1-Methyl-2-(2-thiophen-2-ylethenyl)-5,6-dihydro-4H-pyrimidine (BioDeep_00000175555)
human metabolite blood metabolite
代谢物信息卡片
1-methyl-2-[2-(thiophen-2-yl)ethenyl]-1,4,5,6-tetrahydropyrimidine
化学式: C11H14N2S (206.0878)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 83.33%
分子结构信息
SMILES: CN1CCCN=C1C=CC1=CC=CS1
InChI: InChI=1S/C11H14N2S/c1-13-8-3-7-12-11(13)6-5-10-4-2-9-14-10/h2,4-6,9H,3,7-8H2,1H3
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- G Toscan, A S Cezar, R C F Pereira, G B Silva, L A Sangioni, L S S Oliveira, F S F Vogel. Comparative performance of macrocyclic lactones against large strongyles in horses.
Parasitology international.
2012 Dec; 61(4):550-3. doi:
10.1016/j.parint.2012.05.001. [PMID: 22580448] - Anu Näreaho, Jutta Puomio, Kaisa Saarinen, Pikka Jokelainen, Tiina Juselius, Antti Sukura. Feline intestinal parasites in Finland: prevalence, risk factors and anthelmintic treatment practices.
Journal of feline medicine and surgery.
2012 Jun; 14(6):378-83. doi:
10.1177/1098612x12439257. [PMID: 22328587] - Jozef Vercruysse, Jerzy M Behnke, Marco Albonico, Shaali Makame Ame, Cécile Angebault, Jeffrey M Bethony, Dirk Engels, Bertrand Guillard, Thi Viet Hoa Nguyen, Gagandeep Kang, Deepthi Kattula, Andrew C Kotze, James S McCarthy, Zeleke Mekonnen, Antonio Montresor, Maria Victoria Periago, Laurentine Sumo, Louis-Albert Tchuem Tchuenté, Thi Cam Thach Dang, Ahmed Zeynudin, Bruno Levecke. Assessment of the anthelmintic efficacy of albendazole in school children in seven countries where soil-transmitted helminths are endemic.
PLoS neglected tropical diseases.
2011 Mar; 5(3):e948. doi:
10.1371/journal.pntd.0000948. [PMID: 21468309] - K Schmid, N Rohdich, E Zschiesche, D J Kok, M J Allan. Efficacy, safety and palatability of a new broad-spectrum anthelmintic formulation in dogs.
The Veterinary record.
2010 Oct; 167(17):647-51. doi:
10.1136/vr.c4661. [PMID: 21257464] - Anne M Becher, Kurt Pfister. [The efficacy of anthelmintic drugs against horse strongyles in the area of Salzburg and preliminary results of selective anthelmintic treatment].
Wiener klinische Wochenschrift.
2010 Oct; 122 Suppl 3(?):71-5. doi:
10.1007/s00508-010-1441-y. [PMID: 20924696] - A M Becher, M Mahling, M K Nielsen, K Pfister. Selective anthelmintic therapy of horses in the Federal states of Bavaria (Germany) and Salzburg (Austria): an investigation into strongyle egg shedding consistency.
Veterinary parasitology.
2010 Jul; 171(1-2):116-22. doi:
10.1016/j.vetpar.2010.03.001. [PMID: 20356680] - Piyanan Taweethavonsawat, Sudchit Chungpivat, Pakkawan Satranarakun, Rebecca J Traub, Roland Schaper. Efficacy of a combination product containing pyrantel, febantel and praziquantel (Drontal Plus Flavour, Bayer Animal Health) against experimental infection with the hookworm Ancylostoma ceylanicum in dogs.
Parasitology research.
2010 Jan; 106(2):533-7. doi:
10.1007/s00436-009-1665-9. [PMID: 19911198] - Eva Osterman Lind, Dan Christensson. Anthelmintic efficacy on Parascaris equorum in foals on Swedish studs.
Acta veterinaria Scandinavica.
