Azoxymethane (BioDeep_00000176390)
human metabolite blood metabolite
代谢物信息卡片
methyl(methyl-oxo-λ⁵-azanylidene)amine
化学式: C2H6N2O (74.048)
中文名称: 氧化偶氮甲烷
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CN=[N+](C)[O-]
InChI: InChI=1S/C2H6N2O/c1-3-4(2)5/h1-2H3
描述信息
D009676 - Noxae > D002273 - Carcinogens
同义名列表
数据库引用编号
7 个数据库交叉引用编号
- PubChem: 33184
- HMDB: HMDB0248817
- Wikipedia: Azoxymethane
- MeSH: Azoxymethane
- chemspider: 21242845
- CAS: 25843-45-2
- CAS: 54168-20-6
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- Huantian Cui, Yutong Jin, Ning Wang, Haizhao Liu, Rongli Shu, Jida Wang, Xiangling Wang, Beitian Jia, Yiyang Wang, Yuhong Bian, Weibo Wen. Mechanic evaluation of Wu-Mei-Pill on colitis-associated colorectal cancer: An integrated transcriptomics, metabolomics, and experimental validation study.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2024 Jun; 128(?):155509. doi:
10.1016/j.phymed.2024.155509. [PMID: 38452403] - Ke Cai, Xin-Yue Cao, Fan Chen, Yue Zhu, Dong-Dong Sun, Hai-Bo Cheng, Jin-Ao Duan, Shu-Lan Su. Xianlian Jiedu Decoction alleviates colorectal cancer by regulating metabolic profiles, intestinal microbiota and metabolites.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2024 Jun; 128(?):155385. doi:
10.1016/j.phymed.2024.155385. [PMID: 38569292] - Wenjing Zhao, Aiqi Ren, Shuhua Shan, Zhuoyu Li, Ruijun Su, Ruipeng Yang, Feihong Zhai, Lihua Wu, Zhaohui Tang, Jieya Yang, Linzhong Yue. Inhibitory Effects of Soluble Dietary Fiber from Foxtail Millet on Colorectal Cancer by the Restoration of Gut Microbiota.
Journal of agricultural and food chemistry.
2024 May; 72(21):12130-12145. doi:
10.1021/acs.jafc.4c00867. [PMID: 38748495] - Xiunan Wei, Junwei Liang, Jiahui Liu, Yonggang Dai, Xiaohui Leng, Yan Cheng, Lili Chi. Anchang Yuyang Decoction inhibits experimental colitis-related carcinogenesis by regulating PPAR signaling pathway and affecting metabolic homeostasis of host and microbiota.
Journal of ethnopharmacology.
2024 May; 326(?):117995. doi:
10.1016/j.jep.2024.117995. [PMID: 38428656] - Joanna Harasym, Katarzyna Dziendzikowska, Łukasz Kopiasz, Jacek Wilczak, Rafał Sapierzyński, Joanna Gromadzka-Ostrowska. Consumption of Feed Supplemented with Oat Beta-Glucan as a Chemopreventive Agent against Colon Cancerogenesis in Rats.
Nutrients.
2024 Apr; 16(8):. doi:
10.3390/nu16081125. [PMID: 38674816] - Yi-Fang Jiang, Yu-Qing Huang, Yan-E Hu, Yi Yang, Chuan Zheng, Feng-Ming You, Zi-Yi Zhao. [Banxia Xiexin Decoction inhibiting colitis-associated colorectal cancer infected with Fusobacterium nucleatum by regulating Wnt/β-catenin pathway].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2024 Mar; 49(5):1266-1274. doi:
10.19540/j.cnki.cjcmm.20231114.701. [PMID: 38621974] - Xiangli He, Jiayan Cui, Hui Ma, Naijipu Abuduaini, Ying Huang, Lu Tang, Wanyan Wang, Yuanyuan Zhang, Yang Wang, Weiqiang Lu, Bo Feng, Jin Huang. Berberrubine is a novel and selective IMPDH2 inhibitor that impairs the growth of colorectal cancer.
Biochemical pharmacology.
2023 Oct; 218(?):115868. doi:
10.1016/j.bcp.2023.115868. [PMID: 37871880] - Hongyan Gou, Hao Su, Dehua Liu, Chi Chun Wong, Haiyun Shang, Yi Fang, Xianyi Zeng, Huarong Chen, Yan Li, Ziheng Huang, Miao Fan, Chunxian Wei, Xin Wang, Xiang Zhang, Xiaoxing Li, Jun Yu. Traditional Medicine Pien Tze Huang Suppresses Colorectal Tumorigenesis through Restoring Gut Microbiota and Metabolites.
Gastroenterology.
2023 Sep; ?(?):. doi:
10.1053/j.gastro.2023.08.052. [PMID: 37704113] - Li-Mei Gu, He-Zhong Li, Lei Gao, Hui Li, Lan-Fu Wei, Cheng-Yu Pan, Ke-Xuan Wu, Yao-Zhou Tian. Huangqin Decoction Delays Progress of Colitis-Associated Carcinogenesis by Regulating Nrf2/HO-1 Antioxidant Signal Pathway in Mice.
Chinese journal of integrative medicine.
2023 Jul; ?(?):. doi:
10.1007/s11655-023-3554-y. [PMID: 37434030] - Ifeoma Julieth Dikeocha, Abdelkodose Mohammed Al-Kabsi, Ahmad Faheem Ahmeda, Michael Mathai, Mohammed Abdullah Alshawsh. Investigation into the Potential Role of Propionibacterium freudenreichii in Prevention of Colorectal Cancer and Its Effects on the Diversity of Gut Microbiota in Rats.
International journal of molecular sciences.
2023 Apr; 24(9):. doi:
10.3390/ijms24098080. [PMID: 37175785] - Ling Wang, Qing Qing Zhang, Yu Yu Xu, Rui Zhang, Qing Zhao, Yu-Qing Zhang, Xue-Hong Huang, Bin Jiang, Min Ni. Ginsenoside Rb1 Suppresses AOM/DSS-Induced Colon Carcinogenesis.
Anti-cancer agents in medicinal chemistry.
