4-Aminobenzohydrazide (BioDeep_00000174329)
human metabolite blood metabolite Volatile Flavor Compounds
代谢物信息卡片
化学式: C7H9N3O (151.0745584)
中文名称: 4-氨基苯甲酰肼
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC(=CC=C1C(=O)NN)N
InChI: InChI=1S/C7H9N3O/c8-6-3-1-5(2-4-6)7(11)10-9/h1-4H,8-9H2,(H,10,11)
数据库引用编号
5 个数据库交叉引用编号
- PubChem: 21450
- HMDB: HMDB0246354
- ChEMBL: CHEMBL2170241
- chemspider: 20160
- CAS: 5351-17-7
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Danielba Almeida da Silva, Thiago Macêdo Lopes Correia, Rafael Pereira, Robson Amaro Augusto da Silva, Ohara Augusto, Raphael Ferreira Queiroz. Tempol reduces inflammation and oxidative damage in cigarette smoke-exposed mice by decreasing neutrophil infiltration and activating the Nrf2 pathway.
Chemico-biological interactions.
2020 Sep; 329(?):109210. doi:
10.1016/j.cbi.2020.109210
. [PMID: 32726580] - Kanta Pravalika, Deepaneeta Sarmah, Harpreet Kaur, Kanchan Vats, Jackson Saraf, Madhuri Wanve, Kiran Kalia, Anupom Borah, Dileep R Yavagal, Kunjan R Dave, Pallab Bhattacharya. Trigonelline therapy confers neuroprotection by reduced glutathione mediated myeloperoxidase expression in animal model of ischemic stroke.
Life sciences.
2019 Jan; 216(?):49-58. doi:
10.1016/j.lfs.2018.11.014
. [PMID: 30414429] - Sandeep Ramalingam, Baiyi Cai, Junsheng Wong, Matthew Twomey, Rui Chen, Rebecca M Fu, Toby Boote, Hugh McCaughan, Samantha J Griffiths, Jürgen G Haas. Antiviral innate immune response in non-myeloid cells is augmented by chloride ions via an increase in intracellular hypochlorous acid levels.
Scientific reports.
2018 09; 8(1):13630. doi:
10.1038/s41598-018-31936-y
. [PMID: 30206371] - Jiansheng Huang, Forrest Smith, Jennifer R Panizzi, Douglas C Goodwin, Peter Panizzi. Inactivation of myeloperoxidase by benzoic acid hydrazide.
Archives of biochemistry and biophysics.
2015 Mar; 570(?):14-22. doi:
10.1016/j.abb.2015.01.028
. [PMID: 25688920] - Luciana M Kabeya, Carolina N Fuzissaki, Silvia H Taleb-Contini, Ana Maria da C Ferreira, Zeki Naal, Everton O L Santos, Andréa S G Figueiredo-Rinhel, Ana Elisa C S Azzolini, Roberta B Vermelho, Alberto Malvezzi, Antonia T-do Amaral, João Luis C Lopes, Yara Maria Lucisano-Valim. 7-Hydroxycoumarin modulates the oxidative metabolism, degranulation and microbial killing of human neutrophils.
Chemico-biological interactions.
2013 Oct; 206(1):63-75. doi:
10.1016/j.cbi.2013.08.010
. [PMID: 23994743] - E V Mikhal'chik, N V Smolina, T C Astamirova, I V Gorudko, D V Grigor'eva, V A Ivanov, A V Sokolov, V A Kostevich, S N Cherenkevich, O M Panasenko. [Human serum albumin modified under oxidative/halogenative stress enhances luminol-dependent chemiluminescence of human neutrophils].
Biofizika.
2013 Jul; 58(4):681-9. doi:
NULL
. [PMID: 24455888] - Raphael F Queiroz, Alessandro K Jordão, Anna C Cunha, Vitor F Ferreira, Maísa R P L Brigagão, Alberto Malvezzi, Antonia T-do Amaral, Ohara Augusto. Nitroxides attenuate carrageenan-induced inflammation in rat paws by reducing neutrophil infiltration and the resulting myeloperoxidase-mediated damage.
Free radical biology & medicine.
2012 Nov; 53(10):1942-53. doi:
10.1016/j.freeradbiomed.2012.09.001
. [PMID: 22982597] - I V Gorudko, O S Cherkalina, A V Sokolov, M O Pulina, E T Zakharova, V B Vasil'ev, S N Cherenkevich, O M Panasenko. [New approaches to the measurement of the concentration and peroxidase activity of myeloperoxidase in human blood plasma].
Bioorganicheskaia khimiia.
2009 Sep; 35(5):629-39. doi:
10.1134/s1068162009050057
. [PMID: 19915640] - Brett A Wagner, Lynn M Teesch, Garry R Buettner, Bradley E Britigan, C Patrick Burns, Krzysztof J Reszka. Inactivation of anthracyclines by serum heme proteins.
Chemical research in toxicology.
2007 Jun; 20(6):920-6. doi:
10.1021/tx700002f
. [PMID: 17497896] - Gábor Békési, Helmut Heinle, Réka Kakucs, Tamás Pázmány, Dezso Szombath, Mariann Dinya, Zsolt Tulassay, János Fehér, Károly Rácz, Béla Székács, Eva Riss, Andrea Farkas, Ferenc Gódor, György Illyés. Effect of inhibitors of myeloperoxidase on the development of aortic atherosclerosis in an animal model.
Experimental gerontology.
2005 Mar; 40(3):199-208. doi:
10.1016/j.exger.2004.12.004
. [PMID: 15763397] - Stefanie Heigold, Georg Bauer. RAW 264.7 macrophages induce apoptosis selectively in transformed fibroblasts: intercellular signaling based on reactive oxygen and nitrogen species.
Journal of leukocyte biology.
2002 Sep; 72(3):554-63. doi:
NULL
. [PMID: 12223524] - G Békési, R Kakucs, J Sándor, E Sárváry, I Kocsis, D Sprintz, S Várbíró, Z Magyar, A Hrabák, J Fehér, B Székács. Plasma concentration of myeloperoxidase enzyme in pre- and post-climacterial people: related superoxide anion generation.
Experimental gerontology.
2001 Dec; 37(1):137-48. doi:
10.1016/s0531-5565(01)00151-6
. [PMID: 11738154] - G O Peelen, J G de Jong, R A Wevers. High-performance liquid chromatography of monosaccharides and oligosaccharides in a complex biological matrix.
Analytical biochemistry.
1991 Nov; 198(2):334-41. doi:
10.1016/0003-2697(91)90435-v
. [PMID: 1799219]