2,2-Dimethyl-5-hydroxy-1-pyrrolidinyloxy (BioDeep_00000175613)
human metabolite blood metabolite
代谢物信息卡片
化学式: C6H12NO2 (130.0868)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 76%
分子结构信息
SMILES: CC1(C)CCC(O)N1[O]
InChI: InChI=1S/C6H12NO2/c1-6(2)4-3-5(8)7(6)9/h5,8H,3-4H2,1-2H3
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
亚细胞结构定位 | 关联基因列表 |
---|
文献列表
- Yasumasa Okazaki, Hiromasa Tanaka, Ken-Ichiro Matsumoto, Masaru Hori, Shinya Toyokuni. Non-thermal plasma-induced DMPO-OH yields hydrogen peroxide.
Archives of biochemistry and biophysics.
2021 07; 705(?):108901. doi:
10.1016/j.abb.2021.108901
. [PMID: 33964248] - Wan-Ook Ji, Min-Ho Lee, Gon-Ho Kim, Eun-Hee Kim. Quantitation of the ROS production in plasma and radiation treatments of biotargets.
Scientific reports.
2019 12; 9(1):19837. doi:
10.1038/s41598-019-56160-0
. [PMID: 31882663] - Javiera Cervini-Silva, Antonio Nieto-Camacho, Virginia Gomez-Vidales, María Teresa Ramírez-Apán. Oxidative stress induced by arsenopyrite and the role of desferrioxamine-B as radical scavenger.
Chemosphere.
2013 Feb; 90(6):1779-84. doi:
10.1016/j.chemosphere.2012.08.005
. [PMID: 22955046] - Yi Sun, Shuang Yu, Peng Sun, Haiyan Wu, Weidong Zhu, Wei Liu, Jue Zhang, Jing Fang, Ruoyu Li. Inactivation of Candida biofilms by non-thermal plasma and its enhancement for fungistatic effect of antifungal drugs.
PloS one.
2012; 7(7):e40629. doi:
10.1371/journal.pone.0040629
. [PMID: 22808213] - T Watanabe, S Owada, H P Kobayashi, H Kawakami, S Nagaoka, E Murakami, A Ishiuchi, T Enomoto, Y Jinnouchi, J Sakurai, N Tobe, S Koizumi, T Shimamura, T Asakura, H Nakano, T Otsubo. Protective effects of MnM2Py4P and Mn-salen against small bowel ischemia/reperfusion injury in rats using an in vivo and an ex vivo electron paramagnetic resonance technique with a spin probe.
Transplantation proceedings.
2007 Dec; 39(10):3002-6. doi:
10.1016/j.transproceed.2007.08.091
. [PMID: 18089309] - J G Masilamoni, E P Jesudason, B'joe Baben, Charles E Jebaraj, S Dhandayuthapani, R Jayakumar. Molecular chaperone alpha-crystallin prevents detrimental effects of neuroinflammation.
Biochimica et biophysica acta.
2006 Mar; 1762(3):284-93. doi:
10.1016/j.bbadis.2005.11.007
. [PMID: 16443350] - Joana Martins, Leonor Almeida, João Laranjinha. Simultaneous production of superoxide radical and singlet oxygen by sulphonated chloroaluminum phthalocyanine incorporated in human low-density lipoproteins: implications for photodynamic therapy.
Photochemistry and photobiology.
2004 Sep; 80(2):267-73. doi:
10.1562/2004-03-26-ra-124
. [PMID: 15362945] - Kazunori Anzai, Tetsuya Aikawa, Yoshiko Furukawa, Yoshikazu Matsushima, Shiro Urano, Toshihiko Ozawa. ESR measurement of rapid penetration of DMPO and DEPMPO spin traps through lipid bilayer membranes.
Archives of biochemistry and biophysics.
2003 Jul; 415(2):251-6. doi:
10.1016/s0003-9861(03)00260-1
. [PMID: 12831849] - I E Blasig, K Mertsch, R F Haseloff. Nitronyl nitroxides, a novel group of protective agents against oxidative stress in endothelial cells forming the blood-brain barrier.
Neuropharmacology.
