8-Anilino-5-(4-anilino-5-sulfonaphthalen-1-yl)naphthalene-1-sulfonic acid (BioDeep_00000175014)

   

human metabolite blood metabolite


代谢物信息卡片


8-Anilino-5-(4-anilino-5-sulphonaphthalen-1-yl)naphthalene-1-sulphonic acid

化学式: C32H24N2O6S2 (596.1075724)
中文名称: 双(苯)铬(0)
谱图信息: 最多检出来源 Homo sapiens(blood) 91.67%

分子结构信息

SMILES: C1=CC=C(C=C1)NC2=C3C(=C(C=C2)C4=C5C=CC=C(C5=C(C=C4)NC6=CC=CC=C6)S(=O)(=O)O)C=CC=C3S(=O)(=O)O
InChI: InChI=1S/C32H24N2O6S2/c35-41(36,37)29-15-7-13-25-23(17-19-27(31(25)29)33-21-9-3-1-4-10-21)24-18-20-28(34-22-11-5-2-6-12-22)32-26(24)14-8-16-30(32)42(38,39)40/h1-20,33-34H,(H,35,36,37)(H,38,39,40)

描述信息

D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D049408 - Luminescent Agents
D004396 - Coloring Agents > D005456 - Fluorescent Dyes

同义名列表

15 个代谢物同义名

8-Anilino-5-(4-anilino-5-sulphonaphthalen-1-yl)naphthalene-1-sulphonic acid; 8-Anilino-5-(4-anilino-5-sulfonaphthalen-1-yl)naphthalene-1-sulfonic acid; 8-Anilino-5-(4-anilino-5-sulphonaphthalen-1-yl)naphthalene-1-sulphonate; 8-Anilino-5-(4-anilino-5-sulfonaphthalen-1-yl)naphthalene-1-sulfonate; 4,4-bis(phenylamino)-[1,1-binaphthalene]-5,5-disulfonic acid; 4,4-Dianilino-1,1-binaphthalene-5,5-disulfonic acid; 4,4-Dianilino-1,1-bisnaphthyl-5,5 disulfonic acid; 5,5-Bis(8-(phenylamino)-1-naphthalenesulfonate); 1,1-Bis(4-anilino-5-naphthalenesulfonic acid); 4,4-Bis(8-phenylamino)naphthalene-1-sulfonate; 4,4-Bis(1-anilino-8-naphthalenesulfonate); Bis(1,8-anilinonaphthalenesulfonate); 5,5-Bis(ans); 4,4-BANS; Bis-ans



