Benzoylpaeoniflorin (BioDeep_00000176587)

Main id: BioDeep_00000230458

 

human metabolite PANOMIX_OTCML-2023 blood metabolite natural product


代谢物信息卡片


[3-({6-[(benzoyloxy)methyl]-3,4,5-trihydroxyoxan-2-yl}oxy)-6-hydroxy-8-methyl-9,10-dioxatetracyclo[4.3.1.0²,⁵.0³,⁸]decan-2-yl]methyl benzoate

化学式: C30H32O12 (584.1893672)
中文名称: 苯甲酰芍药苷
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC12CC3(C4CC1(C4(C(O2)O3)COC(=O)C5=CC=CC=C5)OC6C(C(C(C(O6)COC(=O)C7=CC=CC=C7)O)O)O)O
InChI: InChI=1S/C30H32O12/c1-27-14-29(36)19-12-30(27,28(19,26(41-27)42-29)15-38-24(35)17-10-6-3-7-11-17)40-25-22(33)21(32)20(31)18(39-25)13-37-23(34)16-8-4-2-5-9-16/h2-11,18-22,25-26,31-33,36H,12-15H2,1H3

描述信息

Benzoylpaeoniflorin, a natural product from Chinese paeony root, has the potential for coronary heart disease by decreasing apoptosis.
Benzoylpaeoniflorin, a natural product from Chinese paeony root, has the potential for coronary heart disease by decreasing apoptosis.

同义名列表

5 个代谢物同义名

[3-({6-[(benzoyloxy)methyl]-3,4,5-trihydroxyoxan-2-yl}oxy)-6-hydroxy-8-methyl-9,10-dioxatetracyclo[4.3.1.0²,⁵.0³,⁸]decan-2-yl]methyl benzoate; [6-[[2-(Benzoyloxymethyl)-6-hydroxy-8-methyl-9,10-dioxatetracyclo[4.3.1.02,5.03,8]decan-3-yl]oxy]-3,4,5-trihydroxyoxan-2-yl]methyl benzoate; 4-O-benzoylpaeoniflorin; 2-O-benzoylpaeoniflorin; Benzoylpaeoniflorin



