4-Acetamidobenzenesulfonamide (BioDeep_00000174304)

   

human metabolite blood metabolite


代谢物信息卡片


Sulfacetamide, monosodium salt, anhydrous

化学式: C8H10N2O3S (214.041211)
中文名称: 4-乙酰氨基苯磺酰胺
谱图信息: 最多检出来源 Homo sapiens(blood) 60%

分子结构信息

SMILES: CC(=O)NC1=CC=C(C=C1)S(=O)(=O)N
InChI: InChI=1S/C8H10N2O3S/c1-6(11)10-7-2-4-8(5-3-7)14(9,12)13/h2-5H,1H3,(H,10,11)(H2,9,12,13)

描述信息

D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents
D000890 - Anti-Infective Agents > D013424 - Sulfanilamides

同义名列表

35 个代谢物同义名

Sulfacetamide, monosodium salt, anhydrous; N-(4-sulfamoylphenyl)ethanimidic acid; N-(4-Sulphamoylphenyl)acetamide; 4-Acetamidobenzenesulphonamide; Monosodium salt, sulfacetamide; 4-Acetamidobenzenesulfonamide; Sulfacetamide monosodium salt; Sulfacetam, coliriocilina; Coliriocilina sulfacetam; Sulfacetamida, colircusi; Colircusi sulfacetamida; Sodium, sulfacetamide; N4-Acetyl metabolite; Sulfacetamide sodium; Acetylsulfanilamide; Isopto cetamide; Sulamyd, sodium; Sulphacetamide; Sodium sulamyd; sulfacetamide; Ceta sulfa; Belph-10; Belph 10; Sulfacil; Sulfacyl; cetamide; Sulf-10; AK sulf; AK-sulf; Acetopt; Sulfair; Albucid; Sulf 10; Antébor; Bleph