2023 Jan; ?(?):. doi:
10.2174/1871520623666230119092735. [PMID: 36655530] - Zhao-Xiu Liu, Wei-Jie Chen, Yang Wang, Bing-Qian Chen, Yi-Cun Liu, Tiao-Chun Cheng, Lei-Lei Luo, Lin Chen, Lin-Ling Ju, Yuan Liu, Ming Li, Nan Feng, Jian-Guo Shao, Zhao-Lian Bian. Interleukin-34 deficiency aggravates development of colitis and colitis-associated cancer in mice.
World journal of gastroenterology.
2022 Dec; 28(47):6752-6768. doi:
10.3748/wjg.v28.i47.6752. [PMID: 36620338] - Chuangen Li, Yong Wang, Dabin Liu, Chi Chun Wong, Olabisi Oluwabukola Coker, Xiang Zhang, Changan Liu, Yunfei Zhou, Yali Liu, Wei Kang, Ka Fai To, Joseph Jy Sung, Jun Yu. Squalene epoxidase drives cancer cell proliferation and promotes gut dysbiosis to accelerate colorectal carcinogenesis.
Gut.
2022 11; 71(11):2253-2265. doi:
10.1136/gutjnl-2021-325851. [PMID: 35232776] - J Liu, W Shen, H Cheng, M Fan, J Xiao, C Xu, J Tan, Y Lai, C Yu, D Sun, L Li. [Shenbai Jiedu Fang inhibits AOM/DSS-induced colorectal adenoma formation and carcinogenesis in mice via miRNA-22-mediated regulation of the PTEN/PI3K/AKT signaling pathway].
Nan fang yi ke da xue xue bao = Journal of Southern Medical University.
2022 Oct; 42(10):1452-1461. doi:
10.12122/j.issn.1673-4254.2022.10.03. [PMID: 36329578] - Haley A Chatelaine, Cynthia A Ramazani, Kyle Spencer, Susan Olivo-Marston, Michael T Bailey, Joseph McElroy, Emmanuel Hatzakis, Ewy A Mathé, Rachel E Kopec. Dietary Energy Intake and Presence of Aberrant Crypt Foci Are Associated with Phospholipid, Purine, and Taurine Metabolite Abundances in C57BL/6N Mouse Colon.
Molecular nutrition & food research.
2022 10; 66(20):e2200180. doi:
10.1002/mnfr.202200180. [PMID: 35969485] - Hongyan Lin, Xiaopeng Ma, Xiaorong Yang, Qingqing Chen, Zhongling Wen, Minkai Yang, Jiangyan Fu, Tongming Yin, Guihua Lu, Jinliang Qi, Hongwei Han, Yonghua Yang. Natural shikonin and acetyl-shikonin improve intestinal microbial and protein composition to alleviate colitis-associated colorectal cancer.
International immunopharmacology.
2022 Oct; 111(?):109097. doi:
10.1016/j.intimp.2022.109097. [PMID: 35952517] - Shengen Yi, Xiaoxin Jin, Bo Liu, Peidong Wu, Wang Xiao, Weidong Chen. Portulaca oleracea extract reduces gut microbiota imbalance and inhibits colorectal cancer progression via inactivation of the Wnt/β-catenin signaling pathway.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2022 Oct; 105(?):154279. doi:
10.1016/j.phymed.2022.154279. [PMID: 35963192] - Qiang Sun, Han Yang, Maolun Liu, Shan Ren, Hui Zhao, Tianqi Ming, Shun Tang, Qiu Tao, Li Chen, Sha Zeng, Dayue Darrel Duan, Haibo Xu. Berberine suppresses colorectal cancer by regulation of Hedgehog signaling pathway activity and gut microbiota.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2022 Aug; 103(?):154227. doi:
10.1016/j.phymed.2022.154227. [PMID: 35679795] - Shihai Yan, Jiayin Chang, Xuehui Hao, Jiang Liu, Xiying Tan, Zhirong Geng, Zhilin Wang. Berberine regulates short-chain fatty acid metabolism and alleviates the colitis-associated colorectal tumorigenesis through remodeling intestinal flora.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2022 Jul; 102(?):154217. doi:
10.1016/j.phymed.2022.154217. [PMID: 35660350] - Haitao Chen, Chenxiao Ye, Biyu Cai, Fan Zhang, Xuanying Wang, Jin Zhang, Zewei Zhang, Yong Guo, Qinghua Yao. Berberine inhibits intestinal carcinogenesis by suppressing intestinal pro-inflammatory genes and oncogenic factors through modulating gut microbiota.
BMC cancer.
2022 May; 22(1):566. doi:
10.1186/s12885-022-09635-9. [PMID: 35596224] - C Mesas, R Martínez, K Doello, R Ortiz, M López-Jurado, Francisco Bermúdez, F Quiñonero, J Prados, J M Porres, C Melguizo. In vivo antitumor activity of Euphorbia lathyris ethanol extract in colon cancer models.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2022 May; 149(?):112883. doi:
10.1016/j.biopha.2022.112883. [PMID: 35692123] - Zi-Yu Chang, Hsuan-Miao Liu, Yann-Lii Leu, Chung-Hua Hsu, Tzung-Yan Lee. Modulation of Gut Microbiota Combined with Upregulation of Intestinal Tight Junction Explains Anti-Inflammatory Effect of Corylin on Colitis-Associated Cancer in Mice.
International journal of molecular sciences.
2022 Feb; 23(5):. doi:
10.3390/ijms23052667. [PMID: 35269806] - Young Woo Cho, Young Hye Kwon. Regulation of gene expression in the development of colitis-associated colon cancer in mice fed a high-fat diet.
Biochemical and biophysical research communications.
2022 02; 592(?):81-86. doi:
10.1016/j.bbrc.2022.01.016. [PMID: 35033870] - Patrice Cunningham, Aman Sumal, Emma Patton, Henry Helms, Matthew T Noneman, Gustavo Martinez-Muñiz, Jackie E Bader, Ioulia Chatzistamou, Ahmed Aladhami, Christian Unger, Reilly T Enos, Hyeun Kyoo Shin, Kandy T Velázquez. Ojeok-san ameliorates visceral and somatic nociception in a mouse model of colitis induced colorectal cancer.
