4-Hydroxy-3-nitrophenyl acetate (BioDeep_00000174394)

   

human metabolite blood metabolite


代谢物信息卡片


4-Hydroxy-3-nitrophenyl acetic acid

化学式: C8H7NO5 (197.0324)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(blood) 93.89%

分子结构信息

SMILES: CC(=O)OC1=CC(=C(C=C1)O)[N+](=O)[O-]
InChI: InChI=1S/C8H7NO5/c1-5(10)14-6-2-3-8(11)7(4-6)9(12)13/h2-4,11H,1H3

描述信息

同义名列表

2 个代谢物同义名

4-Hydroxy-3-nitrophenyl acetic acid; 4-Hydroxy-3-nitrophenyl acetate



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Jennifer L Marshall, Yang Zhang, Lalit Pallan, Mei-Chi Hsu, Mahmood Khan, Adam F Cunningham, Ian C M MacLennan, Kai-Michael Toellner. Early B blasts acquire a capacity for Ig class switch recombination that is lost as they become plasmablasts. European journal of immunology. 2011 Dec; 41(12):3506-12. doi: 10.1002/eji.201141762. [PMID: 21932446]
  • Andrew L Rankin, Heather MacLeod, Sean Keegan, Tatyana Andreyeva, Leslie Lowe, Laird Bloom, Mary Collins, Cheryl Nickerson-Nutter, Deborah Young, Heath Guay. IL-21 receptor is critical for the development of memory B cell responses. Journal of immunology (Baltimore, Md. : 1950). 2011 Jan; 186(2):667-74. doi: 10.4049/jimmunol.0903207. [PMID: 21169545]
  • Yusuke Kishi, Yuichi Aiba, Tetsuya Higuchi, Koji Furukawa, Takeshi Tokuhisa, Toshitada Takemori, Takeshi Tsubata. Augmented antibody response with premature germinal center regression in CD40L transgenic mice. Journal of immunology (Baltimore, Md. : 1950). 2010 Jul; 185(1):211-9. doi: 10.4049/jimmunol.0901694. [PMID: 20505144]
  • Rika Ouchida, Tomohiro Kurosaki, Ji-Yang Wang. A role for lysosomal-associated protein transmembrane 5 in the negative regulation of surface B cell receptor levels and B cell activation. Journal of immunology (Baltimore, Md. : 1950). 2010 Jul; 185(1):294-301. doi: 10.4049/jimmunol.1000371. [PMID: 20519653]
  • Masayuki Oda, Susumu Uchiyama, Masanori Noda, Yoshinori Nishi, Maiko Koga, Kouta Mayanagi, Carol V Robinson, Kiichi Fukui, Yuji Kobayashi, Kosuke Morikawa, Takachika Azuma. Effects of antibody affinity and antigen valence on molecular forms of immune complexes. Molecular immunology. 2009 Dec; 47(2-3):357-64. doi: 10.1016/j.molimm.2009.09.009. [PMID: 19800690]
  • Thuc-vy L Le, Tea Hyun Kim, David D Chaplin. Intraclonal competition inhibits the formation of high-affinity antibody-secreting cells. Journal of immunology (Baltimore, Md. : 1950). 2008 Nov; 181(9):6027-37. doi: 10.4049/jimmunol.181.9.6027. [PMID: 18941192]
  • Gijs Hardenberg, Liesbeth van Bostelen, Michael Hahne, Jan Paul Medema. Thymus-independent class switch recombination is affected by APRIL. Immunology and cell biology. 2008 Aug; 86(6):530-4. doi: 10.1038/icb.2008.17. [PMID: 18362943]
  • Thomas Hoehn, Sylvia Janssen, Ali R Mani, Gernot Brauers, Kevin P Moore, Peter Schadewaldt, Ertan Mayatepek. Urinary excretion of the nitrotyrosine metabolite 3-nitro-4-hydroxyphenylacetic acid in preterm and term infants. Neonatology. 2008; 93(2):73-6. doi: 10.1159/000106783. [PMID: 17684421]
  • Biao Zheng, Kirsten Switzer, Ekaterina Marinova, Daniel Wansley, Shuhua Han. Correction of age-associated deficiency in germinal center response by immunization with immune complexes. Clinical immunology (Orlando, Fla.). 2007 Aug; 124(2):131-7. doi: 10.1016/j.clim.2007.04.017. [PMID: 17561442]
