4-Acetamidobenzoic acid (BioDeep_00000174305)
human metabolite blood metabolite
代谢物信息卡片
化学式: C9H9NO3 (179.05824040000002)
中文名称: 4-乙酰氨基苯甲酸
谱图信息:
最多检出来源 Homo sapiens(blood) 15.38%
分子结构信息
SMILES: c1(ccc(cc1)C(=O)O)NC(=O)C
InChI: InChI=1S/C9H9NO3/c1-6(11)10-8-4-2-7(3-5-8)9(12)13/h2-5H,1H3,(H,10,11)(H,12,13)
描述信息
COVID info from PDB, Protein Data Bank
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
同义名列表
27 个代谢物同义名
4-Acetamidobenzoic acid, sodium salt; N-Acetyl-p-aminobenzoic acid; p-(Acetylamino)benzoic acid; 4-(Acetylamino)benzoic acid; PARA acetamido benzoIC ACID; Acetyl-p-aminobenzoic acid; Para-acetamidobenzoic acid; p-Acetylaminobenzoic acid; 4-Acetylaminobenzoic acid; p-Acetoaminobenzoic acid; N-Acetyl-p-aminobenzoate; 4-(Acetylamino)benzoate; PARA acetamido benzoate; p-Acetamidobenzoic acid; 4-Acetamidobenzoic acid; p-Acetylaminobenzoate; 4-Acetylaminobenzoate; 4-Carboxyacetanilide; p-Acetoaminobenzoate; 4-Acetamidobenzoate; p-Acetamidobenzoate; N-Acetyl-paba; Acedobenum; Fibroderm; Acedobene; Acedoben; PACBA
数据库引用编号
11 个数据库交叉引用编号
- ChEBI: CHEBI:46171
- PubChem: 19266
- HMDB: HMDB0246328
- DrugBank: DB04500
- ChEMBL: CHEMBL112687
- Wikipedia: Acedoben
- KNApSAcK: C00044987
- chemspider: 18177
- CAS: 556-08-1
- PMhub: MS000001281
- RefMet: 4-Acetamidobenzoic acid
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040
. [PMID: 33910017] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964
. [PMID: 31515284] - Ju-Ju Shang, Hui Shi, Qi Zhou, Wei Gao, Hong-Xu Liu. A Study of Prognosis, Outcome, and Changing Tendency of Hospitalized AMI Patients in Beijing Third-Grade A-Level Traditional Chinese Medicine Hospitals from 1999 to 2008.
Evidence-based complementary and alternative medicine : eCAM.
2012; 2012(?):837194. doi:
10.1155/2012/837194
. [PMID: 22536293] - Lai-Hao Wang, Wen-Shiuan Huang, Huo-Mu Tai. Simultaneous determination of p-aminobenzoic acid and its metabolites in the urine of volunteers, treated with p-aminobenzoic acid sunscreen formulation.
Journal of pharmaceutical and biomedical analysis.
2007 Mar; 43(4):1430-6. doi:
10.1016/j.jpba.2006.10.021
. [PMID: 17118613] - . Toxicology and carcinogenesis studies of p-nitrotoluene (CAS no. 99-99-0) in F344/N rats and B6C3F(1) mice (feed studies).
National Toxicology Program technical report series.
2002 May; ?(498):1-277. doi:
. [PMID: 12118261]
- Y Sun, B Liu, J Wan, H Xu. [Quantitative assay of metabolic rate of para-aminobenzoic acid combining glycine for the assessment of rabbit liver function].
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology.
2001 Aug; 9(4):240-1. doi:
NULL
. [PMID: 11602060] - A Szoke, W L Hayton, I R Schultz. Quantification of benzocaine and its metabolites in channel catfish tissues and fluids by HPLC.
Journal of pharmaceutical and biomedical analysis.
1997 Sep; 16(1):69-75. doi:
10.1016/s0731-7085(97)00014-9
. [PMID: 9447553] - K N Furuya, P R Durie, E A Roberts, S J Soldin, Z Verjee, L Yung-Jato, E Giesbrecht, L Ellis. Glycine conjugation of para-aminobenzoic acid (PABA): a quantitative test of liver function.
Clinical biochemistry.
1995 Oct; 28(5):531-40. doi:
10.1016/0009-9120(95)00040-g
. [PMID: 8582053] - F L Geoghegan, J M McPartlin, D G Weir, J M Scott. para-acetamidobenzoylglutamate is a suitable indicator of folate catabolism in rats.
The Journal of nutrition.
1995 Oct; 125(10):2563-70. doi:
10.1093/jn/125.10.2563
. [PMID: 7562091] - R Kastel, I Rosival, J Blahovec. Simultaneous determination of p-aminobenzoic acid and its metabolites in urine by high performance liquid chromatography.
Biomedical chromatography : BMC.
1994 Nov; 8(6):294-6. doi:
10.1002/bmc.1130080609
. [PMID: 7888733] - K Chan, J O Miners, D J Birkett. Direct and simultaneous high-performance liquid chromatographic assay for the determination of p-aminobenzoic acid and its conjugates in human urine.
Journal of chromatography.
1988 Apr; 426(1):103-9. doi:
10.1016/s0378-4347(00)81931-3
. [PMID: 3260239] - K Chan. High performance liquid chromatographic characterisation and quantitation of p-aminobenzoic acid N-acetylation in Chinese subjects.
European journal of drug metabolism and pharmacokinetics.
1986 Apr; 11(2):129-34. doi:
10.1007/bf03189838
. [PMID: 3490383] - H T Karnes, C M Riley, S H Curry, S G Schulman. Analysis of N-benzoyl-L-tyrosyl-p-aminobenzoic acid (bentiromide) metabolites in urine by ion-pair high-performance liquid chromatography.
Journal of chromatography.
1985 Mar; 338(2):377-88. doi:
10.1016/0378-4347(85)80108-0
. [PMID: 3873465] - D G Streeter, E H Pfadenhauer. Inosiplex: metabolism and excretion of the dimethylaminoisopropanol and p-acetamidobenzoic acid components in rhesus monkeys.
Drug metabolism and disposition: the biological fate of chemicals.
1984 Mar; 12(2):199-203. doi:
. [PMID: 6202473]
- A M Saleh, A E Pheasant, J A Blair, R N Allan, J Walters. Folate metabolism in man: the effect of malignant disease.
British journal of cancer.
1982 Sep; 46(3):346-53. doi:
10.1038/bjc.1982.210
. [PMID: 6982057] - E J Kuzniar, S P James. Influence of the gut microflora on the metabolism of 4-nitrobenzoic acid in the marmoset.
Xenobiotica; the fate of foreign compounds in biological systems.
1981 Oct; 11(10):675-83. doi:
10.3109/00498258109049087
. [PMID: 6976659] - J C Libeer, S L Scharpé, R M Verkerk, A J Deprettere, P J Schepens. Simultaneous determination of p-aminobenzoic acid, acetyl-p-aminobenzoic acid and p-aminohippuric acid in serum and urine by capillary gas chromatography with use of a nitrogen-phosphorus detector.
Clinica chimica acta; international journal of clinical chemistry.
1981 Sep; 115(2):119-23. doi:
10.1016/0009-8981(81)90067-x
. [PMID: 6974621] - A C Buck. Disorders of micturition in bacterial prostatitis.
Proceedings of the Royal Society of Medicine.
1975 Aug; 68(8):508-11. doi:
NULL
. [PMID: 681]