Benzidine, tetramethyl- (BioDeep_00000176533)
human metabolite blood metabolite
代谢物信息卡片
2,3,5,6-tetramethyl-[1,1-biphenyl]-4,4-diamine
化学式: C16H20N2 (240.16264)
中文名称:
谱图信息:
最多检出来源 Danio rerio(blood) 2.63%
分子结构信息
SMILES: CC1=C(C(=C(C(=C1C2=CC=C(C=C2)N)C)C)N)C
InChI: InChI=1S/C16H20N2/c1-9-11(3)16(18)12(4)10(2)15(9)13-5-7-14(17)8-6-13/h5-8H,17-18H2,1-4H3
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Pedro Nadal, Alessandro Pinto, Marketa Svobodova, Nuria Canela, Ciara K O'Sullivan. DNA aptamers against the Lup an 1 food allergen.
PloS one.
2012; 7(4):e35253. doi:
10.1371/journal.pone.0035253. [PMID: 22529997] - Tomoko Konno, Saori Hata, Yukiko Hamada, Yuko Horikoshi-Sakuraba, Tadashi Nakaya, Yuhki Saito, Tohru Yamamoto, Takayuki Yamamoto, Masahiro Maeda, Takeshi Ikeuchi, Sam Gandy, Hiroyasu Akatsu, Toshiharu Suzuki. Coordinated increase of γ-secretase reaction products in the plasma of some female Japanese sporadic Alzheimer's disease patients: quantitative analysis of p3-Alcα with a new ELISA system.
Molecular neurodegeneration.
2011 Nov; 6(?):76. doi:
10.1186/1750-1326-6-76. [PMID: 22067061] - Mi Kyung Park, Min Kyoung Cho, Shin Ae Kang, Hye-Kyung Park, Yun Seong Kim, Ki Uk Kim, Soon Cheol Ahn, Dong-Hee Kim, Hak Sun Yu. Protease-activated receptor 2 is involved in Th2 responses against Trichinella spiralis infection.
The Korean journal of parasitology.
2011 Sep; 49(3):235-43. doi:
10.3347/kjp.2011.49.3.235. [PMID: 22072823] - Gehan Ahmed Mostafa, Laila Yousef Al-Ayadhi. A lack of association between hyperserotonemia and the increased frequency of serum anti-myelin basic protein auto-antibodies in autistic children.
Journal of neuroinflammation.
2011 Jun; 8(?):71. doi:
10.1186/1742-2094-8-71. [PMID: 21696608] - Mathews Lisa, Nagaraja Haleagrahara, Srikumar Chakravarthi. Insulin-Like Growth Factor-1 (IGF-1) Reduces ischemic changes and increases circulating angiogenic factors in experimentally - induced myocardial infarction in rats.
Vascular cell.
2011 Jun; 3(1):13. doi:
10.1186/2045-824x-3-13. [PMID: 21651821] - Rafik Bachoual, Wifak Talmoudi, Tarek Boussetta, Françoise Braut, Jamel El-Benna. An aqueous pomegranate peel extract inhibits neutrophil myeloperoxidase in vitro and attenuates lung inflammation in mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2011 Jun; 49(6):1224-8. doi:
10.1016/j.fct.2011.02.024. [PMID: 21376769] - Kinga Csorba, Sabine Schmidt, Florina Florea, Norito Ishii, Takashi Hashimoto, Michael Hertl, Sarolta Kárpáti, Leena Bruckner-Tuderman, Wataru Nishie, Cassian Sitaru. Development of an ELISA for sensitive and specific detection of IgA autoantibodies against BP180 in pemphigoid diseases.
Orphanet journal of rare diseases.
2011 May; 6(?):31. doi:
10.1186/1750-1172-6-31. [PMID: 21619684] - Sally J Everest, Andrew M Ramsay, Melanie J Chaplin, Sharon Everitt, Michael J Stack, Michael H Neale, Martin Jeffrey, S Jo Moore, Susan J Bellworthy, Linda A Terry. Detection and localisation of PrP(Sc) in the liver of sheep infected with scrapie and bovine spongiform encephalopathy.
PloS one.
