(Z)-7-[(1R,4S,5R,6S)-5-[(E,3R)-3-Hydroxyoct-1-enyl]-2-oxabicyclo[2.2.1]heptan-6-yl]hept-5-enoic acid (BioDeep_00000174854)

   

human metabolite blood metabolite


代谢物信息卡片


(Z)-7-[(1R,4S,5R,6S)-5-[(E,3R)-3-Hydroxyoct-1-enyl]-2-oxabicyclo[2.2.1]heptan-6-yl]hept-5-enoic acid

化学式: C21H34O4 (350.24569640000004)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(blood) 50%

分子结构信息

SMILES: CCCCCC(O)C=CC1C2COC(C2)C1CC=CCCCC(O)=O
InChI: InChI=1S/C21H34O4/c1-2-3-6-9-17(22)12-13-18-16-14-20(25-15-16)19(18)10-7-4-5-8-11-21(23)24/h4,7,12-13,16-20,22H,2-3,5-6,8-11,14-15H2,1H3,(H,23,24)

描述信息

同义名列表

4 个代谢物同义名

(Z)-7-[(1R,4S,5R,6S)-5-[(E,3R)-3-Hydroxyoct-1-enyl]-2-oxabicyclo[2.2.1]heptan-6-yl]hept-5-enoic acid; (Z)-7-[(1R,4S,5R,6S)-5-[(e,3R)-3-Hydroxyoct-1-enyl]-2-oxabicyclo[2.2.1]heptan-6-yl]hept-5-enoate; 7-[5-(3-hydroxyoct-1-en-1-yl)-2-oxabicyclo[2.2.1]heptan-6-yl]hept-5-enoic acid; 7-[5-(3-Hydroxyoct-1-en-1-yl)-2-oxabicyclo[2.2.1]heptan-6-yl]hept-5-enoate



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Aditi Das, Snehita Sri Varma, Christopher Mularczyk, Daryl D Meling. Functional investigations of thromboxane synthase (CYP5A1) in lipid bilayers of nanodiscs. Chembiochem : a European journal of chemical biology. 2014 Apr; 15(6):892-9. doi: 10.1002/cbic.201300646. [PMID: 24623680]
  • S R Bailey, J Elliott. Plasma 5-hydroxytryptamine constricts equine digital blood vessels in vitro: implications for pathogenesis of acute laminitis. Equine veterinary journal. 1998 Mar; 30(2):124-30. doi: 10.1111/j.2042-3306.1998.tb04471.x. [PMID: 9535068]
  • K Hayashi, R Loutzenhiser, M Epstein. Direct evidence that thromboxane mimetic U44069 preferentially constricts the afferent arteriole. Journal of the American Society of Nephrology : JASN. 1997 Jan; 8(1):25-31. doi: 10.1681/asn.v8125. [PMID: 9013445]
  • C F Teixeira, P Farmer, J Laporte, S Jancar, P Sirois. Increased permeability of bovine aortic endothelial cell monolayers in response to a thromboxane A2-mimetic. Agents and actions. Supplements. 1995; 45(?):47-52. doi: 10.1007/978-3-0348-7346-8_7. [PMID: 7717200]
  • M F Heath, R J Evans, A W Poole, L J Hayes, R J McEvoy, R M Littler. The effects of aspirin and paracetamol on the aggregation of equine blood platelets. Journal of veterinary pharmacology and therapeutics. 1994 Oct; 17(5):374-8. doi: 10.1111/j.1365-2885.1994.tb00262.x. [PMID: 7853463]
  • M G Sirois, W T de Lima, A J de Brum Fernandes, R J Johnson, G E Plante, P Sirois. Effect of PAF on rat lung vascular permeability: role of platelets and polymorphonuclear leucocytes. British journal of pharmacology. 1994 Apr; 111(4):1111-6. doi: 10.1111/j.1476-5381.1994.tb14859.x. [PMID: 8032597]
  • R Loutzenhiser, M Epstein. Renal microvascular actions of calcium antagonists. Journal of the American Society of Nephrology : JASN. 1990 Sep; 1(3 Suppl 1):S3-12. doi: NULL. [PMID: 16989072]
  • M Cirino, H Morton, C MacDonald, J Hadden, A W Ford-Hutchinson. Thromboxane A2 and prostaglandin endoperoxide analogue effects on porcine renal blood flow. The American journal of physiology. 1990 Jan; 258(1 Pt 2):F109-14. doi: 10.1152/ajprenal.1990.258.1.f109. [PMID: 2301587]
  • W Siess, E G Lapetina. Phorbol esters sensitize platelets to activation by physiological agonists. Blood. 1987 Nov; 70(5):1373-81. doi: NULL. [PMID: 3663938]
  • R Loutzenhiser, M Epstein, C Horton, P Sonke. Reversal of renal and smooth muscle actions of the thromboxane mimetic U-44069 by diltiazem. The American journal of physiology. 1986 Apr; 250(4 Pt 2):F619-26. doi: 10.1152/ajprenal.1986.250.4.f619. [PMID: 3963201]
  • D E MacIntyre, A M Shaw, M Bushfield, L J MacMillan, A McNicol, W K Pollock. Endogenous and pharmacological mechanisms for the regulation of human platelet cytosolic free Ca2+. Nouvelle revue francaise d'hematologie. 1985; 27(4):285-92. doi: ". [PMID: 2997706]
  • P R Gordon, J D Browning, B L O'Dell. Platelet arachidonate metabolism and platelet function in zinc-deficient rats. The Journal of nutrition. 1983 Apr; 113(4):766-72. doi: 10.1093/jn/113.4.766. [PMID: 6403678]
  • I L Smith, T J Martin. Platelet thromboxane synthesis and release reactions in myeloproliferative disorders. Haemostasis. 1982; 11(2):119-27. doi: 10.1159/000214650. [PMID: 6211399]
  • S Suzuki, R Franco-Saenz, S Y Tan, P J Mulrow. Direct action of prostaglandins on renin release from rat renal cortical slices. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 1981 Apr; 166(4):484-8. doi: 10.3181/00379727-166-41095. [PMID: 7012843]