Racephedrine (BioDeep_00000174813)

Main id: BioDeep_00000270888

Secondary id: BioDeep_00000600469

human metabolite blood metabolite Volatile Flavor Compounds natural product

代谢物信息卡片

2-(methylamino)-1-phenylpropan-1-ol

化学式: C10H15NO (165.115358)
中文名称: 2-(甲基氨基)-1-苯基-1-丙醇
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C(C1=CC=CC=C1)O)NC
InChI: InChI=1S/C10H15NO/c1-8(11-2)10(12)9-6-4-3-5-7-9/h3-8,10-12H,1-2H3

描述信息

同义名列表

4 个代谢物同义名

2-(methylamino)-1-phenylpropan-1-ol; pseudoephedrine, (-)-; Racephedrine; Racephedrine

数据库引用编号

8 个数据库交叉引用编号

PubChem: 5032
HMDB: HMDB0246924
ChEMBL: CHEMBL279157
Wikipedia: Ephedrine
chemspider: 4856
CAS: 53214-57-6
KEGG: C22822
LOTUS: LTS0074566

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

44 个相关的物种来源信息

3387 - Ephedra: 10.1007/S11418-011-0528-8
3387 - Ephedra: 10.1016/J.JEP.2015.01.043
3387 - Ephedra: LTS0074566
302008 - Ephedra ciliata: 10.1007/S11418-011-0528-8
302008 - Ephedra ciliata: 10.1016/J.JEP.2015.01.043
302008 - Ephedra ciliata: LTS0074566
3389 - Ephedra distachya: 10.1007/S11418-011-0528-8
3389 - Ephedra distachya: 10.1016/J.JEP.2015.01.043
3389 - Ephedra distachya: LTS0074566
288835 - Ephedra distachya subsp. helvetica: 10.1007/S11418-011-0528-8
288835 - Ephedra distachya subsp. helvetica: 10.1016/J.JEP.2015.01.043
288835 - Ephedra distachya subsp. helvetica: LTS0074566
173280 - Ephedra equisetina: 10.1007/S11418-011-0528-8
173280 - Ephedra equisetina: 10.1016/J.JEP.2015.01.043
173280 - Ephedra equisetina: LTS0074566
302007 - Ephedra foliata: 10.1007/S11418-011-0528-8
302007 - Ephedra foliata: 10.1016/J.JEP.2015.01.043
302007 - Ephedra foliata: LTS0074566
42328 - Ephedra gerardiana: 10.1007/S11418-011-0528-8
42328 - Ephedra gerardiana: 10.1016/J.JEP.2015.01.043
42328 - Ephedra gerardiana: LTS0074566
173278 - Ephedra intermedia: 10.1007/S11418-011-0528-8
173278 - Ephedra intermedia: 10.1016/J.JEP.2015.01.043
173278 - Ephedra intermedia: 10.1248/CPB.28.2900
173278 - Ephedra intermedia: LTS0074566
289842 - Ephedra pachyclada: 10.1007/S11418-011-0528-8
289842 - Ephedra pachyclada: 10.1016/J.JEP.2015.01.043
289842 - Ephedra pachyclada: LTS0074566
33152 - Ephedra sinica: 10.1007/S11418-011-0528-8
33152 - Ephedra sinica: 10.1016/J.JEP.2015.01.043
33152 - Ephedra sinica: 10.1021/JS9801844
33152 - Ephedra sinica: LTS0074566
3386 - Ephedraceae: LTS0074566
2759 - Eukaryota: LTS0074566
3372 - Gnetopsida: LTS0074566
9606 - Homo sapiens: -
3398 - Magnoliopsida: LTS0074566
3629 - Malvaceae: LTS0074566
77655 - Sida: LTS0074566
108362 - Sida cordifolia: 10.1016/0031-9422(75)83057-3
108362 - Sida cordifolia: LTS0074566
35493 - Streptophyta: LTS0074566
58023 - Tracheophyta: LTS0074566
33090 - Viridiplantae: LTS0074566