2011 May; 6(5):e19737. doi:
10.1371/journal.pone.0019737. [PMID: 21589864] - Katarína Bauerová, Silvester Poništ, Danica Mihalová, František Dráfi, Viera Kuncírová. Utilization of adjuvant arthritis model for evaluation of new approaches in rheumatoid arthritis therapy focused on regulation of immune processes and oxidative stress.
Interdisciplinary toxicology.
2011 Mar; 4(1):33-9. doi:
10.2478/v10102-011-0007-9. [PMID: 21577282] - Wei Wang, Jinming Li. Identification of natural bispecific antibodies against cyclic citrullinated peptide and immunoglobulin G in rheumatoid arthritis.
PloS one.
2011 Jan; 6(1):e16527. doi:
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Arthritis research & therapy.
2011; 13(6):R201. doi:
10.1186/ar3534. [PMID: 22152684] - Xinhui Li, Kory R Johnson, Mark Bryant, Abdel G Elkahloun, Marcelo Amar, Alan T Remaley, Ranil De Silva, John M Hallenbeck, Jacqueline A Quandt. Intranasal delivery of E-selectin reduces atherosclerosis in ApoE-/- mice.
PloS one.
2011; 6(6):e20620. doi:
10.1371/journal.pone.0020620. [PMID: 21701687] - Hongtao Zhang, Ting Fu, Suzanne McGettigan, Suresh Kumar, Shujing Liu, David Speicher, Lynn Schuchter, Xiaowei Xu. IL-8 and cathepsin B as melanoma serum biomarkers.
International journal of molecular sciences.
2011; 12(3):1505-18. doi:
10.3390/ijms12031505. [PMID: 21673904] - Matheus Correa-Costa, Tarcio Teodoro Braga, Patricia Semedo, Caroline Yuri Hayashida, Luiz Roberto Grassmann Bechara, Rosa Maria Elias, Claudiene Rodrigues Barreto, Claudia Silva-Cunha, Meire Ioshie Hyane, Giselle Martins Gonçalves, Patricia Chakur Brum, Clarice Fujihara, Roberto Zatz, Alvaro Pacheco-Silva, Dario S Zamboni, Niels Olsen Saraiva Camara. Pivotal role of Toll-like receptors 2 and 4, its adaptor molecule MyD88, and inflammasome complex in experimental tubule-interstitial nephritis.
PloS one.
2011; 6(12):e29004. doi:
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Evidence-based complementary and alternative medicine : eCAM.
2011; 2011(?):146808. doi:
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PloS one.
2011; 6(10):e25697. doi:
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Cardiovascular diabetology.
2010 Oct; 9(?):70. doi:
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Vox sanguinis.
2010 Oct; 99(3):220-31. doi:
10.1111/j.1423-0410.2010.01345.x. [PMID: 20840337] - Marija Pinne, Henry A Choy, David A Haake. The OmpL37 surface-exposed protein is expressed by pathogenic Leptospira during infection and binds skin and vascular elastin.
PLoS neglected tropical diseases.
2010 Sep; 4(9):e815. doi:
10.1371/journal.pntd.0000815. [PMID: 20844573] - Carmen Calinescu, Rodolfo Federico, Bruno Mondovi, Mircea Alexandru Mateescu. Zymographic assay of plant diamine oxidase on entrapped peroxidase polyacrylamide gel electrophoresis. A study of stability to proteolysis.
Analytical and bioanalytical chemistry.
2010 Feb; 396(3):1281-90. doi:
10.1007/s00216-009-3306-7. [PMID: 20091155] - In-Ah Lee, Eun-Ah Bae, Yang-Jin Hyun, Dong-Hyun Kim. Dextran sulfate sodium and 2,4,6-trinitrobenzene sulfonic acid induce lipid peroxidation by the proliferation of intestinal gram-negative bacteria in mice.
Journal of inflammation (London, England).
2010 Feb; 7(?):7. doi:
10.1186/1476-9255-7-7. [PMID: 20181058] - ZhenZhen Zhao, Wei Liu, Yuxi Su, Jin Zhu, GaiHuan Zheng, Qing Luo, XianQing Jin. Evaluation of biodistribution and safety of adenovirus vector containing MDR1 in mice.
