4-Thiazolol, 2-mercapto- (BioDeep_00000174517)
human metabolite blood metabolite
代谢物信息卡片
4-hydroxy-2,3-dihydro-1,3-thiazole-2-thione
化学式: C3H3NOS2 (132.9656068)
中文名称:
谱图信息:
最多检出来源 Danio rerio(blood) 64.29%
分子结构信息
SMILES: C1=C(NC(=S)S1)O
InChI: InChI=1S/C3H3NOS2/c5-2-1-7-3(6)4-2/h1,5H,(H,4,6)
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
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Organic & biomolecular chemistry.
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Particle and fibre toxicology.
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Aging.
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Critical care medicine.
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Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences.
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Shock (Augusta, Ga.).
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Toxicology mechanisms and methods.
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Cytometry. Part A : the journal of the International Society for Analytical Cytology.
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American journal of physiology. Heart and circulatory physiology.
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Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
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Journal of plant physiology.
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Experimental neurology.
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PLoS pathogens.
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Clinical hemorheology and microcirculation.
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Cellular & molecular biology letters.
2009; 14(1):23-34. doi:
10.2478/s11658-008-0031-8. [PMID: 18839073] - Chie Ohmura, Hirotaka Watada, Kosuke Azuma, Tomoaki Shimizu, Akio Kanazawa, Fuki Ikeda, Tomoaki Yoshihara, Yoshio Fujitani, Takahisa Hirose, Yasushi Tanaka, Ryuzo Kawamori. Aldose reductase inhibitor, epalrestat, reduces lipid hydroperoxides in type 2 diabetes.
Endocrine journal.
2009; 56(1):149-56. doi:
10.1507/endocrj.k08e-237. [PMID: 18997444] - Craig B Webb, Kelly W McCord, David C Twedt. Assessment of oxidative stress in leukocytes and granulocyte function following oral administration of a silibinin-phosphatidylcholine complex in cats.
American journal of veterinary research.
2009 Jan; 70(1):57-62. doi:
10.2460/ajvr.70.1.57. [PMID: 19119949] - Jun Liang, Cheryl Clark-Dixon, Shaoxiao Wang, Todd R Flower, Tara Williams-Hart, Richard Zweig, Lucy C Robinson, Kelly Tatchell, Stephan N Witt. Novel suppressors of alpha-synuclein toxicity identified using yeast.
Human molecular genetics.
2008 Dec; 17(23):3784-95. doi:
10.1093/hmg/ddn276. [PMID: 18772193] - Victor P Bulgakov, Dmitry L Aminin, Yuri N Shkryl, Tatiana Y Gorpenchenko, Galina N Veremeichik, Pavel S Dmitrenok, Yuri N Zhuravlev. Suppression of reactive oxygen species and enhanced stress tolerance in Rubia cordifolia cells expressing the rolC oncogene.
Molecular plant-microbe interactions : MPMI.
2008 Dec; 21(12):1561-70. doi:
10.1094/mpmi-21-12-1561. [PMID: 18986252] - Vicky Lahaie-Collins, Julie Bournival, Marilyn Plouffe, Julie Carange, Maria-Grazia Martinoli. Sesamin modulates tyrosine hydroxylase, superoxide dismutase, catalase, inducible NO synthase and interleukin-6 expression in dopaminergic cells under MPP+-induced oxidative stress.
Oxidative medicine and cellular longevity.
2008 Oct; 1(1):54-62. doi:
10.4161/oxim.1.1.6958. [PMID: 19794909] - Osamu Handa, Jancy Stephen, Gediminas Cepinskas. Role of endothelial nitric oxide synthase-derived nitric oxide in activation and dysfunction of cerebrovascular endothelial cells during early onsets of sepsis.
American journal of physiology. Heart and circulatory physiology.
2008 Oct; 295(4):H1712-9. doi:
10.1152/ajpheart.00476.2008. [PMID: 18723768] - Rabea Asleh, Shany Blum, Shiri Kalet-Litman, Jonia Alshiek, Rachel Miller-Lotan, Roy Asaf, Wasseem Rock, Michael Aviram, Uzi Milman, Chen Shapira, Zaid Abassi, Andrew P Levy. Correction of HDL dysfunction in individuals with diabetes and the haptoglobin 2-2 genotype.
Diabetes.
2008 Oct; 57(10):2794-800. doi:
10.2337/db08-0450. [PMID: 18599520] - Preeti Dohare, Puja Garg, Uma Sharma, N R Jagannathan, Madhur Ray. Neuroprotective efficacy and therapeutic window of curcuma oil: in rat embolic stroke model.
BMC complementary and alternative medicine.
2008 Sep; 8(?):55. doi:
10.1186/1472-6882-8-55. [PMID: 18826584] - Hyun Ah Jung, Na Young Yoon, Sam Sik Kang, Yeong Sik Kim, Jae Sue Choi. Inhibitory activities of prenylated flavonoids from Sophora flavescens against aldose reductase and generation of advanced glycation endproducts.
