Benzyl trisulfide (BioDeep_00000176598)

   

human metabolite blood metabolite


代谢物信息卡片


Dibenzyl trisulfide

化学式: C14H14S3 (278.0257604)
中文名称: 三硫二苄基
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(SSSCC1=CC=CC=C1)C1=CC=CC=C1
InChI: InChI=1S/C14H14S3/c1-3-7-13(8-4-1)11-15-17-16-12-14-9-5-2-6-10-14/h1-10H,11-12H2

描述信息

同义名列表

5 个代谢物同义名

Dibenzyl trisulfide; Dibenzyltrisulphane; Benzyl trisulphide; dibenzyltrisulfane; Benzyl trisulfide



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Jonathan Wooten, Nicole Mavingire, Cristina A Araújo, Joyce Aja, Shaniece Wauchope, Rupika Delgoda, Eileen Brantley. Dibenzyl trisulfide induces caspase-independent death and lysosomal membrane permeabilization of triple-negative breast cancer cells. Fitoterapia. 2022 Jul; 160(?):105203. doi: 10.1016/j.fitote.2022.105203. [PMID: 35489582]
  • Nishani Clarke, William Irvine. In Silico Design and SAR Study of Dibenzyl Trisulfide Analogues for Improved CYP1A1 Inhibition. ChemistryOpen. 2022 05; 11(5):e202200016. doi: 10.1002/open.202200016. [PMID: 35610057]
  • Shaniece Wauchope, Monika A Roy, William Irvine, Isaac Morrison, Eileen Brantley, Maxine Gossell-Williams, Alicia R Timme-Laragy, Rupika Delgoda. Dibenzyl trisulfide binds to and competitively inhibits the cytochrome P450 1A1 active site without impacting the expression of the aryl hydrocarbon receptor. Toxicology and applied pharmacology. 2021 05; 419(?):115502. doi: 10.1016/j.taap.2021.115502. [PMID: 33774063]
  • J Murray, D Picking, A Lamm, J McKenzie, S Hartley, C Watson, L Williams, H Lowe, R Delgoda. Significant inhibitory impact of dibenzyl trisulfide and extracts of Petiveria alliacea on the activities of major drug-metabolizing enzymes in vitro: An assessment of the potential for medicinal plant-drug interactions. Fitoterapia. 2016 Jun; 111(?):138-46. doi: 10.1016/j.fitote.2016.04.011. [PMID: 27105957]
  • Henry I C Lowe, Caroline O B Facey, Ngeh J Toyang, Joseph L Bryant. Specific RSK kinase inhibition by dibenzyl trisulfide and implication for therapeutic treatment of cancer. Anticancer research. 2014 Apr; 34(4):1637-41. doi: . [PMID: 24692692]
  • J A Rosado-Aguilar, A Aguilar-Caballero, R I Rodriguez-Vivas, R Borges-Argaez, Z Garcia-Vazquez, M Mendez-Gonzalez. Acaricidal activity of extracts from Petiveria alliacea (Phytolaccaceae) against the cattle tick, Rhipicephalus (Boophilus) microplus (Acari: ixodidae). Veterinary parasitology. 2010 Mar; 168(3-4):299-303. doi: 10.1016/j.vetpar.2009.11.022. [PMID: 20042296]
  • L A D Williams, E N Barton, W Kraus, H Rösner. Implications of dibenzyl trisulphide for disease treatment based on its mode of action. The West Indian medical journal. 2009 Nov; 58(5):407-9. doi: ". [PMID: 20441056]
  • Claudia Urueña, Claudia Cifuentes, Diana Castañeda, Amparo Arango, Punit Kaur, Alexzander Asea, Susana Fiorentino. Petiveria alliacea extracts uses multiple mechanisms to inhibit growth of human and mouse tumoral cells. BMC complementary and alternative medicine. 2008 Nov; 8(?):60. doi: 10.1186/1472-6882-8-60. [PMID: 19017389]
  • L A D Williams, H Rosner, H G Levy, E N Barton. A critical review of the therapeutic potential of dibenzyl trisulphide isolated from Petiveria alliacea L (guinea hen weed, anamu). The West Indian medical journal. 2007 Jan; 56(1):17-21. doi: 10.1590/s0043-31442007000100004. [PMID: 17621839]
  • Seokwon Kim, Roman Kubec, Rabi A Musah. Antibacterial and antifungal activity of sulfur-containing compounds from Petiveria alliacea L. Journal of ethnopharmacology. 2006 Mar; 104(1-2):188-92. doi: 10.1016/j.jep.2005.08.072. [PMID: 16229980]
  • L A D Williams, H Rösner, W Möller, J Conrad, J P Nkurunziza, W Kraus. In vitro anti-proliferation/cytotoxic activity of sixty natural products on the human SH-SY5Y neuroblastoma cells with specific reference to dibenzyl trisulphide. The West Indian medical journal. 2004 Sep; 53(4):208-19. doi: ". [PMID: 15622673]
  • L A D Williams, E Vasquez, I Klaiber, W Kraus, H Rosner. A sulfonic anhydride derivative from dibenzyl trisulphide with agro-chemical activities. Chemosphere. 2003 Jun; 51(8):701-6. doi: 10.1016/s0045-6535(03)00160-7. [PMID: 12668029]
  • H Rösner, L A Williams, A Jung, W Kraus. Disassembly of microtubules and inhibition of neurite outgrowth, neuroblastoma cell proliferation, and MAP kinase tyrosine dephosphorylation by dibenzyl trisulphide. Biochimica et biophysica acta. 2001 Aug; 1540(2):166-77. doi: 10.1016/s0167-4889(01)00129-x. [PMID: 11513978]
  • E Mata-Greenwood, A Ito, H Westenburg, B Cui, R G Mehta, A D Kinghorn, J M Pezzuto. Discovery of novel inducers of cellular differentiation using HL-60 promyelocytic cells. Anticancer research. 2001 May; 21(3B):1763-70. doi: ". [PMID: 11497257]