N-(2-Methylpropyl)dodeca-2,4,8,10-tetraenamide (BioDeep_00000175205)

   

human metabolite blood metabolite


代谢物信息卡片


(2E,4E,8Z,10E)-N-(2-Methylpropyl)dodeca-2,4,8,10-tetraenamide

化学式: C16H25NO (247.193604)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC=CC=CCCC=CC=CC(=O)NCC(C)C
InChI: InChI=1S/C16H25NO/c1-4-5-6-7-8-9-10-11-12-13-16(18)17-14-15(2)3/h4-7,10-13,15H,8-9,14H2,1-3H3,(H,17,18)

描述信息

同义名列表

7 个代谢物同义名

(2E,4E,8Z,10E)-N-(2-Methylpropyl)dodeca-2,4,8,10-tetraenamide; N-(2-Methylpropyl)dodeca-2,4,8,10-tetraenimidate; N-(2-METHYLPROPYL)DODECA-2,4,8,10-TETRAENAMIDE; Dodeca-2,4,8,10-tetraenoic acid isobutylamide; 2,4,8,10-Dodecatetraenoic acid isobutylamide; N-Isobutyl-2,4,8,10-dodecatetraenamide; C12En4CONHiB



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

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Plant Reactome(0)

INOH(0)

PlantCyc(0)

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1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Andrew K L Goey, Hilde Rosing, Irma Meijerman, Rolf W Sparidans, Jan H M Schellens, Jos H Beijnen. The bioanalysis of the major Echinacea purpurea constituents dodeca-2E,4E,8Z,10E/Z-tetraenoic acid isobutylamides in human plasma using LC-MS/MS. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2012 Aug; 902(?):151-6. doi: 10.1016/j.jchromb.2012.06.022. [PMID: 22770780]
  • Karin Ardjomand-Woelkart, Manfred Kollroser, Christoph Magnes, Frank Sinner, Reginald F Frye, Hartmut Derendorf, Rudolf Bauer, Veronika Butterweck. Absolute/relative bioavailability and metabolism of dodeca-2E,4E,8Z,10E/Z-tetraenoic acid isobutylamides (tetraenes) after intravenous and oral single doses to rats. Planta medica. 2011 Nov; 77(16):1794-9. doi: 10.1055/s-0030-1271120. [PMID: 21604240]
  • Karin Woelkart, Reginald F Frye, Hartmut Derendorf, Rudolf Bauer, Veronika Butterweck. Pharmacokinetics and tissue distribution of dodeca-2E,4E,8E,10E/Z-tetraenoic acid isobutylamides after oral administration in rats. Planta medica. 2009 Oct; 75(12):1306-13. doi: 10.1055/s-0029-1185631. [PMID: 19399718]
  • Ah-Reum Han, Hye Jeoung Kim, Minkyu Shin, Moochang Hong, Yang Seok Kim, Hyunsu Bae. Constituents of Asarum sieboldii with inhibitory activity on lipopolysaccharide (LPS)-induced NO production in BV-2 microglial cells. Chemistry & biodiversity. 2008 Feb; 5(2):346-51. doi: 10.1002/cbdv.200890033. [PMID: 18293448]
  • Stefan Raduner, William Bisson, Ruben Abagyan, Karl-Heinz Altmann, Jürg Gertsch. Self-assembling cannabinomimetics: supramolecular structures of N-alkyl amides. Journal of natural products. 2007 Jun; 70(6):1010-5. doi: 10.1021/np060598+. [PMID: 17497806]
  • A Matthias, E M J Gillam, K G Penman, N J Matovic, K M Bone, J J De Voss, R P Lehmann. Cytochrome P450 enzyme-mediated degradation of Echinacea alkylamides in human liver microsomes. Chemico-biological interactions. 2005 Jun; 155(1-2):62-70. doi: 10.1016/j.cbi.2005.04.003. [PMID: 15885678]
  • Karin Woelkart, Christoph Koidl, Andrea Grisold, J David Gangemi, Ronald B Turner, Egon Marth, Rudolf Bauer. Bioavailability and pharmacokinetics of alkamides from the roots of Echinacea angustifolia in humans. Journal of clinical pharmacology. 2005 Jun; 45(6):683-9. doi: 10.1177/0091270004273493. [PMID: 15901750]
  • Feng Zhang, Chang-Hu Chu, Qing Xu, Shao-Ping Fu, Jie-Han Hu, Hong-Bin Xiao, Xin-Miao Liang. A new amide from Asarum forbesii Maxim. Journal of Asian natural products research. 2005 Feb; 7(1):1-5. doi: 10.1080/10286020310001596015. [PMID: 15621594]
  • Magali Laasonen, Tero Wennberg, Tuulikki Harmia-Pulkkinen, Heikki Vuorela. Simultaneous analysis of alkamides and caffeic acid derivatives for the identification of Echinacea purpurea, Echinacea angustifolia, Echinacea pallida and Parthenium integrifolium roots. Planta medica. 2002 Jun; 68(6):572-4. doi: 10.1055/s-2002-32561. [PMID: 12094312]
  • Ji-ren Li, Yu-ying Zhao, Tie-min Ai. [Advances in the study of the chemical constituents and biological activities of 3 species of Echinacea]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2002 May; 27(5):334-7. doi: ". [PMID: 12814096]
  • B Dietz, J Heilmann, R Bauer. Absorption of dodeca-2E,4E,8Z,10E/Z-tetraenoic acid isobutylamides after oral application of Echinacea purpurea tincture. Planta medica. 2001 Dec; 67(9):863-4. doi: 10.1055/s-2001-18846. [PMID: 11745026]
  • J Livesey, D V Awang, J T Arnason, W Letchamo, M Barrett, G Pennyroyal. Effect of temperature on stability of marker constituents in Echinacea purpurea root formulations. Phytomedicine : international journal of phytotherapy and phytopharmacology. 1999 Nov; 6(5):347-9. doi: 10.1016/s0944-7113(99)80057-9. [PMID: 11962542]