PloS one.
2022; 17(6):e0270338. doi:
10.1371/journal.pone.0270338. [PMID: 35737651] - Jia Yang, Hong Wei, Yunfei Zhou, Chun-Ho Szeto, Chuangen Li, Yufeng Lin, Olabisi O Coker, Harry Cheuk Hay Lau, Anthony W H Chan, Joseph J Y Sung, Jun Yu. High-Fat Diet Promotes Colorectal Tumorigenesis Through Modulating Gut Microbiota and Metabolites.
Gastroenterology.
2022 01; 162(1):135-149.e2. doi:
10.1053/j.gastro.2021.08.041. [PMID: 34461052] - Ahmet Uyar, Abdulahad Doğan, Turan Yaman, Ömer Faruk Keleş, Zabit Yener, İsmail Çelik, Elif Ebru Alkan. The Protective Role of Urtica dioica Seed Extract Against Azoxymethane-Induced Colon Carcinogenesis in Rats.
Nutrition and cancer.
2022; 74(1):306-319. doi:
10.1080/01635581.2021.1881568. [PMID: 33560145] - Jue Wang, Kang Ding, Yuhang Wang, Tingdong Yan, Yun Xu, Zirong Deng, Weiling Lin, Libei Zhang, Weizhong Zhu, Rui Zhao, Yuhang Zhou, Zhaoguo Liu. Wumei Pill Ameliorates AOM/DSS-Induced Colitis-Associated Colon Cancer through Inhibition of Inflammation and Oxidative Stress by Regulating S-Adenosylhomocysteine Hydrolase- (AHCY-) Mediated Hedgehog Signaling in Mice.
Oxidative medicine and cellular longevity.
2022; 2022(?):4061713. doi:
10.1155/2022/4061713. [PMID: 35927991] - Meng-Meng Zhang, Deng-Ke Yin, Xue-Lin Rui, Fu-Ping Shao, Jia-Cheng Li, Li Xu, Ye Yang. Protective effect of Pai-Nong-San against AOM/DSS-induced CAC in mice through inhibiting the Wnt signaling pathway.
Chinese journal of natural medicines.
2021 Dec; 19(12):912-920. doi:
10.1016/s1875-5364(22)60143-2. [PMID: 34961589] - Xiaoli Zhang, Weiwei Li, Yiming Ma, Xinhua Zhao, Longmei He, Peng Sun, Hongying Wang. High-fat diet aggravates colitis-associated carcinogenesis by evading ferroptosis in the ER stress-mediated pathway.
Free radical biology & medicine.
2021 12; 177(?):156-166. doi:
10.1016/j.freeradbiomed.2021.10.022. [PMID: 34688836] - Kimiya Shams, Mohaddeseh Larypoor, Jafar Salimian. The immunomodulatory effects of Candida albicans isolated from the normal gastrointestinal microbiome of the elderly on colorectal cancer.
Medical oncology (Northwood, London, England).
2021 Oct; 38(12):140. doi:
10.1007/s12032-021-01591-x. [PMID: 34637027] - Wael Mahmoud Aboulthana, Wafaa Ghoneim Shousha, Ehab Abdel-Raouf Essawy, Mahmoud Hosny Saleh, Alaa Hamed Salama. Assessment of the Anti-Cancer Efficiency of Silver Moringa oleifera Leaves Nano-extract against Colon Cancer Induced Chemically in Rats.
Asian Pacific journal of cancer prevention : APJCP.
2021 Oct; 22(10):3267-3286. doi:
10.31557/apjcp.2021.22.10.3267. [PMID: 34711004] - Fedia Baba-Ahmed, Kamilia Guedri, Fouzia Trea, Kheireddine Ouali. Protective role of a melon superoxide dismutase combined with gliadin (GliSODin) on the status of lipid peroxidation and antioxidant defense against azoxymethane-induced experimental colon carcinogenesis.
Journal of cancer research and therapeutics.
2021 Oct; 17(6):1445-1453. doi:
10.4103/jcrt.jcrt_175_19. [PMID: 34916376] - Daotong Li, Yu Feng, Meiling Tian, Xiaosong Hu, Ruimao Zheng, Fang Chen. Dietary Barley Leaf Mitigates Tumorigenesis in Experimental Colitis-Associated Colorectal Cancer.
Nutrients.
2021 Sep; 13(10):. doi:
10.3390/nu13103487. [PMID: 34684488] - Susu Pan, Kaili Yin, Zhiwei Tang, Shuren Wang, Zhuo Chen, Yirong Wang, Hongxia Zhu, Yunyun Han, Mei Liu, Man Jiang, Ningzhi Xu, Guo Zhang. Stimulation of hypothalamic oxytocin neurons suppresses colorectal cancer progression in mice.
eLife.
2021 09; 10(?):. doi:
10.7554/elife.67535. [PMID: 34528509] - Sha Zeng, Li Chen, Qiang Sun, Hui Zhao, Han Yang, Shan Ren, Maolun Liu, Xianli Meng, Haibo Xu. Scutellarin ameliorates colitis-associated colorectal cancer by suppressing Wnt/β-catenin signaling cascade.
European journal of pharmacology.
2021 Sep; 906(?):174253. doi:
10.1016/j.ejphar.2021.174253. [PMID: 34118224] - Nur Iliyani Mohd Ishak, Suhaila Mohamed, Iffah Nadhira Madzuki, Noordin Mohamed Mustapha, Norhaizan Mohd Esa. Limonin modulated immune and inflammatory responses to suppress colorectal adenocarcinoma in mice model.
Naunyn-Schmiedeberg's archives of pharmacology.
2021 09; 394(9):1907-1915. doi:
10.1007/s00210-021-02101-6. [PMID: 34009457] - Ahmed M Kabel, Ahmed M Ashour, Dina A Ali, Hany H Arab. The immunomodulatory effects of topiramate on azoxymethane-induced colon carcinogenesis in rats: The role of the inflammatory cascade, vascular endothelial growth factor, AKT/mTOR/MAP kinase signaling and the apoptotic markers.
International immunopharmacology.
