benserazide (BioDeep_00000176514)
human metabolite blood metabolite
代谢物信息卡片
2-amino-3-hydroxy-N-[(2,3,4-trihydroxyphenyl)methyl]propanehydrazonic acid
化学式: C10H15N3O5 (257.101166)
中文名称: 苄丝肼
谱图信息:
最多检出来源 Homo sapiens(blood) 66.67%
分子结构信息
SMILES: C1=CC(=C(C(=C1CNNC(=O)C(CO)N)O)O)O
InChI: InChI=1S/C10H15N3O5/c11-6(4-14)10(18)13-12-3-5-1-2-7(15)9(17)8(5)16/h1-2,6,12,14-17H,3-4,11H2,(H,13,18)
描述信息
D002491 - Central Nervous System Agents > D018726 - Anti-Dyskinesia Agents > D000978 - Antiparkinson Agents
C78272 - Agent Affecting Nervous System > C38149 - Antiparkinsonian Agent
D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents
D004791 - Enzyme Inhibitors
C471 - Enzyme Inhibitor
同义名列表
14 个代谢物同义名
2-amino-3-hydroxy-N-[(2,3,4-trihydroxyphenyl)methyl]propanehydrazonic acid; 2-Amino-3-hydroxy-2-(2,3,4-trihydroxybenzyl)propionohydrazide; DL-Serine 2-[(2,3,4-trihydroxyphenyl)methyl]hydrazide; DL-Serine 2-((2,3,4-trihydroxyphenyl)methyl)hydrazide; DL-Serine 2-(2,3,4-trihydroxybenzyl)hydrazide; Benzylhydrazine, seryltrihydroxy; Seryltrihydroxy benzylhydrazine; Seryltrihydroxybenzylhydrazine; Benserazidum; Benserazida; benserazide; Ro 4-4602; Ro 44602; Serazide
数据库引用编号
10 个数据库交叉引用编号
- ChEBI: CHEBI:64187
- PubChem: 2327
- HMDB: HMDB0248960
- DrugBank: DB12783
- ChEMBL: CHEMBL1096979
- Wikipedia: Benserazide
- MeSH: Benserazide
- chemspider: 2237
- CAS: 322-35-0
- RefMet: Benserazide
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- De-Qi Jiang, Qing-Min Zang, Li-Lin Jiang, Yan Wang, Ming-Xing Li, Jing-Yi Qiao. Comparison of pramipexole and levodopa/benserazide combination therapy versus levodopa/benserazide monotherapy in the treatment of Parkinson's disease: a systematic review and meta-analysis.
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Journal of clinical pharmacy and therapeutics.
2009 Jun; 34(3):345-54. doi:
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Psychopharmacology.
2009 Jun; 204(2):241-50. doi:
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Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.
2009 Apr; 15(3):275-6. doi:
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The International journal of neuroscience.
2009; 119(8):1190-7. doi:
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2008 Dec; 28(4):255-7. doi:
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Brain : a journal of neurology.
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International journal of pharmaceutics.
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2008 Oct; 6(10):1024-8. doi:
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European journal of clinical pharmacology.
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Synapse (New York, N.Y.).
2008 Aug; 62(8):632-5. doi:
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Journal of neural transmission (Vienna, Austria : 1996).
2008 Jun; 115(6):851-5. doi:
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Behavioural brain research.
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Molecules (Basel, Switzerland).
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Current clinical pharmacology.
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Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.
2007 Sep; 27(9):796-9. doi:
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Neuroscience letters.
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2007 Jan; 43(2):774-8. doi:
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2006 Sep; 253(9):1221-6. doi:
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Kidney & blood pressure research.
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Clinical neuropharmacology.
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Movement disorders : official journal of the Movement Disorder Society.
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American journal of physiology. Renal physiology.
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Neuroscience letters.
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European journal of clinical pharmacology.
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Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology.
2003 Oct; 24(3):192-3. doi:
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Life sciences.
2003 Sep; 73(18):2335-44. doi:
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European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
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European neurology.
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Neuropharmacology.
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No to shinkei = Brain and nerve.
2002 Feb; 54(2):127-32. doi:
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Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia.
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Clinical pharmacokinetics.
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Brain research.
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