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

J-C He, E-F Feng, M Liu, H-L Li, M Tian, Q Zhang, L-C Dong, G-L Xu. Development and validation of a liquid chromatography-tandem mass spectrometry method for the simultaneous determination of acrivastine and pseudoephedrine in human plasma and its application in pharmacokinetics. Arzneimittel-Forschung. 2012 Oct; 62(10):449-56. doi: 10.1055/s-0032-1314877. [PMID: 22936420]
Zhijie Zheng, Tongmeng Yan, Weiying Chen, Ling Ye, Lan Tang, Zhongqiu Liu. Pharmacokinetic determination of ephedrine in Herba Ephedrae and Wu Tou Tang decoctions in rats using ultra performance liquid chromatography tandem mass spectrometry. Xenobiotica; the fate of foreign compounds in biological systems. 2012 Aug; 42(8):775-83. doi: 10.3109/00498254.2012.658884. [PMID: 22352390]
Yuejuan Zheng, Ziyi Guo, Weigang He, Yang Yang, Yuhu Li, Aoxiang Zheng, Ping Li, Yan Zhang, Jinzhu Ma, Mingyue Wen, Muyi Yang, Huazhang An, Guang Ji, Yizhi Yu. Ephedrine hydrochloride protects mice from LPS challenge by promoting IL-10 secretion and inhibiting proinflammatory cytokines. International immunopharmacology. 2012 May; 13(1):46-53. doi: 10.1016/j.intimp.2012.03.005. [PMID: 22446503]
Li-ping Yu, Xiao-ke Wang, Jia-bo Luo. [Determination of ephedrine hydrochloride, pseudoephedrine hydrochloride and methylephedrine hydrochloride in maxingshigan decoction by CE]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2011 Apr; 34(4):620-3. doi: ". [PMID: 21809550]
Raz Krizevski, Einat Bar, Or Shalit, Yaron Sitrit, Shimon Ben-Shabat, Efraim Lewinsohn. Composition and stereochemistry of ephedrine alkaloids accumulation in Ephedra sinica Stapf. Phytochemistry. 2010 Jun; 71(8-9):895-903. doi: 10.1016/j.phytochem.2010.03.019. [PMID: 20417943]
Hong-Gang Lou, Hong Yuan, Zou-Rong Ruan, Bo Jiang. Simultaneous determination of paracetamol, pseudoephedrine, dextrophan and chlorpheniramine in human plasma by liquid chromatography-tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2010 Mar; 878(7-8):682-8. doi: 10.1016/j.jchromb.2010.01.005. [PMID: 20133213]
Lei Zhang, Wentao Liu, Ruowen Zhang, Zhiwei Wang, Zhenduo Shen, Xiaohui Chen, Kaishun Bi. Pharmacokinetic study of matrine, oxymatrine and oxysophocarpine in rat plasma after oral administration of Sophora flavescens Ait. extract by liquid chromatography tandem mass spectrometry. Journal of pharmaceutical and biomedical analysis. 2008 Aug; 47(4-5):892-8. doi: 10.1016/j.jpba.2008.03.019. [PMID: 18479880]
Conrad E Johanson, John A Duncan, Petra M Klinge, Thomas Brinker, Edward G Stopa, Gerald D Silverberg. Multiplicity of cerebrospinal fluid functions: New challenges in health and disease. Cerebrospinal fluid research. 2008 May; 5(?):10. doi: 10.1186/1743-8454-5-10. [PMID: 18479516]
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Y Dhungana, B K Bhattarai, U K Bhadani, B K Biswas, M Tripathi. Prevention of hypotension during propofol induction: a comparison of preloading with 3.5\% polymers of degraded gelatin (Haemaccel) and intravenous ephedrine. Nepal Medical College journal : NMCJ. 2008 Mar; 10(1):16-9. doi: NULL. [PMID: 18700624]
Pei-Hong Mao, Xiang-Dong Ma, Xiang Jin, Hong-Mei Yang, Kai Lou. [Production of l-ephedrine and d-pseudoephedrine in recombined yeasts obtained by argon ion implantation mediated Ephedra genome DNA transformation]. Wei sheng wu xue bao = Acta microbiologica Sinica. 2007 Oct; 47(5):905-9. doi: ". [PMID: 18062271]
