62. doi:
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International journal of clinical & laboratory research.
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Antimicrobial agents and chemotherapy.
1995 Sep; 39(9):2037-41. doi:
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Chemotherapy.
1995 May; 41(3):178-86. doi:
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Journal of clinical pharmacology.
1994 Nov; 34(11):1066-70. doi:
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The Japanese journal of antibiotics.
1994 Aug; 47(8):1071-6. doi:
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Hinyokika kiyo. Acta urologica Japonica.
1994 Apr; 40(4):365-9. doi:
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The Journal of pharmacology and experimental therapeutics.
1994 Jan; 268(1):65-73. doi:
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Arzneimittel-Forschung.
1993 Aug; 43(8):924-6. doi:
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The Journal of pharmacology and experimental therapeutics.
1993 Jun; 265(3):1301-12. doi:
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Biological & pharmaceutical bulletin.
1993 Mar; 16(3):273-9. doi:
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Journal of the Medical Association of Thailand = Chotmaihet thangphaet.
1992 May; 75(5):287-92. doi:
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The Journal of pharmacology and experimental therapeutics.
1992 Feb; 260(2):499-504. doi:
NULL. [PMID: 1738099] - D Brockmeier, E E Dagrosa. Pharmacokinetic profile of cefodizime.
Infection.
1992; 20 Suppl 1(?):S14-7. doi:
10.1007/bf01709944. [PMID: 1526669] - K Andrassy. Safety profile of cefodizime.
Infection.
1992; 20 Suppl 1(?):S36-40. doi:
10.1007/bf01709949. [PMID: 1526675] - M el Touny, M el Guinaidy, M Abdel Bary, L Osman, M S Sabbour. Pharmacokinetics of cefodizime in patients with liver cirrhosis and ascites.
Chemotherapy.
1992; 38(4):201-5. doi:
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Infection.
1992; 20 Suppl 1(?):S22-5. doi:
10.1007/bf01709946. [PMID: 1526671] - I O Auer, C Hardörfer, I Zimmermann. Cefodizime stimulates subpopulations of cells mediating spontaneous or antibody-dependent cytotoxicity in patients with bacterial infections.
Infection.
1992; 20 Suppl 1(?):S54-7. doi:
10.1007/bf01709954. [PMID: 1526679] - P M Shah, H Knothe. In vivo activity of cefodizime.
Infection.
1992; 20 Suppl 1(?):S9-13. doi:
10.1007/bf01709943. [PMID: 1526686] - N Itagaki, H Hasegawa, M Sakaguchi, T Oono, I Iwamoto, H Horiuchi, M Tsujino, K Takahashi, A Imada, A Horiuchi. [Pharmacokinetics of cefodizime in patients undergoing hemodialysis].
The Japanese journal of antibiotics.
1991 Dec; 44(12):1392-6. doi:
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The Journal of pharmacology and experimental therapeutics.
1991 Nov; 259(2):620-5. doi:
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The Japanese journal of antibiotics.
1991 Apr; 44(4):412-25. doi:
NULL. [PMID: 1880920] - H W Asbach. A randomized, dose comparison study of cefodizime in the treatment of lower urinary tract infections in women.
Infection.
1991 Mar; 19(2):85-7. doi:
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Journal of chemotherapy (Florence, Italy).
1991 Feb; 3(1):42-4. doi:
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Drugs under experimental and clinical research.
1991; 17(9):445-50. doi:
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Chemotherapy.
1991; 37(2):77-85. doi:
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The Journal of antimicrobial chemotherapy.
1990 Nov; 26 Suppl C(?):71-5. doi:
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The Journal of antimicrobial chemotherapy.
1990 Nov; 26 Suppl C(?):83-7. doi:
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The Journal of antimicrobial chemotherapy.
1990 Nov; 26 Suppl C(?):127-34. doi:
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The Journal of antimicrobial chemotherapy.
1990 Nov; 26 Suppl C(?):65-70. doi:
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The Journal of antimicrobial chemotherapy.
1990 Nov; 26 Suppl C(?):77-81. doi:
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The Journal of antimicrobial chemotherapy.
1990 Nov; 26 Suppl C(?):95-101. doi:
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Journal of pharmacobio-dynamics.
1990 Oct; 13(10):602-11. doi:
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The Japanese journal of antibiotics.
1990 Sep; 43(9):1603-13. doi:
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The Japanese journal of antibiotics.
1990 Jul; 43(7):1183-213. doi:
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The Japanese journal of antibiotics.
1990 Apr; 43(4):603-22. doi:
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The Japanese journal of antibiotics.
1989 Oct; 42(10):2069-81. doi:
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The Japanese journal of antibiotics.
1989 Oct; 42(10):2121-7. doi:
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The Japanese journal of antibiotics.
1989 Oct; 42(10):2090-7. doi:
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The Japanese journal of antibiotics.
1989 Oct; 42(10):2107-19. doi:
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The Japanese journal of antibiotics.
1989 Oct; 42(10):2082-9. doi:
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Arzneimittel-Forschung.
1989 Aug; 39(8):877-82. doi:
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The Japanese journal of antibiotics.
1989 Jun; 42(6):1366-80. doi:
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The Japanese journal of antibiotics.
1989 Jun; 42(6):1424-35. doi:
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The Japanese journal of antibiotics.
1989 Jun; 42(6):1279-85. doi:
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The Japanese journal of antibiotics.
1989 Jun; 42(6):1414-23. doi:
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The Japanese journal of antibiotics.
1989 Jun; 42(6):1293-305. doi:
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The Japanese journal of antibiotics.
1989 Jun; 42(6):1322-35. doi:
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The Japanese journal of antibiotics.
1989 Jun; 42(6):1400-13. doi:
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The Japanese journal of antibiotics.
1989 Jun; 42(6):1306-21. doi:
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The Japanese journal of antibiotics.
1989 Jun; 42(6):1336-45. doi:
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The Japanese journal of antibiotics.
1989 May; 42(5):1173-93. doi:
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Arzneimittel-Forschung.
1989 Jan; 39(1):31-3. doi:
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The Journal of antimicrobial chemotherapy.
1988 Aug; 22(2):229-35. doi:
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The Journal of toxicological sciences.
1988 Jun; 13 Suppl 1(?):43-90. doi:
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The Journal of toxicological sciences.
1988 Jun; 13 Suppl 1(?):329-60. doi:
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