2021 Sep; 98(?):107830. doi:
10.1016/j.intimp.2021.107830. [PMID: 34118646] - Hsin-Ling Yang, Hui-Wen Liu, Sirjana Shrestha, Varadharajan Thiyagarajan, Hui-Chi Huang, You-Cheng Hseu. Antrodia salmonea induces apoptosis and enhances cytoprotective autophagy in colon cancer cells.
Aging.
2021 05; 13(12):15964-15989. doi:
10.18632/aging.203019. [PMID: 34031264] - Juan Manuel García-Cordero, Nikte Y Martínez-Palma, Eduardo Madrigal-Bujaidar, Cristian Jiménez-Martínez, Eduardo Madrigal-Santillán, José A Morales-González, Rogelio Paniagua-Pérez, Isela Álvarez-González. Phaseolin, a Protein from the Seed of Phaseolus vulgaris, Has Antioxidant, Antigenotoxic, and Chemopreventive Properties.
Nutrients.
2021 May; 13(6):. doi:
10.3390/nu13061750. [PMID: 34063915] - Sarah P Short, Jennifer M Pilat, Caitlyn W Barrett, Vishruth K Reddy, Yael Haberman, Jared R Hendren, Benjamin J Marsh, Cody E Keating, Amy K Motley, Kristina E Hill, Anne E Zemper, M Kay Washington, Chanjuan Shi, Xi Chen, Keith T Wilson, Jeffrey S Hyams, Lee A Denson, Raymond F Burk, Michael J Rosen, Christopher S Williams. Colonic Epithelial-Derived Selenoprotein P Is the Source for Antioxidant-Mediated Protection in Colitis-Associated Cancer.
Gastroenterology.
2021 04; 160(5):1694-1708.e3. doi:
10.1053/j.gastro.2020.12.059. [PMID: 33388316] - Isaac J Morrison, Jianan Zhang, Jingwen Lin, JeAnn E Murray, Roy Porter, Moses K Langat, Nicholas J Sadgrove, James Barker, Guodong Zhang, Rupika Delgoda. Potential chemopreventive, anticancer and anti-inflammatory properties of a refined artocarpin-rich wood extract of Artocarpus heterophyllus Lam.
Scientific reports.
2021 03; 11(1):6854. doi:
10.1038/s41598-021-86040-5. [PMID: 33767225] - Guifeng Wang, Keiichi Hiramoto, Ning Ma, Nobuji Yoshikawa, Shiho Ohnishi, Mariko Murata, Shosuke Kawanishi. Glycyrrhizin Attenuates Carcinogenesis by Inhibiting the Inflammatory Response in a Murine Model of Colorectal Cancer.
International journal of molecular sciences.
2021 Mar; 22(5):. doi:
10.3390/ijms22052609. [PMID: 33807620] - Yonger Chen, Bingxin Wang, Xin Yuan, Yingyu Lu, Jiliang Hu, Jie Gao, Jizong Lin, Jian Liang, Shaozhen Hou, Shuxian Chen. Vitexin prevents colitis-associated carcinogenesis in mice through regulating macrophage polarization.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2021 Mar; 83(?):153489. doi:
10.1016/j.phymed.2021.153489. [PMID: 33571919] - Chao Yang, Yiying Zhao, Suji Im, Cindy Nakatsu, Yava Jones-Hall, Qing Jiang. Vitamin E delta-tocotrienol and metabolite 13'-carboxychromanol inhibit colitis-associated colon tumorigenesis and modulate gut microbiota in mice.
The Journal of nutritional biochemistry.
2021 03; 89(?):108567. doi:
10.1016/j.jnutbio.2020.108567. [PMID: 33347911] - Masaru Terasaki, Osamu Uehara, Shinya Ogasa, Taishi Sano, Atsuhito Kubota, Hiroyuki Kojima, Takuji Tanaka, Hayato Maeda, Kazuo Miyashita, Michihiro Mutoh. Alteration of fecal microbiota by fucoxanthin results in prevention of colorectal cancer in AOM/DSS mice.
Carcinogenesis.
2021 02; 42(2):210-219. doi:
10.1093/carcin/bgaa100. [PMID: 32940665] - Hongguang Liang, Zelong Lin, Youqiong Ye, Rongcheng Luo, Lixian Zeng. ARRB2 promotes colorectal cancer growth through triggering WTAP.
Acta biochimica et biophysica Sinica.
2021 Jan; 53(1):85-93. doi:
10.1093/abbs/gmaa151. [PMID: 33367479] - Tsuneyuki Miyazaki, Yohei Shirakami, Taku Mizutani, Akinori Maruta, Takayasu Ideta, Masaya Kubota, Hiroyasu Sakai, Takashi Ibuka, Salvatore Genovese, Serena Fiorito, Vito Alessandro Taddeo, Francesco Epifano, Takuji Tanaka, Masahito Shimizu. Novel FXR agonist nelumal A suppresses colitis and inflammation-related colorectal carcinogenesis.
Scientific reports.
2021 01; 11(1):492. doi:
10.1038/s41598-020-79916-5. [PMID: 33436792] - Huai-Chang Zhu, Xiao-Kang Jia, Yong Fan, Shao-Hua Xu, Xiao-Yan Li, Ming-Qing Huang, Meng-Liu Lan, Wen Xu, Shui-Sheng Wu. Alisol B 23-Acetate Ameliorates Azoxymethane/Dextran Sodium Sulfate-Induced Male Murine Colitis-Associated Colorectal Cancer via Modulating the Composition of Gut Microbiota and Improving Intestinal Barrier.
Frontiers in cellular and infection microbiology.
2021; 11(?):640225. doi:
10.3389/fcimb.2021.640225. [PMID: 33996624] - Alagesan Seetha, Halagowder Devaraj, Ganapasam Sudhandiran. Effects of combined treatment with Indomethacin and Juglone on AOM/DSS induced colon carcinogenesis in Balb/c mice: Roles of inflammation and apoptosis.
Life sciences.
2021 Jan; 264(?):118657. doi:
10.1016/j.lfs.2020.118657. [PMID: 33148421] - Liping Mao, Jinxue Yang, Jiaxin Yue, Yang Chen, Hongrui Zhou, Dongdong Fan, Qiuhua Zhang, Simone Buraschi, Renato V Iozzo, Xiuli Bi. Decorin deficiency promotes epithelial-mesenchymal transition and colon cancer metastasis.
