5-Fluoro-adb, (+/-)- (BioDeep_00000174891)
human metabolite blood metabolite
代谢物信息卡片
化学式: C20H28FN3O3 (377.2115)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 83.33%
分子结构信息
SMILES: CC(C)(C)C(C(=O)OC)NC(=O)C1=NN(C2=CC=CC=C21)CCCCCF
InChI: InChI=1S/C20H28FN3O3/c1-20(2,3)17(19(26)27-4)22-18(25)16-14-10-6-7-11-15(14)24(23-16)13-9-5-8-12-21/h6-7,10-11,17H,5,8-9,12-13H2,1-4H3,(H,22,25)
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Christian V Cabanlong, Lauren N Russell, William E Fantegrossi, Paul L Prather. Metabolites of Synthetic Cannabinoid 5F-MDMB-PINACA Retain Affinity, Act as High Efficacy Agonists and Exhibit Atypical Pharmacodynamic Properties at CB1 Receptors.
Toxicological sciences : an official journal of the Society of Toxicology.
2022 04; 187(1):175-185. doi:
10.1093/toxsci/kfac024. [PMID: 35201352] - Franziska Gaunitz, Hilke Andresen-Streichert. Analytical findings in a non-fatal intoxication with the synthetic cannabinoid 5F-ADB (5F-MDMB-PINACA): a case report.
International journal of legal medicine.
2022 Mar; 136(2):577-589. doi:
10.1007/s00414-021-02717-6. [PMID: 34921326] - Sophie Salle, Christelle Sevestre, Camille Richeval, Florian Hakim, Delphine Allorge, Jean-Michel Gaulier. Involuntary 5F-ADB-related intoxication following e-cigarette use.
International journal of legal medicine.
2021 Jul; 135(4):1467-1470. doi:
10.1007/s00414-021-02561-8. [PMID: 33765158] - Brandon C Presley, Marisol S Castaneto, Barry K Logan, Susan A Jansen-Varnum. Metabolic profiling of synthetic cannabinoid 5F-ADB and identification of metabolites in authentic human blood samples via human liver microsome incubation and ultra-high-performance liquid chromatography/high-resolution mass spectrometry.
Rapid communications in mass spectrometry : RCM.
2020 Nov; 34(22):e8908. doi:
10.1002/rcm.8908. [PMID: 32710798] - Jessica A Hvozdovich, Chris W Chronister, Barry K Logan, Bruce A Goldberger. Case Report: Synthetic Cannabinoid Deaths in State of Florida Prisoners.
Journal of analytical toxicology.
2020 Apr; 44(3):298-300. doi:
10.1093/jat/bkz092. [PMID: 31776572] - Oya Yeter, Yeter Erol Öztürk. Detection and quantification of 5F-ADB and its methyl ester hydrolysis metabolite in fatal intoxication cases by liquid chromatography-high resolution mass spectrometry.
Forensic science international.
2019 Sep; 302(?):109866. doi:
10.1016/j.forsciint.2019.06.024. [PMID: 31302415] - Michael Kraemer, Helena Fels, Torsten Dame, Frank Musshoff, Sebastian Halter, Lukas Mogler, Cornelius Hess, Burkhard Madea, Alexandra Maas. Mono-/polyintoxication with 5F-ADB: A case series.
Forensic science international.
2019 Aug; 301(?):e29-e37. doi:
10.1016/j.forsciint.2019.05.017. [PMID: 31138461] - Oya Yeter, Yeter Erol Ozturk. Metabolic profiling of synthetic cannabinoid 5F-ADB by human liver microsome incubations and urine samples using high-resolution mass spectrometry.
Drug testing and analysis.
2019 Jun; 11(6):847-858. doi:
10.1002/dta.2566. [PMID: 30610752] - Ivo D Ivanov, Silviya Stoykova, Elka Ivanova, Aleksandrina Vlahova, Nikola Burdzhiev, Ivayla Pantcheva, Vasil N Atanasov. A case of 5F-ADB / FUB-AMB abuse: Drug-induced or drug-related death?.
Forensic science international.
2019 Apr; 297(?):372-377. doi:
10.1016/j.forsciint.2019.02.005. [PMID: 30850157] - Lilian H J Richter, Hans H Maurer, Markus R Meyer. Metabolic fate of the new synthetic cannabinoid 7'N-5F-ADB in rat, human, and pooled human S9 studied by means of hyphenated high-resolution mass spectrometry.
Drug testing and analysis.
2019 Feb; 11(2):305-317. doi:
10.1002/dta.2493. [PMID: 30160067]
