8-Azido-cyclic AMP (BioDeep_00000175239)
human metabolite blood metabolite
代谢物信息卡片
6-(6-amino-8-azidopurin-9-yl)-2,7-dihydroxy-tetrahydro-4H-2lambda5-furo[3,2-d][1,3,2]dioxaphosphinin-2-one
化学式: C10H11N8O6P (370.05391560000004)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 50%
分子结构信息
SMILES: C1C2C(C(C(O2)N3C4=NC=NC(=C4N=C3N=[N+]=[N-])N)O)OP(=O)(O1)O
InChI: InChI=1S/C10H11N8O6P/c11-7-4-8(14-2-13-7)18(10(15-4)16-17-12)9-5(19)6-3(23-9)1-22-25(20,21)24-6/h2-3,5-6,9,19H,1H2,(H,20,21)(H2,11,13,14)
描述信息
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D000345 - Affinity Labels
同义名列表
数据库引用编号
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相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
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1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- A Kondrashin, M Nesterova, Y S Cho-Chung. Cyclic adenosine 3':5'-monophosphate-dependent protein kinase on the external surface of LS-174T human colon carcinoma cells.
Biochemistry.
1999 Jan; 38(1):172-9. doi:
10.1021/bi982090e. [PMID: 9890895] - A K Singh, K Taskén, W Walker, R A Frizzell, S C Watkins, R J Bridges, N A Bradbury. Characterization of PKA isoforms and kinase-dependent activation of chloride secretion in T84 cells.
The American journal of physiology.
1998 08; 275(2):C562-70. doi:
10.1152/ajpcell.1998.275.2.c562. [PMID: 9688611] - B E Cohen, G Lee, N Arispe, H B Pollard. Cyclic 3'-5'-adenosine monophosphate binds to annexin I and regulates calcium-dependent membrane aggregation and ion channel activity.
FEBS letters.
1995 Dec; 377(3):444-50. doi:
10.1016/0014-5793(95)01395-4. [PMID: 8549773] - G Müller, W Bandlow. Lipolytic membrane release of two phosphatidylinositol-anchored cAMP receptor proteins in yeast alters their ligand-binding parameters.
Archives of biochemistry and biophysics.
1994 Feb; 308(2):504-14. doi:
10.1006/abbi.1994.1071. [PMID: 8109981] - S M Gapstur, S Homma, T P Dousa. cAMP-binding proteins in medullary tubules from rat kidney: effect of ADH.
The American journal of physiology.
1988 Aug; 255(2 Pt 2):F292-300. doi:
10.1152/ajprenal.1988.255.2.f292. [PMID: 2841870] - A Plet, P Gerbaud, W B Anderson, D Evain-Brion. Effect of phorbol ester on cyclic adenosine 3':5'-monophosphate-dependent protein kinases in PYS teratocarcinoma-derived cells and counteraction with retinoic acid.
Cancer research.
1988 Jul; 48(14):3993-7. doi:
NULL. [PMID: 2838167] - A Y Liu, V Kamalakannan, Z Lin. Induction of the RI cAMP-binding protein in the 'neurite-minus' N1A-103 mouse neuroblastoma cell line.
Biochemical and biophysical research communications.
1987 Oct; 148(1):350-6. doi:
10.1016/0006-291x(87)91117-x. [PMID: 2823808] - L P Kleine, J F Whitfield. Serum-activated T51B rat liver cells transiently accumulate cyclic AMP-dependent protein kinases on their surfaces during the G1 phase.
Journal of cellular physiology.
1987 Aug; 132(2):354-8. doi:
10.1002/jcp.1041320223. [PMID: 3040781] - P Klein, R Vaughan, J Borleis, P Devreotes. The surface cyclic AMP receptor in Dictyostelium. Levels of ligand-induced phosphorylation, solubilization, identification of primary transcript, and developmental regulation of expression.
The Journal of biological chemistry.
1987 Jan; 262(1):358-64. doi:
NULL. [PMID: 3025212] - E P Widmaier, S Osawa, P F Hall. Phosphorylation of three proteins in the plasma membrane of Y-1 adrenal cells by a membrane-bound adenosine 3',5'-monophosphate-dependent protein kinase.
Endocrinology.
1986 Feb; 118(2):701-8. doi:
10.1210/endo-118-2-701. [PMID: 3002763] - K R Johnson, S S Panter, R G Johnson. Phosphorylation of lens membranes with a cyclic AMP-dependent protein kinase purified from the bovine lens.
Biochimica et biophysica acta.