Matrix biology : journal of the International Society for Matrix Biology.
2021 01; 95(?):1-14. doi:
10.1016/j.matbio.2020.10.001. [PMID: 33065248] - Turan Yaman, Ahmet Uyar, Ahmet Ufuk Kömüroğlu, Ömer Faruk Keleş, Zabit Yener. Chemopreventive efficacy of juniper berry oil (Juniperus communis L.) on azoxymethane-induced colon carcinogenesis in rat.
Nutrition and cancer.
2021; 73(1):133-146. doi:
10.1080/01635581.2019.1673450. [PMID: 31617778] - Haruki Horiguchi, Tsuyoshi Kadomatsu, Keishi Miyata, Kazutoyo Terada, Michio Sato, Daisuke Torigoe, Jun Morinaga, Toshiro Moroishi, Yuichi Oike. Stroma-derived ANGPTL2 establishes an anti-tumor microenvironment during intestinal tumorigenesis.
Oncogene.
2021 01; 40(1):55-67. doi:
10.1038/s41388-020-01505-7. [PMID: 33051596] - Jie Shen, Pei Li, Shuangshuang Liu, Qing Liu, Yue Li, Zheng Zhang, Chengmin Yang, Mengying Hu, Yuhua Sun, Chunnian He, Peigen Xiao. The chemopreventive effects of Huangqin-tea against AOM-induced preneoplastic colonic aberrant crypt foci in rats and omics analysis.
Food & function.
2020 Nov; 11(11):9634-9650. doi:
10.1039/d0fo01731k. [PMID: 33048099] - Han Li, Xin Xing, Xi Zhang, Liping Li, Zhenzhou Jiang, Tao Wang, Xin Huang, Xinzhi Wang, Luyong Zhang, Lixin Sun. Effects of triptolide on the sphingosine kinase - Sphingosine-1-phosphate signaling pathway in colitis-associated colon cancer.
International immunopharmacology.
2020 Nov; 88(?):106892. doi:
10.1016/j.intimp.2020.106892. [PMID: 32810834] - Miao Liu, Wenjie Xie, Xinyue Wan, Tao Deng. Clostridium butyricum modulates gut microbiota and reduces colitis associated colon cancer in mice.
International immunopharmacology.
2020 Nov; 88(?):106862. doi:
10.1016/j.intimp.2020.106862. [PMID: 32771947] - Yang Sun, Fanrong Diao, Yinbo Niu, Xiaoqiang Li, Huiping Zhou, Qibing Mei, Yuhua Li. Apple polysaccharide prevents from colitis-associated carcinogenesis through regulating macrophage polarization.
International journal of biological macromolecules.
2020 Oct; 161(?):704-711. doi:
10.1016/j.ijbiomac.2020.06.121. [PMID: 32544579] - Anastasios Angelou, Apostolos E Papalois, Efstathios Antoniou, Jaeyun Wang, Neda Amini, Anastasia Pikouli, Nikolaos Andreatos, Stefan Buettner, Muhammad Munir, Georgios Theodoropoulos, Georgios C Zografos, Panagiotis Sarantis, Alessandra Pulvirenti, Carsten Kamphues, Stamatios Theocharis, Emmanouil Pikoulis, Georgios Antonios Margonis. The Interplay Between Innate Immunity (TLR-4) and sCD40L in the Context of an Animal Model of Colitis-associated Cancer.
Anticancer research.
2020 Oct; 40(10):5457-5462. doi:
10.21873/anticanres.14556. [PMID: 32988867] - Risheng Zhao, Olabisi Oluwabukola Coker, Jianlin Wu, Yunfei Zhou, Liuyang Zhao, Geicho Nakatsu, Xiqing Bian, Hong Wei, Anthony W H Chan, Joseph J Y Sung, Francis K L Chan, Emad El-Omar, Jun Yu. Aspirin Reduces Colorectal Tumor Development in Mice and Gut Microbes Reduce its Bioavailability and Chemopreventive Effects.
Gastroenterology.
2020 09; 159(3):969-983.e4. doi:
10.1053/j.gastro.2020.05.004. [PMID: 32387495] - Elsayed I Salim, Mona M El-Gamal, Mahy M Mona, Hanaa A Abdelhady. Attenuation of Rat Colon Carcinogenesis by Styela plicata Aqueous Extract. Modulation of NF-κB Pathway and Cytoplasmic Sod1 Gene Expression.
Asian Pacific journal of cancer prevention : APJCP.
2020 Sep; 21(9):2739-2750. doi:
10.31557/apjcp.2020.21.9.2739. [PMID: 32986376] - David Bars-Cortina, Ana Martínez-Bardají, Alba Macià, María-Jose Motilva, Carme Piñol-Felis. Consumption evaluation of one apple flesh a day in the initial phases prior to adenoma/adenocarcinoma in an azoxymethane rat colon carcinogenesis model.
The Journal of nutritional biochemistry.
2020 09; 83(?):108418. doi:
10.1016/j.jnutbio.2020.108418. [PMID: 32592950] - Valeria Josa, Szilamer Ferenczi, Rita Szalai, Eniko Fuder, Daniel Kuti, Krisztina Horvath, Nikolett Hegedus, Tibor Kovacs, Gergo Bagamery, Balazs Juhasz, Zsuzsanna Winkler, Daniel S Veres, Zsombor Zrubka, Domokos Mathe, Zsolt Baranyai. Thrombocytosis and Effects of IL-6 Knock-Out in a Colitis-Associated Cancer Model.
International journal of molecular sciences.
2020 Aug; 21(17):. doi:
10.3390/ijms21176218. [PMID: 32867390] - Bowei Zhang, Yingchuan Xu, Shuang Liu, Huan Lv, Yaozhong Hu, Yaya Wang, Zhi Li, Jin Wang, Xuemeng Ji, Hui Ma, Xiaowen Wang, Shuo Wang. Dietary Supplementation of Foxtail Millet Ameliorates Colitis-Associated Colorectal Cancer in Mice via Activation of Gut Receptors and Suppression of the STAT3 Pathway.