Marcello Cocuzza, Ashok Agarwal. Nonsurgical treatment of male infertility: specific and empiric therapy. Biologics : targets & therapy. 2007 Sep; 1(3):259-69. doi: NULL. [PMID: 19707335]
Toshiaki Nagai, Masahito Kido, Junko Maeda, Kazumi Matsushima, Toshio Okazaki, Akira Kurosu, Masahito Hitosugi, Shougo Tokudome. Stereoisomeric identification of norephedrine derived from methamphetamine or amphetamine: urinalysis results of 33 methamphetamine abusers and 1 amphetamine abuser in Japan. Analytical chemistry. 2007 Jun; 79(11):4177-81. doi: 10.1021/ac062229o. [PMID: 17451226]
Shuang-feng Lin, Xue-hong Ke, Gang Wei. [Investigate into of effective constituent transference of herba Ephedrae and cortex Magnoliae officinalis in preparation course of Shujin Kechuan capsule]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2006 Dec; 31(23):1950-2. doi: . [PMID: 17348186]
Shuang Ren, Xiao-yan Chen, Xiao-tao Duan, Da-fang Zhong. [Simultaneous determination of ephedrine and chlorpheniramine in human plasma by a highly sensitive liquid chromatography-tandem mass spectrometric method]. Yao xue xue bao = Acta pharmaceutica Sinica. 2006 Feb; 41(2):188-92. doi: NULL. [PMID: 16671554]
Huaifang Fang, Mingming Liu, Zhaorui Zeng. Solid-phase microextraction coupled with capillary electrophoresis to determine ephedrine derivatives in water and urine using a sol-gel derived butyl methacrylate/silicone fiber. Talanta. 2006 Jan; 68(3):979-86. doi: 10.1016/j.talanta.2005.06.062. [PMID: 18970420]
Jinchang Huang, Yu Xu, Fei Liu, Shu Gao, Qingxiang Guo. Development of a liquid chromatography/tandem mass spectrometry assay for the quantification of lisinopril in human plasma. Rapid communications in mass spectrometry : RCM. 2006; 20(2):248-52. doi: 10.1002/rcm.2309. [PMID: 16345121]
Hafid Belhadj-Tahar, Nouredine Sadeg. Methcathinone: a new postindustrial drug. Forensic science international. 2005 Oct; 153(1):99-101. doi: 10.1016/j.forsciint.2005.04.023. [PMID: 15919169]
Jianguo Sun, Guangji Wang, Wei Wang, Shuai Zhao, Yi Gu, Jinwen Zhang, Mingwen Huang, Fen Shao, Hao Li, Qi Zhang, Haitang Xie. Simultaneous determination of loratadine and pseudoephedrine sulfate in human plasma by liquid chromatography-electrospray mass spectrometry for pharmacokinetic studies. Journal of pharmaceutical and biomedical analysis. 2005 Sep; 39(1-2):217-24. doi: 10.1016/j.jpba.2005.03.041. [PMID: 15953705]
Li-Bin Liu, Zhi-Xia Zheng, Jin-Ming Lin. Application of dimethyl-beta-cyclodextrin as a chiral selector in capillary electrophoresis for enantiomer separation of ephedrine and related compounds in some drugs. Biomedical chromatography : BMC. 2005 Jul; 19(6):447-53. doi: 10.1002/bmc.504. [PMID: 16037931]
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Khalidah Aljazaf, Thomas W Hale, Kenneth F Ilett, Peter E Hartmann, Leon R Mitoulas, Judith H Kristensen, L Peter Hackett. Pseudoephedrine: effects on milk production in women and estimation of infant exposure via breastmilk. British journal of clinical pharmacology. 2003 Jul; 56(1):18-24. doi: 10.1046/j.1365-2125.2003.01822.x. [PMID: 12848771]
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