Carboxyethylphosphoramide (BioDeep_00000177031)

   

human metabolite blood metabolite


代谢物信息卡片


3-[(diaminophosphoryl)amino]propanoic acid

化学式: C3H10N3O3P (167.046)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(blood) 100%

分子结构信息

SMILES: C(CNP(=O)(N)N)C(=O)O
InChI: InChI=1S/C3H10N3O3P/c4-10(5,9)6-2-1-3(7)8/h1-2H2,(H,7,8)(H5,4,5,6,9)



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Feng Bai, Charles H Fraga, Michael Tagen, Paula Schaiquevich, Nikolaus Hagedorn, Clinton F Stewart. Simultaneous determination of cyclophosphamide and carboxyethylphosphoramide mustard in human plasma using online extraction and electrospray tandem mass spectrometry (HTLC-ESI-MS/MS). Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2009 Jun; 877(18-19):1709-15. doi: 10.1016/j.jchromb.2009.04.025. [PMID: 19447687]
  • J S McCune, A Batchelder, K A Guthrie, R Witherspoon, F R Appelbaum, B Phillips, P Vicini, D H Salinger, G B McDonald. Personalized dosing of cyclophosphamide in the total body irradiation-cyclophosphamide conditioning regimen: a phase II trial in patients with hematologic malignancy. Clinical pharmacology and therapeutics. 2009 Jun; 85(6):615-22. doi: 10.1038/clpt.2009.27. [PMID: 19295506]
  • Jeannine S McCune, Ami Batchelder, H Joachim Deeg, Ted Gooley, Scott Cole, Brian Phillips, H Gary Schoch, George B McDonald. Cyclophosphamide following targeted oral busulfan as conditioning for hematopoietic cell transplantation: pharmacokinetics, liver toxicity, and mortality. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 2007 Jul; 13(7):853-62. doi: 10.1016/j.bbmt.2007.03.012. [PMID: 17580264]
  • David H Salinger, Jeannine S McCune, Aaron G Ren, Danny D Shen, John T Slattery, Brian Phillips, George B McDonald, Paolo Vicini. Real-time dose adjustment of cyclophosphamide in a preparative regimen for hematopoietic cell transplant: a Bayesian pharmacokinetic approach. Clinical cancer research : an official journal of the American Association for Cancer Research. 2006 Aug; 12(16):4888-98. doi: 10.1158/1078-0432.ccr-05-2079. [PMID: 16914577]
  • M E de Jonge, A D R Huitema, J H Beijnen, S Rodenhuis. High exposures to bioactivated cyclophosphamide are related to the occurrence of veno-occlusive disease of the liver following high-dose chemotherapy. British journal of cancer. 2006 May; 94(9):1226-30. doi: 10.1038/sj.bjc.6603097. [PMID: 16622453]
  • Thomas F Kalhorn, William N Howald, Scott Cole, Brian Phillips, Joanne Wang, John T Slattery, Jeannine S McCune. Rapid quantitation of cyclophosphamide metabolites in plasma by liquid chromatography-mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2006 May; 835(1-2):105-13. doi: 10.1016/j.jchromb.2006.03.022. [PMID: 16581318]
  • Jeannine S McCune, Denise Adams, Alan C Homans, Ann Guillot, Lisa Iacono, Clinton F Stewart. Cyclophosphamide disposition in an anephric child. Pediatric blood & cancer. 2006 Jan; 46(1):99-104. doi: 10.1002/pbc.20558. [PMID: 16155930]
  • George B McDonald, John T Slattery, Michelle E Bouvier, Song Ren, Ami L Batchelder, Thomas F Kalhorn, H Gary Schoch, Claudio Anasetti, Ted Gooley. Cyclophosphamide metabolism, liver toxicity, and mortality following hematopoietic stem cell transplantation. Blood. 2003 Mar; 101(5):2043-8. doi: 10.1182/blood-2002-06-1860. [PMID: 12406916]