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yajuan Bi, Xue Wang, Lifeng Han, Yiqing Tian, Tongwei Bo, Caiyu Li, Bowen Shi, Chunshan Gui, Youcai Zhang. Selective Inhibition of Organic Cation Transporter 1 by Benzoylpaeoniflorin Attenuates Hepatic Lipid Accumulation through AMPK Activation. Journal of natural products. 2023 01; 86(1):191-198. doi: 10.1021/acs.jnatprod.2c00927. [PMID: 36563333]
  • Chaeyeong Kim, Hyunchae Sim, Jong-Sup Bae. Benzoylpaeoniflorin Activates Anti-Inflammatory Mechanisms to Mitigate Sepsis in Cell-Culture and Mouse Sepsis Models. International journal of molecular sciences. 2022 Oct; 23(21):. doi: 10.3390/ijms232113130. [PMID: 36361915]
  • Wan-Chao Zhong, En-Can Li, Rui-Rui Hao, Jing-Fang Zhang, Hong-Tao Jin, Sheng Lin. Anti-anaphylactic potential of benzoylpaeoniflorin through inhibiting HDC and MAPKs from Paeonia lactiflora. Chinese journal of natural medicines. 2021 Nov; 19(11):825-835. doi: 10.1016/s1875-5364(21)60086-9. [PMID: 34844721]
  • Lihua Zuo, Zhi Sun, Zhenhui Wang, Daling Ding, Tanye Xu, Liwei Liu, Li Gao, Shuzhang Du, Jian Kang, Xiaojian Zhang. Tissue distribution profiles of multiple major bioactive components in rats after intravenous administration of Xuebijing injection by UHPLC-Q-Orbitrap HRMS. Biomedical chromatography : BMC. 2019 Feb; 33(2):e4400. doi: 10.1002/bmc.4400. [PMID: 30255561]
  • Yan-Hong Shi, Shu Zhu, Yue-Wei Ge, Kazufumi Toume, Zhengtao Wang, Javzan Batkhuu, Katsuko Komatsu. Characterization and quantification of monoterpenoids in different types of peony root and the related Paeonia species by liquid chromatography coupled with ion trap and time-of-flight mass spectrometry. Journal of pharmaceutical and biomedical analysis. 2016 Sep; 129(?):581-592. doi: 10.1016/j.jpba.2016.07.031. [PMID: 27521818]
  • Chu Chu, Shidi Zhang, Shengqiang Tong, Xingnuo Li, Qingyong Li, Jizhong Yan. Elution-extrusion counter-current chromatography for the separation of two pairs of isomeric monoterpenes from Paeoniae Alba Radix. Journal of separation science. 2015 Sep; 38(17):3110-8. doi: 10.1002/jssc.201500409. [PMID: 26114881]
  • Shuyun Wang, Jian Huang, Huijuan Mao, Yuliang Wang, Rena Kasimu, Wei Xiao, Jinhui Wang. A novel method HPLC-DAD analysis of the Contentsof Moutan Cortexand Paeoniae Radix Alba with similar constituents-monoterpene glycosides in Guizhi Fuling Wan. Molecules (Basel, Switzerland). 2014 Nov; 19(11):17957-67. doi: 10.3390/molecules191117957. [PMID: 25375336]
  • Ming Kong, Huan-Huan Liu, Jun Xu, Chun-Ru Wang, Ming Lu, Xiao-Ning Wang, You-Bin Li, Song-Lin Li. Quantitative evaluation of Radix Paeoniae Alba sulfur-fumigated with different durations and purchased from herbal markets: simultaneous determination of twelve components belonging to three chemical types by improved high performance liquid chromatography-diode array detector. Journal of pharmaceutical and biomedical analysis. 2014 Sep; 98(?):424-33. doi: 10.1016/j.jpba.2014.06.027. [PMID: 25011060]
  • Xia Zhu, Ze-Hai Fang. New monoterpene glycosides from the root cortex of Paeonia suffruticosa and their potential anti-inflammatory activity. Natural product research. 2014; 28(5):301-5. doi: 10.1080/14786419.2013.858340. [PMID: 24236670]
  • Qiang Fu, Shu-Bin Wang, Shao-Hua Zhao, Xiao-Juan Chen, Peng-Fei Tu. Three new monoterpene glycosides from the roots of Paeonia lactiflora. Journal of Asian natural products research. 2013 Jul; 15(7):697-702. doi: 10.1080/10286020.2013.794420. [PMID: 23659613]
  • Mo-Lian Ren, Xue Zhang, Rong Ding, Yi Dai, Feng-Juan Tu, Yi-Yu Cheng, Xin-Sheng Yao. Two new monoterpene glucosides from Paeonia lactiflora Pall. Journal of Asian natural products research. 2009 Jul; 11(7):670-4. doi: 10.1080/10286020902980087. [PMID: 20183305]
  • Alessandra Braca, Phan Van Kiem, Pham Hai Yen, Nguyen Xuan Nhiem, Tran Hong Quang, Nguyen Xuan Cuong, Chau Van Minh. New monoterpene glycosides from Paeonia lactiflora. Fitoterapia. 2008 Feb; 79(2):117-20. doi: 10.1016/j.fitote.2007.11.001. [PMID: 18201840]
  • Pham Hai Yen, Phan Van Kiem, Nguyen Xuan Nhiem, Nguyen Huu Tung, Tran Hong Quang, Chau Van Minh, Jung Woo Kim, Eun Mi Choi, Young Ho Kim. A new monoterpene glycoside from the roots of Paeonia lactiflora increases the differentiation of osteoblastic MC3T3-E1 cells. Archives of pharmacal research. 2007 Oct; 30(10):1179-85. doi: 10.1007/bf02980258. [PMID: 18038896]
  • Lianyu Guo, So Yean Cho, Sam Sik Kang, Seung-Ho Lee, Hum-Young Baek, Yeong Shik Kim. Orthogonal array design for optimizing extraction efficiency of active constituents from Jakyak-Gamcho Decoction, the complex formula of herbal medicines, Paeoniae Radix and Glycyrrhizae Radix. Journal of ethnopharmacology. 2007 Sep; 113(2):306-11. doi: 10.1016/j.jep.2007.06.013. [PMID: 17681441]
  • Qing He, Xing-Jiang Hu, Yi-Yu Cheng. Analysis of 'SHUANGDAN' granules by high-performance liquid chromatography-diode array detection-electrospray ionization tandem mass spectrometry. Journal of pharmaceutical and biomedical analysis. 2006 May; 41(2):485-92. doi: 10.1016/j.jpba.2006.01.010. [PMID: 16504448]
  • C F Wu. [A review on the pharmacology of Paeonia lactiflora and its chemical components]. Zhong yao tong bao (Beijing, China : 1981). 1985 Jun; 10(6):43-5. doi: ". [PMID: 2934174]