Azepexole (BioDeep_00000176372)

   

human metabolite blood metabolite


代谢物信息卡片


2-Amino-6-ethyl-4,5,7,8-tetrahydro-6H-oxazolo(5,4-D)azepine dihydrochloride

化学式: C9H15N3O (181.12150599999998)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(blood) 97.49%

分子结构信息

SMILES: CCN1CCC2=C(CC1)N=C(N)O2
InChI: InChI=1S/C9H15N3O/c1-2-12-5-3-7-8(4-6-12)13-9(10)11-7/h2-6H2,1H3,(H2,10,11)

描述信息

C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C87053 - Adrenergic Agonist
D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists
D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents
D002317 - Cardiovascular Agents > D014662 - Vasoconstrictor Agents

同义名列表

9 个代谢物同义名

2-Amino-6-ethyl-4,5,7,8-tetrahydro-6H-oxazolo(5,4-D)azepine dihydrochloride; 6-ethyl-4H,5H,6H,7H,8H-[1,3]oxazolo[4,5-d]azepin-2-amine; 6-ethyl-4H,5H,7H,8H-[1,3]oxazolo[4,5-d]azepin-2-amine; Azepexole, dihydrochloride; Azepexole; b HT-933; Azepoxol; b-HT 933; BHT 933



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

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  • U Deniz Dincer, Alberto G Araiza, Jarrod D Knudson, Patricia E Molina, Johnathan D Tune. Sensitization of coronary alpha-adrenoceptor vasoconstriction in the prediabetic metabolic syndrome. Microcirculation (New York, N.Y. : 1994). 2006 Oct; 13(7):587-95. doi: 10.1080/10739680600885228. [PMID: 16990217]
  • F A Gesek. Alpha1- and alpha2-adrenoceptor control of sodium transport reverses in developing hypertension. Hypertension (Dallas, Tex. : 1979). 1999 Jan; 33(1 Pt 2):524-9. doi: 10.1161/01.hyp.33.1.524. [PMID: 9931159]
  • G Lembo, G Iaccarino, C Vecchione, E Barbato, R Izzo, D Fontana, B Trimarco. Insulin modulation of an endothelial nitric oxide component present in the alpha2- and beta-adrenergic responses in human forearm. The Journal of clinical investigation. 1997 Oct; 100(8):2007-14. doi: 10.1172/jci119732. [PMID: 9329964]
  • Q P Feng, A Bergdahl, X R Lu, X Y Sun, L Edvinsson, T Hedner. Vascular alpha-2 adrenoceptor function is decreased in rats with congestive heart failure. Cardiovascular research. 1996 Apr; 31(4):577-84. doi: NULL. [PMID: 8689649]
  • S C Thomson, V Vallon. Alpha 2-adrenoceptors determine the response to nitric oxide inhibition in the rat glomerulus and proximal tubule. Journal of the American Society of Nephrology : JASN. 1995 Nov; 6(5):1482-90. doi: 10.1681/asn.v651482. [PMID: 8589327]
  • C Indolfi, A Maione, M Volpe, A Rapacciuolo, G Esposito, R Ceravolo, V Rendina, M Condorelli, M Chiariello. Forearm vascular responsiveness to alpha 1- and alpha 2-adrenoceptor stimulation in patients with congestive heart failure. Circulation. 1994 Jul; 90(1):17-22. doi: 10.1161/01.cir.90.1.17. [PMID: 7913001]
  • C Indolfi, F Piscione, B Villari, E Russolillo, V Rendina, P Golino, M Condorelli, M Chiariello. Role of alpha 2-adrenoceptors in normal and atherosclerotic human coronary circulation. Circulation. 1992 Oct; 86(4):1116-24. doi: 10.1161/01.cir.86.4.1116. [PMID: 1356656]
  • S C Thomson, F B Gabbai, B J Tucker, R C Blantz. Interaction between alpha 2-adrenergic and angiotensin II systems in the control of glomerular hemodynamics as assessed by renal micropuncture in the rat. The Journal of clinical investigation. 1992 Aug; 90(2):604-11. doi: 10.1172/jci115899. [PMID: 1353766]
  • R L Kline, P F Mercer. Contribution of renal nerves to the natriuretic and diuretic effect of alpha-2 adrenergic receptor activation. The Journal of pharmacology and experimental therapeutics. 1990 Apr; 253(1):266-71. doi: NULL. [PMID: 1970360]
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