Imidazoline (BioDeep_00000174534)

   

human metabolite blood metabolite


代谢物信息卡片


4,5-Dihydro-1H-imidazole

化学式: C3H6N2 (70.05309559999999)
中文名称: 2-咪唑啉
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1CN=CN1
InChI: InChI=1S/C3H6N2/c1-2-5-3-4-1/h3H,1-2H2,(H,4,5)

描述信息

同义名列表

4 个代谢物同义名

4,5-Dihydro-1H-imidazole; 2-Imidazoline; Imidazolines; Imidazoline



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Roberto I Cuevas-Hernández, Richard M B M Girard, Luka Krstulović, Miroslav Bajić, Ariel Mariano Silber. An aromatic imidazoline derived from chloroquinoline triggers cell cycle arrest and inhibits with high selectivity the Trypanosoma cruzi mammalian host-cells infection. PLoS neglected tropical diseases. 2021 11; 15(11):e0009994. doi: 10.1371/journal.pntd.0009994. [PMID: 34843481]
  • Ashley G Woolfork, Kyungah Suh, Miranda Weigand, David S Hage. Studies of binding by 2-imidazolines to human serum albumin and alpha1-acid glycoprotein by high-performance affinity chromatography. Journal of pharmaceutical and biomedical analysis. 2021 Aug; 202(?):114135. doi: 10.1016/j.jpba.2021.114135. [PMID: 34022667]
  • Huong Nguyen, Jia Yi Koh, Hainan Li, Argel Islas-Robles, Sai Pranathi Meda Venkata, Jie-Mei Wang, Terrence J Monks. A novel imidazolinone metformin-methylglyoxal metabolite promotes endothelial cell angiogenesis via the eNOS/HIF-1α pathway. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2021 07; 35(7):e21645. doi: 10.1096/fj.202002674rr. [PMID: 34105824]
  • Naotoshi Kanemitsu, Fumiko Kiyonaga, Kazuhiko Mizukami, Kyoichi Maeno, Takashi Nishikubo, Hiroyuki Yoshida, Hiroyuki Ito. Chronic treatment with the (iso-)glutaminyl cyclase inhibitor PQ529 is a novel and effective approach for glomerulonephritis in chronic kidney disease. Naunyn-Schmiedeberg's archives of pharmacology. 2021 04; 394(4):751-761. doi: 10.1007/s00210-020-02013-x. [PMID: 33159802]
  • Nguyen Thuan Dao, Reinhard Haselsberger, Mai Thu Khuc, Anh Tuân Phan, Alexander A Voityuk, Maria-Elisabeth Michel-Beyerle. Photophysics of DFHBI bound to RNA aptamer Baby Spinach. Scientific reports. 2021 04; 11(1):7356. doi: 10.1038/s41598-021-85091-y. [PMID: 33795733]
  • Ru-Ann Yean, Masilamany Dilipkumar, Sadequr Rahman, Beng-Kah Song. A Two-in-One Strategy: Target and Nontarget Site Mechanisms Both Play Important Role in IMI-Resistant Weedy Rice. International journal of molecular sciences. 2021 Jan; 22(3):. doi: 10.3390/ijms22030982. [PMID: 33498150]
  • Li-Xin Hu, Qian Xiong, Wen-Jun Shi, Guo-Yong Huang, You-Sheng Liu, Guang-Guo Ying. New insight into the negative impact of imidazolium-based ionic liquid [C10mim]Cl on Hela cells: From membrane damage to biochemical alterations. Ecotoxicology and environmental safety. 2021 Jan; 208(?):111629. doi: 10.1016/j.ecoenv.2020.111629. [PMID: 33396149]
  • Boris Dzikovski, Valery V Khramtsov, Siddarth Chandrasekaran, Curt Dunnam, Meera Shah, Jack H Freed. Microsecond Exchange Processes Studied by Two-Dimensional ESR at 95 GHz. Journal of the American Chemical Society. 2020 12; 142(51):21368-21381. doi: 10.1021/jacs.0c09469. [PMID: 33305945]
