Dotmp (BioDeep_00000175441)

   

human metabolite blood metabolite


代谢物信息卡片


{[4,7,10-tris(phosphonomethyl)-1,4,7,10-tetraazacyclododecan-1-yl]methyl}phosphonic acid

化学式: C12H32N4O12P4 (548.0967152)
中文名称: 1,4,7,10-四氮杂环十二烷-1,4,7,10-四(甲基膦酸)
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1CN(CCN(CCN(CCN1CP(=O)(O)O)CP(=O)(O)O)CP(=O)(O)O)CP(=O)(O)O
InChI: InChI=1S/C12H32N4O12P4/c17-29(18,19)9-13-1-2-14(10-30(20,21)22)5-6-16(12-32(26,27)28)8-7-15(4-3-13)11-31(23,24)25/h1-12H2,(H2,17,18,19)(H2,20,21,22)(H2,23,24,25)(H2,26,27,28)

描述信息

同义名列表

7 个代谢物同义名

{[4,7,10-tris(phosphonomethyl)-1,4,7,10-tetraazacyclododecan-1-yl]methyl}phosphonic acid; 1,4,7,10-Tetraazacyclododecanetrayl-1,4,7,10-tetrakis(methylene)tetrakisphosphonic acid; [4,7,10-tris(phosphonomethyl)-1,4,7,10-tetraazacyclododecan-1-yl]methylphosphonic acid; 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrayl-tetrakis(methylphosphonic acid); 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetrakis(methylenephosphonic acid); 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetra(methylene phosphonic acid); Dotmp



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Hazel B Breitz, Richard E Wendt, Michael S Stabin, Sui Shen, William D Erwin, Joseph G Rajendran, Janet F Eary, Lawrence Durack, Ebrahim Delpassand, William Martin, Ruby F Meredith. 166Ho-DOTMP radiation-absorbed dose estimation for skeletal targeted radiotherapy. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2006 Mar; 47(3):534-42. doi: NULL. [PMID: 16513624]
  • Gjermund Henriksen, Oyvind S Bruland, Roy H Larsen. Thorium and actinium polyphosphonate compounds as bone-seeking alpha particle-emitting agents. Anticancer research. 2004 Jan; 24(1):101-5. doi: NULL. [PMID: 15015582]
  • Sergio Giralt, William Bensinger, Mark Goodman, Donald Podoloff, Janet Eary, Richard Wendt, Raymond Alexanian, Donna Weber, David Maloney, Leona Holmberg, Joseph Rajandran, Hazel Breitz, Richard Ghalie, Richard Champlin. 166Ho-DOTMP plus melphalan followed by peripheral blood stem cell transplantation in patients with multiple myeloma: results of two phase 1/2 trials. Blood. 2003 Oct; 102(7):2684-91. doi: 10.1182/blood-2002-10-3250. [PMID: 12730103]
  • Hazel Breitz, Richard Wendt, Michael Stabin, Lionel Bouchet, Barry Wessels. Dosimetry of high dose skeletal targeted radiotherapy (STR) with 166Ho-DOTMP. Cancer biotherapy & radiopharmaceuticals. 2003 Apr; 18(2):225-30. doi: 10.1089/108497803765036391. [PMID: 12804048]
  • P Caravan, M T Greenfield, X Li, A D Sherry. The Gd(3+) complex of a fatty acid analogue of DOTP binds to multiple albumin sites with variable water relaxivities. Inorganic chemistry. 2001 Dec; 40(26):6580-7. doi: 10.1021/ic0102900. [PMID: 11735466]
  • S Hassfjell, K Ingebrigtsen, Ø S Bruland . Synthesis, purification and biodistribution of (205)Bi-DOTMP, visualizing bone deposition patterns with autoradiography. Nuclear medicine and biology. 2001 May; 28(4):425-33. doi: 10.1016/s0969-8051(01)00202-5. [PMID: 11395316]