Toxaphene (BioDeep_00000175280)

   

human metabolite blood metabolite


代谢物信息卡片


1,4,5,6,7,7-hexachloro-2,2-bis(chloromethyl)-3-methylidenebicyclo[2.2.1]heptane

化学式: C10H8Cl8 (407.8134208)
中文名称: 毒杀芬
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C=C1C(C2(C(C(C1(C2(Cl)Cl)Cl)Cl)Cl)Cl)(CCl)CCl
InChI: InChI=1S/C10H8Cl8/c1-4-7(2-11,3-12)9(16)6(14)5(13)8(4,15)10(9,17)18/h5-6H,1-3H2

描述信息

D010575 - Pesticides > D007306 - Insecticides
D016573 - Agrochemicals

同义名列表

3 个代谢物同义名

1,4,5,6,7,7-hexachloro-2,2-bis(chloromethyl)-3-methylidenebicyclo[2.2.1]heptane; Polychlorocamphene; toxaphene



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yukiko Fujii, Kouji H Harada, Yoshiko Ito, Miho Yoshitake, Chiharu Matsunobu, Yoshihisa Kato, Chiho Ohta, Nobuyuki Koga, Osamu Kimura, Tetsuya Endo, Akio Koizumi, Koichi Haraguchi. Profiles and determinants of dicofol, endosulfans, mirex, and toxaphenes in breast milk samples from 10 prefectures in Japan. Chemosphere. 2023 Jan; 311(Pt 1):137002. doi: 10.1016/j.chemosphere.2022.137002. [PMID: 36419270]
  • Christopher J Martyniuk, Alvine C Mehinto, Reyna Cristina Colli-Dula, Kevin J Kroll, Nicholas J Doperalski, David S Barber, Nancy D Denslow. Transcriptome and physiological effects of toxaphene on the liver-gonad reproductive axis in male and female largemouth bass (Micropterus salmoides). Comparative biochemistry and physiology. Part D, Genomics & proteomics. 2020 12; 36(?):100746. doi: 10.1016/j.cbd.2020.100746. [PMID: 32992212]
  • Lea Reger, Christoph Gallistl, Karl Skírnisson, Walter Vetter. Analysis and Characterization of Polychlorinated Hydroxybornanes as Metabolites of Toxaphene Using a Polar Bear Model. Environmental science & technology. 2017 Aug; 51(15):8335-8342. doi: 10.1021/acs.est.7b02662. [PMID: 28686017]
  • Zemin Wang, Barbara H Neal, James C Lamb, James E Klaunig. Mechanistic Investigation of Toxaphene Induced Mouse Liver Tumors. Toxicological sciences : an official journal of the Society of Toxicology. 2015 Oct; 147(2):549-61. doi: 10.1093/toxsci/kfv151. [PMID: 26187448]
  • Katrin Vorkamp, Frank F Rigét, Rune Dietz. Toxaphene in the aquatic environment of Greenland. Environmental pollution (Barking, Essex : 1987). 2015 May; 200(?):140-8. doi: 10.1016/j.envpol.2015.02.014. [PMID: 25728301]
  • Katrin Vorkamp, Søren Møller, Knud Falk, Frank F Rigét, Marianne Thomsen, Peter B Sørensen. Levels and trends of toxaphene and chlordane-related pesticides in peregrine falcon eggs from South Greenland. The Science of the total environment. 2014 Jan; 468-469(?):614-21. doi: 10.1016/j.scitotenv.2013.08.073. [PMID: 24056452]
  • Terry F Bidleman, Gary A Stern, Gregg T Tomy, Barry T Hargrave, Liisa M Jantunen, Robie W Macdonald. Scavenging amphipods: sentinels for penetration of mercury and persistent organic chemicals into food webs of the deep Arctic Ocean. Environmental science & technology. 2013 Jun; 47(11):5553-61. doi: 10.1021/es304398j. [PMID: 23627492]
  • Shaoqiong Tian, Xiuhong Mao, Shui Miao, Zhengwei Jia, Ke Wang, Shen Ji. [Determination of seven toxaphene congeners in ginseng and milkvetch root by gas chromatography tandem mass spectrometry]. Se pu = Chinese journal of chromatography. 2012 Jan; 30(1):14-20. doi: 10.3724/sp.j.1123.2011.09019. [PMID: 22667085]