2002 Nov; 43(6):1006-14. doi:
10.1016/s0028-3908(02)00180-6
. [PMID: 12423670] - Nobuyasu Sekiya, Hirozo Goto, Kenji Tazawa, Shoko Oida, Yutaka Shimada, Katsutoshi Terasawa. Keishi-bukuryo-gan preserves the endothelium dependent relaxation of thoracic aorta in cholesterol-fed rabbit by limiting superoxide generation.
Phytotherapy research : PTR.
2002 Sep; 16(6):524-8. doi:
10.1002/ptr.945
. [PMID: 12237808] - I T Mak, A M Komarov, J H Kramer, W B Weglicki. Protective mechanisms of Mg-gluconate against oxidative endothelial cytotoxicity.
Cellular and molecular biology (Noisy-le-Grand, France).
2000 Dec; 46(8):1337-44. doi:
. [PMID: 11156479]
- L Y Zang, G Cosma, H Gardner, X Shi, V Castranova, V Vallyathan. Effect of antioxidant protection by p-coumaric acid on low-density lipoprotein cholesterol oxidation.
American journal of physiology. Cell physiology.
2000 Oct; 279(4):C954-60. doi:
10.1152/ajpcell.2000.279.4.c954
. [PMID: 11003575] - L Gille, H Nohl. The existence of a lysosomal redox chain and the role of ubiquinone.
Archives of biochemistry and biophysics.
2000 Mar; 375(2):347-54. doi:
10.1006/abbi.1999.1649
. [PMID: 10700391] - Y M Yoo, K M Kim, S S Kim, J A Han, H Z Lea, Y M Kim. Hemoglobin toxicity in experimental bacterial peritonitis is due to production of reactive oxygen species.
Clinical and diagnostic laboratory immunology.
1999 Nov; 6(6):938-45. doi:
10.1128/cdli.6.6.938-945.1999
. [PMID: 10548590] - M Gómez-Vargas, S Nishibayashi-Asanuma, M Asanuma, Y Kondo, E Iwata, N Ogawa. Pergolide scavenges both hydroxyl and nitric oxide free radicals in vitro and inhibits lipid peroxidation in different regions of the rat brain.
Brain research.
1998 Apr; 790(1-2):202-8. doi:
10.1016/s0006-8993(97)01521-7
. [PMID: 9593894] - H Masaki, Y Okano, H Sakurai. Generation of active oxygen species from advanced glycation end-products (AGE) under ultraviolet light A (UVA) irradiation.
Biochemical and biophysical research communications.
1997 Jun; 235(2):306-10. doi:
10.1006/bbrc.1997.6780
. [PMID: 9199187] - S Pietri, E Maurelli, K Drieu, M Culcasi. Cardioprotective and anti-oxidant effects of the terpenoid constituents of Ginkgo biloba extract (EGb 761).
Journal of molecular and cellular cardiology.
1997 Feb; 29(2):733-42. doi:
10.1006/jmcc.1996.0316
. [PMID: 9140830] - T Utsumi, M Okuma, T Kanno, Y Takehara, T Yoshioka, Y Fujita, A A Horton, K Utsumi. Effect of the antiretroviral agent hypericin on rat liver mitochondria.
Biochemical pharmacology.
1995 Aug; 50(5):655-62. doi:
10.1016/0006-2952(95)00143-n
. [PMID: 7669068] - K Sai, S Uchiyama, Y Ohno, R Hasegawa, Y Kurokawa. Generation of active oxygen species in vitro by the interaction of potassium bromate with rat kidney cell.
Carcinogenesis.
1992 Mar; 13(3):333-9. doi:
10.1093/carcin/13.3.333
. [PMID: 1547521] - A C Povey, V L Wilson, J L Zweier, P Kuppusamy, I K O'Neill, C C Harris. Detection by 32P-postlabelling of DNA adducts induced by free radicals and unsaturated aldehydes formed during the aerobic decomposition of fecapentaene-12.
Carcinogenesis.
1992 Mar; 13(3):395-401. doi:
10.1093/carcin/13.3.395
. [PMID: 1547529] - Y Adachi, G Wakisaka, T Yamamoto. Salycylamide glucuronide formation in liver disease and its change by drugs.
Gastroenterologia Japonica.
1975; 10(2):120-31. doi:
10.1007/bf02774839
. [PMID: 10219]