But-2-enedial (BioDeep_00000175572)
human metabolite blood metabolite
代谢物信息卡片
2-butene-1,4-dial
化学式: C4H4O2 (84.0211284)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: O=CC=CC=O
InChI: InChI=1S/C4H4O2/c5-3-1-2-4-6/h1-4H
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
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Journal of dairy science.
2012 Aug; 95(8):4510-8. doi:
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Chinese journal of integrative medicine.
2012 Jul; 18(7):490-5. doi:
10.1007/s11655-012-1097-8. [PMID: 22772911] - Ming Duan, Hai-Long Feng, Li-Yan Wang, Dong Li, Qing-Wei Meng. Overexpression of thylakoidal ascorbate peroxidase shows enhanced resistance to chilling stress in tomato.
Journal of plant physiology.
2012 Jun; 169(9):867-77. doi:
10.1016/j.jplph.2012.02.012. [PMID: 22475501] - Chunchao Han, Jianyou Guo. Antibacterial and anti-inflammatory activity of traditional Chinese herb pairs, Angelica sinensis and Sophora flavescens.
Inflammation.
2012 Jun; 35(3):913-9. doi:
10.1007/s10753-011-9393-6. [PMID: 21976127] - Jicang Wang, Zijun Yang, Lin Lin, Zhanqin Zhao, Zongping Liu, Xuezhong Liu. Protective effect of naringenin against lead-induced oxidative stress in rats.
Biological trace element research.
2012 Jun; 146(3):354-9. doi:
10.1007/s12011-011-9268-6. [PMID: 22109809] - Qin Feng, Xuemei Li, Jinghua Peng, Xiaohua Duan, Qilin Fu, Yiyang Hu. [Effect of gypenosides on DMN-induced liver fibrosis in rats].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2012 Feb; 37(4):505-8. doi:
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Asian Pacific journal of cancer prevention : APJCP.
2012; 13(8):4107-12. doi:
10.7314/apjcp.2012.13.8.4107. [PMID: 23098525] - Xiu-Hua Zhang, Hong Lei, Ai-Jun Liu, Ying-Xin Zou, Fu-Ming Shen, Ding-Feng Su. Increased oxidative stress is responsible for severer cerebral infarction in stroke-prone spontaneously hypertensive rats.
CNS neuroscience & therapeutics.
2011 Dec; 17(6):590-8. doi:
10.1111/j.1755-5949.2011.00271.x. [PMID: 22117799] - Lisa A Peterson, Martin B Phillips, Ding Lu, Mathilde M Sullivan. Polyamines are traps for reactive intermediates in furan metabolism.
Chemical research in toxicology.
2011 Nov; 24(11):1924-36. doi:
10.1021/tx200273z. [PMID: 21842885] - Chun-chao Han, Hong Wei, Jianyou Guo. Anti-inflammatory effects of fermented and non-fermented Sophora flavescens: a comparative study.
BMC complementary and alternative medicine.
2011 Oct; 11(?):100. doi:
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Pharmaceutical biology.
2011 Aug; 49(8):815-20. doi:
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Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases.
2011 Aug; 29(8):589-92. doi:
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DNA research : an international journal for rapid publication of reports on genes and genomes.
2011 Apr; 18(2):77-92. doi:
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Cellular and molecular neurobiology.
2011 Jan; 31(1):73-82. doi:
10.1007/s10571-010-9555-3. [PMID: 20734129] - Simon Wan Chan, Peter C Dedon. The biological and metabolic fates of endogenous DNA damage products.
Journal of nucleic acids.
2010 Dec; 2010(?):929047. doi:
10.4061/2010/929047. [PMID: 21209721] - Jun Li, Huan Zhang, Gexiu Liu. [Research on anti-aging effect of mouse placenta cells transplantation].
Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi.
2010 Dec; 27(6):1312-6. doi:
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2010 Oct; 38(10):1698-706. doi:
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Cancer immunology, immunotherapy : CII.
2010 Sep; 59(9):1335-45. doi:
10.1007/s00262-010-0862-9. [PMID: 20473755] - Yan Jiang. [Effects of anthocyanins derived from Xinjiang black mulberry fruit on delaying aging].
Wei sheng yan jiu = Journal of hygiene research.
2010 Jul; 39(4):451-3. doi:
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International urology and nephrology.
2010 Jun; 42(2):401-8. doi:
10.1007/s11255-009-9610-5. [PMID: 19609708] - Hong-Yu Xu, Jun-En Sun, Zhen-Ming Lu, Xiao-Mei Zhang, Wen-Fang Dou, Zheng-Hong Xu. Beneficial effects of the ethanol extract from the dry matter of a culture broth of Inonotus obliquus in submerged culture on the antioxidant defence system and regeneration of pancreatic beta-cells in experimental diabetes in mice.