Journal of experimental & clinical cancer research : CR.
2010 Jan; 29(?):1. doi:
10.1186/1756-9966-29-1. [PMID: 20044941] - Hong Jiang, Wenqing Chen, Lihui Qu, Ying Chen, Qiang He, Huiping Wang, Jianyong Wu, Zhangfei Shou, Zhenyu Ju, Jianghua Chen. ELISA for aging biomarkers induced by telomere dysfunction in human plasma.
Journal of biomedicine & biotechnology.
2010; 2010(?):121947. doi:
10.1155/2010/121947. [PMID: 21127712] - Ayman A Yousef, Ghada A Suliman, Maaly M Mabrouk. The value of correlation of serum 20S proteasome concentration and percentage of lymphocytic apoptosis in critically ill patients: a prospective observational study.
Critical care (London, England).
2010; 14(6):R215. doi:
10.1186/cc9340. [PMID: 21108816] - Declan Madsen, Emma R Cantwell, Timothy O'Brien, Patricia A Johnson, Bernard P Mahon. Adeno-associated virus serotype 2 induces cell-mediated immune responses directed against multiple epitopes of the capsid protein VP1.
The Journal of general virology.
2009 Nov; 90(Pt 11):2622-2633. doi:
10.1099/vir.0.014175-0. [PMID: 19641045] - Richa Tripathi, Gayatri Rath, Ranju Ralhan, Sunita Saxena, Sudha Salhan. Soluble and membranous vascular endothelial growth factor receptor-2 in pregnancies complicated by pre-eclampsia.
Yonsei medical journal.
2009 Oct; 50(5):656-66. doi:
10.3349/ymj.2009.50.5.656. [PMID: 19881969] - Rosalind A Rosenthal, Karl D Huffman, Leslie W Fisette, Christy A Damphousse, Wyeth B Callaway, Bernard Malfroy, Susan R Doctrow. Orally available Mn porphyrins with superoxide dismutase and catalase activities.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry.
2009 Aug; 14(6):979-91. doi:
10.1007/s00775-009-0550-4. [PMID: 19504132] - Irene Paterniti, Tiziana Genovese, Concetta Crisafulli, Emanuela Mazzon, Rosanna Di Paola, Maria Galuppo, Placido Bramanti, Salvatore Cuzzocrea. Treatment with green tea extract attenuates secondary inflammatory response in an experimental model of spinal cord trauma.
Naunyn-Schmiedeberg's archives of pharmacology.
2009 Aug; 380(2):179-92. doi:
10.1007/s00210-009-0414-z. [PMID: 19337722] - Nang L Nguyen, Binh Minh Le, David Wang. Serologic evidence of frequent human infection with WU and KI polyomaviruses.
Emerging infectious diseases.
2009 Aug; 15(8):1199-205. doi:
10.3201/eid1508.090270. [PMID: 19751580] - Hamid A Kazi, Zhiyu Qian. Crocetin reduces TNBS-induced experimental colitis in mice by downregulation of NFkB.
Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association.
2009 Jul; 15(3):181-7. doi:
10.4103/1319-3767.54750. [PMID: 19636180] - Vasiliki Koliaraki, Martha Marinou, Theodoros P Vassilakopoulos, Eustathios Vavourakis, Emmanuel Tsochatzis, Gerassimos A Pangalis, George Papatheodoridis, Alexandra Stamoulakatou, Dorine W Swinkels, George Papanikolaou, Avgi Mamalaki. A novel immunological assay for hepcidin quantification in human serum.
PloS one.
2009; 4(2):e4581. doi:
10.1371/journal.pone.0004581. [PMID: 19238200] - Valerie Wells, Livio Mallucci. Phosphoinositide 3-kinase targeting by the beta galactoside binding protein cytokine negates akt gene expression and leads aggressive breast cancer cells to apoptotic death.
Breast cancer research : BCR.