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Nishikant Wase, Boqiang Tu, James W Allen, Paul N Black, Concetta C DiRusso. Identification and Metabolite Profiling of Chemical Activators of Lipid Accumulation in Green Algae. Plant physiology. 2017 Aug; 174(4):2146-2165. doi: 10.1104/pp.17.00433. [PMID: 28652262]
  • Dan-Dan Zhang, Xin-Yan Wang, Jie-Yin Chen, Zhi-Qiang Kong, Yue-Jing Gui, Nan-Yang Li, Yu-Ming Bao, Xiao-Feng Dai. Identification and characterization of a pathogenicity-related gene VdCYP1 from Verticillium dahliae. Scientific reports. 2016 06; 6(?):27979. doi: 10.1038/srep27979. [PMID: 27329129]
  • A P Solomenny, Ya E Lyapunov, R Z Kuzyaev. Genetic variability of enterobacterial resistant integrons. Bulletin of experimental biology and medicine. 2011 Sep; 151(5):619-21. doi: 10.1007/s10517-011-1397-6. [PMID: 22462060]
  • Praveen N Naik, Shivamurti A Chimatadar, Sharanappa T Nandibewoor. Pharmacokinetic study on the mechanism of interaction of sulfacetamide sodium with bovine serum albumin: a spectroscopic method. Biopharmaceutics & drug disposition. 2010 Mar; 31(2-3):120-8. doi: 10.1002/bdd.696. [PMID: 20073032]
  • C A Spinks, G M Wyatt, H A Lee, M R Morgan. Molecular modeling of hapten structure and relevance to broad specificity immunoassay of sulfonamide antibiotics. Bioconjugate chemistry. 1999 Jul; 10(4):583-8. doi: 10.1021/bc980054m. [PMID: 10411455]
  • L D Lashev, D A Pashov. Interspecies variations in plasma half-life of ampicillin, amoxycillin, sulphadimidine and sulphacetamide related to variations in body mass. Research in veterinary science. 1992 Sep; 53(2):160-4. doi: 10.1016/0034-5288(92)90104-a. [PMID: 1439204]
  • P K Khosla, V I Neeraj, S K Gupta, G Satpathy. Berberine, a potential drug for trachoma. Revue internationale du trachome et de pathologie oculaire tropicale et subtropicale et de sante publique : organe de la Ligue contre le trachome avec la collaboration de l'International Organization against Trachoma et des organisation.... 1992; 69(?):147-65. doi: NULL. [PMID: 1344968]
  • P M Keagy, S M Oace. Rat bioassay of wheat bran folate and effects of intestinal bacteria. The Journal of nutrition. 1989 Dec; 119(12):1932-9. doi: 10.1093/jn/119.12.1932. [PMID: 2559958]
  • B P Vogh, D R Godman, T H Maren. Measurement of aqueous humor flow following scleral injection of sulfacetamide as marker: effect of methazolamide, timolol, and pilocarpine. Journal of ocular pharmacology. 1989; 5(4):293-302. doi: 10.1089/jop.1989.5.293. [PMID: 2628504]
  • F N Riabchuk, L M Lavut. [The activity of acetylation processes and the lipid metabolic indices of young infants with hypotrophy]. Pediatriia. 1988; ?(3):24-7. doi: ". [PMID: 3380612]
  • S Erill, P du Souich, H Courteau. Carbamylation of proteins and sulfacetamide free fraction in serum in experimentally-induced high blood urea states. Research communications in chemical pathology and pharmacology. 1985 Oct; 50(1):45-56. doi: NULL. [PMID: 4081313]
  • C R Fricker, R W Girdwood. The effect of the use of different selective media on the ability to recover salmonellae from seagull faeces. The Journal of hygiene. 1984 Aug; 93(1):35-42. doi: 10.1017/s0022172400060903. [PMID: 6747284]
  • V M Mahajan. Antimycotic activity of different chemicals, chaksine iodide and garlic. Mykosen. 1983 Feb; 26(2):94-9. doi: . [PMID: 6835269]
  • V V Dunaev, A V Karpenko. [Sodium sulfacil permeability across membrane structures of various degrees of organization as affected by a low-frequency magnetic field]. Farmakologiia i toksikologiia. 1983 Jan; 46(1):62-5. doi: NULL. [PMID: 6825822]
  • J Scruggs, T Wallace, C Hanna. Route of absorption of drug and ointment after application to the eye. Annals of ophthalmology. 1978 Mar; 10(3):267-71. doi: NULL. [PMID: 655537]
  • C Marchand, D Nadeau. The distribution and kinetics of sulphacetamide in leukaemic mice. British journal of pharmacology. 1976 Apr; 56(4):423-9. doi: 10.1111/j.1476-5381.1976.tb07453.x. [PMID: 1260222]
  • D Nadeau, C Marchand. Change in the kinetics of sulphacetamide tissue distribution in Walker tumor-bearing rats. Drug metabolism and disposition: the biological fate of chemicals. 1975 Nov; 3(6):565-76. doi: NULL. [PMID: 1234]
  • V Boniuk. An unusual case of blepharoptosis. Annals of ophthalmology. 1974 Apr; 6(4):373-4. doi: ". [PMID: 4595269]
  • A Grüneisen, H Witzgall. [Salivary excretion of sulphonamides. Correlation of drug levels in saliva and ultrafiltrate of plasma (author's transl)]. European journal of clinical pharmacology. 1974; 7(1):77-9. doi: 10.1007/bf00614395. [PMID: 4408105]
  • J H Perrin, D A Nelson. Competitive binding of two drugs for a single binding site on albumin: a circular dichroic study. The Journal of pharmacy and pharmacology. 1973 Feb; 25(2):125-30. doi: 10.1111/j.2042-7158.1973.tb10605.x. [PMID: 4146543]
  • C Marchand, D Nadeau. Effect of 2-diethylaminoethyl-2,2-diphenylvalerate hydrochloride (SKF 525-A) on sulphacetamide distribution and excretion in rats. British journal of pharmacology. 1973 Jan; 47(1):69-76. doi: 10.1111/j.1476-5381.1973.tb08159.x. [PMID: 4717021]
  • W Gerhardt, G Stein. [10 years of hemodialysis in Jena]. Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete. 1971 Feb; 26(3):116-9. doi: NULL. [PMID: 4934720]
  • H Zia, R H Cox, L A Luzzi. Competitive binding of two sulfas and penicillin G to bovine serum albumin using NMR techniques. Journal of pharmaceutical sciences. 1971 Jan; 60(1):45-7. doi: 10.1002/jps.2600600106. [PMID: 5548240]
  • G E Miller, C M Stowe. Influence of oxytocin on diffusion of sulfonamides from plasma into bovine milk. Journal of dairy science. 1967 Jun; 50(6):840-6. doi: 10.3168/jds.s0022-0302(67)87533-7. [PMID: 6034740]
  • H C Hollifield, J D Winefordner. A phosphorimetric investigation of several sulfonamide drugs: A rapid direct procedure for the determination of drug levels in pooled human serum with specific application to sulfadiazine, sulfamethazine, sulfamerazine and sulfacetamide. Analytica chimica acta. 1966 Nov; 36(3):352-9. doi: 10.1016/0003-2670(66)80062-4. [PMID: 5979104]
  • I M Dumkin. [The use of blood preserved by the mass dilution method in surgical practice]. Vestnik khirurgii imeni I. I. Grekova. 1966 Apr; 96(4):62-4. doi: NULL. [PMID: 5998648]
  • O Jardetzky, N G Wade-Jardetzky. On the mechanism of the binding of sulfonamides to bovine serum albumin. Molecular pharmacology. 1965 Nov; 1(3):214-30. doi: NULL. [PMID: 5842823]
  • H WITZGALL, H BOYENS. [THE IMPORTANCE OF BINDING TO ALBUMIN, BODY CELLS AND BACTERIA FOR PHARMACODYNAMICS AND EFFECT OF MEDICINAL SUBSTANCES]. Archives internationales de pharmacodynamie et de therapie. 1964 Apr; 148(?):511-35. doi: NULL. [PMID: 14181244]
  • H W MCINTOSH, M SERAGLIA, I UHLEMANN, R KORE. EFFECT OF ACETAZOLAMIDE AND TRIPLE SULFONAMIDE ON CITRATE AND CALCIUM EXCRETION. Canadian Medical Association journal. 1963 Dec; 89(?):1332-3. doi: NULL. [PMID: 14101455]
  • H G KNAUFF, A GEORGII, K MATZEN. [THE EFFECT OF CHOLINE PHOSPHOLIPIDS ON THE SPECTRUM OF FREE PLASMA AMINO ACIDS IN TOXIC LIVER DAMAGE]. Klinische Wochenschrift. 1963 Sep; 41(?):915-9. doi: 10.1007/bf01482725. [PMID: 14053410]