The Journal of pharmacy and pharmacology.
2008 Sep; 60(9):1227-36. doi:
10.1211/jpp.60.9.0016. [PMID: 18718128] - David Kessel, Michael Price, John J Reiners. The Bcl-2 antagonist HA14-1 forms a fluorescent albumin complex that can be mistaken for several oxidized ROS probes.
Photochemistry and photobiology.
2008 Sep; 84(5):1272-6. doi:
10.1111/j.1751-1097.2008.00371.x. [PMID: 18513234] - Rubina Soomro, M Jamaluddin Ahmed, Najma Memon, Humaira Khan. A simple and selective spectrophotometric method for the determination of trace gold in real, environmental, biological, geological and soil samples using bis (salicylaldehyde) orthophenylenediamine.
Analytical chemistry insights.
2008 Aug; 3(?):75-90. doi:
10.4137/aci.s977. [PMID: 19609392] - Björn Jüttner, Janina Kröplin, Sina M Coldewey, Lars Witt, Wilhelm A Osthaus, Christian Weilbach, Dirk Scheinichen. Unsaturated long-chain fatty acids induce the respiratory burst of human neutrophils and monocytes in whole blood.
Nutrition & metabolism.
2008 Jul; 5(?):19. doi:
10.1186/1743-7075-5-19. [PMID: 18625045] - Xavier Marechal, Raphael Favory, Olivier Joulin, David Montaigne, Sidi Hassoun, Brigitte Decoster, Farid Zerimech, Remi Neviere. Endothelial glycocalyx damage during endotoxemia coincides with microcirculatory dysfunction and vascular oxidative stress.
Shock (Augusta, Ga.).
2008 May; 29(5):572-6. doi:
10.1097/shk.0b013e318157e926. [PMID: 18414231] - Wansu Park, Mun Seog Chang, Hocheol Kim, Ho Young Choi, Woong Mo Yang, Do Rim Kim, Eun Hwa Park, Seong Kyu Park. Cytotoxic effect of gallic acid on testicular cell lines with increasing H2O2 level in GC-1 spg cells.
Toxicology in vitro : an international journal published in association with BIBRA.
2008 Feb; 22(1):159-63. doi:
10.1016/j.tiv.2007.08.010. [PMID: 17920234] - Hilde Grindvik Nielsen, Ole Henning Skjønsberg, Torstein Lyberg. Effect of antioxidant supplementation on leucocyte expression of reactive oxygen species in athletes.
Scandinavian journal of clinical and laboratory investigation.
2008; 68(7):526-33. doi:
10.1080/00365510701864602. [PMID: 19378423] - Ji-Ying Yang, Kai Sun, Chuan-She Wang, Jun Guo, Xin Xue, Yu-Ying Liu, Jun Zheng, Jing-Yu Fan, Fu-Long Liao, Jing-Yan Han. Improving effect of post-treatment with Panax notoginseng saponins on lipopolysaccharide-induced microcirculatory disturbance in rat mesentery.
Clinical hemorheology and microcirculation.
2008; 40(2):119-31. doi:
10.3233/ch-2008-1122. [PMID: 19029637] - Sergio Roa, Maria Isidoro-Garcia, Ignacio Davila, Elena Laffond, Felix Lorente, Rogelio Gonzalez-Sarmiento. Molecular analysis of activation-induced cytidine deaminase gene in immunoglobulin-E deficient patients.
Clinical & developmental immunology.
2008; 2008(?):146715. doi:
10.1155/2008/146715. [PMID: 19266080] - Dongwon Baek, Yinhua Jin, Jae Cheol Jeong, Hyo-Jung Lee, Haejeong Moon, Jiyoung Lee, Dongjin Shin, Chang Ho Kang, Doh Hoon Kim, Jaesung Nam, Sang Yeol Lee, Dae-Jin Yun. Suppression of reactive oxygen species by glyceraldehyde-3-phosphate dehydrogenase.
Phytochemistry.
2008 Jan; 69(2):333-8. doi:
10.1016/j.phytochem.2007.07.027. [PMID: 17854848] - Qing Liu, Yue-yun Zhang, Hui-li Lu, Qun-yi Li, Cai-hong Zhou, Ming-wei Wang. Rhodanine derivatives as novel peroxisome proliferator-activated receptor gamma agonists.
Acta pharmacologica Sinica.
2007 Dec; 28(12):2033-9. doi:
. [PMID: 18031620] - Philippe Villain-Guillot, Maxime Gualtieri, Lionel Bastide, Françoise Roquet, Jean Martinez, Muriel Amblard, Martine Pugniere, Jean-Paul Leonetti. Structure-activity relationships of phenyl-furanyl-rhodanines as inhibitors of RNA polymerase with antibacterial activity on biofilms.