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Huiying Bai, Zhen Cao, Sha Meng, Rui Ge, Shurong Ban, Yuanlin Zhang, Li Tang, Qing-Shan Li. Synthesis and Anti-Inflammatory Activity Evaluation of Benzoxazole Derivatives as New Myeloid Differentiation Protein 2 Inhibitors. Chemistry & biodiversity. 2023 Jun; 20(6):e202201145. doi: 10.1002/cbdv.202201145. [PMID: 37080925]
  • Mu Yang, Colina Dutta, Ashutosh Tiwari. Disulfide-bond scrambling promotes amorphous aggregates in lysozyme and bovine serum albumin. The journal of physical chemistry. B. 2015 Mar; 119(10):3969-81. doi: 10.1021/acs.jpcb.5b00144. [PMID: 25689578]
  • Anne Bertling, Silke Niemann, Muzaffar Hussain, Lisa Holbrook, Ronald G Stanley, Martin F Brodde, Silke Pohl, Tina Schifferdecker, Joachim Roth, Kerstin Jurk, Anja Müller, Judith Lahav, Georg Peters, Christine Heilmann, Jonathan M Gibbins, Beate E Kehrel. Staphylococcal extracellular adherence protein induces platelet activation by stimulation of thiol isomerases. Arteriosclerosis, thrombosis, and vascular biology. 2012 Aug; 32(8):1979-90. doi: 10.1161/atvbaha.112.246249. [PMID: 22539594]
  • Rajeshwer S Sankhala, Rajani S Damai, Musti J Swamy. Correlation of membrane binding and hydrophobicity to the chaperone-like activity of PDC-109, the major protein of bovine seminal plasma. PloS one. 2011 Mar; 6(3):e17330. doi: 10.1371/journal.pone.0017330. [PMID: 21408153]
  • Andrea Hawe, Robert Poole, Wim Jiskoot. Misconceptions over Förster resonance energy transfer between proteins and ANS/bis-ANS: Direct excitation dominates dye fluorescence. Analytical biochemistry. 2010 Jun; 401(1):99-106. doi: 10.1016/j.ab.2010.02.031. [PMID: 20197057]
  • Eman Basha, Christopher Jones, Vicki Wysocki, Elizabeth Vierling. Mechanistic differences between two conserved classes of small heat shock proteins found in the plant cytosol. The Journal of biological chemistry. 2010 Apr; 285(15):11489-97. doi: 10.1074/jbc.m109.074088. [PMID: 20145254]
  • Christian Krintel, Matthias Mörgelin, Derek T Logan, Cecilia Holm. Phosphorylation of hormone-sensitive lipase by protein kinase A in vitro promotes an increase in its hydrophobic surface area. The FEBS journal. 2009 Sep; 276(17):4752-62. doi: 10.1111/j.1742-4658.2009.07172.x. [PMID: 19664063]
  • Xinmiao Fu, Zengyi Chang. Identification of bis-ANS binding sites in Mycobacterium tuberculosis small heat shock protein Hsp16.3: evidences for a two-step substrate-binding mechanism. Biochemical and biophysical research communications. 2006 Oct; 349(1):167-71. doi: 10.1016/j.bbrc.2006.08.036. [PMID: 16930542]
  • Monica Freitas, Andrea T Da Poian, Ortrud M Barth, Moacyr A Rebello, Jerson L Silva, Luciane P Gaspar. The fusogenic state of Mayaro virus induced by low pH and by hydrostatic pressure. Cell biochemistry and biophysics. 2006; 44(3):325-35. doi: 10.1385/cbb:44:3:325. [PMID: 16679519]
  • Ji Hee Yu, Keun Pill Kim, Soo Min Park, Choo Bong Hong. Biochemical analysis of a cytosolic small heat shock protein, NtHSP18.3, from Nicotiana tabacum. Molecules and cells. 2005 Jun; 19(3):328-33. doi: ". [PMID: 15995348]
  • Albena T Dinkova-Kostova, W David Holtzclaw, Nobunao Wakabayashi. Keap1, the sensor for electrophiles and oxidants that regulates the phase 2 response, is a zinc metalloprotein. Biochemistry. 2005 May; 44(18):6889-99. doi: 10.1021/bi047434h. [PMID: 15865434]
  • Xinmiao Fu, Xuefeng Zhang, Zengyi Chang. 4,4'-Dianilino-1,1'-binaphthyl-5,5'-sulfonate, a novel molecule having chaperone-like activity. Biochemical and biophysical research communications. 2005 Apr; 329(3):1087-93. doi: 10.1016/j.bbrc.2005.01.164. [PMID: 15752765]
  • Aivar Lookene, Liyan Zhang, Magnus Hultin, Gunilla Olivecrona. Rapid subunit exchange in dimeric lipoprotein lipase and properties of the inactive monomer. The Journal of biological chemistry. 2004 Nov; 279(48):49964-72. doi: 10.1074/jbc.m407419200. [PMID: 15385564]
  • Manoj Majee, Susmita Maitra, Krishnarup Ghosh Dastidar, Sitakanta Pattnaik, Anirban Chatterjee, Nitai C Hait, Kali Pada Das, Arun Lahiri Majumder. A novel salt-tolerant L-myo-inositol-1-phosphate synthase from Porteresia coarctata (Roxb.) Tateoka, a halophytic wild rice: molecular cloning, bacterial overexpression, characterization, and functional introgression into tobacco-conferring salt tolerance phenotype. The Journal of biological chemistry. 2004 Jul; 279(27):28539-52. doi: 10.1074/jbc.m310138200. [PMID: 15016817]
  • Alexander V Pastukhov, Ira J Ropson. Fluorescent dyes as probes to study lipid-binding proteins. Proteins. 2003 Nov; 53(3):607-15. doi: 10.1002/prot.10401. [PMID: 14579352]
  • Qiang Xie, Tai Guo, Tingting Wang, Jie Lu, Hai-Meng Zhou. Aspartate-induced aminoacylase folding and forming of molten globule. The international journal of biochemistry & cell biology. 2003 Nov; 35(11):1558-72. doi: 10.1016/s1357-2725(03)00131-6. [PMID: 12824065]
  • Aivar Lookene, Liyan Zhang, Vello Tougu, Gunilla Olivecrona. 1,1'-bis(anilino)-4-,4'-bis(naphtalene)-8,8'-disulfonate acts as an inhibitor of lipoprotein lipase and competes for binding with apolipoprotein CII. The Journal of biological chemistry. 2003 Sep; 278(39):37183-94. doi: 10.1074/jbc.m303894200. [PMID: 12855707]
