Apronal (BioDeep_00000176158)

   

human metabolite blood metabolite


代谢物信息卡片


[2-(propan-2-yl)pent-4-enoyl]urea

化学式: C9H16N2O2 (184.12117160000003)
中文名称: 丙戊酰脲
谱图信息: 最多检出来源 Homo sapiens(blood) 98.72%

分子结构信息

SMILES: CC(C)C(CC=C)C(=O)NC(=O)N
InChI: InChI=1S/C9H16N2O2/c1-4-5-7(6(2)3)8(12)11-9(10)13/h4,6-7H,1,5H2,2-3H3,(H3,10,11,12,13)

描述信息

N - Nervous system > N05 - Psycholeptics > N05C - Hypnotics and sedatives

同义名列表

7 个代谢物同义名

[2-(propan-2-yl)pent-4-enoyl]urea; (2-isopropylpent-4-enoyl)urea; Allylisopropylacetylcarbamide; Allylisopropylacetylurea; Apronalide; Sedormid; Apronal



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Keiko Kudo, Akiko Kiyoshima, Yukio Ohtsuka, Noriaki Ikeda. Simultaneous determination of bromvalerylurea and allylisopropylacetylurea in human blood and urine by gas chromatography-mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2003 Jul; 791(1-2):171-7. doi: 10.1016/s1570-0232(03)00219-8. [PMID: 12798177]
  • F Moriya, Y Hashimoto. Postmortem diffusion of drugs from the bladder into femoral venous blood. Forensic science international. 2001 Dec; 123(2-3):248-53. doi: 10.1016/s0379-0738(01)00530-8. [PMID: 11728758]
  • T Takayasu, J Nishigami, T Ohshima, Z Lin, T Kondo, T Nakaya, T Sawaguchi, T Nagano. [A fatal case due to intoxication with seven drugs detected by GC-MS and TDx methods]. Nihon hoigaku zasshi = The Japanese journal of legal medicine. 1993 Feb; 47(1):63-71. doi: . [PMID: 8315862]
  • T Kumazawa, H Seno, O Suzuki. Rapid isolation with Sep-Pak C18 cartridges and wide-bore capillary gas chromatography of bromisovalum. Journal of analytical toxicology. 1992 May; 16(3):163-5. doi: 10.1093/jat/16.3.163. [PMID: 1522708]
  • H Miyauchi, K Ameno, C Fuke, S Ameno, I Ijiri. Simultaneous determination of bromvalerylurea, bromodiethylacetylurea, and allylisopropylacetylurea in serum and urine by high-performance liquid chromatography with a multiwavelength UV detector and thin-layer chromatography. Journal of analytical toxicology. 1991 May; 15(3):123-5. doi: 10.1093/jat/15.3.123. [PMID: 1682528]
  • T Higashi, F Kawamata, M Dogen. Biosynthesis of rat kidney catalase. Double-labeling by [14C]leucine and delta-amino[3H]levulinic acid. Journal of biochemistry. 1976 Aug; 80(2):259-65. doi: 10.1093/oxfordjournals.jbchem.a131272. [PMID: 826520]
  • G Rentsch, A Johnston. The effect of prolonged administration of allylisopropylacetylurea to rats on cytochrome P-450 and other liver haemoproteins. Xenobiotica; the fate of foreign compounds in biological systems. 1976 Mar; 6(3):151-7. doi: 10.3109/00498257609151625. [PMID: 1274379]
  • P E BROCKMAN, C H GRAY. Crystalline porphobilinogen from urine of rabbits treated with sedormid. The Biochemical journal. 1953 Jun; 54(3):xxi-xxii. doi: NULL. [PMID: 13058942]
  • V GRIFONI, A VOLTA, C VANACORE. [Demonstration of the thrombocytolytic activity of plasma during purpura caused by sedormid]. Minerva medica. 1952 Dec; 43(99):1305-12. doi: NULL. [PMID: 13036748]