  • R A Vigen, D Chen, U Syversen, K Stunes, R Hakanson, C-M Zhao. Serum gastrin and gastric enterochromaffin-like cells during estrous cycle, pregnancy and lactation, and in response to estrogen-like agents in rats. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 2011 Jun; 62(3):335-40. doi: . [PMID: 21893694]
  • Seonock Woo, Seungshic Yum. Transcriptional response of marine medaka (Oryzias javanicus) on exposure to toxaphene. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2011 Apr; 153(3):355-61. doi: 10.1016/j.cbpc.2010.12.006. [PMID: 21220043]
  • Michel Aubé, Christian Larochelle, Pierre Ayotte. Differential effects of a complex organochlorine mixture on the proliferation of breast cancer cell lines. Environmental research. 2011 Apr; 111(3):337-47. doi: 10.1016/j.envres.2011.01.010. [PMID: 21295777]
  • Kjetil Sagerup, Vladimir Savinov, Tatiana Savinova, Vadim Kuklin, Derek C G Muir, Geir W Gabrielsen. Persistent organic pollutants, heavy metals and parasites in the glaucous gull (Larus hyperboreus) on Spitsbergen. Environmental pollution (Barking, Essex : 1987). 2009 Aug; 157(8-9):2282-90. doi: 10.1016/j.envpol.2009.03.031. [PMID: 19364623]
  • Heli Routti, Bert van Bavel, Robert J Letcher, Augustine Arukwe, Shaogang Chu, Geir W Gabrielsen. Concentrations, patterns and metabolites of organochlorine pesticides in relation to xenobiotic phase I and II enzyme activities in ringed seals (Phoca hispida) from Svalbard and the Baltic Sea. Environmental pollution (Barking, Essex : 1987). 2009 Aug; 157(8-9):2428-34. doi: 10.1016/j.envpol.2009.03.008. [PMID: 19329238]
  • Erin L Pulster, Kelly L Smalling, Eric Zolman, Lori Schwacke, Keith A Maruya. Persistent organochlorine pollutants and toxaphene congener profiles in bottlenose dolphins (Tursiops truncatus) frequenting the Turtle/Brunswick River Estuary (TBRE) in coastal Georgia, USA. Environmental toxicology and chemistry. 2009 Jul; 28(7):1390-9. doi: 10.1897/08-240.1. [PMID: 19203137]
  • Jaakko Paasivirta, Seija Sinkkonen, Vladimir Nikiforov, Fedor Kryuchkov, Erkki Kolehmainen, Katri Laihia, Arto Valkonen, Manu Lahtinen. Long-range atmospheric transport of three toxaphene congeners across Europe. Modeling by chained single-box FATEMOD program. Environmental science and pollution research international. 2009 Mar; 16(2):191-205. doi: 10.1007/s11356-008-0084-2. [PMID: 19132429]
  • A Polder, C Thomsen, G Lindström, K B Løken, J U Skaare. Levels and temporal trends of chlorinated pesticides, polychlorinated biphenyls and brominated flame retardants in individual human breast milk samples from Northern and Southern Norway. Chemosphere. 2008 Aug; 73(1):14-23. doi: 10.1016/j.chemosphere.2008.06.002. [PMID: 18653208]
  • B Gouteux, D C G Muir, S Backus, E W Born, R Dietz, T Haug, T Metcalfe, C Metcalfe, N Øien. Toxaphene in minke whales (Balaenoptera acutorostrata) from the North Atlantic. Environmental pollution (Barking, Essex : 1987). 2008 May; 153(1):71-83. doi: 10.1016/j.envpol.2007.07.031. [PMID: 17913318]
  • M P Gunderson, S Kohno, B Blumberg, T Iguchi, L J Guillette. Up-regulation of the alligator CYP3A77 gene by toxaphene and dexamethasone and its short term effect on plasma testosterone concentrations. Aquatic toxicology (Amsterdam, Netherlands). 2006 Jun; 78(3):272-83. doi: 10.1016/j.aquatox.2005.11.010. [PMID: 16713641]
