4-Acetylaminohippuric acid (BioDeep_00000174308)

   

human metabolite blood metabolite


代谢物信息卡片


2-[(4-acetamidophenyl)formamido]acetic acid

化学式: C11H12N2O4 (236.07970319999998)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(blood) 50%

分子结构信息

SMILES: CC(=O)NC1=CC=C(C=C1)C(=O)NCC(=O)O
InChI: InChI=1S/C11H12N2O4/c1-7(14)13-9-4-2-8(3-5-9)11(17)12-6-10(15)16/h2-5H,6H2,1H3,(H,12,17)(H,13,14)(H,15,16)



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Lai-Hao Wang, Wen-Shiuan Huang, Huo-Mu Tai. Simultaneous determination of p-aminobenzoic acid and its metabolites in the urine of volunteers, treated with p-aminobenzoic acid sunscreen formulation. Journal of pharmaceutical and biomedical analysis. 2007 Mar; 43(4):1430-6. doi: 10.1016/j.jpba.2006.10.021. [PMID: 17118613]
  • Don Farthing, Domenic A Sica, Itaf Fakhry, Terri Larus, Sid Ghosh, Christine Farthing, Michael Vranian, Todd Gehr. Simple HPLC-UV method for determination of iohexol, iothalamate, p-aminohippuric acid and n-acetyl-p-aminohippuric acid in human plasma and urine with ERPF, GFR and ERPF/GFR ratio determination using colorimetric analysis. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2005 Nov; 826(1-2):267-72. doi: 10.1016/j.jchromb.2005.05.050. [PMID: 16169291]
  • Sylvie Lebel, Yoshiko Nakamachi, Alan Hemming, Zul Verjee, M James Phillips, Katryn N Furuya. Glycine conjugation of para-aminobenzoic acid (PABA): a pilot study of a novel prognostic test in acute liver failure in children. Journal of pediatric gastroenterology and nutrition. 2003 Jan; 36(1):62-71. doi: 10.1097/00005176-200301000-00013. [PMID: 12499998]
  • Y Sun, B Liu, J Wan, H Xu. [Quantitative assay of metabolic rate of para-aminobenzoic acid combining glycine for the assessment of rabbit liver function]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology. 2001 Aug; 9(4):240-1. doi: NULL. [PMID: 11602060]
  • T C Dowling, R F Frye, D S Fraley, G R Matzke. Characterization of tubular functional capacity in humans using para-aminohippurate and famotidine. Kidney international. 2001 Jan; 59(1):295-303. doi: 10.1046/j.1523-1755.2001.00491.x. [PMID: 11135083]
  • T C Dowling, R F Frye, M A Zemaitis. Simultaneous determination of p-aminohippuric acid, acetyl-p-aminohippuric acid and iothalamate in human plasma and urine by high-performance liquid chromatography. Journal of chromatography. B, Biomedical sciences and applications. 1998 Sep; 716(1-2):305-13. doi: 10.1016/s0378-4347(98)00294-1. [PMID: 9824245]
  • L A Decosterd, N Bélaz, M Appenzeller, A Maghraoui, P Rousso, T Buclin, J Biollaz. Specific determination of PAH and its N-acetyl metabolite by HPLC increases the accuracy and precision of PAH clearance measurements. Renal failure. 1998 Mar; 20(2):311-7. doi: 10.3109/08860229809045116. [PMID: 9574457]
  • K N Furuya, P R Durie, E A Roberts, S J Soldin, Z Verjee, L Yung-Jato, E Giesbrecht, L Ellis. Glycine conjugation of para-aminobenzoic acid (PABA): a quantitative test of liver function. Clinical biochemistry. 1995 Oct; 28(5):531-40. doi: 10.1016/0009-9120(95)00040-g. [PMID: 8582053]
  • R Kastel, I Rosival, J Blahovec. Simultaneous determination of p-aminobenzoic acid and its metabolites in urine by high performance liquid chromatography. Biomedical chromatography : BMC. 1994 Nov; 8(6):294-6. doi: 10.1002/bmc.1130080609. [PMID: 7888733]
  • C L Wabner, T S Chen. Aging changes in renal handling of p-aminohippurate. The American journal of physiology. 1987 May; 252(5 Pt 2):R871-7. doi: 10.1152/ajpregu.1987.252.5.r871. [PMID: 3578554]
  • L M Stolk, L S Chandi-Bakridi, J C Filedt Kok, M G Koopman, F M Zuyderhoudt, L Arisz. Formulation of a stable p-acetylaminohippurate infusion fluid and determination of the serum concentrations. Pharmaceutisch weekblad. Scientific edition. 1985 Aug; 7(4):146-9. doi: 10.1007/bf02097251. [PMID: 4047913]