Tris(2-carboxyethyl)phosphine (BioDeep_00000174878)

   

human metabolite blood metabolite


代谢物信息卡片


3-[bis(2-carboxyethyl)phosphanyl]propanoic acid

化学式: C9H15O6P (250.060622)
中文名称: 3,3,3-膦三基三丙酸
谱图信息: 最多检出来源 Homo sapiens(blood) 5.56%

分子结构信息

SMILES: C(CP(CCC(=O)O)CCC(=O)O)C(=O)O
InChI: InChI=1S/C9H15O6P/c10-7(11)1-4-16(5-2-8(12)13)6-3-9(14)15/h1-6H2,(H,10,11)(H,12,13)(H,14,15)

描述信息

D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents

同义名列表

6 个代谢物同义名

3-[bis(2-carboxyethyl)phosphanyl]propanoic acid; 3,3,3-PHOSPHINETRIYLTRIPROPANOIC ACID; 3,3,3-Phosphinidynetrispropanoic acid; 3,3,3-Phosphinidynetrispropanoate; Tris(2-carboxyethyl)phosphine; TCEP



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Jesudass Sutha, Murugesh Gayathri, Mathan Ramesh. Chronic exposure to tris (2-chloroethyl) phosphate (TCEP) induces brain structural and functional changes in zebrafish (Danio rerio): A comparative study on the environmental and LC50 concentrations of TCEP. Environmental science and pollution research international. 2024 Mar; 31(11):16770-16781. doi: 10.1007/s11356-024-32154-y. [PMID: 38321284]
  • Zhi-Lang Lao, Dan Wu, Hui-Ru Li, Yi-Shan Liu, Long-Wei Zhang, Yu-Fei Feng, Xue-Yi Jiang, Dong-Wei Wu, Jun-Jie Hu, Guang-Guo Ying. Uptake mechanism, translocation, and transformation of organophosphate esters in water hyacinth (Eichhornia crassipes): A hydroponic study. Environmental pollution (Barking, Essex : 1987). 2024 Jan; 341(?):122933. doi: 10.1016/j.envpol.2023.122933. [PMID: 37977360]
  • Fengxiao Hu, Wen Li, Hongkai Wang, Hangke Peng, Jiabo He, Jieyu Ding, Weini Zhang. Environmentally relevant concentrations of tris (2-chloroethyl) phosphate (TCEP) induce hepatotoxicity in zebrafish (Danio rerio): a whole life-cycle assessment. Fish physiology and biochemistry. 2023 Nov; ?(?):. doi: 10.1007/s10695-023-01265-7. [PMID: 37950834]
  • Sen Yang, Junhong Wu, Heli Wang, Qian Yang, Huanheng Zhang, Lihua Yang, Dan Li, Yirong Deng, Yin Zhong, Ping'an Peng. New dechlorination products and mechanisms of tris(2-chloroethyl) phosphate by an anaerobic enrichment culture from a vehicle dismantling site. Environmental pollution (Barking, Essex : 1987). 2023 Oct; ?(?):122704. doi: 10.1016/j.envpol.2023.122704. [PMID: 37806429]
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  • Daqian Yang, Xiangjuan Wei, Boya Zhang, Ruijiao Zhu, Hailong Hu, Xingpei Fan, Haining Du, Xi Chen, Ziyi Zhang, Meimei Zhao, Yuri Oh, Ning Gu. Probiotics protect against hepatic steatosis in tris (2-chloroethyl) phosphate-induced metabolic disorder of mice via FXR signaling. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2022 Nov; 169(?):113440. doi: 10.1016/j.fct.2022.113440. [PMID: 36162615]
  • Daqian Yang, Xiangjuan Wei, Ziyi Zhang, Xi Chen, Ruijiao Zhu, Yuri Oh, Ning Gu. Tris (2-chloroethyl) phosphate (TCEP) induces obesity and hepatic steatosis via FXR-mediated lipid accumulation in mice: Long-term exposure as a potential risk for metabolic diseases. Chemico-biological interactions. 2022 Aug; 363(?):110027. doi: 10.1016/j.cbi.2022.110027. [PMID: 35780845]
  • Jesudass Sutha, Pottanthara Ashokan Anila, Murugesh Gayathri, Mathan Ramesh. Long term exposure to tris (2-chloroethyl) phosphate (TCEP) causes alterations in reproductive hormones, vitellogenin, antioxidant enzymes, and histology of gonads in zebrafish (Danio rerio): In vivo and computational analysis. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2022 Apr; 254(?):109263. doi: 10.1016/j.cbpc.2021.109263. [PMID: 35032655]
  • Jesudass Sutha, Pottanthara Ashokan Anila, Sathisaran Umamaheswari, Mathan Ramesh, Arul Narayanasamy, Rama-Krishnan Poopal, Zongming Ren. Biochemical responses of a freshwater fish Cirrhinus mrigala exposed to tris(2-chloroethyl) phosphate (TCEP). Environmental science and pollution research international. 2020 Sep; 27(27):34369-34387. doi: 10.1007/s11356-020-09527-0. [PMID: 32557019]
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  • Stefan Trapp, Trine Eggen. Simulation of the plant uptake of organophosphates and other emerging pollutants for greenhouse experiments and field conditions. Environmental science and pollution research international. 2013 Jun; 20(6):4018-29. doi: 10.1007/s11356-012-1337-7. [PMID: 23212267]
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