  • Mitsuha Yoshikane, Winston R Kay, Yasuyuki Shibata, Maki Inoue, Tokuma Yanai, Ryo Kamata, John S Edmonds, Masatoshi Morita. Very high concentrations of DDE and toxaphene residues in crocodiles from the Ord River, Western Australia: an investigation into possible endocrine disruption. Journal of environmental monitoring : JEM. 2006 Jun; 8(6):649-61. doi: 10.1039/b518059g. [PMID: 16767233]
  • Erin L Pulster, Kelly L Smalling, Keith A Maruya. Polychlorinated biphenyls and toxaphene in preferred prey fish of coastal southeastern U.S. bottlenose dolphins (Tursiops truncatus). Environmental toxicology and chemistry. 2005 Dec; 24(12):3128-36. doi: 10.1897/05-156r.1. [PMID: 16445095]
  • M Coreen Hamilton, Ronald A Hites, Steven J Schwager, Jeffery A Foran, Barbara A Knuth, David O Carpenter. Lipid composition and contaminants in farmed and wild salmon. Environmental science & technology. 2005 Nov; 39(22):8622-9. doi: 10.1021/es050898y. [PMID: 16323755]
  • Sobhy Hamed, Guenter Leupold, Ahmed Ismail, Harun Parlar. Enantioselective determination of chiral toxaphene congeners in laying hens and eggs using multidimensional high-resolution gas chromatography. Journal of agricultural and food chemistry. 2005 Sep; 53(18):7156-64. doi: 10.1021/jf050801r. [PMID: 16131124]
  • C A Blanar, M A Curtis, H M Chan. Growth, nutritional composition, and hematology of Arctic charr (Salvelinus alpinus) exposed to toxaphene and tapeworm (Diphyllobothrium dendriticum) larvae. Archives of environmental contamination and toxicology. 2005 Apr; 48(3):397-404. doi: 10.1007/s00244-004-0064-6. [PMID: 15719195]
  • Bruno Gouteux, Michel Lebeuf, Mike O Hammill, Derek C G Muir, Jean-Pierre Gagné. Comparison of toxaphene congeners levels in five seal species from eastern Canada: what is the importance of biological factors?. Environmental science & technology. 2005 Mar; 39(6):1448-54. doi: 10.1021/es048886k. [PMID: 15819196]
  • Brendan McHugh, Evin McGovern, Eugene Nixon, Jarle Klungsøyr, Gerhard G Rimkus, Pim E Leonards, Jacob deBoer. Baseline survey of concentrations of toxaphene congeners in fish from European waters. Journal of environmental monitoring : JEM. 2004 Aug; 6(8):665-72. doi: 10.1039/b403169e. [PMID: 15292948]
  • Matthew R Milnes, Davina Allen, Teresa A Bryan, Cassidy D Sedacca, Louis J Guillette. Developmental effects of embryonic exposure to toxaphene in the American alligator (Alligator mississippiensis). Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2004 May; 138(1):81-7. doi: 10.1016/j.cca.2004.05.006. [PMID: 15313450]
  • John R Barr, Adrian R Woolfitt, Vincent L Maggio, Donald G Patterson. Measurement of toxaphene congeners in pooled human serum collected in three U.S. cities using high-resolution mass spectrometry. Archives of environmental contamination and toxicology. 2004 May; 46(4):551-6. doi: 10.1007/s00244-003-3128-0. [PMID: 15253054]
  • Jeffrey G McDonald, Ronald A Hites. Radial dilution model for the distribution of toxaphene in the United States and Canada on the basis of measured concentrations in tree bark. Environmental science & technology. 2003 Feb; 37(3):475-81. doi: 10.1021/es020707g. [PMID: 12630461]
  • Valérie Lavastre, Charles J Roberge, Martin Pelletier, Marc Gauthier, Denis Girard. Toxaphene, but not beryllium, induces human neutrophil chemotaxis and apoptosis via reactive oxygen species (ROS): involvement of caspases and ROS in the degradation of cytoskeletal proteins. Clinical immunology (Orlando, Fla.). 2002 Jul; 104(1):40-8. doi: 10.1006/clim.2002.5226. [PMID: 12139946]
