4,4'-Thiobis(6-tert-butyl-m-cresol) (BioDeep_00000175467)
human metabolite blood metabolite Industrial Pollutants
代谢物信息卡片
化学式: C22H30O2S (358.1966)
中文名称: 4,4-硫代双(6-叔丁基间甲酚), 4,4'-硫代双(6-叔丁基间甲酚)
谱图信息:
最多检出来源 Homo sapiens(blood) 100%
分子结构信息
SMILES: CC1=CC(=C(C=C1SC2=CC(=C(C=C2C)O)C(C)(C)C)C(C)(C)C)O
InChI: InChI=1S/C22H30O2S/c1-13-9-17(23)15(21(3,4)5)11-19(13)25-20-12-16(22(6,7)8)18(24)10-14(20)2/h9-12,23-24H,1-8H3
数据库引用编号
6 个数据库交叉引用编号
- PubChem: 7308
- HMDB: HMDB0247683
- ChEMBL: CHEMBL1526319
- chemspider: 7034
- CAS: 57062-46-1
- CAS: 96-69-5
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Hiroshi Matsumoto, Fumiyo Saito, Masahiro Takeyoshi. Investigation of the early-response genes in chemical-induced renal carcinogenicity for the prediction of chemical carcinogenicity in rats.
The Journal of toxicological sciences.
2017; 42(2):175-181. doi:
10.2131/jts.42.175. [PMID: 28321044] - L P Myers, B F Law, A Fedorowicz, P D Siegel, L F Butterworth, S E Anderson, G Sussman, M Shapiro, B J Meade, D Beezhold. Identification of phenolic dermal sensitizers in a wound closure tape.
Journal of immunotoxicology.
2007 Oct; 4(4):303-10. doi:
10.1080/15476910701680236. [PMID: 18958741] - R S Zand, D J Jenkins, E P Diamandis. Steroid hormone activity of flavonoids and related compounds.
Breast cancer research and treatment.
2000 Jul; 62(1):35-49. doi:
10.1023/a:1006422302173. [PMID: 10989984] - A E Munson, K L White, D W Barnes, D L Musgrove, H H Lysy, M P Holsapple. An immunotoxicological evaluation of 4,4'-thiobis-(6-t-butyl-m-cresol) in female B6C3F1 mice. 1. Body and organ weights, hematology, serum chemistries, bone marrow cellularity, and hepatic microsomal parameters.
Fundamental and applied toxicology : official journal of the Society of Toxicology.
1988 May; 10(4):691-700. doi:
10.1016/0272-0590(88)90196-0. [PMID: 3396795] - M P Holsapple, K L White, J A McCay, S G Bradley, A E Munson. An immunotoxicological evaluation of 4,4'-thiobis-(6-t-butyl-m-cresol) in female B6C3F1 mice. 2. Humoral and cell-mediated immunity, macrophage function, and host resistance.
Fundamental and applied toxicology : official journal of the Society of Toxicology.
1988 May; 10(4):701-16. doi:
10.1016/0272-0590(88)90197-2. [PMID: 3396796] - S J Borghoff, S A Stefanski, L S Birnbaum. The effect of age on the glucuronidation and toxicity of 4,4'-thiobis(6-t-butyl-m-cresol).
Toxicology and applied pharmacology.
1988 Mar; 92(3):453-66. doi:
10.1016/0041-008x(88)90185-8. [PMID: 3127943] - L S Birnbaum, S M Heaney. Dermal absorption of the antioxidant 4,4'-thiobis(6-tert-butyl-m-cresol) in Sencar mice and Fischer rats.
Toxicology letters.
1987 Jun; 37(1):13-9. doi:
10.1016/0378-4274(87)90161-5. [PMID: 3590225] - L S Birnbaum, W C Eastin, L Johnson, H B Matthews. Disposition of 4,4'-thiobis(6-t-butyl-m-cresol) in rats.
Drug metabolism and disposition: the biological fate of chemicals.
1983 Nov; 11(6):537-43. doi:
NULL. [PMID: 6140136] - S Tsuji, K Nakagawa, T Fukushima. Genetically controlled quantitative variation of ornithine transcarbamylase in the chick kidney.
Biochemical genetics.
1983 Oct; 21(9-10):857-69. doi:
10.1007/bf00483945. [PMID: 6419722] - H H Borden, R W Harris, W E Mosher. A waterborne outbreak of gastroenteritis in western New York State.
American journal of public health and the nation's health.
1970 Feb; 60(2):283-8. doi:
10.2105/ajph.60.2.283. [PMID: 5460971]
