Asialo GM1 (BioDeep_00000176255)

   

human metabolite blood metabolite


代谢物信息卡片


N-[1-({5-[(5-{[3-acetamido-5-hydroxy-6-(hydroxymethyl)-4-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxan-2-yl]oxy}-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl)oxy]-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl}oxy)-3-hydroxyoctadec-4-en-2-yl]octadecanamide

化学式: C62H114N2O23 (1254.7811974)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCCCCCCCCCCCCCCCC(=O)NC(COC1OC(CO)C(OC2OC(CO)C(OC3OC(CO)C(O)C(OC4OC(CO)C(O)C(O)C4O)C3NC(C)=O)C(O)C2O)C(O)C1O)C(O)C=CCCCCCCCCCCCCC
InChI: InChI=1S/C62H114N2O23/c1-4-6-8-10-12-14-16-18-19-21-23-25-27-29-31-33-46(71)64-40(41(70)32-30-28-26-24-22-20-17-15-13-11-9-7-5-2)38-80-60-54(78)51(75)57(44(36-67)83-60)86-62-55(79)52(76)56(45(37-68)84-62)85-59-47(63-39(3)69)58(49(73)43(35-66)81-59)87-61-53(77)50(74)48(72)42(34-65)82-61/h30,32,40-45,47-62,65-68,70,72-79H,4-29,31,33-38H2,1-3H3,(H,63,69)(H,64,71)



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

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代谢反应

0 个相关的代谢反应过程信息。

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BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

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1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Pankaj D Patil, Yuchen Jin, Yan-Yeung Luk. Chemical control over Asialo-GM1: A dual ligand for pili and Lectin A that activates swarming motility and facilitates adherence of Pseudomonas aeruginosa. Colloids and surfaces. B, Biointerfaces. 2022 Jul; 215(?):112478. doi: 10.1016/j.colsurfb.2022.112478. [PMID: 35390596]
  • Elena Chiricozzi, Erika Di Biase, Giulia Lunghi, Maria Fazzari, Nicoletta Loberto, Massimo Aureli, Laura Mauri, Sandro Sonnino. Turning the spotlight on the oligosaccharide chain of GM1 ganglioside. Glycoconjugate journal. 2021 02; 38(1):101-117. doi: 10.1007/s10719-021-09974-y. [PMID: 33620588]
  • Yuki Fujii, Marco Gerdol, Sarkar M A Kawsar, Imtiaj Hasan, Francesca Spazzali, Tatsusada Yoshida, Yukiko Ogawa, Sultana Rajia, Kenichi Kamata, Yasuhiro Koide, Shigeki Sugawara, Masahiro Hosono, Jeremy R H Tame, Hideaki Fujita, Alberto Pallavicini, Yasuhiro Ozeki. A GM1b/asialo-GM1 oligosaccharide-binding R-type lectin from purplish bifurcate mussels Mytilisepta virgata and its effect on MAP kinases. The FEBS journal. 2020 06; 287(12):2612-2630. doi: 10.1111/febs.15154. [PMID: 31769916]
  • Pablo M Rodi, Bruno Maggio, Luis A Bagatolli. Direct visualization of the lateral structure of giant vesicles composed of pseudo-binary mixtures of sulfatide, asialo-GM1 and GM1 with POPC. Biochimica et biophysica acta. Biomembranes. 2018 Feb; 1860(2):544-555. doi: 10.1016/j.bbamem.2017.10.022. [PMID: 29106974]
  • Osk U U Anuforo, Stefania P Bjarnarson, Hulda S Jonasdottir, Martin Giera, Ingibjorg Hardardottir, Jona Freysdottir. Natural killer cells play an essential role in resolution of antigen-induced inflammation in mice. Molecular immunology. 2018 01; 93(?):1-8. doi: 10.1016/j.molimm.2017.10.019. [PMID: 29112834]
  • Francisco Victorino, Dorothy K Sojka, Kelley S Brodsky, Eoin N McNamee, Joanne C Masterson, Dirk Homann, Wayne M Yokoyama, Holger K Eltzschig, Eric T Clambey. Tissue-Resident NK Cells Mediate Ischemic Kidney Injury and Are Not Depleted by Anti-Asialo-GM1 Antibody. Journal of immunology (Baltimore, Md. : 1950). 2015 Nov; 195(10):4973-85. doi: 10.4049/jimmunol.1500651. [PMID: 26453755]
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  • Galya Staneva, Nicolas Puff, Michel Seigneuret, Hélène Conjeaud, Miglena I Angelova. Segregative clustering of Lo and Ld membrane microdomains induced by local pH gradients in GM1-containing giant vesicles: a lipid model for cellular polarization. Langmuir : the ACS journal of surfaces and colloids. 2012 Nov; 28(47):16327-37. doi: 10.1021/la3031107. [PMID: 23121205]
  • Masao Iwamori, Yuriko Iwamori, Shigeki Adachi, Taisei Nomura. Excretion into feces of asialo GM1 in the murine digestive tract and Lactobacillus johnsonii exhibiting binding ability toward asialo GM1. A possible role of epithelial glycolipids in the discharge of intestinal bacteria. Glycoconjugate journal. 2011 Jan; 28(1):21-30. doi: 10.1007/s10719-010-9320-3. [PMID: 21174147]
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  • S Cossy Isasi, A R Fernandez, P Paglini, D H Bronia. GM1 ganglioside induced myocardial restoration and survival of mice with experimental Chagas' disease. Acta tropica. 1999 Oct; 73(3):295-302. doi: 10.1016/s0001-706x(99)00030-3. [PMID: 10546847]
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