4-(2-Aminoethyl)-5-fluoro-1,2-benzenediol (BioDeep_00000174927)
human metabolite blood metabolite
代谢物信息卡片
化学式: C8H10FNO2 (171.06955320000003)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 50%
分子结构信息
SMILES: C1=C(C(=CC(=C1O)O)F)CCN
InChI: InChI=1S/C8H10FNO2/c9-6-4-8(12)7(11)3-5(6)1-2-10/h3-4,11-12H,1-2,10H2
描述信息
同义名列表
数据库引用编号
5 个数据库交叉引用编号
- PubChem: 122237
- HMDB: HMDB0247061
- ChEMBL: CHEMBL41818
- chemspider: 109012
- CAS: 71144-39-3
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Olli Eskola, Tove J Grönroos, Alexandru Naum, Päivi Marjamäki, Sarita Forsback, Jörgen Bergman, Sami Länkimäki, Jan Kiss, Timo Savunen, Juhani Knuuti, Merja Haaparanta, Olof Solin. Novel electrophilic synthesis of 6-[¹⁸F]fluorodopamine and comprehensive biological evaluation.
European journal of nuclear medicine and molecular imaging.
2012 May; 39(5):800-10. doi:
10.1007/s00259-011-2032-5
. [PMID: 22231017] - Lucia Martiniova, Susannah Cleary, Edwin W Lai, Dale O Kiesewetter, Jurgen Seidel, Linda F Dawson, Jacqueline K Phillips, David Thomasson, Xiaoyuan Chen, Graeme Eisenhofer, James F Powers, Richard Kvetnansky, Karel Pacak. Usefulness of [18F]-DA and [18F]-DOPA for PET imaging in a mouse model of pheochromocytoma.
Nuclear medicine and biology.
2012 Feb; 39(2):215-26. doi:
10.1016/j.nucmedbio.2011.07.007
. [PMID: 21958851] - Mio Kitano, Corina Millo, Reza Rahbari, Peter Herscovitch, Krisana Gesuwan, Richard C Webb, Aradhana M Venkatesan, Giao Q Phan, Marybeth S Hughes, Steven K Libutti, Naris Nilubol, William M Linehan, Electron Kebebew. Comparison of 6-18F-fluoro-L-DOPA, 18F-2-deoxy-D-glucose, CT, and MRI in patients with pancreatic neuroendocrine neoplasms with von Hippel-Lindau disease.
Surgery.
2011 Dec; 150(6):1122-8. doi:
10.1016/j.surg.2011.09.048
. [PMID: 22136831] - Henri J L M Timmers, Graeme Eisenhofer, Jorge A Carrasquillo, Clara C Chen, Millie Whatley, Alexander Ling, Karen T Adams, Karel Pacak. Use of 6-[18F]-fluorodopamine positron emission tomography (PET) as first-line investigation for the diagnosis and localization of non-metastatic and metastatic phaeochromocytoma (PHEO).
Clinical endocrinology.
2009 Jul; 71(1):11-7. doi:
10.1111/j.1365-2265.2008.03496.x
. [PMID: 19138315] - I Ilias, K Pacak. Diagnosis, localization and treatment of pheochromocytoma in MEN 2 syndrome.
Endocrine regulations.
2009 Apr; 43(2):89-93. doi:
. [PMID: 19856714]
- Richard Imrich, Basil A Eldadah, Oladi Bentho, Sandra Pechnik, Yehonatan Sharabi, Courtney Holmes, Ehud Grossman, David S Goldstein. Functional effects of cardiac sympathetic denervation in neurogenic orthostatic hypotension.
Parkinsonism & related disorders.
2009 Feb; 15(2):122-7. doi:
10.1016/j.parkreldis.2008.04.002
. [PMID: 18514012] - Joël J Aerts, Alain R Plenevaux, Christian F Lemaire, Fabrice Giacomelli, Geoffrey I Warnock, Christophe L Phillips, André J Luxen. Metabolism of no-carrier-added 2-[18F]fluoro-L-tyrosine in rats.
BMC medical physics.
2008 Nov; 8(?):4. doi:
10.1186/1756-6649-8-4
. [PMID: 18990255] - David S Goldstein, Graeme Eisenhofer, John A Flynn, Gary Wand, Karel Pacak. Diagnosis and localization of pheochromocytoma.
Hypertension (Dallas, Tex. : 1979).
2004 May; 43(5):907-10. doi:
10.1161/01.hyp.0000125014.56023.b8
. [PMID: 15023935] - Loukas Gourgiotis, Nicholas J Sarlis, James C Reynolds, Carter VanWaes, Maria J Merino, Karel Pacak. Localization of medullary thyroid carcinoma metastasis in a multiple endocrine neoplasia type 2A patient by 6-[18F]-fluorodopamine positron emission tomography.
The Journal of clinical endocrinology and metabolism.
2003 Feb; 88(2):637-41. doi:
10.1210/jc.2002-021354
. [PMID: 12574193] - K Pacak, D S Goldstein, J L Doppman, B L Shulkin, R Udelsman, G Eisenhofer. A 'pheo' lurks: novel approaches for locating occult pheochromocytoma.
The Journal of clinical endocrinology and metabolism.
2001 Aug; 86(8):3641-6. doi:
10.1210/jcem.86.8.7714
. [PMID: 11502790] - G Seitz, H B Stegmann, H H Jäger, H M Schlude, H Wolburg, V A Roginsky, D Niethammer, G Bruchelt. Neuroblastoma cells expressing the noradrenaline transporter are destroyed more selectively by 6-fluorodopamine than by 6-hydroxydopamine.
Journal of neurochemistry.
2000 Aug; 75(2):511-20. doi:
10.1046/j.1471-4159.2000.0750511.x
. [PMID: 10899926] - S F Lu, B Herbert, G Haufe, K W Laue, W L Padgett, O Oshunleti, J W Daly, K L Kirk. Syntheses of (R)- and (S)-2- and 6-fluoronorepinephrine and (R)- and (S)-2- and 6-fluoroepinephrine: effect of stereochemistry on fluorine-induced adrenergic selectivities.
Journal of medicinal chemistry.
2000 Apr; 43(8):1611-9. doi:
10.1021/jm990599h
. [PMID: 10780918]