Nutrients.
2020 Aug; 12(8):. doi:
10.3390/nu12082367. [PMID: 32784751] - Jun Fang, Shanghui Gao, Rayhanul Islam, Yuji Teramoto, Hiroshi Maeda. Extracts of Phellinus linteus, Bamboo (Sasa senanensis) Leaf and Chaga Mushroom (Inonotus obliquus) Exhibit Antitumor Activity through Activating Innate Immunity.
Nutrients.
2020 Jul; 12(8):. doi:
10.3390/nu12082279. [PMID: 32751371] - Candice Mazewski, Diego Luna-Vital, Mark Berhow, Elvira Gonzalez de Mejia. Reduction of colitis-associated colon carcinogenesis by a black lentil water extract through inhibition of inflammatory and immunomodulatory cytokines.
Carcinogenesis.
2020 07; 41(6):790-803. doi:
10.1093/carcin/bgaa008. [PMID: 32002542] - Qing Wang, Kaicen Wang, Wenrui Wu, Longxian Lv, Xiaoyuan Bian, Liya Yang, Qiangqiang Wang, Yating Li, Jianzhong Ye, Daiqiong Fang, Jingjing Wu, Xianwan Jiang, Jiaojiao Xie, Yanmeng Lu, Lanjuan Li. Administration of Bifidobacterium bifidum CGMCC 15068 modulates gut microbiota and metabolome in azoxymethane (AOM)/dextran sulphate sodium (DSS)-induced colitis-associated colon cancer (CAC) in mice.
Applied microbiology and biotechnology.
2020 Jul; 104(13):5915-5928. doi:
10.1007/s00253-020-10621-z. [PMID: 32367312] - Hua Sui, Hongsheng Tan, Jie Fu, Qing Song, Ru Jia, Li Han, Yue Lv, Hong Zhang, Dan Zheng, Liping Dong, Songpo Wang, Qi Li, Hongxi Xu. The active fraction of Garcinia yunnanensis suppresses the progression of colorectal carcinoma by interfering with tumorassociated macrophage-associated M2 macrophage polarization in vivo and in vitro.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2020 06; 34(6):7387-7403. doi:
10.1096/fj.201903011r. [PMID: 32283574] - Wael Mahmoud Aboulthana, Noha El-Sayed Ibrahim, Noha Mohamed Osman, Mohamed Mahmoud Seif, Amgad Kamal Hassan, Ahmed Mahmoud Youssef, Amal Mostafa El-Feky, A A Madboli. Evaluation of the Biological Efficiency of Silver Nanoparticles Biosynthesized Using Croton tiglium L. Seeds Extract against Azoxymethane Induced Colon Cancer in Rats.
Asian Pacific journal of cancer prevention : APJCP.
2020 May; 21(5):1369-1389. doi:
10.31557/apjcp.2020.21.5.1369. [PMID: 32458646] - Jia-Le Song, Jung-Sook Lee, Hee-Young Kim, Byung-Jin Jeong, Jong-Sung Jeong, Tae-Gon Huh, Kun-Young Park. Dietary Mixed Cereal Grains Ameliorate the Azoxymethane and Dextran Sodium Sulfate-Induced Colonic Carcinogenesis in C57BL/6J Mice.
Journal of medicinal food.
2020 Apr; 23(4):440-452. doi:
10.1089/jmf.2019.4540. [PMID: 32186945] - Ruipeng Yang, Shuhua Shan, Chen Zhang, Jiangying Shi, Hanqing Li, Zhuoyu Li. Inhibitory Effects of Bound Polyphenol from Foxtail Millet Bran on Colitis-Associated Carcinogenesis by the Restoration of Gut Microbiota in a Mice Model.
Journal of agricultural and food chemistry.
2020 Mar; 68(11):3506-3517. doi:
10.1021/acs.jafc.0c00370. [PMID: 32100999] - Jun Guo, Zhe Yang, Hongrui Zhou, Jiaxin Yue, Teng Mu, Qiuhua Zhang, Xiuli Bi. Upregulation of DKK3 by miR-483-3p plays an important role in the chemoprevention of colorectal cancer mediated by black raspberry anthocyanins.
Molecular carcinogenesis.
2020 02; 59(2):168-178. doi:
10.1002/mc.23138. [PMID: 31763724] - Brandi Jefferson, Malaika Ali, Stephanie Grant, Gabriel Frampton, Michaela Ploof, Sarah Andry, Sharon DeMorrow, Matthew McMillin. Thrombospondin-1 Exacerbates Acute Liver Failure and Hepatic Encephalopathy Pathology in Mice by Activating Transforming Growth Factor β1.
The American journal of pathology.
2020 02; 190(2):347-357. doi:
10.1016/j.ajpath.2019.10.003. [PMID: 31734229] - Srinivasan Periasamy, Wang-Hung Wu, Se-Ping Chien, Chuan-Teng Liu, Ming-Yie Liu. Dietary Ziziphus jujuba Fruit Attenuates Colitis-Associated Tumorigenesis: A Pivotal Role of the NF-κB/IL-6/JAK1/STAT3 Pathway.
Nutrition and cancer.
2020; 72(1):120-132. doi:
10.1080/01635581.2019.1615515. [PMID: 31135224] - Shichang Bian, Hongjuan Wan, Xinyan Liao, Weisheng Wang. Inhibitory Effects of Apigenin on Tumor Carcinogenesis by Altering the Gut Microbiota.
Mediators of inflammation.
2020; 2020(?):7141970. doi:
10.1155/2020/7141970. [PMID: 33082711] - Haitao Chen, Fan Zhang, Jin Zhang, Xinjie Zhang, Yong Guo, Qinghua Yao. A Holistic View of Berberine Inhibiting Intestinal Carcinogenesis in Conventional Mice Based on Microbiome-Metabolomics Analysis.
Frontiers in immunology.
2020; 11(?):588079. doi:
10.3389/fimmu.2020.588079. [PMID: 33072135] - Guifeng Wang, Ning Ma, Feng He, Shosuke Kawanishi, Hatasu Kobayashi, Shinji Oikawa, Mariko Murata. Taurine Attenuates Carcinogenicity in Ulcerative Colitis-Colorectal Cancer Mouse Model.