2009 Nov; 51(?):45. doi:
10.1186/1751-0147-51-45. [PMID: 19930608] - Fabrizia Veronesi, Iolanda Moretta, Annabella Moretti, Daniela Piergili Fioretti, Claudio Genchi. Field effectiveness of pyrantel and failure of Parascaris equorum egg count reduction following ivermectin treatment in Italian horse farms.
Veterinary parasitology.
2009 Apr; 161(1-2):138-41. doi:
10.1016/j.vetpar.2009.01.004. [PMID: 19201100] - Andrew C Kotze, Steven R Kopp. The potential impact of density dependent fecundity on the use of the faecal egg count reduction test for detecting drug resistance in human hookworms.
PLoS neglected tropical diseases.
2008 Oct; 2(10):e297. doi:
10.1371/journal.pntd.0000297. [PMID: 18827883] - Jerzy M Behnke, David J Buttle, Gillian Stepek, Ann Lowe, Ian R Duce. Developing novel anthelmintics from plant cysteine proteinases.
Parasites & vectors.
2008 Sep; 1(1):29. doi:
10.1186/1756-3305-1-29. [PMID: 18761736] - Steven R Kopp, Glen T Coleman, James S McCarthy, Andrew C Kotze. Application of in vitro anthelmintic sensitivity assays to canine parasitology: detecting resistance to pyrantel in Ancylostoma caninum.
Veterinary parasitology.
2008 Apr; 152(3-4):284-93. doi:
10.1016/j.vetpar.2007.12.020. [PMID: 18242867] - K Lindgren, O Ljungvall, O Nilsson, B-L Ljungström, C Lindahl, J Höglund. Parascaris equorum in foals and in their environment on a Swedish stud farm, with notes on treatment failure of ivermectin.
Veterinary parasitology.
2008 Feb; 151(2-4):337-43. doi:
10.1016/j.vetpar.2007.10.014. [PMID: 18077096] - Judd L Walson, Grace John-Stewart. Treatment of helminth co-infection in individuals with HIV-1: A systematic review of the literature.
PLoS neglected tropical diseases.
2007 Dec; 1(3):e102. doi:
10.1371/journal.pntd.0000102. [PMID: 18160978] - Donato Traversa, Thomas R Klei, Raffaella Iorio, Barbara Paoletti, Riccardo P Lia, Domenico Otranto, Olivier A E Sparagano, Annunziata Giangaspero. Occurrence of anthelmintic resistant equine cyathostome populations in central and southern Italy.
Preventive veterinary medicine.
2007 Dec; 82(3-4):314-20. doi:
10.1016/j.prevetmed.2007.07.006. [PMID: 17719664] - J B Abbott, D J Mellor, S Love. Assessment of serum protein electrophoresis for monitoring therapy of naturally acquired equine cyathostomin infections.
Veterinary parasitology.
2007 Jun; 147(1-2):110-7. doi:
10.1016/j.vetpar.2007.03.020. [PMID: 17462826] - E Grandemange, E Claerebout, C Genchi, M Franc. Field evaluation of the efficacy and the safety of a combination of oxantel/pyrantel/praziquantel in the treatment of naturally acquired gastrointestinal nematode and/or cestode infestations in dogs in Europe.
Veterinary parasitology.
2007 Apr; 145(1-2):94-9. doi:
10.1016/j.vetpar.2006.11.013. [PMID: 17184919] - Steven R Kopp, Andrew C Kotze, James S McCarthy, Glen T Coleman. High-level pyrantel resistance in the hookworm Ancylostoma caninum.
Veterinary parasitology.
2007 Feb; 143(3-4):299-304. doi:
10.1016/j.vetpar.2006.08.036. [PMID: 17011128] - E T Lyons, S C Tolliver, R A Rathgeber, S S Collins. Parasite field study in central Kentucky on thoroughbred foals (born in 2004) treated with pyrantel tartrate daily and other parasiticides periodically.
Parasitology research.
2007 Feb; 100(3):473-8. doi:
10.1007/s00436-006-0289-6. [PMID: 17013652] - E Osterman Lind, T Kuzmina, A Uggla, P J Waller, J Höglund. A field study on the effect of some anthelmintics on cyathostomins of horses in sweden.
