Carbohydrazide (BioDeep_00000177010)

   

human metabolite blood metabolite


代谢物信息卡片


Hydrazide hydrazinecarboxylic acid

化学式: CH6N4O (90.05415860000001)
中文名称: 碳酰肼
谱图信息: 最多检出来源 Homo sapiens(blood) 92.19%

分子结构信息

SMILES: C(=O)(NN)NN
InChI: InChI=1S/CH6N4O/c2-4-1(6)5-3/h2-3H2,(H2,4,5,6)

描述信息

同义名列表

19 个代谢物同义名

Hydrazide hydrazinecarboxylic acid; Hydrazide hydrazinecarboxylate; N,N-diaminocarbamimidic acid; N-Aminohydrazine carboxamide; N-Aminohydrazinecarboxamide; Carbonylbis-hydrazine; Carbonic dihydrazide; Hydrazinecarboxamide; 4-Aminosemicarbazide; Carbonodihydrazide; Carbodihydrazide; Carbonohydrazide; 1,3-Diaminourea; Carbonohydrazid; N,N-diaminourea; carbohydrazide; Diaminourea; Carbazide; Cabazide



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Prerana B Jadhav, Shailaja B Jadhav, Mehrukh Zehravi, Mohammad S Mubarak, Fahadul Islam, Philippe Jeandet, Sharuk L Khan, Nazmul Hossain, Salma Rashid, Long Chiau Ming, Md Moklesur Rahman Sarker, Mohd Fahami Nur Azlina. Virtual Screening, Synthesis, and Biological Evaluation of Some Carbohydrazide Derivatives as Potential DPP-IV Inhibitors. Molecules (Basel, Switzerland). 2022 Dec; 28(1):. doi: 10.3390/molecules28010149. [PMID: 36615348]
  • Saman Taj, Matloob Ahmad, Usman Ali Ashfaq. Exploring of novel 4-hydroxy-2H-benzo[e][1,2]thiazine-3-carbohydrazide 1,1-dioxide derivative as a dual inhibitor of α-glucosidase and α-amylase: Molecular docking, biochemical, enzyme kinetic and in-vivo mouse model study. International journal of biological macromolecules. 2022 May; 207(?):507-521. doi: 10.1016/j.ijbiomac.2022.03.023. [PMID: 35276296]
  • Jian-Jun Zhu, Pei-Yi Wang, Zhou-Qing Long, Shu-Zhen Xiang, Jun-Rong Zhang, Zhen-Xing Li, Yuan-Yuan Wu, Wu-Bin Shao, Xiang Zhou, Li-Wei Liu, Song Yang. Design, Synthesis, and Biological Profiles of Novel 1,3,4-Oxadiazole-2-carbohydrazides with Molecular Diversity. Journal of agricultural and food chemistry. 2022 Mar; 70(9):2825-2838. doi: 10.1021/acs.jafc.1c07190. [PMID: 35201749]
  • Francisco Mainardi Martins, Otávio Augusto Chaves, Thiago V Acunha, Daiane Roman, Bernardo Almeida Iglesias, Davi Fernando Back. Helical water-soluble NiII complexes with pyridoxal ligand derivatives: Structural evaluation and interaction with biomacromolecules. Journal of inorganic biochemistry. 2021 02; 215(?):111307. doi: 10.1016/j.jinorgbio.2020.111307. [PMID: 33341589]
  • Yuan-Yuan Wu, Wu-Bin Shao, Jian-Jun Zhu, Zhou-Qing Long, Li-Wei Liu, Pei-Yi Wang, Zhong Li, Song Yang. Novel 1,3,4-Oxadiazole-2-carbohydrazides as Prospective Agricultural Antifungal Agents Potentially Targeting Succinate Dehydrogenase. Journal of agricultural and food chemistry. 2019 Dec; 67(50):13892-13903. doi: 10.1021/acs.jafc.9b05942. [PMID: 31774673]
