Avilamycin (BioDeep_00000176326)

   

human metabolite blood metabolite


代谢物信息卡片


6-[6-({2-[(6-{7-acetyl-6-methyl-7-[(2-methylpropanoyl)oxy]-octahydro-2H,3ah-2,4-spirobi[[1,3]dioxolo[4,5-c]pyran]-7-oloxy}-4-hydroxy-5-methoxy-2-(methoxymethyl)oxan-3-yl)oxy]-3-hydroxy-5-methoxy-6-methyloxan-4-yl}oxy)-4,6,7a-trimethyl-tetrahydro-3ah-spiro[[1,3]dioxolo[4,5-c]pyran-2,2-oxane]-4-oloxy]-4-hydroxy-2-methyloxan-3-yl 3,5-dichloro-4-hydroxy-2-methoxy-6-methylbenzoic acid

化学式: C61H88Cl2O32 (1402.4635508000001)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1C(C(CC(O1)OC2C(OC3(CC2O)OC4C(OC(CC4(O3)C)OC5C(C(OC(C5OC)C)OC6C(OC(C(C6O)OC)OC7C(C8C(CO7)OC9(O8)C1C(C(C(O9)C)(C(=O)C)O)OCO1)OC(=O)C(C)C)COC)O)C)C)O)OC(=O)C1=C(C(=C(C(=C1OC)Cl)O)Cl)C
InChI: InChI=1S/C61H88Cl2O32/c1-21(2)53(70)87-49-45-32(92-61(93-45)52-51(78-20-79-52)60(72,27(8)64)28(9)91-61)19-77-56(49)89-57-48(76-14)39(68)44(31(83-57)18-73-11)88-55-40(69)47(43(74-12)24(5)82-55)85-34-17-58(10)50(26(7)81-34)94-59(95-58)16-30(66)42(25(6)90-59)84-33-15-29(65)41(23(4)80-33)86-54(71)35-22(3)36(62)38(67)37(63)46(35)75-13/h21,23-26,28-34,39-45,47-52,55-57,65-69,72H,15-20H2,1-14H3

描述信息

同义名列表

5 个代谢物同义名

6-[6-({2-[(6-{7-acetyl-6-methyl-7-[(2-methylpropanoyl)oxy]-octahydro-2H,3ah-2,4-spirobi[[1,3]dioxolo[4,5-c]pyran]-7-oloxy}-4-hydroxy-5-methoxy-2-(methoxymethyl)oxan-3-yl)oxy]-3-hydroxy-5-methoxy-6-methyloxan-4-yl}oxy)-4,6,7a-trimethyl-tetrahydro-3ah-spiro[[1,3]dioxolo[4,5-c]pyran-2,2-oxane]-4-oloxy]-4-hydroxy-2-methyloxan-3-yl 3,5-dichloro-4-hydroxy-2-methoxy-6-methylbenzoic acid; 6-[6-({2-[(6-{7-acetyl-6-methyl-7-[(2-methylpropanoyl)oxy]-octahydro-2H,3aH-2,4-spirobi[[1,3]dioxolo[4,5-c]pyran]-7-oloxy}-4-hydroxy-5-methoxy-2-(methoxymethyl)oxan-3-yl)oxy]-3-hydroxy-5-methoxy-6-methyloxan-4-yl}oxy)-4,6,7a-trimethyl-tetrahydro-3aH-spiro[[1,3]dioxolo[4,5-c]pyran-2,2-oxane]-4-oloxy]-4-hydroxy-2-methyloxan-3-yl 3,5-dichloro-4-hydroxy-2-methoxy-6-methylbenzoate; 6-[6-({2-[(6-{7-acetyl-6-methyl-7-[(2-methylpropanoyl)oxy]-octahydro-3aH-2,4-spirobi[[1,3]dioxolo[4,5-c]pyran]-7-oloxy}-4-hydroxy-5-methoxy-2-(methoxymethyl)oxan-3-yl)oxy]-3-hydroxy-5-methoxy-6-methyloxan-4-yl}oxy)-4,6,7a-trimethyl-tetrahydrospiro[[1,3]dioxolo[4,5-c]pyran-2,2-oxane]-4-oloxy]-4-hydroxy-2-methyloxan-3-yl 3,5-dichloro-4-hydroxy-2-methoxy-6-methylbenzoate; Avilamycin-A; Avilamycin



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Guanghai Yu, Haifen Peng, Jian Cao, Aimei Liao, Pan Long, Jihong Huang, Ming Hui. Avilamycin production enhancement by mutagenesis and fermentation optimization in Streptomyces viridochromogenes. World journal of microbiology & biotechnology. 2022 Jan; 38(3):50. doi: 10.1007/s11274-021-03191-3. [PMID: 35098381]
  • G-B Kim, Y M Seo, C H Kim, I K Paik. Effect of dietary prebiotic supplementation on the performance, intestinal microflora, and immune response of broilers. Poultry science. 2011 Jan; 90(1):75-82. doi: 10.3382/ps.2010-00732. [PMID: 21177446]
  • F Hernández, V García, J Madrid, J Orengo, P Catalá, M D Megías. Effect of formic acid on performance, digestibility, intestinal histomorphology and plasma metabolite levels of broiler chickens. British poultry science. 2006 Feb; 47(1):50-6. doi: 10.1080/00071660500475574. [PMID: 16546797]
  • Thomas J Burnett. Avilamycin is poorly absorbed, is extensively metabolized by swine and is not persistent in the environment. Journal of mass spectrometry : JMS. 2005 Nov; 40(11):1505. doi: 10.1002/jms.920. [PMID: 16255060]
  • P Butaye, L A Devriese, F Haesebrouck. Effect of avilamycin fed to chickens on E. faecium counts and on the selection of avilamycin-resistant E. faecium populations. Microbial drug resistance (Larchmont, N.Y.). 2005; 11(2):170-7. doi: 10.1089/mdr.2005.11.170. [PMID: 15910233]
  • A A Delsol, L Randall, S Cooles, M J Woodward, J Sunderland, J M Roe. Effect of the growth promoter avilamycin on emergence and persistence of antimicrobial resistance in enteric bacteria in the pig. Journal of applied microbiology. 2005; 98(3):564-71. doi: 10.1111/j.1365-2672.2004.02461.x. [PMID: 15715858]
  • Ane Knarreborg, Charlotte Lauridsen, Ricarda M Engberg, Søren K Jensen. Dietary antibiotic growth promoters enhance the bioavailability of alpha-tocopheryl acetate in broilers by altering lipid absorption. The Journal of nutrition. 2004 Jun; 134(6):1487-92. doi: 10.1093/jn/134.6.1487. [PMID: 15173416]
  • M Hinton. Salmonella colonization in young chickens given feed supplemented with the growth promoting antibiotic avilamycin. Journal of veterinary pharmacology and therapeutics. 1988 Sep; 11(3):269-75. doi: 10.1111/j.1365-2885.1988.tb00152.x. [PMID: 3184267]
  • G Formica, C Giannone. Gas chromatographic determination of avilamycin total residues in pig tissues, fat, blood, feces, and urine. Journal - Association of Official Analytical Chemists. 1986 Sep; 69(5):763-6. doi: NULL. [PMID: 3771448]