  • K D Scott, G E Fåhraeus-Van Ree, C C Parrish. Sex differences in hepatic lipids of Toxaphene-exposed juvenile yellowtail flounder (Pleuronectes ferrugineus Storer). Ecotoxicology and environmental safety. 2002 Mar; 51(3):168-76. doi: 10.1006/eesa.2001.2135. [PMID: 11971637]
  • S Chen, D Zhou, C Yang, T Okubo, Y Kinoshita, B Yu, Y C Kao, T Itoh. Modulation of aromatase expression in human breast tissue. The Journal of steroid biochemistry and molecular biology. 2001 Dec; 79(1-5):35-40. doi: 10.1016/s0960-0760(01)00132-7. [PMID: 11850205]
  • F Bryce, F Iverson, P Andrews, M Barker, W Cherry, R Mueller, O Pulido, S Hayward, S Fernie, D L Arnold. Effects elicited by toxaphene in the cynomolgus monkey (Macaca fascicularis): a pilot study. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2001 Dec; 39(12):1243-51. doi: 10.1016/s0278-6915(01)00068-0. [PMID: 11696398]
  • H Tryphonas, D L Arnold, F Bryce, J Huang, M Hodgen, D T Ladouceur, S Fernie, M Lepage-Parenteau, S Hayward. Effects of toxaphene on the immune system of cynomolgus (Macaca fascicularis) monkeys. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2001 Sep; 39(9):947-58. doi: 10.1016/s0278-6915(01)00035-7. [PMID: 11498272]
  • D L Arnold, F Bryce, C Baccanale, S Hayward, J R Tanner, E MacLellan, T Dearden, S Fernie. Toxicological consequences of toxaphene ingestion by cynomolgus (Macaca fascicularis) monkeys. Part 1: pre-mating phase. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2001 May; 39(5):467-76. doi: 10.1016/s0278-6915(00)00151-4. [PMID: 11313113]
  • W Vetter, U Klobes, B Luckas. Distribution and levels of eight toxaphene congeners in different tissues of marine mammals, birds and cod livers. Chemosphere. 2001 May; 43(4-7):611-21. doi: 10.1016/s0045-6535(00)00413-6. [PMID: 11372845]
  • A E Bayoumi, Y Pérez-Pertejo, C Ordóñez, R M Reguera, R Balaña-Fouce, D Ordóñez. Changes in the glutathione-redox balance induced by the pesticides heptachlor, chlordane, and toxaphene in CHO-K1 cells. Bulletin of environmental contamination and toxicology. 2000 Dec; 65(6):748-55. doi: 10.1007/s0012800186. [PMID: 11080355]
  • Y H Wen, H M Chan. A pharmacokinetic model for predicting absorption, elimination, and tissue burden of toxaphene in rats. Toxicology and applied pharmacology. 2000 Nov; 168(3):235-43. doi: 10.1006/taap.2000.9052. [PMID: 11042096]
  • H R Buser, P Haglund, M D Müller, T Poiger, C Rappe. Rapid anaerobic degradation of toxaphene in sewage sludge. Chemosphere. 2000 May; 40(9-11):1213-20. doi: 10.1016/s0045-6535(99)00371-9. [PMID: 10739064]
  • H J de Geus, H Besselink, A Brouwer, J Klungsøyr, B McHugh, E Nixon, G G Rimkus, P G Wester, J de Boer. Environmental occurrence, analysis, and toxicology of toxaphene compounds. Environmental health perspectives. 1999 Feb; 107 Suppl 1(?):115-44. doi: 10.1289/ehp.99107s1115. [PMID: 10229713]
  • S E Rought, P M Yau, L F Chuang, R H Doi, R Y Chuang. Effect of the chlorinated hydrocarbons heptachlor, chlordane, and toxaphene on retinoblastoma tumor suppressor in human lymphocytes. Toxicology letters. 1999 Jan; 104(1-2):127-35. doi: 10.1016/s0378-4274(98)00356-7. [PMID: 10048758]
  • D L Swackhamer, R F Pearson, S P Schottler. Toxaphene in the Great Lakes. Chemosphere. 1998 Oct; 37(9-12):2545-61. doi: 10.1016/s0045-6535(98)00307-5. [PMID: 9828352]