  • Mariane C Bagatin, Andrew M F Rozada, Franciele A V Rodrigues, Paulo S A Bueno, Jessyka L Santos, Fernanda Canduri, Érika S Kioshima, Flavio A V Seixas, Ernani A Basso, Gisele F Gauze. New 4-methoxy-naphthalene derivatives as promisor antifungal agents for paracoccidioidomycosis treatment. Future microbiology. 2019 02; 14(?):235-245. doi: 10.2217/fmb-2018-0276. [PMID: 30663901]
  • Eduardo Hernández-Vázquez, Sandybel Salgado-Barrera, Juan José Ramírez-Espinosa, Samuel Estrada-Soto, Francisco Hernández-Luis. Synthesis and molecular docking of N'-arylidene-5-(4-chlorophenyl)-1-(3,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carbohydrazides as novel hypoglycemic and antioxidant dual agents. Bioorganic & medicinal chemistry. 2016 05; 24(10):2298-306. doi: 10.1016/j.bmc.2016.04.007. [PMID: 27079123]
  • Ebtehal S Al-Abdullah, Hanaa M Al-Tuwaijri, Hanan M Hassan, Monirah A Al-Alshaikh, Elsayed E Habib, Ali A El-Emam. Synthesis, Antimicrobial and Hypoglycemic Activities of Novel N-(1-Adamantyl)carbothioamide Derivatives. Molecules (Basel, Switzerland). 2015 May; 20(5):8125-43. doi: 10.3390/molecules20058125. [PMID: 25955889]
  • Yongxian Liu, Hongjian Song, Yuanqiong Huang, Jiarui Li, Sheng Zhao, Yuchuan Song, Peiwen Yang, Zhixin Xiao, Yuxiu Liu, Yongqiang Li, Hui Shang, Qingmin Wang. Design, synthesis, and antiviral, fungicidal, and insecticidal activities of tetrahydro-β-carboline-3-carbohydrazide derivatives. Journal of agricultural and food chemistry. 2014 Oct; 62(41):9987-99. doi: 10.1021/jf503794g. [PMID: 25280351]
  • Plínio Cunha Sathler, André Luiz Lourenço, Carlos Rangel Rodrigues, Luiz Cláudio Rodrigues Pereira da Silva, Lucio Mendes Cabral, Alessandro Kappel Jordão, Anna Cláudia Cunha, Maria Cecília Bastos Vieira, Vitor Francisco Ferreira, Carla Eponina Carvalho-Pinto, Hye Chung Kang, Helena Carla Castro. In vitro and in vivo analysis of the antithrombotic and toxicological profile of new antiplatelets N-acylhydrazone derivatives and development of nanosystems: determination of novel NAH derivatives antiplatelet and nanotechnological approach. Thrombosis research. 2014 Aug; 134(2):376-83. doi: 10.1016/j.thromres.2014.05.009. [PMID: 24877647]
  • Dimitra Hadjipavlou-Litina, Abdelouahid Samadi, Mercedes Unzeta, José Marco-Contelles. Analysis of the antioxidant properties of differently substituted 2- and 3-indolyl carbohydrazides and related derivatives. European journal of medicinal chemistry. 2013 May; 63(?):670-4. doi: 10.1016/j.ejmech.2013.03.014. [PMID: 23567956]
  • Ivana Milic, Ralf Hoffmann, Maria Fedorova. Simultaneous detection of low and high molecular weight carbonylated compounds derived from lipid peroxidation by electrospray ionization-tandem mass spectrometry. Analytical chemistry. 2013 Jan; 85(1):156-62. doi: 10.1021/ac302356z. [PMID: 23186270]
  • Paolo Mombelli, Matthias C Witschel, Anthoni W van Zijl, Julie G Geist, Matthias Rottmann, Céline Freymond, Franz Röhl, Marcel Kaiser, Victoria Illarionova, Markus Fischer, Isabella Siepe, W Bernd Schweizer, Reto Brun, François Diederich. Identification of 1,3-diiminoisoindoline carbohydrazides as potential antimalarial candidates. ChemMedChem. 2012 Jan; 7(1):151-8. doi: 10.1002/cmdc.201100441. [PMID: 22095896]
