Azepexole (BioDeep_00000176372)
human metabolite blood metabolite
代谢物信息卡片
化学式: C9H15N3O (181.12150599999998)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 97.49%
分子结构信息
SMILES: CCN1CCC2=C(CC1)N=C(N)O2
InChI: InChI=1S/C9H15N3O/c1-2-12-5-3-7-8(4-6-12)13-9(10)11-7/h2-6H2,1H3,(H2,10,11)
描述信息
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C87053 - Adrenergic Agonist
D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists
D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents
D002317 - Cardiovascular Agents > D014662 - Vasoconstrictor Agents
同义名列表
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
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2006 Oct; 13(7):587-95. doi:
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Hypertension (Dallas, Tex. : 1979).
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The Journal of clinical investigation.
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Cardiovascular research.
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1995 Nov; 6(5):1482-90. doi:
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Circulation.
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. [PMID: 7913001] - C Indolfi, F Piscione, B Villari, E Russolillo, V Rendina, P Golino, M Condorelli, M Chiariello. Role of alpha 2-adrenoceptors in normal and atherosclerotic human coronary circulation.
Circulation.
1992 Oct; 86(4):1116-24. doi:
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. [PMID: 1356656] - S C Thomson, F B Gabbai, B J Tucker, R C Blantz. Interaction between alpha 2-adrenergic and angiotensin II systems in the control of glomerular hemodynamics as assessed by renal micropuncture in the rat.
The Journal of clinical investigation.
1992 Aug; 90(2):604-11. doi:
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. [PMID: 1353766] - R L Kline, P F Mercer. Contribution of renal nerves to the natriuretic and diuretic effect of alpha-2 adrenergic receptor activation.
The Journal of pharmacology and experimental therapeutics.
1990 Apr; 253(1):266-71. doi:
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The American journal of physiology.
1990 Mar; 258(3 Pt 2):F636-42. doi:
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The American journal of physiology.
1990 Jan; 258(1 Pt 2):F21-7. doi:
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. [PMID: 1967910] - J F Aubert, B Waeber, B Rossier, K Geering, J Nussberger, H R Brunner. Effects of neuropeptide Y on the blood pressure response to various vasoconstrictor agents.
The Journal of pharmacology and experimental therapeutics.
1988 Sep; 246(3):1088-92. doi:
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The American journal of physiology.
1988 Aug; 255(2 Pt 2):F317-23. doi:
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. [PMID: 2900606] - R M Edwards, M Gellai. Inhibition of vasopressin-stimulated cyclic AMP accumulation by alpha-2 adrenoceptor agonists in isolated papillary collecting ducts.
The Journal of pharmacology and experimental therapeutics.
1988 Feb; 244(2):526-30. doi:
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. [PMID: 2894453] - D D Smyth, S Umemura, E Yang, W A Pettinger. Inhibition of renin release by alpha-adrenoceptor stimulation in the isolated perfused rat kidney.
European journal of pharmacology.
1987 Aug; 140(1):33-8. doi:
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Canadian journal of physiology and pharmacology.
1987 Jul; 65(7):1421-7. doi:
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. [PMID: 2889516] - B Stanton, E Puglisi, M Gellai. Localization of alpha 2-adrenoceptor-mediated increase in renal Na+, K+, and water excretion.
The American journal of physiology.
1987 Jun; 252(6 Pt 2):F1016-21. doi:
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The Journal of pharmacology and experimental therapeutics.
1987 Mar; 240(3):723-8. doi:
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Fundamental & clinical pharmacology.
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British journal of pharmacology.
1987 Jan; 90(1):61-70. doi:
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Neuroendocrinology.
1986; 42(5):416-20. doi:
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. [PMID: 3703161] - S Umemura, D D Smyth, W A Pettinger. Alpha 2-adrenoceptor stimulation and cellular cAMP levels in microdissected rat glomeruli.
The American journal of physiology.
1986 Jan; 250(1 Pt 2):F103-8. doi:
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Life sciences.
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1982 Jul; 4(4):527-30. doi:
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