Methyl N-methylanthranilate (BioDeep_00000017467)

 

Secondary id: BioDeep_00000227497, BioDeep_00000618889, BioDeep_00000862735

human metabolite PANOMIX_OTCML-2023


代谢物信息卡片


BENZOIC ACID METHYL ESTER,2-METHYLAMINO (N-METHYL-ANTHRANILIC ACID METHYL ESTER)

化学式: C9H11NO2 (165.0789746)
中文名称: N-甲基邻氨基苯甲酸甲酯, 邻甲氨基苯甲酸甲酯, 2-(甲氨基)苯甲酸甲酯
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 29.17%

分子结构信息

SMILES: CNC1=CC=CC=C1C(=O)OC
InChI: InChI=1S/C9H11NO2/c1-10-8-6-4-3-5-7(8)9(11)12-2/h3-6,10H,1-2H3

描述信息

Methyl N-methylanthranilate is a methyl ester resulting from the formal condensation of the carboxy group of N-methylanthranilic acid with methanol. It has a role as a fungal metabolite, a plant metabolite and an animal metabolite. It is a benzoate ester, a methyl ester, a secondary amino compound and a substituted aniline. It is functionally related to a N-methylanthranilic acid.
Methyl 2-(methylamino)benzoate is a natural product found in Zanthoxylum beecheyanum, Mangifera indica, and other organisms with data available.
See also: Mandarin oil (part of).
Methyl N-methylanthranilate is found in citrus. Methyl N-methylanthranilate is a constituent of mandarin peel oil (Citrus madurensis), petitgrain oil and other citrus species oils. Methyl N-methylanthranilate is a flavouring agent.
Constituent of mandarin peel oil (Citrus madurensis), petitgrain oil and other citrus subspecies oils. Flavouring agent. Methyl N-methylanthranilate is found in sweet orange and citrus.
A methyl ester resulting from the formal condensation of the carboxy group of N-methylanthranilic acid with methanol.
Methyl N-methylanthranilate, a terpene, is a pungent compound that can be found in Citrus reticulate Blanco leaves. Methyl N-methylanthranilate has the potential for pain research[1].
Methyl N-methylanthranilate, a terpene, is a pungent compound that can be found in Citrus reticulate Blanco leaves. Methyl N-methylanthranilate has the potential for pain research[1].

同义名列表

57 个代谢物同义名

BENZOIC ACID METHYL ESTER,2-METHYLAMINO (N-METHYL-ANTHRANILIC ACID METHYL ESTER); InChI=1/C9H11NO2/c1-10-8-6-4-3-5-7(8)9(11)12-2/h3-6,10H,1-2H; Methyl N-methylanthranilate, technical, >=95.0\\% (GC); Benzoic acid, 2-(methylamino)-, methyl ester; Benzoic acid, o-(methylamino)-, methyl ester; (E)-ethyl 2-((4-acetylphenyl)imino)acetate; Dimethyl anthranilate, analytical standard; Dimethyl anthranilate, natural, >=98\\%, FG; Anthranilic acid, N-methyl-, methyl ester; N-Methyl-2-aminobenzoic Acid Methyl Ester; 2-(methylamino)benzoic acid methyl ester; 2-methylamino-benzoic acid methyl ester; N-Methylanthranilic acid, methyl ester; 2-Methylaminobenzoic acid methyl ester; N-Methylanthranilic Acid Methyl Ester; METHYL N-METHYL ANTHRANILATE [FHFI]; METHYL N-METHYLANTHRANILATE [HSDB]; Methyl 2-(methylamino)benzoic acid; 2-Methylaminobenzoate methyl ester; N-Methylanthranilate, methyl ester; Dimethyl anthranilate, >=97\\%, FG; Methyl N-methyl anthranylic acid; 2-Methylaminomethyl benzoic acid; Methyl-2-(N-methylamino)benzoate; Dimethyl anthranilate (natural); Methyl N-methylanthranilic acid; Methyl N-Methyl-2-aminobenzoate; Methyl N-methyl-o-anthranilate; Methyl benzoate, 2-methylamino; Methyl o-(methylamino)benzoate; Methyl methylaminobenzoic acid; Methyl 2-(methylamino)benzoate; Methyl2-(methylamino)benzoate; Methyl methylanthranilic acid; N-Methyl methyl anthranilate; Methyl N-methyl anthranilate; 2-Methylaminomethyl benzoate; methyl N-methyl anthranylate; methyl o-methylaminobenzoate; Methyl 2-methylaminobenzoate; Methyl methanthranilic acid; DIMETHYL ANTHRANILATE [FCC]; Methyl m-methylanthranilate; Methyl-N-methylanthranilate; Methyl N-methylanthranilate; Methyl methylaminobenzoate; Dimethyl anthranilic acid; Methyl methylanthranilate; Me N-methylanthranylate; Methyl methanthranilate; Me N-methylanthranilate; Dimethyl anthranilate; UNII-5Z37T562P9; WLN: 1OVR BM1; 5Z37T562P9; FEMA 2718; AI3-03340