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2010 Apr; 24(6):542-53. doi:
10.1080/14786410902751009. [PMID: 20397104] - Jun Li, Yuan Zhang, Ge-Xiu Liu. [Anti-aging effect of transplantation of mouse fetus-derived mesenchymal stem cells].
Sheng li xue bao : [Acta physiologica Sinica].
2010 Feb; 62(1):79-85. doi:
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Journal of ethnopharmacology.
2010 Feb; 127(2):221-8. doi:
10.1016/j.jep.2009.11.017. [PMID: 19932162] - Ding Lu, Lisa A Peterson. Identification of furan metabolites derived from cysteine-cis-2-butene-1,4-dial-lysine cross-links.
Chemical research in toxicology.
2010 Jan; 23(1):142-51. doi:
10.1021/tx9003215. [PMID: 20043645] - Yu-Mei Zhang, Xue-Zhong Liu, Hao Lu, Li Mei, Zong-Ping Liu. Lipid peroxidation and ultrastructural modifications in brain after perinatal exposure to lead and/or cadmium in rat pups.
Biomedical and environmental sciences : BES.
2009 Oct; 22(5):423-9. doi:
10.1016/s0895-3988(10)60021-9. [PMID: 20163068] - Wen-li Cheng, Xiu-yin Wang, Zhen-you Jiang, Jing-qiang Pan, Jun Dong, Shao-song Kuang, Zi-liang Rao. [The immunomodulatory effects of sijunzi decoction and its disassembled prescription on D-galactose-induced aging mice].
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials.
2009 Sep; 32(9):1425-9. doi:
NULL. [PMID: 20034224] - Ding Lu, Mathilde M Sullivan, Martin B Phillips, Lisa A Peterson. Degraded protein adducts of cis-2-butene-1,4-dial are urinary and hepatocyte metabolites of furan.
Chemical research in toxicology.
2009 Jun; 22(6):997-1007. doi:
10.1021/tx800377v. [PMID: 19441776] - Tao Yang, Jingjing Wu, Changyuan Wang, Qi Liu, Xiaochi Ma, Jinyong Peng, Taiichi Kaku, Kexin Liu. Protective effect of JBP485 on concanavalin A-induced liver injury in mice.
The Journal of pharmacy and pharmacology.
2009 Jun; 61(6):767-74. doi:
10.1211/jpp.61.06.0009. [PMID: 19505367] - Li Liu, Wei Liu, Jinlan Song, Hongyao Yu, Yihe Jin, Kazunori Oami, Itaru Sato, Norimitsu Saito, Shuji Tsuda. A comparative study on oxidative damage and distributions of perfluorooctane sulfonate (PFOS) in mice at different postnatal developmental stages.
The Journal of toxicological sciences.
2009 Jun; 34(3):245-54. doi:
10.2131/jts.34.245. [PMID: 19483379] - Xiuli Chang, Chunfeng Shao, Qing Wu, Qiangen Wu, Min Huang, Zhijun Zhou. Pyrrolidine dithiocarbamate attenuates paraquat-induced lung injury in rats.
Journal of biomedicine & biotechnology.
2009; 2009(?):619487. doi:
10.1155/2009/619487. [PMID: 19639047] - Jun Li, Wei-jia Kong, Xue-yan Zhao, Yu-juan Hu. [Oxidative stress experimental model of rat with stria vascularis marginal cells injury induced by hydrogen peroxide in vitro].
Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery.
2008 Nov; 43(11):835-9. doi:
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Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases.
2008 Oct; 26(10):583-7. doi:
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Colloids and surfaces. B, Biointerfaces.
2008 Sep; 65(2):220-5. doi:
10.1016/j.colsurfb.2008.04.007. [PMID: 18502620] - R Soundravally, P Sankar, Z Bobby, S L Hoti. Oxidative stress in severe dengue viral infection: association of thrombocytopenia with lipid peroxidation.
Platelets.
2008 Sep; 19(6):447-54. doi:
10.1080/09537100802155284. [PMID: 18925513] - Wei Li, Xiu-Zhen Sun, Yun Liu. [The role of nuclear factor kappa B activation in immune-complex-induced acute lung injury in rabbits].
Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases.
2008 Aug; 31(8):611-3. doi:
NULL. [PMID: 19080410] - Dongmei Li, Chuntao Yuan, Yi Gong, Yufeng Huang, Xiaodong Han. The effects of methyl tert-butyl ether (MTBE) on the male rat reproductive system.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2008 Jul; 46(7):2402-8. doi:
10.1016/j.fct.2008.03.024. [PMID: 18467015] - Jun-En Sun, Zong-Hua Ao, Zhen-Ming Lu, Hong-Yu Xu, Xiao-Mei Zhang, Wen-Fang Dou, Zheng-Hong Xu. Antihyperglycemic and antilipidperoxidative effects of dry matter of culture broth of Inonotus obliquus in submerged culture on normal and alloxan-diabetes mice.
Journal of ethnopharmacology.
