4-Dimethylaminopyridine (BioDeep_00000174369)

   

human metabolite blood metabolite


代谢物信息卡片


N,N-dimethylpyridin-4-amine

化学式: C7H10N2 (122.084394)
中文名称: 4-二甲氨基吡啶
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CN(C)C1=CC=NC=C1
InChI: InChI=1S/C7H10N2/c1-9(2)7-3-5-8-6-4-7/h3-6H,1-2H3

描述信息

同义名列表

3 个代谢物同义名

N,N-dimethylpyridin-4-amine; 4-Dimethylaminopyridine; 4-DMAP



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Han-Bin Chen, Jiang-Tao Zhou, Yu-Hong Liu, Zhen-Biao Zhang, Ya-Xian Zhan, Zi-Ren Su, Hui-Fang Zeng. Synthesis of pogostone by one-step. Journal of Asian natural products research. 2017 Feb; 19(2):172-175. doi: 10.1080/10286020.2016.1184253. [PMID: 27243631]
  • Stalin Kondaveeti, Dharmesh R Chejara, A K Siddhanta. A facile one-pot synthesis of a fluorescent agarose-O-naphthylacetyl adduct with slow release properties. Carbohydrate polymers. 2013 Oct; 98(1):589-95. doi: 10.1016/j.carbpol.2013.06.046. [PMID: 23987386]
  • Chun-Chi Chen, Yung-Lin Yang, Chun-Lin Ou, Chih-Hung Chou, Chih-Chuang Liaw, Po-Chiao Lin. Direct monitoring of chemical transformations by combining thin layer chromatography with nanoparticle-assisted laser desorption/ionization mass spectrometry. The Analyst. 2013 Mar; 138(5):1379-85. doi: 10.1039/c2an36423a. [PMID: 23330148]
  • Dongfeng Wei, Yanxia Wei, Weidong Cheng, Lifeng Zhang. Sulfated modification, characterization and antitumor activities of Radix hedysari polysaccharide. International journal of biological macromolecules. 2012 Nov; 51(4):471-6. doi: 10.1016/j.ijbiomac.2012.06.004. [PMID: 22705472]
  • Junlong Wang, Baotang Zhao, Xiaofang Wang, Jian Yao, Ji Zhang. Structure and antioxidant activities of sulfated guar gum: homogeneous reaction using DMAP/DCC catalyst. International journal of biological macromolecules. 2012 Jun; 50(5):1201-6. doi: 10.1016/j.ijbiomac.2012.03.009. [PMID: 22484325]
  • Dongfeng Wei, Weidong Cheng, Yanxia Wei, Lifeng Zhang. Phosphorylated modification and in vitro antioxidant activity of Radix Hedysari polysaccharide. Glycoconjugate journal. 2012 May; 29(4):167-72. doi: 10.1007/s10719-012-9377-2. [PMID: 22535466]
  • Rahul S Kalhapure, Krishnacharya G Akamanchi. Oleic acid based heterolipid synthesis, characterization and application in self-microemulsifying drug delivery system. International journal of pharmaceutics. 2012 Apr; 425(1-2):9-18. doi: 10.1016/j.ijpharm.2012.01.004. [PMID: 22266534]
  • Xiangdong Su, Fabienne Pradaux-Caggiano, Nigel Vicker, Mark P Thomas, Heather Halem, Michael D Culler, Barry V L Potter. Adamantyl ethanone pyridyl derivatives: potent and selective inhibitors of human 11β-hydroxysteroid dehydrogenase type 1. ChemMedChem. 2011 Sep; 6(9):1616-29. doi: 10.1002/cmdc.201100182. [PMID: 21714097]
  • Alejandra León, María Isabel Chávez, Guillermo Delgado. (1)H and DOSY NMR spectroscopy analysis of Ligusticum porteri rhizome extracts. Magnetic resonance in chemistry : MRC. 2011 Aug; 49(8):469-76. doi: 10.1002/mrc.2767. [PMID: 21761449]
  • Lan Feng, Huali Wu, Ping Ma, Russell J Mumper, S Rahima Benhabbour. Development and optimization of oil-filled lipid nanoparticles containing docetaxel conjugates designed to control the drug release rate in vitro and in vivo. International journal of nanomedicine. 2011; 6(?):2545-56. doi: 10.2147/ijn.s24954. [PMID: 22072889]
  • Xiang Li, Xin Tian, Jing Zhang, Xu Zhao, Xiaohui Chen, Youhong Jiang, Dongkai Wang, Weisan Pan. In vitro and in vivo evaluation of folate receptor-targeting amphiphilic copolymer-modified liposomes loaded with docetaxel. International journal of nanomedicine. 2011; 6(?):1167-84. doi: 10.2147/ijn.s21445. [PMID: 21852896]
  • Zhongmei Tang, F Peter Guengerich. Dansylation of unactivated alcohols for improved mass spectral sensitivity and application to analysis of cytochrome P450 oxidation products in tissue extracts. Analytical chemistry. 2010 Sep; 82(18):7706-12. doi: 10.1021/ac1015497. [PMID: 20795636]
  • John H Grabber, Paul F Schatz, Hoon Kim, Fachuang Lu, John Ralph. Identifying new lignin bioengineering targets: 1. Monolignol-substitute impacts on lignin formation and cell wall fermentability. BMC plant biology. 2010 Jun; 10(?):114. doi: 10.1186/1471-2229-10-114. [PMID: 20565789]
  • Jessica Dawlaty, Xiaorong Zhang, Michael A Fischbach, Jon Clardy. Dapdiamides, tripeptide antibiotics formed by unconventional amide ligases. Journal of natural products. 2010 Mar; 73(3):441-6. doi: 10.1021/np900685z. [PMID: 20041689]