  • Jiuyuan Bai, Yao Luo, Xin Wang, Shi Li, Mei Luo, Meng Yin, Yuanli Zuo, Guolin Li, Junyu Yao, Hua Yang, Mingdi Zhang, Wei Wei, Maolin Wang, Rui Wang, Chunhai Fan, Yun Zhao. A protein-independent fluorescent RNA aptamer reporter system for plant genetic engineering. Nature communications. 2020 07; 11(1):3847. doi: 10.1038/s41467-020-17497-7. [PMID: 32737299]
  • Voraphoj Nilaratanakul, Debra A Hauer, Diane E Griffin. Development of encoded Broccoli RNA aptamers for live cell imaging of alphavirus genomic and subgenomic RNAs. Scientific reports. 2020 03; 10(1):5233. doi: 10.1038/s41598-020-61573-3. [PMID: 32251299]
  • Huirong Dong, Delin Wang, Zhijing Bai, Yuge Yuan, Wei Yang, Yuexia Zhang, Hanwen Ni, Linjian Jiang. Generation of imidazolinone herbicide resistant trait in Arabidopsis. PloS one. 2020; 15(5):e0233503. doi: 10.1371/journal.pone.0233503. [PMID: 32442184]
  • Mehdi Abedi, Samira Sadat Abolmaali, Mozhgan Abedanzadeh, Fatemeh Farjadian, Soliman Mohammadi Samani, Ali Mohammad Tamaddon. Core-Shell Imidazoline-Functionalized Mesoporous Silica Superparamagnetic Hybrid Nanoparticles as a Potential Theranostic Agent for Controlled Delivery of Platinum(II) Compound. International journal of nanomedicine. 2020; 15(?):2617-2631. doi: 10.2147/ijn.s245135. [PMID: 32368044]
  • Gaëlle Aubertin, Maud Weiss, Florian Traversi, Djamil Benameur, Philippe Choquet, Nassim Dali-Youcef, Françoise Pons, Séverine Sigrist, Hugues Greney, Laurent Monassier, Pascal Bousquet, Nathalie Niederhoffer. Effects of imidazoline-like drugs on liver and adipose tissues, and their role in preventing obesity and associated cardio-metabolic disorders. International journal of obesity (2005). 2019 11; 43(11):2163-2175. doi: 10.1038/s41366-019-0342-z. [PMID: 30926950]
  • Heather Wilson, George Dervenoulas, Gennaro Pagano, Robin J Tyacke, Sotirios Polychronis, Jim Myers, Roger N Gunn, Eugenii A Rabiner, David Nutt, Marios Politis. Imidazoline 2 binding sites reflecting astroglia pathology in Parkinson's disease: an in vivo11C-BU99008 PET study. Brain : a journal of neurology. 2019 10; 142(10):3116-3128. doi: 10.1093/brain/awz260. [PMID: 31504212]
  • Jaba Mitra, Taekjip Ha. Nanomechanics and co-transcriptional folding of Spinach and Mango. Nature communications. 2019 09; 10(1):4318. doi: 10.1038/s41467-019-12299-y. [PMID: 31541108]
  • Xiaohua Qi, Qianqian Li, Xiaotian Ma, Chunlu Qian, Huihui Wang, Nannan Ren, Chenxi Shen, Shumiao Huang, Xuewen Xu, Qiang Xu, Xuehao Chen. Waterlogging-induced adventitious root formation in cucumber is regulated by ethylene and auxin through reactive oxygen species signalling. Plant, cell & environment. 2019 05; 42(5):1458-1470. doi: 10.1111/pce.13504. [PMID: 30556134]
  • Kalyan Santra, Ivan Geraskin, Marit Nilsen-Hamilton, George A Kraus, Jacob W Petrich. Characterization of the Photophysical Behavior of DFHBI Derivatives: Fluorogenic Molecules that Illuminate the Spinach RNA Aptamer. The journal of physical chemistry. B. 2019 03; 123(11):2536-2545. doi: 10.1021/acs.jpcb.8b11166. [PMID: 30807171]