Oxidative medicine and cellular longevity.
2020; 2020(?):7935917. doi:
10.1155/2020/7935917. [PMID: 32566100] - Rui Lin, Meiyu Piao, Yan Song, Chunyan Liu. Quercetin Suppresses AOM/DSS-Induced Colon Carcinogenesis through Its Anti-Inflammation Effects in Mice.
Journal of immunology research.
2020; 2020(?):9242601. doi:
10.1155/2020/9242601. [PMID: 32537472] - Yanfei Chen, Masako Nakanishi, Eddy J Bautista, Veneta Qendro, Erica Sodergren, Daniel W Rosenberg, George M Weinstock. Colon Cancer Prevention with Walnuts: A Longitudinal Study in Mice from the Perspective of a Gut Enterotype-like Cluster.
Cancer prevention research (Philadelphia, Pa.).
2020 01; 13(1):15-24. doi:
10.1158/1940-6207.capr-19-0273. [PMID: 31818852] - Junichi Kato, Yohei Shirakami, Masaya Ohnishi, Taku Mizutani, Masaya Kubota, Hiroyasu Sakai, Takashi Ibuka, Takuji Tanaka, Masahito Shimizu. Suppressive effects of the sodium‑glucose cotransporter 2 inhibitor tofogliflozin on colorectal tumorigenesis in diabetic and obese mice.
Oncology reports.
2019 Dec; 42(6):2797-2805. doi:
10.3892/or.2019.7357. [PMID: 31638239] - Satoshi Yokoyama, Keiichi Hiramoto, Yurika Yamate. Impaired skin barrier function caused by reactive oxygen species in mice with colonic tumours.
Cutaneous and ocular toxicology.
2019 Dec; 38(4):349-355. doi:
10.1080/15569527.2019.1622559. [PMID: 31137980] - Chunsaier Wang, Wenbin Li, Hongying Wang, Yiming Ma, Xinhua Zhao, Xudong Zhang, Hong Yang, Jiaming Qian, Jingnan Li. Saccharomyces boulardii alleviates ulcerative colitis carcinogenesis in mice by reducing TNF-α and IL-6 levels and functions and by rebalancing intestinal microbiota.
BMC microbiology.
2019 11; 19(1):246. doi:
10.1186/s12866-019-1610-8. [PMID: 31694526] - Aarón Kuri-García, Alejandra González-Reyes, Paola Jazmín Aranda-Vargas, Ulisses Moreno Celis, Carmen Mejía, Teresa García-Gasca, Roberto Augusto Ferríz-Martínez, Karina de la Torre-Carbot, Carlos Saldaña Gutiérrez, Jorge Luis Chávez-Servín. Effect on nutritional markers of a model of aberrant crypt foci induced by azoxymethane and sodium dextran sulfate in Sprague Dawley rats.
Nutricion hospitalaria.
2019 Oct; 36(5):1163-1170. doi:
10.20960/nh.02600. [PMID: 31516013] - Min Guo, Zhuoyu Li. Polysaccharides isolated from Nostoc commune Vaucher inhibit colitis-associated colon tumorigenesis in mice and modulate gut microbiota.
Food & function.
2019 Oct; 10(10):6873-6881. doi:
10.1039/c9fo00296k. [PMID: 31584586] - Sherien M El-Daly, Safaa M Morsy, Dalia Medhat, Mona A El-Bana, Yasmin Abdel Latif, Enayat A Omara, Jackleen R Awadallah, Amira M Gamal-Eldeen. The diagnostic efficacy of circulating miRNAs in monitoring the early development of colitis-induced colorectal cancer.
Journal of cellular biochemistry.
2019 10; 120(10):16668-16680. doi:
10.1002/jcb.28925. [PMID: 31095784] - Li Zhang, Xin Qiao, Meihong Chen, Ping Li, Xiaodong Wen, Minhui Sun, Xiaonan Ma, Yingjian Hou, Jie Yang. Ilexgenin A prevents early colonic carcinogenesis and reprogramed lipid metabolism through HIF1α/SREBP-1.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2019 Oct; 63(?):153011. doi:
10.1016/j.phymed.2019.153011. [PMID: 31301538] - Shahram Agah, Ali Mohammad Alizadeh, Maryam Mosavi, Peyman Ranji, Hossein Khavari-Daneshvar, Farnaz Ghasemian, Sahar Bahmani, Abbas Tavassoli. More Protection of Lactobacillus acidophilus Than Bifidobacterium bifidum Probiotics on Azoxymethane-Induced Mouse Colon Cancer.
Probiotics and antimicrobial proteins.
2019 09; 11(3):857-864. doi:
10.1007/s12602-018-9425-8. [PMID: 29682678] - Aarón Kuri-García, Rosa Iris Godínez-Santillán, Carmen Mejía, Roberto Augusto Ferriz-Martínez, Pablo García-Solís, Alejandro Enríquez-Vázquez, Teresa García-Gasca, Salvador Horacio Guzmán-Maldonado, Jorge Luis Chávez-Servín. Preventive Effect of an Infusion of the Aqueous Extract of Chaya Leaves (Cnidoscolus aconitifolius) in an Aberrant Crypt Foci Rat Model Induced by Azoxymethane and Dextran Sulfate Sodium.
Journal of medicinal food.
2019 Aug; 22(8):851-860. doi:
10.1089/jmf.2019.0031. [PMID: 31074673] - Van-Long Truong, Min Ji Bak, Woo-Sik Jeong. Chemopreventive Activity of Red Ginseng Oil in a Mouse Model of Azoxymethane/Dextran Sulfate Sodium-Induced Inflammation-Associated Colon Carcinogenesis.
Journal of medicinal food.