Veterinary research communications.
2007 Jan; 31(1):53-65. doi:
10.1007/s11259-006-3402-5. [PMID: 17186406] - P Hördegen, J Cabaret, H Hertzberg, W Langhans, V Maurer. In vitro screening of six anthelmintic plant products against larval Haemonchus contortus with a modified methyl-thiazolyl-tetrazolium reduction assay.
Journal of ethnopharmacology.
2006 Nov; 108(1):85-9. doi:
10.1016/j.jep.2006.04.013. [PMID: 16725288] - J Owen D Slocombe, Rolph V G de Gannes. Cyathostomes in horses in Canada resistant to pyrantel salts and effectively removed by moxidectin.
Veterinary parasitology.
2006 Aug; 140(1-2):181-4. doi:
10.1016/j.vetpar.2006.03.019. [PMID: 16682123] - Craig R Reinemeyer, Douglas E Hutchens, Wm P Eckblad, Alan A Marchiondo, Jack I Shugart. Dose-confirmation studies of the cestocidal activity of pyrantel pamoate paste in horses.
Veterinary parasitology.
2006 Jun; 138(3-4):234-9. doi:
10.1016/j.vetpar.2006.02.008. [PMID: 16530970] - K C Comer, M H Hillyer, G C Coles. Anthelmintic use and resistance on thoroughbred training yards in the UK.
The Veterinary record.
2006 Apr; 158(17):596-8. doi:
10.1136/vr.158.17.596. [PMID: 16648441] - Alan A Marchiondo, Gary W White, Larry L Smith, Craig R Reinemeyer, John J Dascanio, Edward G Johnson, Jack I Shugart. Clinical field efficacy and safety of pyrantel pamoate paste (19.13\% w/w pyrantel base) against Anoplocephala spp. in naturally infected horses.
Veterinary parasitology.
2006 Apr; 137(1-2):94-102. doi:
10.1016/j.vetpar.2005.12.019. [PMID: 16434142] - Andrea V Scorza, Steven V Radecki, Michael R Lappin. Efficacy of a combination of febantel, pyrantel, and praziquantel for the treatment of kittens experimentally infected with Giardia species.
Journal of feline medicine and surgery.
2006 Feb; 8(1):7-13. doi:
10.1016/j.jfms.2005.04.004. [PMID: 16011902] - Emily L Brazik, Jan T Luquire, Dianne Little. Pyrantel pamoate resistance in horses receiving daily administration of pyrantel tartrate.
Journal of the American Veterinary Medical Association.
2006 Jan; 228(1):101-3. doi:
10.2460/javma.228.1.101. [PMID: 16426178] - Mary G Rossano, Harold C Schott, John B Kaneene, Alice J Murphy, Elizabeth A Kruttlin, Melissa T Hines, Debra C Sellon, Jon S Patterson, Hany M Elsheikha, J P Dubey, Linda S Mansfield. Effect of daily administration of pyrantel tartrate in preventing infection in horses experimentally challenged with Sarcocystis neurona.
American journal of veterinary research.
2005 May; 66(5):846-52. doi:
10.2460/ajvr.2005.66.846. [PMID: 15934612] - Eva Osterman Lind, Arvid Uggla, Peter Waller, Johan Höglund. Larval development assay for detection of anthelmintic resistance in cyathostomins of Swedish horses.
Veterinary parasitology.
2005 Mar; 128(3-4):261-9. doi:
10.1016/j.vetpar.2004.11.029. [PMID: 15740863] - E-M King, H T Kim, N T Dang, E Michael, L Drake, C Needham, R Haque, D A P Bundy, J P Webster. Immuno-epidemiology of Ascaris lumbricoides infection in a high transmission community: antibody responses and their impact on current and future infection intensity.
Parasite immunology.
2005 Mar; 27(3):89-96. doi:
10.1111/j.1365-3024.2005.00753.x. [PMID: 15882235] - John B Githiori, Johan Höglund, Peter J Waller, R Leyden Baker. Evaluation of anthelmintic properties of extracts from some plants used as livestock dewormers by pastoralist and smallholder farmers in Kenya against Heligmosomoides polygyrus infections in mice.
