4H-1,3,2-Benzodioxaphosphorin, 2-(2-methylphenoxy)-, 2-oxide (BioDeep_00000177068)
human metabolite blood metabolite
代谢物信息卡片
2-(2-methylphenoxy)-2,4-dihydro-1,3,2lambda5-benzodioxaphosphinin-2-one
化学式: C14H13O4P (276.0551)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=CC=CC=C1OP1(=O)OCC2=CC=CC=C2O1
InChI: InChI=1S/C14H13O4P/c1-11-6-2-4-8-13(11)17-19(15)16-10-12-7-3-5-9-14(12)18-19/h2-9H,10H2,1H3
描述信息
同义名列表
13 个代谢物同义名
2-(2-methylphenoxy)-2,4-dihydro-1,3,2lambda5-benzodioxaphosphinin-2-one; 2-(2-methylphenoxy)-4H-1,3,2lambda5-benzodioxaphosphinin-2-one; 4H-1,3,2-Benzodioxaphosphorin, 2-(2-methylphenoxy)-, 2-oxide; 2-(O-Cresyl)-4H-1-3-2-benzodioxaphosphorin-2-oxide; 2-(2-Cresyl)-4H-1-3-2-benzodioxaphosphorin-2-oxide; Saligenin cyclic-3-tolylphosphate; 0-Tosylsaligenin phosphate; 2-Tolylsaligenin phosphate; 2-Tosylsaligenin phosphate; Cresylsaligenin phosphate; 2-TSLPH; SCOTP; O-TSP
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Ali Sajjad Bokaei, Omid Sofalian, Behzad Sorkhilalehloo, Ali Asghari, Alireza Pour-Aboughadareh. Deciphering the level of genetic diversity in some aegilops species using CAAT box-derived polymorphism (CBDP) and start codon target polymorphism (SCoT) markers.
Molecular biology reports.
2023 May; ?(?):. doi:
10.1007/s11033-023-08488-0. [PMID: 37219668] - Mariya S Liyasova, Lawrence M Schopfer, Oksana Lockridge. Cresyl saligenin phosphate makes multiple adducts on free histidine, but does not form an adduct on histidine 438 of human butyrylcholinesterase.
Chemico-biological interactions.
2013 Mar; 203(1):103-7. doi:
10.1016/j.cbi.2012.07.006. [PMID: 22898212] - Mariya S Liyasova, Lawrence M Schopfer, Oksana Lockridge. Cresyl saligenin phosphate, an organophosphorus toxicant, makes covalent adducts with histidine, lysine, and tyrosine residues of human serum albumin.
Chemical research in toxicology.
2012 Aug; 25(8):1752-61. doi:
10.1021/tx300215g. [PMID: 22793878] - Ellen G Duysen, John R Cashman, Lawrence M Schopfer, Florian Nachon, Patrick Masson, Oksana Lockridge. Differential sensitivity of plasma carboxylesterase-null mice to parathion, chlorpyrifos and chlorpyrifos oxon, but not to diazinon, dichlorvos, diisopropylfluorophosphate, cresyl saligenin phosphate, cyclosarin thiocholine, tabun thiocholine, and carbofuran.
Chemico-biological interactions.
2012 Feb; 195(3):189-98. doi:
10.1016/j.cbi.2011.12.006. [PMID: 22209767] - Judit Marsillach, Rebecca J Richter, Jerry H Kim, Richard C Stevens, Michael J MacCoss, Daniela Tomazela, Stephanie M Suzuki, Lawrence M Schopfer, Oksana Lockridge, Clement E Furlong. Biomarkers of organophosphorus (OP) exposures in humans.
Neurotoxicology.
2011 Oct; 32(5):656-60. doi:
10.1016/j.neuro.2011.06.005. [PMID: 21767566] - Teresa L Garrett, Christine M Rapp, Robert D Grubbs, John J Schlager, James B Lucot. A murine model for sarin exposure using the carboxylesterase inhibitor CBDP.
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Analytical biochemistry.
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Molecular pharmacology.
2006 Sep; 70(3):1121-31. doi:
10.1124/mol.106.026179. [PMID: 16801396] - W D Dettbarn, Z P Yang, D Milatovic. Different role of carboxylesterases in toxicity and tolerance to paraoxon and DFP.
Chemico-biological interactions.
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10.1016/s0009-2797(99)00057-5. [PMID: 10421482] - Z P Yang, W D Dettbarn. Prevention of tolerance to the organophosphorus anticholinesterase paraoxon with carboxylesterase inhibitors.
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10.1016/s0006-2952(97)00650-3. [PMID: 10076534] - R M Welch, A Brown, J Ravitch, R Dahl. The in vitro degradation of cisatracurium, the R, cis-R'-isomer of atracurium, in human and rat plasma.
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1995 Aug; 58(2):132-42. doi:
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1991; 15(1):85-8. doi:
10.1016/s0149-7634(05)80096-x. [PMID: 2052204] - J G Clement, N Erhardt. Serum carboxylesterase activity in various strains of rats: sensitivity to inhibition by CBDP (2-/o-cresyl/4H:1:3:2-benzodioxaphosphorin-2-oxide).
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