  • Dong Ryoung Kim, Ick Lee, Sung Chul Ha, Kyeong Kyu Kim. Activation mechanism of HSP16.5 from Methanococcus jannaschii. Biochemical and biophysical research communications. 2003 Aug; 307(4):991-8. doi: 10.1016/s0006-291x(03)01302-0. [PMID: 12878210]
  • María Soledad Celej, Guillermo G Montich, Gerardo D Fidelio. Protein stability induced by ligand binding correlates with changes in protein flexibility. Protein science : a publication of the Protein Society. 2003 Jul; 12(7):1496-506. doi: 10.1110/ps.0240003. [PMID: 12824495]
  • H Zoellner, J Y Hou, T Hochgrebe, A Poljak, M W Duncan, J Golding, T Henderson, G Lynch. Fluorometric and mass spectrometric analysis of nonenzymatic glycosylated albumin. Biochemical and biophysical research communications. 2001 Jun; 284(1):83-9. doi: 10.1006/bbrc.2001.4924. [PMID: 11374874]
  • L P Gaspar, A F Terezan, A S Pinheiro, D Foguel, M A Rebello, J L Silva. The metastable state of nucleocapsids of enveloped viruses as probed by high hydrostatic pressure. The Journal of biological chemistry. 2001 Mar; 276(10):7415-21. doi: 10.1074/jbc.m010037200. [PMID: 11092899]
  • R Dorfman, P N Walsh. Noncovalent interactions of the Apple 4 domain that mediate coagulation factor XI homodimerization. The Journal of biological chemistry. 2001 Mar; 276(9):6429-38. doi: 10.1074/jbc.m010340200. [PMID: 11092900]
  • C C Silva, V Giongo, A J Simpson, E R Camargos, J L Silva, M C Koury. Effects of hydrostatic pressure on the Leptospira interrogans: high immunogenicity of the pressure-inactivated serovar hardjo. Vaccine. 2001 Jan; 19(11-12):1511-4. doi: 10.1016/s0264-410x(00)00361-3. [PMID: 11163675]
  • F A Carneiro, A S Ferradosa, A T Da Poian. Low pH-induced conformational changes in vesicular stomatitis virus glycoprotein involve dramatic structure reorganization. The Journal of biological chemistry. 2001 Jan; 276(1):62-7. doi: 10.1074/jbc.m008753200. [PMID: 11024041]
  • C F Bonafe, M Glaser, E W Voss, G Weber, J L Silva. Virus inactivation by anilinonaphthalene sulfonate compounds and comparison with other ligands. Biochemical and biophysical research communications. 2000 Sep; 275(3):955-61. doi: 10.1006/bbrc.2000.3402. [PMID: 10973827]
  • D L LeDuc, Y K Shin, R F Epand, R M Epand. Factors determining vesicular lipid mixing induced by shortened constructs of influenza hemagglutinin. Biochemistry. 2000 Mar; 39(10):2733-9. doi: 10.1021/bi992457v. [PMID: 10704225]
  • I B Nagy, M A Alsina, I Haro, F Reig, F Hudecz. Phospholipid-model membrane interactions with branched polypeptide conjugates of a hepatitis A virus peptide epitope. Bioconjugate chemistry. 2000 Jan; 11(1):30-8. doi: 10.1021/bc9900385. [PMID: 10639082]
  • A Angelakou, G Valsami, P Macheras, M Koupparis. A displacement approach for competitive drug-protein binding studies using the potentiometric 1-anilino-8-naphthalene-sulfonate probe technique. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 1999 Dec; 9(2):123-30. doi: 10.1016/s0928-0987(99)00036-6. [PMID: 10620724]
  • M E Georgiou, C A Georgiou, M A Koupparis. Automated flow injection gradient technique for binding studies of micromolecules to proteins using potentiometric sensors: application to bovine serum albumin with anilinonaphthalenesulfonate probe and drugs. Analytical chemistry. 1999 Jul; 71(13):2541-50. doi: 10.1021/ac981019b. [PMID: 10405613]
  • I Benito, M L Marina, J M Saz, J C Diez-Masa. Detection of bovine whey proteins by on-column derivatization capillary electrophoresis with laser-induced fluorescence monitoring. Journal of chromatography. A. 1999 May; 841(1):105-14. doi: 10.1016/s0021-9673(99)00272-1. [PMID: 10360330]
  • H Winter, J L Huber, S C Huber. Membrane association of sucrose synthase: changes during the graviresponse and possible control by protein phosphorylation. FEBS letters. 1997 Dec; 420(2-3):151-5. doi: 10.1016/s0014-5793(97)01506-8. [PMID: 9459300]
  • A A Raibekas, V Massey. Glycerol-assisted restorative adjustment of flavoenzyme conformation perturbed by site-directed mutagenesis. The Journal of biological chemistry. 1997 Aug; 272(35):22248-52. doi: 10.1074/jbc.272.35.22248. [PMID: 9268372]
  • G J Lee, A M Roseman, H R Saibil, E Vierling. A small heat shock protein stably binds heat-denatured model substrates and can maintain a substrate in a folding-competent state. The EMBO journal. 1997 Feb; 16(3):659-71. doi: 10.1093/emboj/16.3.659. [PMID: 9034347]
  • L F Arbelaez, P E Jensen, V P Shanbhag, T Stigbrand. Probing different conformational states of pregnancy-zone protein. Fluorescence studies utilizing the binding of 4,4'-bis(8-anilino-1-naphthalenesulphonate). European journal of biochemistry. 1993 Dec; 218(2):651-6. doi: 10.1111/j.1432-1033.1993.tb18419.x. [PMID: 8269956]
  • R Jarabak, J Westley. Competitive partial inhibitors of serum albumin-catalyzed sulfur cyanolysis. Journal of biochemical toxicology. 1990; 5(1):1-8. doi: 10.1002/jbt.2570050102. [PMID: 2402002]
  • L E Morrison, G Weber. Biological membrane modeling with a liquid/liquid interface. Probing mobility and environment with total internal reflection excited fluorescence. Biophysical journal. 1987 Sep; 52(3):367-79. doi: 10.1016/s0006-3495(87)83225-3. [PMID: 3651556]
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