Benzenesulfonamide (BioDeep_00000176528)
human metabolite blood metabolite
代谢物信息卡片
Benzenesulfonamide monosodium salt
化学式: C6H7NO2S (157.0197482)
中文名称: 苯磺酰胺
谱图信息:
最多检出来源 Homo sapiens(blood) 90%
分子结构信息
SMILES: C1=CC=C(C=C1)S(=O)(=O)N
InChI: InChI=1S/C6H7NO2S/c7-10(8,9)6-4-2-1-3-5-6/h1-5H,(H2,7,8,9)
描述信息
D004791 - Enzyme Inhibitors > D002257 - Carbonic Anhydrase Inhibitors
同义名列表
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Ahmed M El-Saghier, Souhaila S Enaili, Aly Abdou, Abdullah Y A Alzahrani, Sana Ben Moussa, Mohamed A Gad, Asmaa M Kadry. Thiadiazole/Thiadiazine Derivatives as Insecticidal Agent: Design, Synthesis, and Biological Assessment of 1,3,4-(Thiadiazine/Thiadiazole)-Benzenesulfonamide Derivatives as IGRs Analogues against Spodoptera littoralis.
Journal of agricultural and food chemistry.
2024 May; 72(20):11369-11380. doi:
10.1021/acs.jafc.3c09703. [PMID: 38727083] - Ye-Rang Yun, Ji-Eun Lee. Kimchi attenuates endoplasmic reticulum stress-induced hepatic steatosis in HepG2 cells and C57BL/6N mice.
Nutrition research (New York, N.Y.).
2024 Apr; 124(?):43-54. doi:
10.1016/j.nutres.2024.01.013. [PMID: 38367426] - Monika, Chander, Deepansh Sharma, Pawan K Sharma, Sita Ram. Synthesis and biological evaluation of novel benzenesulfonamide incorporated thiazole-triazole hybrids as antimicrobial and antioxidant agents.
Archiv der Pharmazie.
2024 Mar; 357(3):e2300650. doi:
10.1002/ardp.202300650. [PMID: 38154111] - Dong-Ping Wang, Meng Zhang, Ming Li, Xiao-Na Yang, Changzhu Li, Peng Cao, Michael X Zhu, Yun Tian, Ye Yu, Yun-Tao Lei. Druggable site near the upper vestibule determines the high affinity and P2X3 homotrimer selectivity of Sivopixant/S-600918 and its analogue DDTPA.
British journal of pharmacology.
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Chemico-biological interactions.
2023 Mar; 373(?):110381. doi:
10.1016/j.cbi.2023.110381. [PMID: 36746201] - Óscar Castro, Sílvia Borrull, Eva Pocurull, Francesc Borrull. Determination of benzothiazoles, benzotriazoles and benzenesulfonamides in seafood using quick, easy, cheap, effective, rugged and safe extraction followed by gas chromatography - tandem mass spectrometry: Method development and risk assessment.
Journal of chromatography. A.
2023 Feb; 1691(?):463841. doi:
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ChemMedChem.
2022 02; 17(4):e202100507. doi:
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Journal of medicinal chemistry.
2020 03; 63(5):2114-2130. doi:
10.1021/acs.jmedchem.9b00664. [PMID: 31244114] - Chul Soon Park, Kazuki Iwabata, Uma Sridhar, Michael Tsuei, Khushboo Singh, Young-Ki Kim, S Thayumanavan, Nicholas L Abbott. A New Strategy for Reporting Specific Protein Binding Events at Aqueous-Liquid Crystal Interfaces in the Presence of Non-Specific Proteins.
ACS applied materials & interfaces.
2020 Feb; 12(7):7869-7878. doi:
10.1021/acsami.9b16867. [PMID: 31825195] - Sun-Yee Cheung, Markus Werner, Lucia Esposito, Fabiana Troisi, Vincenza Cantone, Stefanie Liening, Stefanie König, Jana Gerstmeier, Andreas Koeberle, Rossella Bilancia, Roberta Rizza, Antonietta Rossi, Fiorentina Roviezzo, Veronika Temml, Daniela Schuster, Hermann Stuppner, Manfred Schubert-Zsilavecz, Oliver Werz, Thomas Hanke, Simona Pace. Discovery of a benzenesulfonamide-based dual inhibitor of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase that favorably modulates lipid mediator biosynthesis in inflammation.
European journal of medicinal chemistry.
2018 Aug; 156(?):815-830. doi:
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Pest management science.
2018 Jan; 74(1):189-199. doi:
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Prostaglandins & other lipid mediators.
2016 09; 125(?):40-7. doi:
10.1016/j.prostaglandins.2016.07.003. [PMID: 27432695] - Akinranti Ajibola, Pablo Gago-Ferrero, Viola L Borova, Marilena E Dasenaki, Anna A Bletsou, Nikolaos S Thomaidis. Benzosulfonamides in wastewater: method development, occurrence and removal efficiencies.
Chemosphere.
2015 Jan; 119 Suppl(?):S21-7. doi:
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Bioorganic & medicinal chemistry letters.
2014 Jul; 24(14):3064-8. doi:
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PloS one.
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Analytical and bioanalytical chemistry.
2011 Jun; 400(6):1653-64. doi:
10.1007/s00216-011-4905-7. [PMID: 21461620] - Polyxeni Alexiou, Vassilis J Demopoulos. A diverse series of substituted benzenesulfonamides as aldose reductase inhibitors with antioxidant activity: design, synthesis, and in vitro activity.
Journal of medicinal chemistry.
2010 Nov; 53(21):7756-66. doi:
10.1021/jm101008m. [PMID: 20936791] - Jeffrey G Varnes, Janet M Forst, Tiffany N Hoerter, Christopher R Holmquist, Deidre E Wilkins, Gaochao Tian, Gerald Jonak, Xia Wang, William M Potts, Michael W Wood, Cristóbal Alhambra, Todd A Brugel, Jeffrey S Albert. Identification of N-(2-(azepan-1-yl)-2-phenylethyl)-benzenesulfonamides as novel inhibitors of GlyT1.
Bioorganic & medicinal chemistry letters.
2010 Aug; 20(16):4878-81. doi:
10.1016/j.bmcl.2010.06.085. [PMID: 20637614] - Naresh Kumar, Laura A Solt, Juliana J Conkright, Yongjun Wang, Monica A Istrate, Scott A Busby, Ruben D Garcia-Ordonez, Thomas P Burris, Patrick R Griffin. The benzenesulfoamide T0901317 [N-(2,2,2-trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzenesulfonamide] is a novel retinoic acid receptor-related orphan receptor-alpha/gamma inverse agonist.
Molecular pharmacology.
2010 Feb; 77(2):228-36. doi:
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Journal of contaminant hydrology.
2009 May; 106(3-4):183-94. doi:
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2009 Mar; 19(6):1740-4. doi:
10.1016/j.bmcl.2009.01.082. [PMID: 19216076] - Hermenegilda Moreno-Díaz, Rafael Villalobos-Molina, Rolffy Ortiz-Andrade, Daniel Díaz-Coutiño, Jose Luis Medina-Franco, Scott P Webster, Margaret Binnie, Samuel Estrada-Soto, Maximiliano Ibarra-Barajas, Ismael León-Rivera, Gabriel Navarrete-Vázquez. Antidiabetic activity of N-(6-substituted-1,3-benzothiazol-2-yl)benzenesulfonamides.
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Pest management science.
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