2,2'-Dipicolylamine (BioDeep_00000176732)
human metabolite blood metabolite
代谢物信息卡片
化学式: C12H13N3 (199.1109418)
中文名称: 2,2-二吡啶甲基胺
谱图信息:
最多检出来源 Mus musculus(blood) 33.33%
分子结构信息
SMILES: C(NCC1=CC=CC=N1)C1=CC=CC=N1
InChI: InChI=1S/C12H13N3/c1-3-7-14-11(5-1)9-13-10-12-6-2-4-8-15-12/h1-8,13H,9-10H2
描述信息
同义名列表
数据库引用编号
6 个数据库交叉引用编号
- PubChem: 73759
- HMDB: HMDB0249259
- ChEMBL: CHEMBL1650627
- chemspider: 66400
- CAS: 29227-68-7
- CAS: 1539-42-0
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Yu Guo, Xi He, Rui-Mo Zhao, Hui-Zhen Yang, Zheng Huang, Ji Zhang, Xiao-Qi Yu. Zn-dipicolylamine-based reactive oxygen species-responsive lipids for siRNA delivery and in vivo colitis treatment.
Acta biomaterialia.
2022 07; 147(?):287-298. doi:
10.1016/j.actbio.2022.04.033
. [PMID: 35489607] - Lindelwa Satyo, Daniel G Amoako, Anou M Somboro, Sphelele C Sosibo, Hezekiel M Kumalo, Ndumiso N Mhlongo, Rene B Khan. Molecular Insights Into Di(2-Picolyl) Amine-Induced Cytotoxicity and Apoptosis in Human Kidney (HEK293) Cells.
International journal of toxicology.
2020 Jul; 39(4):341-351. doi:
10.1177/1091581820921180
. [PMID: 32351145] - Rong-Chuan Su, Qiang Liu, Wen-Jing Yi, Zhi-Gang Zhao. Zn(II)-dipicolylamine-based metallo-lipids as novel non-viral gene vectors.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry.
2017 Aug; 22(6):867-879. doi:
10.1007/s00775-017-1465-0
. [PMID: 28508949] - Umme Ayesa, Brian D Gray, Koon Y Pak, Parkson Lee-Gau Chong. Liposomes Containing Lipid-Soluble Zn(II)-Bis-dipicolylamine Derivatives Show Potential To Be Targeted to Phosphatidylserine on the Surface of Cancer Cells.
Molecular pharmaceutics.
2017 01; 14(1):147-156. doi:
10.1021/acs.molpharmaceut.6b00760
. [PMID: 28043132] - Xiaofeng Bao, Qiansheng Cao, Yazhou Xu, Yuanxue Gao, Yuan Xu, Xuemei Nie, Baojing Zhou, Tao Pang, Jing Zhu. Synthesis and evaluation of a new Rhodamine B and Di(2-picolyl)amine conjugate as a highly sensitive and selective chemosensor for Al3+ and its application in living-cell imaging.
Bioorganic & medicinal chemistry.
2015 Feb; 23(4):694-702. doi:
10.1016/j.bmc.2014.12.070
. [PMID: 25614113] - Serhan Turkyilmaz, Douglas R Rice, Rachael Palumbo, Bradley D Smith. Selective recognition of anionic cell membranes using targeted liposomes coated with zinc(ii)-bis(dipicolylamine) affinity units.
Organic & biomolecular chemistry.
2014 Aug; 12(30):5645-55. doi:
10.1039/c4ob00924j
. [PMID: 24962330] - Pui-Kei Lee, Wendell Ho-Tin Law, Hua-Wei Liu, Kenneth Kam-Wing Lo. Luminescent cyclometalated iridium(III) polypyridine di-2-picolylamine complexes: synthesis, photophysics, electrochemistry, cation binding, cellular internalization, and cytotoxic activity.
Inorganic chemistry.
2011 Sep; 50(17):8570-9. doi:
10.1021/ic201153d
. [PMID: 21834537] - Na Shao, Hao Wang, Xiadi Gao, Ronghua Yang, Winghong Chan. Spiropyran-based fluorescent anion probe and its application for urinary pyrophosphate detection.
Analytical chemistry.
2010 Jun; 82(11):4628-36. doi:
10.1021/ac1008089
. [PMID: 20459115]