5,6-Dihydro-1,10-phenanthroline (BioDeep_00000174766)

   

human metabolite blood metabolite


代谢物信息卡片


1,10-Phenanthroline monohydrochoride

化学式: C12H10N2 (182.0844)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(blood) 1.77%

分子结构信息

SMILES: C1CC2=C(C3=C1C=CC=N3)N=CC=C2
InChI: InChI=1S/C12H10N2/c1-3-9-5-6-10-4-2-8-14-12(10)11(9)13-7-1/h1-4,7-8H,5-6H2

描述信息

D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D002800 - Cholinesterase Inhibitors
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D003432 - Cross-Linking Reagents
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D007364 - Intercalating Agents
D064449 - Sequestering Agents > D002614 - Chelating Agents > D007502 - Iron Chelating Agents
D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors

同义名列表

11 个代谢物同义名

1,10-Phenanthroline monohydrochoride; 1,10-Phenanthroline monoperchlorate; 1,10-Phenanthroline hydrochoride; 5,6-Dihydro-1,10-phenanthroline; 1,10-Phenanthroline, zinc salt; 1,10-Phenanthroline hydrate; Copper phenanthroline; 1,10-phenanthroline; O-Phenanthroline; (OP)2Cu(I); O-PHE



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Yu Wang, Zhouhui Wu, Zhiwen Wang, Heng Du, Shuang Xiao, Lin Lu, Zhen Wang. Analyses of the Antibiofilm Activity of o-Phenanthroline Monohydrate against Enterococcus faecalis and Staphylococcus aureus and the Mechanisms Underlying These Effects. ACS infectious diseases. 2024 Feb; 10(2):638-649. doi: 10.1021/acsinfecdis.3c00516. [PMID: 38258383]
  • Anđela Bačinić, Sanja Frka, Marina Mlakar. A study of cobalt (II) complexes involved in marine biogeochemical processes: Co(II)-1,10-Phenanthroline and Co(II)-1,10-Phenanthroline-L-α-Phosphatidylcholine. Bioelectrochemistry (Amsterdam, Netherlands). 2022 Apr; 144(?):108009. doi: 10.1016/j.bioelechem.2021.108009. [PMID: 34902665]
  • Geraldine Backman-Blanco, Hugo Valdés, María Teresa Ramírez-Apan, Patricia Cano-Sanchez, Simón Hernandez-Ortega, Adrian L Orjuela, Jorge Alí-Torres, Areli Flores-Gaspar, Reyna Reyes-Martínez, David Morales-Morales. Synthesis of Pt(II) complexes of the type [Pt(1,10-phenanthroline)(SArFn)2] (SArFn = SC6H3-3,4-F2; SC6F4-4-H; SC6F5). Preliminary evaluation of their in vitro anticancer activity. Journal of inorganic biochemistry. 2020 10; 211(?):111206. doi: 10.1016/j.jinorgbio.2020.111206. [PMID: 32801098]
  • Sebastiano Masuri, Enzo Cadoni, Maria Grazia Cabiddu, Francesco Isaia, Maria Giovanna Demuru, Lukáš Moráň, David Buček, Petr Vaňhara, Josef Havel, Tiziana Pivetta. The first copper(ii) complex with 1,10-phenanthroline and salubrinal with interesting biochemical properties. Metallomics : integrated biometal science. 2020 06; 12(6):891-901. doi: 10.1039/d0mt00006j. [PMID: 32337526]
  • Masoomeh Shaghaghi, Samaneh Rashtbari, Asma Abdollahi, Gholamreza Dehghan, Abolghasem Jouyban. A Sensitive, Simple and Direct Determination of Pantoprazole Based on a 'Turn off-on' Fluorescence Nanosensor by Using Terbium-1,10-phenanthroline-silver Nanoparticles. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry. 2020; 36(11):1345-1352. doi: 10.2116/analsci.20p142. [PMID: 33177314]
  • Aarti Upadhyay, Srishti Gautam, Vanitha Ramu, Paturu Kondaiah, Akhil R Chakravarty. Photocytotoxic cancer cell-targeting platinum(ii) complexes of glucose-appended curcumin and biotinylated 1,10-phenanthroline. Dalton transactions (Cambridge, England : 2003). 2019 Dec; 48(47):17556-17565. doi: 10.1039/c9dt03490k. [PMID: 31748772]
  • Shohreh Jahani, Meissam Noroozifar, Mozhgan Khorasani-Motlagh, Masoud Torkzadeh-Mahani, Mahboubeh Adeli-Sardou. In vitro cytotoxicity studies of parent and nanoencapsulated Holmium-2,9-dimethyl-1,10-phenanthroline complex toward fish-salmon DNA-binding properties and antibacterial activity. Journal of biomolecular structure & dynamics. 2019 10; 37(17):4437-4449. doi: 10.1080/07391102.2018.1557077. [PMID: 30526398]
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  • Ying Xiao, Qing Wang, Yanmei Huang, Xiangling Ma, Xinnuo Xiong, Hui Li. Synthesis, structure, and biological evaluation of a copper(ii) complex with fleroxacin and 1,10-phenanthroline. Dalton transactions (Cambridge, England : 2003). 2016 Jul; 45(27):10928-35. doi: 10.1039/c6dt00915h. [PMID: 27301999]
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  • Chew Hee Ng, Cheang Wei Chan, Jing Wei Lai, Ing Hong Ooi, Kok Vei Chong, Mohd Jamil Maah, Hoi Ling Seng. Enantiomeric pair of copper(II) polypyridyl-alanine complexes: Effect of chirality on their interaction with biomolecules. Journal of inorganic biochemistry. 2016 07; 160(?):1-11. doi: 10.1016/j.jinorgbio.2016.04.003. [PMID: 27105312]
  • Veysel T Yilmaz, Ceyda Icsel, Feruza Suyunova, Muhittin Aygun, Nazlihan Aztopal, Engin Ulukaya. Ni(ii)/Cu(ii)/Zn(ii) 5,5-diethylbarbiturate complexes with 1,10-phenanthroline and 2,2'-dipyridylamine: synthesis, structures, DNA/BSA binding, nuclease activity, molecular docking, cellular uptake, cytotoxicity and the mode of cell death. Dalton transactions (Cambridge, England : 2003). 2016 Jun; 45(25):10466-79. doi: 10.1039/c6dt01726f. [PMID: 27263797]
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