  • Kazunori Kawamura, Tomoteru Yamasaki, Yiding Zhang, Hidekatsu Wakizaka, Akiko Hatori, Lin Xie, Masayuki Fujinaga, Ming-Rong Zhang. Change in the Binding of [11C]BU99008 to Imidazoline I2 Receptor Using Brain PET in Zucker Rats. Molecular imaging and biology. 2019 02; 21(1):105-112. doi: 10.1007/s11307-018-1206-y. [PMID: 29736564]
  • Dmitry Dar'in, Vladimir Zarubaev, Anastasia Galochkina, Maxim Gureev, Mikhail Krasavin. Non-chelating p-phenylidene-linked bis-imidazoline analogs of known influenza virus endonuclease inhibitors: Synthesis and anti-influenza activity. European journal of medicinal chemistry. 2019 Jan; 161(?):526-532. doi: 10.1016/j.ejmech.2018.10.063. [PMID: 30390440]
  • Robin J Tyacke, Jim F M Myers, Ashwin Venkataraman, Inge Mick, Samuel Turton, Jan Passchier, Stephen M Husbands, Eugenii A Rabiner, Roger N Gunn, Philip S Murphy, Christine A Parker, David J Nutt. Evaluation of 11C-BU99008, a PET Ligand for the Imidazoline2 Binding Site in Human Brain. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2018 10; 59(10):1597-1602. doi: 10.2967/jnumed.118.208009. [PMID: 29523627]
  • Xin Tang, Ruijie Deng, Yupeng Sun, Xiaojun Ren, Mengxi Zhou, Jinghong Li. Amplified Tandem Spinach-Based Aptamer Transcription Enables Low Background miRNA Detection. Analytical chemistry. 2018 08; 90(16):10001-10008. doi: 10.1021/acs.analchem.8b02471. [PMID: 30016869]
  • Mohamed Farag, Wael M Abdel-Mageed, Omer Basudan, Ali El-Gamal. Persicaline, A New Antioxidant Sulphur-Containing Imidazoline Alkaloid from Salvadora persica Roots. Molecules (Basel, Switzerland). 2018 Feb; 23(2):. doi: 10.3390/molecules23020483. [PMID: 29473845]
  • Shaopeng Wei, Li Li, Yaping Shu, Kun Zhao, Zhiqin Ji. Synthesis, antifungal and antitumor activity of two new types of imidazolin-2-ones. Bioorganic & medicinal chemistry. 2017 12; 25(24):6501-6510. doi: 10.1016/j.bmc.2017.10.033. [PMID: 29100733]
  • Dongyan Song, Guohai Wu, Patricia Vrinten, Xiao Qiu. Development of imidazolinone herbicide tolerant borage (Borago officinalis L.). Plant science : an international journal of experimental plant biology. 2017 Sep; 262(?):74-80. doi: 10.1016/j.plantsci.2017.05.012. [PMID: 28716422]
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  • Giovanni Caprioli, Valerio Mammoli, Massimo Ricciutelli, Gianni Sagratini, Massimo Ubaldi, Esi Domi, Laura Mennuni, Chiara Sabatini, Chiara Galimberti, Flora Ferrari, Chiara Milia, Eleonora Comi, Marco Lanza, Mario Giannella, Maria Pigini, Fabio Del Bello. Biological profile and bioavailability of imidazoline compounds on morphine tolerance modulation. European journal of pharmacology. 2015 Dec; 769(?):219-24. doi: 10.1016/j.ejphar.2015.11.021. [PMID: 26593429]
  • Charles M Marson, Christopher J Matthews, Stephen J Atkinson, Nermina Lamadema, N Shaun B Thomas. Potent and Selective Inhibitors of Histone Deacetylase-3 Containing Chiral Oxazoline Capping Groups and a N-(2-Aminophenyl)-benzamide Binding Unit. Journal of medicinal chemistry. 2015 Sep; 58(17):6803-18. doi: 10.1021/acs.jmedchem.5b00545. [PMID: 26287310]
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