  • Karen S Charret, Raquel F Rodrigues, Alice M R Bernardino, Adriana O Gomes, Adriana V Carvalho, Marilene M Canto-Cavalheiro, Leonor Leon, Veronica F Amaral. Effect of oral treatment with pyrazole carbohydrazide derivatives against murine infection by Leishmania amazonensis. The American journal of tropical medicine and hygiene. 2009 Apr; 80(4):568-73. doi: 10.4269/ajtmh.2009.80.568. [PMID: 19346377]
  • Dan Zhao, N D Sonawane, Marc H Levin, Baoxue Yang. Comparative transport efficiencies of urea analogues through urea transporter UT-B. Biochimica et biophysica acta. 2007 Jul; 1768(7):1815-21. doi: 10.1016/j.bbamem.2007.04.010. [PMID: 17506977]
  • Agneta H Plamboeck, Todd E Dawson, Louise M Egerton-Warburton, Malcolm North, Thomas D Bruns, José Ignacio Querejeta. Water transfer via ectomycorrhizal fungal hyphae to conifer seedlings. Mycorrhiza. 2007 Jul; 17(5):439-447. doi: 10.1007/s00572-007-0119-4. [PMID: 17333298]
  • Jason M Elliott, Robert W Carling, Gary G Chicchi, James Crawforth, Peter H Hutson, A Brian Jones, Sarah Kelly, Rose Marwood, Georgina Meneses-Lorente, Elena Mezzogori, Fraser Murray, Michael Rigby, Inmaculada Royo, Michael G N Russell, Duncan Shaw, Bindi Sohal, Kwei Lan Tsao, Brian Williams. N',2-diphenylquinoline-4-carbohydrazide based NK3 receptor antagonists II. Bioorganic & medicinal chemistry letters. 2006 Nov; 16(22):5752-6. doi: 10.1016/j.bmcl.2006.08.085. [PMID: 16950617]
  • Jason M Elliott, Robert W Carling, Mark Chambers, Gary G Chicchi, Peter H Hutson, A Brian Jones, Angus MacLeod, Rose Marwood, Georgina Meneses-Lorente, Elena Mezzogori, Fraser Murray, Michael Rigby, Inmaculada Royo, Michael G N Russell, Bindi Sohal, Kwei Lan Tsao, Brian Williams. N',2-diphenylquinoline-4-carbohydrazide based NK3 receptor antagonists. Bioorganic & medicinal chemistry letters. 2006 Nov; 16(22):5748-51. doi: 10.1016/j.bmcl.2006.08.086. [PMID: 16950620]
  • Willem F Wolkers, Sheri A Looper, Ray A Fontanilla, Nelly M Tsvetkova, Fern Tablin, John H Crowe. Temperature dependence of fluid phase endocytosis coincides with membrane properties of pig platelets. Biochimica et biophysica acta. 2003 Jun; 1612(2):154-63. doi: 10.1016/s0005-2736(03)00114-7. [PMID: 12787933]
  • Helen A Atkinson, Alison Daniels, Nick D Read. Live-cell imaging of endocytosis during conidial germination in the rice blast fungus, Magnaporthe grisea. Fungal genetics and biology : FG & B. 2002 Dec; 37(3):233-44. doi: 10.1016/s1087-1845(02)00535-2. [PMID: 12431458]
  • Y Jitsuyama, T Suzuki, T Harada, S Fujikawa. Loading process of sugars into cabbage petiole and asparagus shoot apex cells by incubation with hypertonic sugar solutions. Protoplasma. 2001; 217(4):205-16. doi: 10.1007/bf01283402. [PMID: 11732313]