  • Kagefumi Todo, Kenji Miyake, Masaki Magari, Naoki Kanayama, Hitoshi Ohmori. Novel in vitro screening system for monoclonal antibodies using hypermutating chicken B cell library. Journal of bioscience and bioengineering. 2006 Nov; 102(5):478-81. doi: 10.1263/jbb.102.478. [PMID: 17189180]
  • Béatrice Blanchard-Fillion, Delphine Prou, Manuela Polydoro, David Spielberg, Elpida Tsika, Zeneng Wang, Stanley L Hazen, Michael Koval, Serge Przedborski, Harry Ischiropoulos. Metabolism of 3-nitrotyrosine induces apoptotic death in dopaminergic cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2006 Jun; 26(23):6124-30. doi: 10.1523/jneurosci.1038-06.2006. [PMID: 16763020]
  • Oliver Pabst, Thorsten Peters, Niklas Czeloth, Günter Bernhardt, Karin Scharffetter-Kochanek, Reinhold Förster. Cutting edge: egress of newly generated plasma cells from peripheral lymph nodes depends on beta 2 integrin. Journal of immunology (Baltimore, Md. : 1950). 2005 Jun; 174(12):7492-5. doi: 10.4049/jimmunol.174.12.7492. [PMID: 15944247]
  • Kai-Michael Toellner, Mahmood Khan, Daniel Man-Yuen Sze. Analysis of the germinal center reaction and in vivo long-lived plasma cells. Methods in molecular biology (Clifton, N.J.). 2004; 271(?):111-25. doi: 10.1385/1-59259-796-3:111. [PMID: 15146116]
  • Vanitha S Raman, Rama S Akondy, Satyajit Rath, Vineeta Bal, Anna George. Ligation of CD27 on B cells in vivo during primary immunization enhances commitment to memory B cell responses. Journal of immunology (Baltimore, Md. : 1950). 2003 Dec; 171(11):5876-81. doi: 10.4049/jimmunol.171.11.5876. [PMID: 14634097]
  • Ali R Mani, Ananth S Pannala, Nelson N Orie, Richard Ollosson, David Harry, Catherine A Rice-Evans, Kevin P Moore. Nitration of endogenous para-hydroxyphenylacetic acid and the metabolism of nitrotyrosine. The Biochemical journal. 2003 Sep; 374(Pt 2):521-7. doi: 10.1042/bj20030670. [PMID: 12797864]
  • Takeyuki Shimizu, Masayuki Oda, Takachika Azuma. Estimation of the relative affinity of B cell receptor by flow cytometry. Journal of immunological methods. 2003 May; 276(1-2):33-44. doi: 10.1016/s0022-1759(03)00068-1. [PMID: 12738357]
  • Josie Ursini-Siegel, Wenli Zhang, Anne Altmeyer, Eunice N Hatada, Richard K G Do, Hideo Yagita, Selina Chen-Kiang. TRAIL/Apo-2 ligand induces primary plasma cell apoptosis. Journal of immunology (Baltimore, Md. : 1950). 2002 Nov; 169(10):5505-13. doi: 10.4049/jimmunol.169.10.5505. [PMID: 12421926]
  • Adam F Cunningham, Padraic G Fallon, Mahmood Khan, Sonia Vacheron, Hans Acha-Orbea, Ian C M MacLennan, Andrew N McKenzie, Kai-Michael Toellner. Th2 activities induced during virgin T cell priming in the absence of IL-4, IL-13, and B cells. Journal of immunology (Baltimore, Md. : 1950). 2002 Sep; 169(6):2900-6. doi: 10.4049/jimmunol.169.6.2900. [PMID: 12218103]
  • D J Driver, L J McHeyzer-Williams, M Cool, D B Stetson, M G McHeyzer-Williams. Development and maintenance of a B220- memory B cell compartment. Journal of immunology (Baltimore, Md. : 1950). 2001 Aug; 167(3):1393-405. doi: 10.4049/jimmunol.167.3.1393. [PMID: 11466358]