2009; 11(1):R2. doi:
10.1186/bcr2217. [PMID: 19133120] - Driss Mountassif, Pierre Andreoletti, Zakaria El Kebbaj, Adnane Moutaouakkil, Mustapha Cherkaoui-Malki, Norbert Latruffe, M'hammed Saïd El Kebbaj. Immunoaffinity purification and characterization of mitochondrial membrane-bound D-3-hydroxybutyrate dehydrogenase from Jaculus orientalis.
BMC biochemistry.
2008 Sep; 9(?):26. doi:
10.1186/1471-2091-9-26. [PMID: 18826626] - Byong-Su Jang, Hyeran Kim, Shinn-Won Lim, Ki-Won Jang, Doh-Kwan Kim. Serum S100B Levels and Major Depressive Disorder: Its Characteristics and Role in Antidepressant Response.
Psychiatry investigation.
2008 Sep; 5(3):193-8. doi:
10.4306/pi.2008.5.3.193. [PMID: 20046365] - Udai P Singh, Rajesh Singh, Shailesh Singh, Russell K Karls, Frederick D Quinn, Dennis D Taub, James W Lillard. CXCL10+ T cells and NK cells assist in the recruitment and activation of CXCR3+ and CXCL11+ leukocytes during Mycobacteria-enhanced colitis.
BMC immunology.
2008 Jun; 9(?):25. doi:
10.1186/1471-2172-9-25. [PMID: 18533024] - John-Helge Heimdal, Kenneth Kross, Beate Klementsen, Jan Olofsson, Hans Jørgen Aarstad. Stimulated monocyte IL-6 secretion predicts survival of patients with head and neck squamous cell carcinoma.
BMC cancer.
2008 Jan; 8(?):34. doi:
10.1186/1471-2407-8-34. [PMID: 18234094] - Ulrich Baumann, Kerstin Göcke, Britta Gewecke, Joachim Freihorst, Bernd Ulrich von Specht. Assessment of pulmonary antibodies with induced sputum and bronchoalveolar lavage induced by nasal vaccination against Pseudomonas aeruginosa: a clinical phase I/II study.
Respiratory research.
2007 Aug; 8(?):57. doi:
10.1186/1465-9921-8-57. [PMID: 17683588] - R B Sawant, S K Jathar, S B Rajadhyaksha, P T Kadam. Red cell hemolysis during processing and storage.
Asian journal of transfusion science.
2007 Jul; 1(2):47-51. doi:
10.4103/0973-6247.33446. [PMID: 21938232] - Brajesh C Varshney, N M Ponnanna, Pranati A Sarkar, Pragna Rehman, Jigar H Shah. Development of a monoclonal antibody-based co-agglutination test to detect enterotoxigenic Escherichia coli isolated from diarrheic neonatal calves.
Journal of veterinary science.
2007 Mar; 8(1):57-64. doi:
10.4142/jvs.2007.8.1.57. [PMID: 17322775] - Hao-Chih Tai, Nathalie Campanile, Mohamed Ezzelarab, David K C Cooper, Carol Phelps. Measurement of anti-CD154 monoclonal antibody in primate sera by competitive inhibition ELISA.
Xenotransplantation.
2006 Nov; 13(6):566-70. doi:
10.1111/j.1399-3089.2006.00345.x. [PMID: 17059584] - Eva Jiménez-Medina, Angel Garcia-Lora, Laura Paco, Ignacio Algarra, Antonia Collado, Federico Garrido. A new extract of the plant Calendula officinalis produces a dual in vitro effect: cytotoxic anti-tumor activity and lymphocyte activation.
BMC cancer.
2006 May; 6(?):119. doi:
10.1186/1471-2407-6-119. [PMID: 16677386] - Klabusay Martin, Kohutova Viera, Coupek Petr, Nenickova Marie, Tesarova Eva. Simultaneous analysis of cytokines and co-stimulatory molecules concentrations by ELISA technique and of probabilities of measurable concentrations of interleukins IL-2, IL-4, IL-5, IL-6, CXCL8 (IL-8), IL-10, IL-13 occurring in plasma of healthy blood donors.
Mediators of inflammation.
2006; 2006(5):65237. doi:
10.1155/mi/2006/65237. [PMID: 17392576] - Tarja Sorsa-Leslie, Helen D Mason, William J Harris, Paul A Fowler. Selection of gonadotrophin surge attenuating factor phage antibodies by bioassay.