  • J Wolkers, I C Burkow, C Lydersen, S Dahle, M Monshouwer, R F Witkamp. Congener specific PCB and polychlorinated camphene (toxaphene) levels in Svalbard ringed seals (Phoca hispida) in relation to sex, age, condition and cytochrome P450 enzyme activity. The Science of the total environment. 1998 May; 216(1-2):1-11. doi: 10.1016/s0048-9697(98)00131-4. [PMID: 9618926]
  • H J Drenth, C A Bouwman, W Seinen, M Van den Berg. Effects of some persistent halogenated environmental contaminants on aromatase (CYP19) activity in the human choriocarcinoma cell line JEG-3. Toxicology and applied pharmacology. 1998 Jan; 148(1):50-5. doi: 10.1006/taap.1997.8307. [PMID: 9465263]
  • R S Waritz, M Steinberg, F K Kinoshita, C M Kelly, W R Richter. Thyroid function and thyroid tumors in toxaphene-treated rats. Regulatory toxicology and pharmacology : RTP. 1996 Oct; 24(2 Pt 1):184-92. doi: 10.1006/rtph.1996.0124. [PMID: 8933632]
  • U S Gill, H M Schwartz, B Wheatley, H Parlar. Congener specific analysis of toxaphene in serum using ECNI-MS. Chemosphere. 1996 Sep; 33(6):1021-5. doi: 10.1016/0045-6535(96)00243-3. [PMID: 8784997]
  • P Andrews, K Headrick, J C Pilon, F Bryce, F Iverson. Capillary GC-ECD and ECNI GCMS characterization of toxaphene residues in primate tissues during a feeding study. Chemosphere. 1996 Mar; 32(6):1043-53. doi: 10.1016/0045-6535(96)00024-0. [PMID: 8920590]
  • A M Soto, K L Chung, C Sonnenschein. The pesticides endosulfan, toxaphene, and dieldrin have estrogenic effects on human estrogen-sensitive cells. Environmental health perspectives. 1994 Apr; 102(4):380-3. doi: 10.1289/ehp.94102380. [PMID: 7925178]
  • J Chandra, G Durairaj. Effect of toxaphene toxicity on enzyme activity & residue levels in vital organs of guineapig. The Indian journal of medical research. 1993 Aug; 98(?):193-8. doi: NULL. [PMID: 8262581]
  • A K Chaturvedi, D J Kuntz, N G Rao. Metabolic aspects of the toxicology of mixtures of parathion, toxaphene and/or 2,4-D in mice. Journal of applied toxicology : JAT. 1991 Aug; 11(4):245-51. doi: 10.1002/jat.2550110404. [PMID: 1658105]
  • D J Kuntz, N G Rao, I E Berg, R Khattree, A K Chaturvedi. Toxicity of mixtures of parathion, toxaphene and/or 2,4-D in mice. Journal of applied toxicology : JAT. 1990 Aug; 10(4):257-66. doi: 10.1002/jat.2550100406. [PMID: 2391407]
  • A Mohammed, A Eklund, A M Ostlund-Lindqvist, P Slanina. Tissue accumulation of lipoprotein associated toxaphene in normo- and hypolipidemic mice. Archives of toxicology. 1990; 64(1):38-42. doi: 10.1007/bf01973374. [PMID: 2306192]
  • A Mohammed, A Eklund, A M Ostlund-Lindqvist, P Slanina. Distribution of toxaphene, DDT, and PCB among lipoprotein fractions in rat and human plasma. Archives of toxicology. 1990; 64(7):567-71. doi: 10.1007/bf01971836. [PMID: 2127352]
  • I Chu, V Secours, D C Villeneuve, V E Valli, A Nakamura, D Colin, D J Clegg, E P Arnold. Reproduction study of toxaphene in the rat. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. 1988 Apr; 23(2):101-26. doi: 10.1080/03601238809372591. [PMID: 3385132]
  • I Chu, D C Villeneuve, C W Sun, V Secours, B Procter, E Arnold, D Clegg, L Reynolds, V E Valli. Toxicity of toxaphene in the rat and beagle dog. Fundamental and applied toxicology : official journal of the Society of Toxicology. 1986 Oct; 7(3):406-18. doi: 10.1016/0272-0590(86)90090-4. [PMID: 3781130]
