CC(C)=CCCC(C)=CCc1c(O)ccc(C(=O)C=Cc2ccc(O)cc2)c1O (BioDeep_00000175585)

   

human metabolite blood metabolite


代谢物信息卡片


1-[3-(3,7-dimethylocta-2,6-dien-1-yl)-2,4-dihydroxyphenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one

化学式: C25H28O4 (392.19874880000003)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C)=CCCC(C)=CCC1=C(O)C=CC(C(=O)C=CC2=CC=C(O)C=C2)=C1O
InChI: InChI=1S/C25H28O4/c1-17(2)5-4-6-18(3)7-13-21-24(28)16-14-22(25(21)29)23(27)15-10-19-8-11-20(26)12-9-19/h5,7-12,14-16,26,28-29H,4,6,13H2,1-3H3

描述信息

同义名列表

2 个代谢物同义名

1-[3-(3,7-dimethylocta-2,6-dien-1-yl)-2,4-dihydroxyphenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one; CC(C)=CCCC(C)=CCc1c(O)ccc(C(=O)C=Cc2ccc(O)cc2)c1O



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Toshiyuki Nakamura, Takahiro Tokushima, Kyuichi Kawabata, Norio Yamamoto, Masaaki Miyamoto, Hitoshi Ashida. Absorption and metabolism of 4-hydroxyderricin and xanthoangelol after oral administration of Angelica keiskei (Ashitaba) extract in mice. Archives of biochemistry and biophysics. 2012 May; 521(1-2):71-6. doi: 10.1016/j.abb.2012.03.013. [PMID: 22452965]
  • Hiromu Ohnogi, Yoko Kudo, Kenichi Tahara, Katsumi Sugiyama, Tatsuji Enoki, Shoko Hayami, Hiroaki Sagawa, Yuko Tanimura, Wataru Aoi, Yuji Naito, Ikunoshin Kato, Toshikazu Yoshikawa. Six new chalcones from Angelica keiskei inducing adiponectin production in 3T3-L1 adipocytes. Bioscience, biotechnology, and biochemistry. 2012; 76(5):961-6. doi: 10.1271/bbb.110976. [PMID: 22738967]
  • Naoki Ohkura, Yoshitaka Nakakuki, Masahiko Taniguchi, Shiho Kanai, Akiko Nakayama, Katsunori Ohnishi, Toshiyuki Sakata, Tomoyoshi Nohira, Juzo Matsuda, Kimiye Baba, Gen-Ichi Atsumi. Xanthoangelols isolated from Angelica keiskei inhibit inflammatory-induced plasminogen activator inhibitor 1 (PAI-1) production. BioFactors (Oxford, England). 2011 Nov; 37(6):455-61. doi: 10.1002/biof.187. [PMID: 22038782]
  • Kyuichi Kawabata, Keisuke Sawada, Kazunori Ikeda, Itsuko Fukuda, Kengo Kawasaki, Norio Yamamoto, Hitoshi Ashida. Prenylated chalcones 4-hydroxyderricin and xanthoangelol stimulate glucose uptake in skeletal muscle cells by inducing GLUT4 translocation. Molecular nutrition & food research. 2011 Mar; 55(3):467-75. doi: 10.1002/mnfr.201000267. [PMID: 20938990]
  • Ji Eun Shin, Eun Jin Choi, Qinglong Jin, Hong-Guang Jin, Eun-Rhan Woo. Chalcones isolated from Angelica keiskei and their inhibition of IL-6 production in TNF-α-stimulated MG-63 cell. Archives of pharmacal research. 2011 Mar; 34(3):437-42. doi: 10.1007/s12272-011-0311-0. [PMID: 21547675]
  • Song-Chwan Fang, Chin-Lin Hsu, Yu-Shen Yu, Gow-Chin Yen. Cytotoxic effects of new geranyl chalcone derivatives isolated from the leaves of Artocarpus communis in SW 872 human liposarcoma cells. Journal of agricultural and food chemistry. 2008 Oct; 56(19):8859-68. doi: 10.1021/jf8017436. [PMID: 18767861]
  • Nobuwa Aoki, Mai Muko, Emi Ohta, Shinji Ohta. C-geranylated chalcones from the stems of Angelica keiskei with superoxide-scavenging activity. Journal of natural products. 2008 Jul; 71(7):1308-10. doi: 10.1021/np800187f. [PMID: 18558745]
  • Kou Motani, Keiichi Tabata, Yumiko Kimura, Soichiro Okano, Yasuko Shibata, Yoshimitsu Abiko, Hisashi Nagai, Toshihiro Akihisa, Takashi Suzuki. Proteomic analysis of apoptosis induced by xanthoangelol, a major constituent of Angelica keiskei, in neuroblastoma. Biological & pharmaceutical bulletin. 2008 Apr; 31(4):618-26. doi: 10.1248/bpb.31.618. [PMID: 18379052]
  • Tatsuji Enoki, Hiromu Ohnogi, Kinuko Nagamine, Yoko Kudo, Katsumi Sugiyama, Masashige Tanabe, Eiji Kobayashi, Hiroaki Sagawa, Ikunoshin Kato. Antidiabetic activities of chalcones isolated from a Japanese Herb, Angelica keiskei. Journal of agricultural and food chemistry. 2007 Jul; 55(15):6013-7. doi: 10.1021/jf070720q. [PMID: 17583349]
  • Hiroshi Ogawa, Yukiko Okada, Toshinori Kamisako, Kimiye Baba. Beneficial effect of xanthoangelol, a chalcone compound from Angelica keiskei, on lipid metabolism in stroke-prone spontaneously hypertensive rats. Clinical and experimental pharmacology & physiology. 2007 Mar; 34(3):238-43. doi: 10.1111/j.1440-1681.2007.04578.x. [PMID: 17250645]
  • Masato Sugii, Mamoru Ohkita, Masahiko Taniguchi, Kimiye Baba, Yu Kawai, Chiyoko Tahara, Masanori Takaoka, Yasuo Matsumura. Xanthoangelol D isolated from the roots of Angelica keiskei inhibits endothelin-1 production through the suppression of nuclear factor-kappaB. Biological & pharmaceutical bulletin. 2005 Apr; 28(4):607-10. doi: 10.1248/bpb.28.607. [PMID: 15802795]
  • Lalith Jayasinghe, B A I S Balasooriya, W Chintha Padmini, Noriyuki Hara, Yoshinori Fujimoto. Geranyl chalcone derivatives with antifungal and radical scavenging properties from the leaves of Artocarpus nobilis. Phytochemistry. 2004 May; 65(9):1287-90. doi: 10.1016/j.phytochem.2004.03.033. [PMID: 15184014]
  • Yoshiyuki Kimura, Masahiko Taniguchi, Kimiye Baba. Antitumor and antimetastatic activities of 4-hydroxyderricin isolated from Angelica keiskei roots. Planta medica. 2004 Mar; 70(3):211-9. doi: 10.1055/s-2004-815537. [PMID: 15114497]
  • Yoshiyuki Kimura, Kimiye Baba. Antitumor and antimetastatic activities of Angelica keiskei roots, part 1: Isolation of an active substance, xanthoangelol. International journal of cancer. 2003 Sep; 106(3):429-37. doi: 10.1002/ijc.11256. [PMID: 12845685]
  • M Matsuura, Y Kimura, K Nakata, K Baba, H Okuda. Artery relaxation by chalcones isolated from the roots of Angelica keiskei. Planta medica. 2001 Apr; 67(3):230-5. doi: 10.1055/s-2001-12011. [PMID: 11345693]