Ataprost (BioDeep_00000176284)
human metabolite blood metabolite
代谢物信息卡片
化学式: C21H32O4 (348.23)
中文名称:
谱图信息:
最多检出来源 Mus musculus(blood) 75%
分子结构信息
SMILES: OC(C=CC1C(O)CC2CC(CC12)=CCCCC(O)=O)C1CCCC1
InChI: InChI=1S/C21H32O4/c22-19(15-6-2-3-7-15)10-9-17-18-12-14(5-1-4-8-21(24)25)11-16(18)13-20(17)23/h5,9-10,15-20,22-23H,1-4,6-8,11-13H2,(H,24,25)
描述信息
同义名列表
6 个代谢物同义名
5-[4-(3-cyclopentyl-3-hydroxyprop-1-en-1-yl)-5-hydroxy-hexahydro-1H-pentalen-2-ylidene]pentanoic acid; 5-[4-(3-cyclopentyl-3-hydroxyprop-1-en-1-yl)-5-hydroxy-octahydropentalen-2-ylidene]pentanoic acid; 5-[4-(3-Cyclopentyl-3-hydroxyprop-1-en-1-yl)-5-hydroxy-octahydropentalen-2-ylidene]pentanoate; Ataprost, 3as-(3aalpha,4alpha(1E,3R*),5beta,6aalpha)-isomer; 15-Cyclopentyl-omega-pentanor-5(e)-carbacyclin; Ataprost
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- S Zushi, Y Shinomura, T Kiyohara, T Minami, M Sugimachi, Y Higashimoto, S Kanayama, Y Matsuzawa. Role of prostaglandins in intestinal epithelial restitution stimulated by growth factors.
The American journal of physiology.
1996 May; 270(5 Pt 1):G757-62. doi:
10.1152/ajpgi.1996.270.5.g757. [PMID: 8967486] - H Nakano, M Monden, K Umeshita, M Murata, H Miyoshi, T Kanai, M Gotoh, T Mori. Cytoprotective effect of prostaglandin I2 analogues on superoxide-induced hepatocyte injury.
Surgery.
1994 Nov; 116(5):883-9. doi:
. [PMID: 7940193] - S Goto, Y I Kim, Y Kodama, T Kai, K Kawano, L Delriviere, S V Lynch, N Kamada, M Kobayashi. The effect of a prostaglandin I2 analogue (OP-41483) on energy metabolism in liver preservation and its relation to lipid peroxidative reperfusion injury in rats.
Cryobiology.
1993 Oct; 30(5):459-65. doi:
10.1006/cryo.1993.1046. [PMID: 8252913] - R Nishiyama, S Nakamura, S Suzuki, S Baba. Platelet-activating factor in hepatic ischemia/reperfusion injury. The effects of a PAF antagonist combined with a prostaglandin I2 analogue.
Transplantation.
1993 Jun; 55(6):1261-5. doi:
10.1097/00007890-199306000-00010. [PMID: 8516812] - R Matsuo. [Experimental study on protective effect of prostaglandin I2 derivative (OP-41483) on damage of warm ischemic kidney].
Nihon Hinyokika Gakkai zasshi. The japanese journal of urology.
1993 May; 84(5):857-65. doi:
10.5980/jpnjurol1989.84.857. [PMID: 8320891] - K Takeuchi. [Reperfusion injury after heart-lung transplantation--OP41483-alpha-CD (prostaglandin I2 analogue) as a preventive for the reperfusion injury, especially the oxygen derived free radicals].
[Zasshi] [Journal]. Nihon Kyobu Geka Gakkai.
1992 Feb; 40(2):225-34. doi:
NULL. [PMID: 1593162] - I Ono, T Ohura, K Azami, H Ogino, S Sasaki, M Murazumi. The effects of drugs on the arachidonate cascade in experimentally burned rabbits.
The Journal of burn care & rehabilitation.
1989 Jul; 10(4):314-20. doi:
10.1097/00004630-198907000-00005. [PMID: 2507549] - M Tobimatsu, Y Ueda, S Saito, T Tsumagari, K Konomi. Effects of a stable prostacyclin analog on experimental ischemic acute renal failure.
Annals of surgery.
1988 Jul; 208(1):65-70. doi:
10.1097/00000658-198807000-00009. [PMID: 3291800] - S Teraoka, K Takahashi, H Toma, T Sanaka, Y Yamaguchi, K Tanabe, H Sato, H Kawaguchi, S Oba, I Nakajima. Application of prostacyclin analogue and thromboxane synthetase inhibitor to chronic vascular rejection after kidney transplantation.
Transplantation proceedings.
1987 Oct; 19(5):3664-8. doi:
NULL. [PMID: 3313883] - S Teraoka, S Oba, K Takahashi, T Yagisawa, Y Yamaguchi, T Sanaka, K Tanabe, T Kawai, S Fuchinoue, H Honda. Therapeutic effect of antiplatelet agents on obstructive vascular lesions after kidney transplantation with cyclosporine.
Transplantation proceedings.
1987 Aug; 19(4 Suppl 5):77-81. doi:
NULL. [PMID: 3303573] - T Takahama, F Kanai, M Hiraishi, K Onishi, Z Yamazaki, A Furuse, K Asano, T Yoshitake. Comparative study of anticoagulation therapy with an LVAD system.
ASAIO transactions.
1987 Jul; 33(3):227-34. doi:
NULL. [PMID: 3118913] - M Tobimatsu, Y Ueda, K Toyoda, S Saito, K Konomi. Effect of a stable prostacyclin analogue on canine renal allograft rejection.
Annals of surgery.
1987 Feb; 205(2):199-202. doi:
10.1097/00000658-198702000-00016. [PMID: 3545109] - I Ono, T Ohura, K Azami, M Hoshi, T Hasegawa, M Tsutsumi. The effect of drugs which affect the arachidonate cascade in burned rabbits.
Burns, including thermal injury.
1986 Dec; 12(8):572-7. doi:
10.1016/0305-4179(86)90008-2. [PMID: 3136865] - H Soejima, Y Ayano, M Yoshida, J Machida, K Ikegami. [The effects of PGI2 and PGI2 analogue (OP41483) on acute renal ischemia in rabbits].
Nihon Jinzo Gakkai shi.
1986 Feb; 28(2):163-7. doi:
NULL. [PMID: 3525914] - Y Yui, Y Takatsu, R Hattori, C Kawai, Y Osaki, T Yohida. A new stable prostacyclin analogue OP41483 (15-cyclopentyl-omega-pentanor-5(E)-carbacyclin).
Japanese circulation journal.
1985 Jun; 49(6):571-5. doi:
10.1253/jcj.49.571. [PMID: 3897597] - I Ono, T Ohura, K Azami, M Hoshi, T Hasegawa. The effect of a prostaglandin I2 analogue (OP-41483) on renal function in burned rabbits.
Burns, including thermal injury.
1985 Jun; 11(5):320-9. doi:
10.1016/0305-4179(85)90094-4. [PMID: 3896419]
