Bornaprolol (BioDeep_00000176800)
human metabolite blood metabolite
代谢物信息卡片
化学式: C19H29NO2 (303.2198)
中文名称: 波那洛尔
谱图信息:
最多检出来源 Homo sapiens(blood) 95.27%
分子结构信息
SMILES: CC(C)NCC(COC1=CC=CC=C1C2CC3CCC2C3)O
InChI: InChI=1S/C19H29NO2/c1-13(2)20-11-16(21)12-22-19-6-4-3-5-17(19)18-10-14-7-8-15(18)9-14/h3-6,13-16,18,20-21H,7-12H2,1-2H3
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- S Urien, Y Giroud, R S Tsai, P A Carrupt, F Brée, B Testa, J P Tillement. Mechanism of ligand binding to alpha 1-acid glycoprotein (orosomucoid): correlated thermodynamic factors and molecular parameters of polarity.
The Biochemical journal.
1995 Mar; 306 ( Pt 2)(?):545-9. doi:
10.1042/bj3060545. [PMID: 7887909] - G Cheymol, A Cheymol, C Jozefczak, V Lecoq, B Lecoq, P Jaillon. Pharmacokinetic characteristics of bornaprolol in healthy volunteers.
Xenobiotica; the fate of foreign compounds in biological systems.
1990 Aug; 20(8):855-60. doi:
10.3109/00498259009046899. [PMID: 1977241] - J C Bedran-de-Castro, S L Petrovic, S M McCann. Involvement of beta-adrenergic receptors in the differential release of gonadotropins in acutely orchidectomized rats.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.
1990; 23(10):1025-7. doi:
NULL. [PMID: 1983168] - S L Petrovic, J C Bedran de Castro, S M McCann. Beta-adrenergic blockers decrease levels of luteinizing hormone in plasma of orchidectomized rats.
Biology of reproduction.
1987 Oct; 37(3):539-45. doi:
10.1095/biolreprod37.3.539. [PMID: 2890382] - G Cheymol, P Jaillon, B Lecoq, V Lecoq, A Cheymol, M Krumenacker. Cardiovascular beta-adrenergic blocking effects of bornaprolol in humans: relation to dose and plasma concentration.
Journal of cardiovascular pharmacology.
1987 Jun; 9(6):694-8. doi:
10.1097/00005344-198706000-00009. [PMID: 2442536] - P Riant, S Urien, E Albengres, J C Duche, J P Tillement. High plasma protein binding as a parameter in the selection of betablockers for lactating women.
Biochemical pharmacology.
1986 Dec; 35(24):4579-81. doi:
10.1016/0006-2952(86)90783-5. [PMID: 2878668] - S L Petrovic, J C Bedran De Castro, S M McCann. Beta-adrenergic agonists increase amplitude of LH release in orchidectomized rats.
The American journal of physiology.
1986 Sep; 251(3 Pt 1):E316-21. doi:
10.1152/ajpendo.1986.251.3.e316. [PMID: 2875653] - R A Shastri, J Barre, G Houin, C Hamberger, J P Tillement. Binding of bornaprolol to human serum proteins and blood cells.
International journal of clinical pharmacology, therapy, and toxicology.
1986 Jul; 24(7):351-6. doi:
NULL. [PMID: 3733286] - C Thuillez, C Richer, P Duhazé, L Bergougnan, J F Giudicelli. Beta-adrenoceptor blocking effects and plasma levels of bornaprolol and propranolol in man.
European journal of clinical pharmacology.
1985; 29(4):405-11. doi:
10.1007/bf00613453. [PMID: 3912184] - N Bernard, G Cuisinaud, C Jozefczak, M Seccia, N Ferry, J Sassard. Sensitive gas chromatographic method for the determination in plasma of FM 24, 1-(2-exo-bicyclo[2,2,1]hept-2-ylphenoxy)-3[(1-methylethyl)amino]-2-propanol, a new beta-adrenoceptor blocking agent.
Journal of chromatography.
1980 Jul; 183(1):99-103. doi:
10.1016/s0378-4347(00)81405-x. [PMID: 6105161]