数据库引用编号

13 个数据库交叉引用编号

分类词条

相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

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BioCyc(0)

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Plant Reactome(0)

INOH(0)

PlantCyc(0)

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12 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Ana B Miltojević, Nikola M Stojanović, Pavle J Randjelović, Niko S Radulović. Distribution of methyl and isopropyl N-methylanthranilates and their metabolites in organs of rats treated with these two essential-oil constituents. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2019 Jun; 128(?):68-80. doi: 10.1016/j.fct.2019.03.039. [PMID: 30914356]
  • Niko S Radulović, Ana B Miltojević, Nikola M Stojanović, Pavle J Randjelović. Distinct urinary metabolite profiles of two pharmacologically active N-methylanthranilates: Three approaches to xenobiotic metabolite identification. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2017 Nov; 109(Pt 1):341-355. doi: 10.1016/j.fct.2017.09.006. [PMID: 28888736]
  • Edwin Correa, Winston Quiñones, Fernando Echeverri. Methyl-N-methylanthranilate, a pungent compound from Citrus reticulata Blanco leaves. Pharmaceutical biology. 2016; 54(4):569-71. doi: 10.3109/13880209.2015.1044618. [PMID: 26471095]
  • Mariana Martins Gomes Pinheiro, Niko S Radulović, Ana B Miltojević, Fabio Boylan, Patrícia Dias Fernandes. Antinociceptive esters of N-methylanthranilic acid: Mechanism of action in heat-mediated pain. European journal of pharmacology. 2014 Mar; 727(?):106-14. doi: 10.1016/j.ejphar.2013.12.042. [PMID: 24486396]
  • Niko S Radulović, Ana B Miltojević, Pavle J Randjelović, Nikola M Stojanović, Fabio Boylan. Effects of methyl and isopropyl N-methylanthranilates from Choisya ternata Kunth (Rutaceae) on experimental anxiety and depression in mice. Phytotherapy research : PTR. 2013 Sep; 27(9):1334-8. doi: 10.1002/ptr.4877. [PMID: 23132808]
  • Mun Wai Cheong, Zhi Soon Chong, Shao Quan Liu, Weibiao Zhou, Philip Curran, Bin Yu. Characterisation of calamansi (Citrus microcarpa). Part I: volatiles, aromatic profiles and phenolic acids in the peel. Food chemistry. 2012 Sep; 134(2):686-95. doi: 10.1016/j.foodchem.2012.02.162. [PMID: 23107679]
  • Niko S Radulović, Ana B Miltojević, Michael McDermott, Steve Waldren, John Adrian Parnell, Mariana Martins Gomes Pinheiro, Patricia Dias Fernandes, Fabio de Sousa Menezes. Identification of a new antinociceptive alkaloid isopropyl N-methylanthranilate from the essential oil of Choisya ternata Kunth. Journal of ethnopharmacology. 2011 Jun; 135(3):610-9. doi: 10.1016/j.jep.2011.03.035. [PMID: 21420481]
  • C B Detoni, E C M Cabral-Albuquerque, S V A Hohlemweger, C Sampaio, T F Barros, E S Velozo. Essential oil from Zanthoxylum tingoassuiba loaded into multilamellar liposomes useful as antimicrobial agents. Journal of microencapsulation. 2009 Dec; 26(8):684-91. doi: 10.1080/02652040802661887. [PMID: 19888877]
  • Anne-Laure Gancel, Patrick Ollitrault, Yann Froelicher, Felix Tomi, Camille Jacquemond, Francois Luro, Jean-Marc Brillouet. Leaf volatile compounds of seven citrus somatic tetraploid hybrids sharing willow leaf mandarin (Citrus deliciosa Ten.) as their common parent. Journal of agricultural and food chemistry. 2003 Sep; 51(20):6006-13. doi: 10.1021/jf0345090. [PMID: 13129309]
  • D M Musher, D P Griffith, G B Templeton. Further observations on the potentiation of the antibacterial effect of methenamine by acetohydroxamic acid. The Journal of infectious diseases. 1976 May; 133(5):564-7. doi: 10.1093/infdis/133.5.564. [PMID: 4573]