  • C H Trottman, K S Prasada Rao, W Morrow, J E Uzodinma, D Desaiah. In vitro effects of toxaphene on mitochondrial calcium ATPase and calcium uptake in selected rat tissues. Life sciences. 1985 Feb; 36(5):427-33. doi: 10.1016/0024-3205(85)90254-1. [PMID: 3155819]
  • M Mourelle, M Garcia, C Aguilar. Adenosine triphosphatase activities in plasma liver membranes of rats treated with DDT and toxaphene. Journal of applied toxicology : JAT. 1985 Feb; 5(1):39-41. doi: 10.1002/jat.2550050108. [PMID: 2985682]
  • M García, M Mourelle. Gamma-glutamyl transpeptidase: a sensitive marker in DDT and toxaphene exposure. Journal of applied toxicology : JAT. 1984 Oct; 4(5):246-8. doi: 10.1002/jat.2550040506. [PMID: 6150953]
  • A Mohammed, O Andersson, A Biessmann, P Slanina. Fate and specific tissue retention of toxaphene in mice. Archives of toxicology. 1983 Dec; 54(4):311-21. doi: 10.1007/bf01234484. [PMID: 6667122]
  • A Biessmann, A Mohammed, P Slanina. Studies on the tissue disposition and fate of [14C]toxaphene in Japanese quail. Toxicology. 1983 Sep; 28(1-2):155-65. doi: 10.1016/0300-483x(83)90114-2. [PMID: 6636198]
  • G A Pollock, R Hillstrand. The elimination, distribution, and metabolism of 14C-toxaphene in the pregnant rat. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. 1982; 17(6):635-48. doi: 10.1080/03601238209372347. [PMID: 7166626]
  • J M Poul, J Pays, M Dagorn. [Polychlorocamphane (P.C.C.) effects on the microsomal enzyme activities and fat content of rat liver (author's transl)]. Toxicological European research. Recherche europeenne en toxicologie. 1981 May; 3(3):153-9. doi: NULL. [PMID: 7281166]
  • L A Steele, H A Nelson, A A Furr, D L Osheim, P F Ross, S A Lund. Toxaphene residues in the bovine after oral exposure. Veterinary and human toxicology. 1980 Oct; 22(5):312-4. doi: NULL. [PMID: 7456301]
  • M E Mount, V Traffas, R J Milleret, F W Oehme. An unusual occurrence of toxaphene poisoning in swine. Journal of the American Veterinary Medical Association. 1980 Sep; 177(5):445-7. doi: NULL. [PMID: 7440343]
  • G A Pollock, W Kilgore. Excretion and storage of [14C]toxaphene and two isolated [14C]toxaphene fractions. Journal of toxicology and environmental health. 1980 Jan; 6(1):127-40. doi: 10.1080/15287398009529836. [PMID: 7381966]
  • C H Trottman, D Desaiah. Induction of rat hepatic microsomal enzymes by toxaphene pretreatment. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. 1980; 15(1):121-34. doi: 10.1080/03601238009372168. [PMID: 6766963]
  • M D Reuber. Carcinogenicity of toxaphene: a review. Journal of toxicology and environmental health. 1979 Jul; 5(4):729-48. doi: 10.1080/15287397909529783. [PMID: 385896]
  • M A Saleh, R J Skinner, J E Casida. Comparative metabolism of 2,2,5-endo,6-exo,8,9,10-heptachlorobornane and toxaphene in six mammalian species and chickens. Journal of agricultural and food chemistry. 1979 Jul; 27(4):731-7. doi: 10.1021/jf60224a072. [PMID: 117038]
  • D B Peakall. Effect of toxaphene on pyruvic and lactic acid levels in the rat. Environmental health perspectives. 1979 Jun; 30(?):97-8. doi: 10.1289/ehp.793097. [PMID: 446465]
  • U A Kuz'minskaya, V A Ivanitskiĭ. Study of some biological indices of the state of the sympathoadrenaline system under the effect of polychlorocamphene. Environmental health perspectives. 1979 Jun; 30(?):91-5. doi: 10.1289/ehp.793091. [PMID: 446464]