Veterinary parasitology.
2003 Dec; 118(3-4):215-26. doi:
10.1016/j.vetpar.2003.10.006. [PMID: 14729169] - P Hördegen, H Hertzberg, J Heilmann, W Langhans, V Maurer. The anthelmintic efficacy of five plant products against gastrointestinal trichostrongylids in artificially infected lambs.
Veterinary parasitology.
2003 Nov; 117(1-2):51-60. doi:
10.1016/j.vetpar.2003.07.027. [PMID: 14597279] - W Peng, X Zhou, R B Gasser. Ascaris egg profiles in human faeces: biological and epidemiological implications.
Parasitology.
2003 Sep; 127(Pt 3):283-90. doi:
10.1017/s0031182003003615. [PMID: 12964831] - E Frontera, A Carrón, F J Serrano, A Roepstorff, D Reina, I Navarrete. Specific systemic IgG1, IgG2 and IgM responses in pigs immunized with infective eggs or selected antigens of Ascaris suum.
Parasitology.
2003 Sep; 127(Pt 3):291-8. doi:
10.1017/s003118200300355x. [PMID: 12964832] - D Little, J R Flowers, B H Hammerberg, S Y Gardner. Management of drug-resistant cyathostominosis on a breeding farm in central North Carolina.
Equine veterinary journal.
2003 May; 35(3):246-51. doi:
10.2746/042516403776148264. [PMID: 12755426] - Tadaaki Satou, Nobuaki Akao, Rinako Matsuhashi, Kazuo Koike, Koichiro Fujita, Tamotsu Nikaido. Inhibitory effect of isoquinoline alkaloids on movement of second-stage larvae of Toxocara canis.
Biological & pharmaceutical bulletin.
2002 Dec; 25(12):1651-4. doi:
10.1248/bpb.25.1651. [PMID: 12499659] - Ray M Kaplan. Anthelmintic resistance in nematodes of horses.
Veterinary research.
2002 Sep; 33(5):491-507. doi:
10.1051/vetres:2002035. [PMID: 12387486] - Jennifer Keiser, Eliézer K N'Goran, Mahamadou Traoré, Kouassi L Lohourignon, Burton H Singer, Christian Lengeler, Marcel Tanner, Jürg Utzinger. Polyparasitism with Schistosoma mansoni, geohelminths, and intestinal protozoa in rural Côte d'Ivoire.
The Journal of parasitology.
2002 Jun; 88(3):461-6. doi:
10.1645/0022-3395(2002)088[0461:pwsmga]2.0.co;2. [PMID: 12099412] - Patricia A Payne, Robert K Ridley, Michael W Dryden, Christine Bathgate, George A Milliken, Patricia W Stewart. Efficacy of a combination febantel-praziquantel-pyrantel product, with or without vaccination with a commercial Giardia vaccine, for treatment of dogs with naturally occurring giardiasis.
Journal of the American Veterinary Medical Association.
2002 Feb; 220(3):330-3. doi:
10.2460/javma.2002.220.330. [PMID: 11829263] - M M Larsen, S Lendal, M Chriél, S N Olsen, H Bjørn. Risk factors for high endoparasitic burden and the efficiency of a single anthelmintic treatment of Danish horses.
Acta veterinaria Scandinavica.
2002; 43(2):99-106. doi:
10.1186/1751-0147-43-99. [PMID: 12173507] - S Gerwert, K Failing, C Bauer. Prevalence of levamisole and benzimidazole resistance in oesophagostomum populations of pig-breeding farms in North Rhine-Westphalia, Germany.
Parasitology research.
2002 Jan; 88(1):63-8. doi:
10.1007/s004360100507. [PMID: 11822739] - A Ishih, M Yanoh, C Ikeya, A Ban, M Terada. Effects of anthelmintics on the development of eggs of Angiostrongylus costaricensis in vitro.
Journal of helminthology.
2001 Dec; 75(4):351-4. doi:
10.1017/s0022149x01000531. [PMID: 11818052]