Reproductive biology and endocrinology : RB&E.
2005 Sep; 3(?):49. doi:
10.1186/1477-7827-3-49. [PMID: 16185358] - Mojtaba Sankian, Abdolreza Varasteh, Nazanin Pazouki, Mahmoud Mahmoudi. Sequence homology: a poor predictive value for profilins cross-reactivity.
Clinical and molecular allergy : CMA.
2005 Sep; 3(?):13. doi:
10.1186/1476-7961-3-13. [PMID: 16153305] - Arjen M Dondorp, Varunee Desakorn, Wirichada Pongtavornpinyo, Duangjai Sahassananda, Kamolrat Silamut, Kesinee Chotivanich, Paul N Newton, Punnee Pitisuttithum, A M Smithyman, Nicholas J White, Nicholas P J Day. Estimation of the total parasite biomass in acute falciparum malaria from plasma PfHRP2.
PLoS medicine.
2005 Aug; 2(8):e204. doi:
10.1371/journal.pmed.0020204. [PMID: 16104831] - Rosanna Di Paola, Emanuela Mazzon, Carmelo Muià, Tiziana Genovese, Marta Menegazzi, Raffaela Zaffini, Hisanory Suzuki, Salvatore Cuzzocrea. Green tea polyphenol extract attenuates lung injury in experimental model of carrageenan-induced pleurisy in mice.
Respiratory research.
2005 Jun; 6(?):66. doi:
10.1186/1465-9921-6-66. [PMID: 15987519] - Lixin Xie, Youning Liu, Baoxing Fan, Yueyong Xiao, Qing Tian, Liangan Chen, Hong Zhao, Weijun Chen. Dynamic changes of serum SARS-coronavirus IgG, pulmonary function and radiography in patients recovering from SARS after hospital discharge.
Respiratory research.
2005 Jan; 6(?):5. doi:
10.1186/1465-9921-6-5. [PMID: 15638943] - Martin Skoumal, Günther Haberhauer, Gernot Kolarz, Gerhard Hawa, Wolfgang Woloszczuk, Anton Klingler. Serum cathepsin K levels of patients with longstanding rheumatoid arthritis: correlation with radiological destruction.
Arthritis research & therapy.
2005; 7(1):R65-70. doi:
10.1186/ar1461. [PMID: 15642144] - Guodong Liang, Qiuxia Chen, Jianguo Xu, Yufei Liu, Wilina Lim, J S M Peiris, Larry J Anderson, Li Ruan, Hui Li, Biao Kan, Biao Di, Peter Cheng, K H Chan, Dean D Erdman, Shuyan Gu, Xinge Yan, Weili Liang, Duanhua Zhou, Lia Haynes, Shumin Duan, Xin Zhang, Han Zheng, Yang Gao, Suxiang Tong, Dexin Li, Ling Fang, Pengzhe Qin, Wenbo Xu. Laboratory diagnosis of four recent sporadic cases of community-acquired SARS, Guangdong Province, China.
Emerging infectious diseases.
2004 Oct; 10(10):1774-81. doi:
10.3201/eid1010.040445. [PMID: 15504263] - A Yao, M Harada, S Matsueda, Y Ishihara, H Shomura, M Noguchi, K Matsuoka, I Hara, S Kamidono, K Itoh. Identification of parathyroid hormone-related protein-derived peptides immunogenic in human histocompatibility leukocyte antigen-A24+ prostate cancer patients.
British journal of cancer.
2004 Jul; 91(2):287-96. doi:
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Transfusion.
2004 Jul; 44(7):984-9. doi:
10.1111/j.1537-2995.2004.03315.x. [PMID: 15225237] - Bernhard Manz, Matthias Kuper, Essy Booltink, Ulrich Fischer-Brügge. Development of enantioselective immunoassays for free plasma metanephrines.
Annals of the New York Academy of Sciences.
2004 Jun; 1018(?):582-7. doi:
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Journal of pharmacological and toxicological methods.
2002 May; 47(3):169-75. doi:
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