  • C H Trottman, D Desaiah. Adenosine triphosphatase activities in brain, kidney and liver of mice treated with toxaphene. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. 1979; 14(4):393-404. doi: 10.1080/03601237909372137. [PMID: 224087]
  • P S Chandurkar, F Matsumura. Metabolism of toxaphene components in rats. Archives of environmental contamination and toxicology. 1979; 8(1):1-24. doi: 10.1007/bf01055137. [PMID: 533306]
  • J N Seiber, W L Winterlin, M M McChesney. Residues of toxaphene, DEF, and paraquat in plant parts and gin waste from a treated cotton field. Archives of environmental contamination and toxicology. 1979; 8(2):125-37. doi: 10.1007/bf01056319. [PMID: 539830]
  • G P Bogachuk, V E Filenko. [Effect of general vertical vibration and polychlorocamphene on the kidneys of inbred rats]. Arkhiv anatomii, gistologii i embriologii. 1978 Jul; 75(7):24-7. doi: NULL. [PMID: 687123]
  • U A Kuz'minskaia, V A Ivanitskiĭ. [Functional state of the sympathetic-adrenal system under the effect of organochlorine insecticides]. Vrachebnoe delo. 1978 Jun; ?(6):127-30. doi: NULL. [PMID: 80882]
  • U A Kuz'minskaya, S M Alekhina. Effect of chlorocamphene on the isoenzyme spectrum of lactate dehydrogenase in rat serum and liver. Environmental health perspectives. 1976 Feb; 13(?):127-32. doi: 10.1289/ehp.7613127. [PMID: 1269500]
  • D B Peakall. Effects of toxaphene on hepatic enzyme induction and circulating steroid levels in the rat. Environmental health perspectives. 1976 Feb; 13(?):117-20. doi: 10.1289/ehp.7613117. [PMID: 1269498]
  • H Gertig, W Nowaczyk. The influence of carathane and toxaphene on the activity of some enzymes in rat's tissues in the studies in vivo. Polish journal of pharmacology and pharmacy. 1975 Jul; 27(4):357-64. doi: . [PMID: 1166018]
  • C K Maitai, J A Kamau, D M Gacuhi, S Njoroge. An outbreak of arsenic and toxaphene poisoning in Kenyan cattle. The Veterinary record. 1975 Feb; 96(7):151-2. doi: 10.1136/vr.96.7.151. [PMID: 1119075]
  • D Desaiah, R B Koch. Toxaphene inhibition of ATPase activity in catfish, ictalurus punctatus, tissues. Bulletin of environmental contamination and toxicology. 1975 Feb; 13(2):238-44. doi: 10.1007/bf01721745. [PMID: 123803]
  • T Ohsawa, J R Knox, S Khalifa, J E Casida. Metabolic dechlorination of toxaphene in rats. Journal of agricultural and food chemistry. 1975 Jan; 23(1):98-106. doi: 10.1021/jf60197a021. [PMID: 1133285]
  • J E Casida, R L Holmstead, S Khalifa, J R Knox, T Ohsawa. Toxaphene composition and metabolism in rats. Environmental quality and safety. Supplement. 1975; 3(?):346-9. doi: NULL. [PMID: 773640]
  • L A Crowder, E F Dindal. Fate of 36C1-toxaphene in rats. Bulletin of environmental contamination and toxicology. 1974 Sep; 12(3):320-7. doi: 10.1007/bf01709126. [PMID: 4433877]
  • J E Casida, R L Holmstead, S Khalifa, J R Knox, T Osawa, K J Palmer, R Y Wong. Toxaphene insecticide: a complex biodegradable mixture. Science (New York, N.Y.). 1974 Feb; 183(4124):520-1. doi: 10.1126/science.183.4124.520. [PMID: 4588619]
  • T L Embry, D P Morgan, C C Roan. Search for abnormalities of heme synthesis and sympathoadrenal activity--in workers regularly exposed to pesticides. Journal of occupational medicine. : official publication of the Industrial Medical Association. 1972 Dec; 14(12):918-21. doi: NULL. [PMID: 4639955]
  • T J HALEY. The insecticides; their hazard in industry and in the home. California medicine. 1956 Apr; 84(4):258-64. doi: . [PMID: 13304690]