2008 Jun; 118(1):7-13. doi:
10.1016/j.jep.2008.02.030. [PMID: 18434051] - Bei-Bei Liang, Hua-Gang Liu, Jiu-Tao Cao. [Antitumor effect of polysaccharides from cactus pear fruit in S180-bearing mice].
Ai zheng = Aizheng = Chinese journal of cancer.
2008 Jun; 27(6):580-4. doi:
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Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences.
2008 05; 37(3):308-11. doi:
10.3785/j.issn.1008-9292.2008.03.017. [PMID: 18546537] - Hee-jin Jun, Kwang-Geun Lee, Yun-Kyung Lee, Gun-Jo Woo, Young Sig Park, Sung-Joon Lee. Correlation of urinary furan with plasma gamma-glutamyltranspeptidase levels in healthy men and women.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2008 May; 46(5):1753-9. doi:
10.1016/j.fct.2008.01.013. [PMID: 18295953] - Marco Kellert, Silvia Wagner, Ursula Lutz, Werner K Lutz. Biomarkers of furan exposure by metabolic profiling of rat urine with liquid chromatography-tandem mass spectrometry and principal component analysis.
Chemical research in toxicology.
2008 Mar; 21(3):761-8. doi:
10.1021/tx7004212. [PMID: 18269250] - Gang Wang, Bei Sun, Yue Gao, Qing Hui Meng, Hong Chi Jiang. An experimental study of emodin assisted early enteral nutrition for the treatment of severe acute pancreatitis.
Hepato-gastroenterology.
2008 Jan; 55(81):33-40. doi:
NULL. [PMID: 18507074] - Chunsheng Liu, Ke Yu, Xiongjie Shi, Jingxian Wang, Paul K S Lam, Rudolf S S Wu, Bingsheng Zhou. Induction of oxidative stress and apoptosis by PFOS and PFOA in primary cultured hepatocytes of freshwater tilapia (Oreochromis niloticus).
Aquatic toxicology (Amsterdam, Netherlands).
2007 May; 82(2):135-43. doi:
10.1016/j.aquatox.2007.02.006. [PMID: 17374408] - Gang Wang, Bei Sun, Yue Gao, Qing Hui Meng, Hong Chi Jiang. The effect of emodin-assisted early enteral nutrition on severe acute pancreatitis and secondary hepatic injury.
Mediators of inflammation.
2007; 2007(?):29638. doi:
10.1155/2007/29638. [PMID: 18288270] - Bei Zhou, Li-Jun Wu, Lin-Hao Li, Shin-ichi Tashiro, Satoshi Onodera, Fumiaki Uchiumi, Takashi Ikejima. Silibinin protects against isoproterenol-induced rat cardiac myocyte injury through mitochondrial pathway after up-regulation of SIRT1.
Journal of pharmacological sciences.
2006 Dec; 102(4):387-95. doi:
10.1254/jphs.fpj06005x. [PMID: 17170512] - Dong-Sheng Chi, Wen-Hua Ling, Jing Ma, Min Xia, Meng-Jun Hou, Qing Wang, Hui-Lian Zhu, Zhi-Hong Tang, Xiao-Ping Yu. [Study of the association between paraoxonase1 55 Met/Leu, paraoxonase2 148 Ala/Gly and manganese superoxide dismutase (MnSOD) 9 Ala/Val genetic polymorphisms and coronary heart disease].
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi.
2006 Sep; 27(9):808-13. doi:
NULL. [PMID: 17299970] - Lisa A Peterson, Meredith E Cummings, Jacqueline Y Chan, Choua C Vu, Brock A Matter. Identification of a cis-2-butene-1,4-dial-derived glutathione conjugate in the urine of furan-treated rats.
Chemical research in toxicology.
2006 Sep; 19(9):1138-41. doi:
10.1021/tx060111x. [PMID: 16978017] - Dong-sheng Chi, Wen-hua Ling, Jing Ma, Min Xia, Meng-jun Hou, Qing Wang, Hui-lian Zhu, Zhi-hong Tang, Xiao-ping Yu. [Relationship between paraoxonase 1 55 Met/Leu, paraoxonase 2 148 Ala/Gly genetic polymorphisms and coronary artery disease].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics.
2006 Jun; 23(3):289-93. doi:
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Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2006 Mar; 31(6):483-4, 521. doi:
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Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2006 Mar; 31(5):407-10. doi:
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Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials.
2006 Mar; 29(3):266-9. doi:
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Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2005 Oct; 30(20):1606-9. doi:
NULL. [PMID: 16422544] - Choua C Vu, Lisa A Peterson. Synthesis of a 2'-deoxyguanosine adduct of cis-2-butene-1,4-dial, a reactive metabolite of furan.
Chemical research in toxicology.
2005 Jun; 18(6):1012-7. doi:
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The American journal of Chinese medicine.
2005; 33(1):11-20. doi:
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Biochimica et biophysica acta.
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