Journal of medicinal chemistry.
2007 Aug; 50(17):4195-204. doi:
10.1021/jm0703183. [PMID: 17665895] - Guan-Jhong Huang, Ming-Jyh Sheu, Hsien-Jung Chen, Yuan-Shiun Chang, Yaw-Huei Lin. Inhibition of reactive nitrogen species in vitro and ex vivo by trypsin inhibitor from sweet potato 'Tainong 57' storage roots.
Journal of agricultural and food chemistry.
2007 Jul; 55(15):6000-6. doi:
10.1021/jf0701786. [PMID: 17602566] - Lei Wang, Gong Muxin, Hiroshi Nishida, Chieko Shirakawa, Shinji Sato, Tetsuya Konishi. Psychological stress-induced oxidative stress as a model of sub-healthy condition and the effect of TCM.
Evidence-based complementary and alternative medicine : eCAM.
2007 Jun; 4(2):195-202. doi:
10.1093/ecam/nel080. [PMID: 17549236] - Nicholas J Cave, Robert C Backus, Stanley L Marks, Kirk C Klasing. Modulation of innate and acquired immunity by an estrogenic dose of genistein in gonadectomized cats.
Veterinary immunology and immunopathology.
2007 May; 117(1-2):42-54. doi:
10.1016/j.vetimm.2007.02.008. [PMID: 17382408] - P Soler-Palacín, C Margareto, P Llobet, O Asensio, M Hernández, I Caragol, T Español. Chronic granulomatous disease in pediatric patients: 25 years of experience.
Allergologia et immunopathologia.
2007 May; 35(3):83-9. doi:
10.1157/13106774. [PMID: 17594870] - Sebastian Luci, Beatrice Giemsa, Gerd Hause, Holger Kluge, Klaus Eder. Clofibrate treatment in pigs: effects on parameters critical with respect to peroxisome proliferator-induced hepatocarcinogenesis in rodents.
BMC pharmacology.
2007 Apr; 7(?):6. doi:
10.1186/1471-2210-7-6. [PMID: 17437637] - Alexander Kern, Franz S Hartner, Maria Freigassner, Julia Spielhofer, Cornelia Rumpf, Laura Leitner, Kai-Uwe Fröhlich, Anton Glieder. Pichia pastoris 'just in time' alternative respiration.
Microbiology (Reading, England).
2007 Apr; 153(Pt 4):1250-1260. doi:
10.1099/mic.0.2006/001404-0. [PMID: 17379734] - Georgios K Glantzounis, Sophie A Rocks, Hemant Sheth, Iona Knight, Henryk J Salacinski, Brian R Davidson, Paul G Winyard, Alexander M Seifalian. Formation and role of plasma S-nitrosothiols in liver ischemia-reperfusion injury.
Free radical biology & medicine.
2007 Mar; 42(6):882-92. doi:
10.1016/j.freeradbiomed.2006.12.020. [PMID: 17320770] - Hilde Grindvik Nielsen, Per Kristian Opstad, Torstein Lyberg. LeuCAM and reactive oxygen species during long-term exercise combined with sleep and energy deficiency.
Medicine and science in sports and exercise.
2007 Feb; 39(2):275-82. doi:
10.1249/01.mss.0000241648.07382.7c. [PMID: 17277591] - Luis F Carbonell, Julián Díaz, Isabel Hernández, Santiago Cuevas, Fernando Valero, Tomás Quesada, Francisco Fenoy, Miguel G Salom. N-acetylcysteine exerts protective effects and prevents lung redox imbalance and peroxynitrite generation in endotoxemic rats.
Medicinal chemistry (Shariqah (United Arab Emirates)).
2007 Jan; 3(1):29-34. doi:
10.2174/157340607779317580. [PMID: 17266621] - Vany Nascimento-Silva, Maria Augusta Arruda, Christina Barja-Fidalgo, Iolanda M Fierro. Aspirin-triggered lipoxin A4 blocks reactive oxygen species generation in endothelial cells: a novel antioxidative mechanism.
Thrombosis and haemostasis.
2007 Jan; 97(1):88-98. doi:
10.1160/th06-06-0315. [PMID: 17200775] - D Fröhlich, B Trabold, G Rothe, K Hoerauf, S Wittmann. Inhibition of the neutrophil oxidative response by propofol: preserved in vivo function despite in vitro inhibition.
European journal of anaesthesiology.
2006 Nov; 23(11):948-53. doi:
10.1017/s0265021506000822. [PMID: 16780613] - Qin Wei, Yan Li, Wenying Dong, Bin Du. Determination of protein in milk powder using 2-sulfophenylazo-rhodanine as a probe by the enhanced resonance Rayleigh light-scattering technique.
Journal of AOAC International.
2006 Sep; 89(5):1353-9. doi:
NULL. [PMID: 17042187]