2019 Jun; 22(6):578-586. doi:
10.1089/jmf.2018.4328. [PMID: 30864851] - Weicang Wang, Jun Yang, Matthew L Edin, Yuxin Wang, Ying Luo, Debin Wan, Haixia Yang, Chun-Qing Song, Wen Xue, Katherine Z Sanidad, Mingyue Song, Heather A Bisbee, Jennifer A Bradbury, Guanjun Nan, Jianan Zhang, Pei-An Betty Shih, Kin Sing Stephen Lee, Lisa M Minter, Daeyoung Kim, Hang Xiao, Jun-Yan Liu, Bruce D Hammock, Darryl C Zeldin, Guodong Zhang. Targeted Metabolomics Identifies the Cytochrome P450 Monooxygenase Eicosanoid Pathway as a Novel Therapeutic Target of Colon Tumorigenesis.
Cancer research.
2019 04; 79(8):1822-1830. doi:
10.1158/0008-5472.can-18-3221. [PMID: 30803995] - Bo Li, Yan Wang, Lijuan Yin, Gaoxiang Huang, Yi Xu, Jie Su, Liye Ma, Jian Lu. Glucocorticoids promote the development of azoxymethane and dextran sulfate sodium-induced colorectal carcinoma in mice.
BMC cancer.
2019 Jan; 19(1):94. doi:
10.1186/s12885-019-5299-8. [PMID: 30665389] - Jae Gon Lee, Chang Soo Eun, Su Vin Jo, A-Reum Lee, Chan Hyuk Park, Dong Soo Han. The impact of gut microbiota manipulation with antibiotics on colon tumorigenesis in a murine model.
PloS one.
2019; 14(12):e0226907. doi:
10.1371/journal.pone.0226907. [PMID: 31860645] - Karen Triff, Mathew W McLean, Evelyn Callaway, Jennifer Goldsby, Ivan Ivanov, Robert S Chapkin. Dietary fat and fiber interact to uniquely modify global histone post-translational epigenetic programming in a rat colon cancer progression model.
International journal of cancer.
2018 09; 143(6):1402-1415. doi:
10.1002/ijc.31525. [PMID: 29659013] - Océane C B Martin, Nathalie Naud, Sylviane Taché, Laurent Debrauwer, Sylvie Chevolleau, Jacques Dupuy, Céline Chantelauze, Denis Durand, Estelle Pujos-Guillot, Florence Blas-Y-Estrada, Christine Urbano, Gunter G C Kuhnle, Véronique Santé-Lhoutellier, Thierry Sayd, Didier Viala, Adeline Blot, Nathalie Meunier, Pascal Schlich, Didier Attaix, Françoise Guéraud, Valérie Scislowski, Denis E Corpet, Fabrice H F Pierre. Targeting Colon Luminal Lipid Peroxidation Limits Colon Carcinogenesis Associated with Red Meat Consumption.
Cancer prevention research (Philadelphia, Pa.).
2018 09; 11(9):569-580. doi:
10.1158/1940-6207.capr-17-0361. [PMID: 29954759] - Samsu U Nurdin, Richard K Le Leu, Arturo Aburto-Medina, Graeme P Young, James C R Stangoulis, Andy S Ball, Catherine A Abbott. Effects of Dietary Fibre from the Traditional Indonesian Food, Green Cincau (Premna oblongifolia Merr.) on Preneoplastic Lesions and Short Chain Fatty Acid Production in an Azoxymethane Rat Model of Colon Cancer.
International journal of molecular sciences.
2018 Aug; 19(9):. doi:
10.3390/ijms19092593. [PMID: 30200383] - Stephanie Grant, Matthew McMillin, Gabriel Frampton, Anca D Petrescu, Elaina Williams, Victoria Jaeger, Jessica Kain, Sharon DeMorrow. Direct Comparison of the Thioacetamide and Azoxymethane Models of Type A Hepatic Encephalopathy in Mice.
Gene expression.
2018 08; 18(3):171-185. doi:
10.3727/105221618x15287315176503. [PMID: 29895352] - Shuangjiao Deng, Hongfei Wang, Heng Fan, Lijuan Zhang, Jianli Hu, Qing Tang, Zhexing Shou, Xingxing Liu, Dongmei Zuo, Jia Yang, Meng Xu, Qianyun Chen, Yalan Dong, Zhen Nan, Hui Wu, Yujin Liu. Over-expressed miRNA-200b ameliorates ulcerative colitis-related colorectal cancer in mice through orchestrating epithelial-mesenchymal transition and inflammatory responses by channel of AKT2.
International immunopharmacology.
2018 Aug; 61(?):346-354. doi:
10.1016/j.intimp.2018.06.024. [PMID: 29933193] - Hyeon-Hui Ki, Ji-Hyun Lee, Hoon-Yeon Lee, Young-Mi Lee, Dae-Ki Kim. Triticum aestivum Sprouts Extract Inhibits Azoymethane (AOM)/Dextran Sodium Sulfate (DSS)-Induced Colon Carcinogenesis in Mice.
Nutrition and cancer.
2018 Aug; 70(6):928-937. doi:
10.1080/01635581.2018.1490447. [PMID: 30273050] - Hua-Li Song, Dong-Mei Zhang, Heng Wen, Meng Wang, Na Zhao, Yu-Hua Gao, Ni Ding. Peritoneal lavage with povidone-iodine solution in colorectal cancer-induced rats.
The Journal of surgical research.
2018 08; 228(?):93-99. doi:
10.1016/j.jss.2018.02.055. [PMID: 29907236] - Kayo Masago, Yasuyuki Kihara, Keisuke Yanagida, Fumie Hamano, Shinsuke Nakagawa, Masami Niwa, Takao Shimizu. Lysophosphatidic acid receptor, LPA6, regulates endothelial blood-brain barrier function: Implication for hepatic encephalopathy.
Biochemical and biophysical research communications.
2018 07; 501(4):1048-1054. doi:
10.1016/j.bbrc.2018.05.106. [PMID: 29778535] - Isabel Andújar, Alberto Martí-Rodrigo, Rosa María Giner, José Luis Ríos, María Carmen Recio. Shikonin Prevents Early Phase Inflammation Associated with Azoxymethane/Dextran Sulfate Sodium-Induced Colon Cancer and Induces Apoptosis in Human Colon Cancer Cells.
Planta medica.
2018 Jul; 84(9-10):674-683. doi:
10.1055/a-0599-1145. [PMID: 29642242]