  • Maria Schubert, Anna N Melnikova, Nikola Mesecke, Elena K Zubkova, Rocco Fortte, Denis R Batashev, Inga Barth, Norbert Sauer, Yuri V Gamalei, Natalia S Mamushina, Lutz F Tietze, Olga V Voitsekhovskaja, Katharina Pawlowski. Two novel disaccharides, rutinose and methylrutinose, are involved in carbon metabolism in Datisca glomerata. Planta. 2010 Feb; 231(3):507-21. doi: 10.1007/s00425-009-1049-5. [PMID: 19915863]
  • Martin J Sergeant, Jian-Jun Li, Christine Fox, Nicola Brookbank, Dean Rea, Timothy D H Bugg, Andrew J Thompson. Selective inhibition of carotenoid cleavage dioxygenases: phenotypic effects on shoot branching. The Journal of biological chemistry. 2009 Feb; 284(8):5257-64. doi: 10.1074/jbc.m805453200. [PMID: 19098002]
  • Ying-Qian Liu, Xuan Tian, Liu Yang, Zong-Cheng Zhan. First synthesis of novel spin-labeled derivatives of camptothecin as potential antineoplastic agents. European journal of medicinal chemistry. 2008 Nov; 43(11):2610-4. doi: 10.1016/j.ejmech.2008.01.008. [PMID: 18313176]
  • Kouwa Yamashita, Mitsunobu Okuyama, Risa Nakagawa, Seijiro Honma, Fumitoshi Satoh, Ryo Morimoto, Sadayoshi Ito, Madoka Takahashi, Mitsuteru Numazawa. Development of sensitive derivatization method for aldosterone in liquid chromatography-electrospray ionization tandem mass spectrometry of corticosteroids. Journal of chromatography. A. 2008 Jul; 1200(2):114-21. doi: 10.1016/j.chroma.2008.05.034. [PMID: 18561939]
  • Jungyeon Hwang, Kathleen Rodgers, James C Oliver, Thomas Schluep. Alpha-methylprednisolone conjugated cyclodextrin polymer-based nanoparticles for rheumatoid arthritis therapy. International journal of nanomedicine. 2008; 3(3):359-71. doi: 10.2147/ijn.s3217. [PMID: 18990945]
  • Liping Song, Hui Li, Ulas Sunar, Juan Chen, Ian Corbin, Arjun G Yodh, Gang Zheng. Naphthalocyanine-reconstituted LDL nanoparticles for in vivo cancer imaging and treatment. International journal of nanomedicine. 2007; 2(4):767-74. doi: ". [PMID: 18203443]
  • Eric Yang, Sherry Wang, Chester Bowen, John Kratz, Matthew J Cyronak, Jacob R Dunbar. Trapping 4-fluorobenzyl chloride in human plasma with chemical derivatization followed by quantitative bioanalysis using high-performance liquid chromatography/tandem mass spectrometry. Rapid communications in mass spectrometry : RCM. 2005; 19(6):759-66. doi: 10.1002/rcm.1849. [PMID: 15712293]
  • Rafat A Siddiqui, Mustapha Zerouga, Min Wu, Alicia Castillo, Kevin Harvey, Gary P Zaloga, William Stillwell. Anticancer properties of propofol-docosahexaenoate and propofol-eicosapentaenoate on breast cancer cells. Breast cancer research : BCR. 2005; 7(5):R645-54. doi: 10.1186/bcr1036. [PMID: 16168109]
  • Sachiko Ikumi, Masatsugu Asada, Ken Sawai, Yutaka Fukui. Effect of activation methods for bovine oocytes after intracytoplasmic injection. The Journal of reproduction and development. 2003 Feb; 49(1):37-43. doi: 10.1262/jrd.49.37. [PMID: 14967947]
  • Cheng Zhi Huang, Tomofumi Santa, Kazuhiro Imai. Development of 7-(N,N-dimethylaminosulfonyl)-5-N-(4-N-aminoethyl)piperazino-2,1,3-benzoxadiazole as a water-soluble fluorogenic reagent for the sensitive liquid chromatographic determination of saturated carboxylic acids. The Analyst. 2002 Jun; 127(6):741-7. doi: 10.1039/b201023m. [PMID: 12146905]
  • I S Kim, Y I Jeong, D H Kim, Y H Lee, S H Kim. Albumin release from biodegradable hydrogels composed of dextran and poly(ethylene glycol) macromer. Archives of pharmacal research. 2001 Feb; 24(1):69-73. doi: 10.1007/bf02976496. [PMID: 11235815]
  • S Duewell, C E Kasserra, P Jezzard, R S Balaban. Evaluation of methemoglobin as an autologous intravascular MRI contrast agent. Magnetic resonance in medicine. 1996 May; 35(5):787-9. doi: 10.1002/mrm.1910350521. [PMID: 8722831]
  • H Salari, G K Eigendorf. Detection of lyso-platelet-activating factor by high-performance liquid chromatography after derivatisation with fluorescent fatty acids. Journal of chromatography. 1990 May; 527(2):303-14. doi: 10.1016/s0378-4347(00)82114-3. [PMID: 2387879]
  • J G Haddad, J Abrams, J Walgate. Affinity chromatography with 25-hydroxycholecalciferol ester in the isolation of the binding protein for vitamin D and its metabolites from human serum. Metabolic bone disease & related research. 1981; 3(1):43-6. doi: 10.1016/s0221-8747(81)80022-7. [PMID: 6894958]
  • V Fell, C R Lee. Determination of urinary monohydric and dihydric phenols by gas chromatography of the acetate and TMS derivatives. 4-Dimethylaminopyridine as a catalyst for acetylation reactions. Journal of chromatography. 1976 Jun; 121(1):41-7. doi: 10.1016/s0021-9673(00)82296-7. [PMID: 932134]