1985 Mar; 844(3):367-76. doi:
10.1016/0167-4889(85)90139-9. [PMID: 2982431] - M Sato, A Hiragun, H Mitsui. Differentiation-associated increase of cAMP-dependent type II protein kinase in a murine preadipose cell line (ST 13).
Biochimica et biophysica acta.
1985 Mar; 844(3):296-305. doi:
10.1016/0167-4889(85)90130-2. [PMID: 2982429] - S C Wen, C M Chang, R W Reitherman, B W Harding. Characterization of cell surface adenosine 3',5'-monophosphate-binding proteins in Y-1 mouse adrenal tumor cells.
Endocrinology.
1985 Mar; 116(3):935-44. doi:
10.1210/endo-116-3-935. [PMID: 2982578] - P B Hoyer, G D Niswender. The regulation of steroidogenesis is different in the two types of ovine luteal cells.
Canadian journal of physiology and pharmacology.
1985 Mar; 63(3):240-8. doi:
10.1139/y85-045. [PMID: 2985223] - A Plet, P Gerbaud, W B Anderson, D E Brion. Changes in the activity and subcellular distribution of cyclic-AMP-dependent protein kinases with retinoic-acid-induced differentiation of embryonal carcinoma cells.
Differentiation; research in biological diversity.
1985; 30(2):159-64. doi:
10.1111/j.1432-0436.1985.tb00527.x. [PMID: 3007248] - B M Boman, M A Zschunke, R E Scott. Topography of protein kinases and phosphoproteins in the plasma membrane of 3T3 cells.
Journal of cellular physiology.
1984 Nov; 121(2):357-67. doi:
10.1002/jcp.1041210213. [PMID: 6092392] - J Erlichman, Y Litvin, N Fleischer. Immunological and molecular characterization of the cAMP-dependent protein kinases in AtT20 cells.
The Journal of biological chemistry.
1984 Aug; 259(16):10289-95. doi:
NULL. [PMID: 6088492] - P Strocchi, V S Sapirstein, C S Rubin, J M Gilbert. Characterization and biosynthesis of cyclic-AMP-binding proteins in the rat central nervous system.
Journal of neurochemistry.
1984 Aug; 43(2):466-71. doi:
10.1111/j.1471-4159.1984.tb00922.x. [PMID: 6330300] - M L Dufau, C A Winters, M Hattori, D Aquilano, J L Barañao, K Nozu, A Baukal, K J Catt. Hormonal regulation of androgen production by the Leydig cell.
Journal of steroid biochemistry.
1984 Jan; 20(1):161-73. doi:
10.1016/0022-4731(84)90203-6. [PMID: 6323862] - P K Schoff, I T Forrester, B E Haley, R W Atherton. A study of cAMP binding proteins on intact and disrupted sperm cells using 8-azidoadenosine 3',5'-cyclic monophosphate.
Journal of cellular biochemistry.
1982; 19(1):1-15. doi:
10.1002/jcb.240190102. [PMID: 6288746] - S T Lord, F M Richards. The labeling with 8-azido-cyclic adenosine monophosphate of proteins in vesicles of sarcoplasmic reticulum from rabbit skeletal muscle.
Biochimica et biophysica acta.
1981 Nov; 649(1):13-23. doi:
10.1016/0005-2736(81)90003-1. [PMID: 6272856] - J M Wehner, A M Malkinson, M F Wiser, J R Sheppard. Cyclic AMP-dependent protein kinases from Balb 3T3 cells and other 3T3 derived lines.
Journal of cellular physiology.
1981 Aug; 108(2):175-84. doi:
10.1002/jcp.1041080208. [PMID: 6267082] - M H Juliani, C Klein. Photoaffinity labeling of the cell surface adenosine 3':5'-monophosphate receptor of Dictyostelium discoideum and its modification in down-regulated cells.
The Journal of biological chemistry.
1981 Jan; 256(2):613-9. doi:
NULL. [PMID: 6256362] - A Y Liu, W W Fiske, K Y Chen. Regulation of cyclic adenosine 3':5'-monophosphate-binding protein in N-18 mouse neuroblastoma cells.
Cancer research.
1980 Nov; 40(11):4100-8. doi:
NULL. [PMID: 6258772] - P K Jaynes, J P McDonough, H R Mahler. Identification of cAMP binding proteins associated with the plasma membrane of the yeast Saccharomyces cerevisiae.
Biochemical and biophysical research communications.
1980 May; 94(1):16-22. doi:
10.1016/s0006-291x(80)80180-x. [PMID: 6248053]