Andromedol (BioDeep_00000176052)

   

human metabolite blood metabolite natural product


代谢物信息卡片


5,5,9,14-tetramethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁸]hexadecane-3,4,6,9,14,16-hexol

化学式: C20H34O6 (370.2355)
中文名称: 木藜芦毒素1/2乙酸加成化合物
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1(C(CC2C1(C(CC34CC(C(C3O)CCC4C2(C)O)(C)O)O)O)O)C
InChI: InChI=1S/C20H34O6/c1-16(2)13(21)7-12-18(4,25)11-6-5-10-15(23)19(11,9-17(10,3)24)8-14(22)20(12,16)26/h10-15,21-26H,5-9H2,1-4H3

描述信息

同义名列表

6 个代谢物同义名

5,5,9,14-tetramethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁸]hexadecane-3,4,6,9,14,16-hexol; Grayanotoxane-3,5,6,10,14,16-hexol,(3b,6b,14R)-; 10-Epi-grayanotoxin III; grayanotoxin III; Andromedol; GTX-III



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

23 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Yuanyuan Feng, Hanqi Zhang, Biao Gao, Guijuan Zheng, Suqin Zha, Guangmin Yao. Highly oxygenated grayanane diterpenoids with structural diversity from the flowers of Rhododendron dauricum and their analgesic activities. Bioorganic chemistry. 2023 03; 132(?):106374. doi: 10.1016/j.bioorg.2023.106374. [PMID: 36682149]
  • Züleyha Doğanyiğit, Sibel Silici, Abdullah Demirtaş, Ertuğrul Kaya, Emin Kaymak. Determination of histological, immunohistochemical and biochemical effects of acute and chronic grayanotoxin III administration in different doses in rats. Environmental science and pollution research international. 2019 Jan; 26(2):1323-1335. doi: 10.1007/s11356-018-3700-9. [PMID: 30426365]
  • Hong Lak Choi, Kyung Hye Park, Jung Soo Park, Hye Young Choi, Hoon Kim, Sun Moon Kim. Relationship between blood toxin level and clinical features in patients with grayanotoxin poisoning - six clinical cases. Clinical toxicology (Philadelphia, Pa.). 2017 Nov; 55(9):991-995. doi: 10.1080/15563650.2017.1331448. [PMID: 28594250]
  • Silici Sibel, Yonar M Enis, Sahin Hüseyin, Atayoğlu A Timucin, Ozkok Duran. Analysis of grayanatoxin in Rhododendron honey and effect on antioxidant parameters in rats. Journal of ethnopharmacology. 2014 Oct; 156(?):155-61. doi: 10.1016/j.jep.2014.08.027. [PMID: 25193682]
  • Arzum Bahar Kurtoglu, Recep Yavuz, Gulsun Akdemir Evrendilek. Characterisation and fate of grayanatoxins in mad honey produced from Rhododendron ponticum nectar. Food chemistry. 2014 Oct; 161(?):47-52. doi: 10.1016/j.foodchem.2014.03.127. [PMID: 24837920]
  • Rupert L Hough, Colin Crews, Duncan White, Malcolm Driffield, Colin D Campbell, Charlotte Maltin. Degradation of yew, ragwort and rhododendron toxins during composting. The Science of the total environment. 2010 Sep; 408(19):4128-37. doi: 10.1016/j.scitotenv.2010.05.024. [PMID: 20579691]
  • K H Plumlee, W G VanAlstine, J M Sullivan. Japanese pieris toxicosis of goats. Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc. 1992 Jul; 4(3):363-4. doi: 10.1177/104063879200400330. [PMID: 1515506]
  • R P Wilson, P L Fowlkes. Activity of glutamine synthetase in channel catfish tissues determined by an improved tissue assay method. Comparative biochemistry and physiology. B, Comparative biochemistry. 1976; 54(3):365-8. doi: 10.1016/0305-0491(76)90258-3. [PMID: 6197]