Amidoxime (BioDeep_00000175970)

   

human metabolite blood metabolite


代谢物信息卡片


N-hydroxy-4-{5-[4-(N-hydroxycarbamimidoyl)phenyl]furan-2-yl}benzene-1-carboximidamide

化学式: C18H16N4O3 (336.12223459999996)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(blood) 83.33%

分子结构信息

SMILES: C1=CC(=CC=C1C2=CC=C(O2)C3=CC=C(C=C3)C(=NO)N)C(=NO)N
InChI: InChI=1S/C18H16N4O3/c19-17(21-23)13-5-1-11(2-6-13)15-9-10-16(25-15)12-3-7-14(8-4-12)18(20)22-24/h1-10,23-24H,(H2,19,21)(H2,20,22)

描述信息

同义名列表

3 个代谢物同义名

N-hydroxy-4-{5-[4-(N-hydroxycarbamimidoyl)phenyl]furan-2-yl}benzene-1-carboximidamide; N-hydroxy-4-{5-[4-(N-hydroxycarbamimidoyl)phenyl]furan-2-yl}benzenecarboximidamide; Amidoxime



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Michel A Struwe, Axel J Scheidig, Bernd Clement. The mitochondrial amidoxime reducing component (mARC) - from prodrug-activation mechanism to drug-metabolising enzyme and onwards to drug target. The Journal of biological chemistry. 2023 Sep; ?(?):105306. doi: 10.1016/j.jbc.2023.105306. [PMID: 37778733]
  • Bernd Clement, Michel A Struwe. The History of mARC. Molecules (Basel, Switzerland). 2023 Jun; 28(12):. doi: 10.3390/molecules28124713. [PMID: 37375270]
  • Di Zhang, Lijie Liu, Bing Zhao, Xiangxue Wang, Hongwei Pang, Shujun Yu. Highly efficient extraction of uranium from seawater by polyamide and amidoxime co-functionalized MXene. Environmental pollution (Barking, Essex : 1987). 2023 Jan; 317(?):120826. doi: 10.1016/j.envpol.2022.120826. [PMID: 36493939]
  • Ludmila Maiber, Anna Koprivova, Daniel Bender, Stanislav Kopriva, Katrin Fischer-Schrader. Characterization of the amidoxime reducing components ARC1 and ARC2 from Arabidopsis thaliana. The FEBS journal. 2022 09; 289(18):5656-5669. doi: 10.1111/febs.16450. [PMID: 35366369]
  • Jan Samsonowicz-Górski, Anna Brodzka, Ryszard Ostaszewski, Dominik Koszelewski. Screening for amidoxime reductases in plant roots and Saccharomyces cerevisiae - Development of biocatalytic method for chemoselective amidine synthesis. Bioorganic chemistry. 2022 07; 124(?):105815. doi: 10.1016/j.bioorg.2022.105815. [PMID: 35512419]
  • Long-Fei Ren, Kai Chen, Xiaofan Zhang, Yubo Xu, Lei Chen, Jiahui Shao, Yiliang He. Effect of aniline and antimony on anaerobic-anoxic-oxic system with novel amidoxime-modified polyacrylonitrile adsorbent for wastewater treatment. Bioresource technology. 2022 May; 351(?):127082. doi: 10.1016/j.biortech.2022.127082. [PMID: 35358677]
  • Deepak Ahire, Abdul Basit, Lisa J Christopher, Ramaswamy Iyer, J Steven Leeder, Bhagwat Prasad. Interindividual Variability and Differential Tissue Abundance of Mitochondrial Amidoxime Reducing Component Enzymes in Humans. Drug metabolism and disposition: the biological fate of chemicals. 2022 03; 50(3):191-196. doi: 10.1124/dmd.121.000805. [PMID: 34949674]
  • Leila Farzin, Sodeh Sadjadi, Mojtaba Shamsipur, Shahab Sheibani, Mohammad Hasan Mousazadeh. Employing AgNPs doped amidoxime-modified polyacrylonitrile (PAN-oxime) nanofibers for target induced strand displacement-based electrochemical aptasensing of CA125 in ovarian cancer patients. Materials science & engineering. C, Materials for biological applications. 2019 Apr; 97(?):679-687. doi: 10.1016/j.msec.2018.12.108. [PMID: 30678956]
  • Anna Parus, Grzegorz Framski. Impact of O-alkyl-pyridineamidoximes on the soil environment. The Science of the total environment. 2018 Dec; 643(?):1278-1284. doi: 10.1016/j.scitotenv.2018.06.266. [PMID: 30189544]
  • Yubing Sun, Songhua Lu, Xiangxue Wang, Chao Xu, Jiaxing Li, Changlun Chen, Jing Chen, Tasawar Hayat, Ahmed Alsaedi, Njud S Alharbi, Xiangke Wang. Plasma-Facilitated Synthesis of Amidoxime/Carbon Nanofiber Hybrids for Effective Enrichment of 238U(VI) and 241Am(III). Environmental science & technology. 2017 Nov; 51(21):12274-12282. doi: 10.1021/acs.est.7b02745. [PMID: 29017009]
  • Hoai-Nam Truong, Christian Meyer. A new NO ledge in Chlamydomonas: when the old nitrate reductase meets amidoxime reducing component to produce nitric oxide. Plant, cell & environment. 2016 10; 39(10):2095-6. doi: 10.1111/pce.12803. [PMID: 27435600]
  • Birte Plitzko, Antje Havemeyer, Bettina Bork, Florian Bittner, Ralf Mendel, Bernd Clement. Defining the Role of the NADH-Cytochrome-b5 Reductase 3 in the Mitochondrial Amidoxime Reducing Component Enzyme System. Drug metabolism and disposition: the biological fate of chemicals. 2016 10; 44(10):1617-21. doi: 10.1124/dmd.116.071845. [PMID: 27469001]