4-(4-Nitrobenzyl)pyridine (BioDeep_00000174271)

   

human metabolite blood metabolite


代谢物信息卡片


4-(4-Nitrobenzyl)pyridine monoperchlorate

化学式: C12H10N2O2 (214.07422400000002)
中文名称: 4-(4-硝基苄基)吡啶
谱图信息: 最多检出来源 Homo sapiens(blood) 50%

分子结构信息

SMILES: C1=CC(=CC=C1CC2=CC=NC=C2)[N+](=O)[O-]
InChI: InChI=1S/C12H10N2O2/c15-14(16)12-3-1-10(2-4-12)9-11-5-7-13-8-6-11/h1-8H,9H2

描述信息

D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D002863 - Chromogenic Compounds
D004396 - Coloring Agents

同义名列表

4 个代谢物同义名

4-(4-Nitrobenzyl)pyridine monoperchlorate; 4-[(4-nitrophenyl)methyl]pyridine; 4-(4-Nitrobenzyl)pyridine; 4-(p-Nitrobenzyl)pyridine



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Nishikant Wase, Boqiang Tu, James W Allen, Paul N Black, Concetta C DiRusso. Identification and Metabolite Profiling of Chemical Activators of Lipid Accumulation in Green Algae. Plant physiology. 2017 Aug; 174(4):2146-2165. doi: 10.1104/pp.17.00433. [PMID: 28652262]
  • Marcio Fronza, Evelyn Lamy, Stefan Günther, Berta Heinzmann, Stefan Laufer, Irmgard Merfort. Abietane diterpenes induce cytotoxic effects in human pancreatic cancer cell line MIA PaCa-2 through different modes of action. Phytochemistry. 2012 Jun; 78(?):107-19. doi: 10.1016/j.phytochem.2012.02.015. [PMID: 22436445]
  • Sasipawan Machana, Natthida Weerapreeyakul, Sahapat Barusrux, Apiyada Nonpunya, Bungorn Sripanidkulchai, Thaweesak Thitimetharoch. Cytotoxic and apoptotic effects of six herbal plants against the human hepatocarcinoma (HepG2) cell line. Chinese medicine. 2011 Oct; 6(1):39. doi: 10.1186/1749-8546-6-39. [PMID: 22041055]
  • A Namera, Y Utsumi, M Yashiki, M Ohtani, T Imamura, T Kojima. Direct colorimetric method for determination of organophosphates in human urine. Clinica chimica acta; international journal of clinical chemistry. 2000 Jan; 291(1):9-18. doi: 10.1016/s0009-8981(99)00189-8. [PMID: 10612713]
  • K Futagami, C Narazaki, Y Kataoka, H Shuto, R Oishi. Application of high-performance thin-layer chromatography for the detection of organophosphorus insecticides in human serum after acute poisoning. Journal of chromatography. B, Biomedical sciences and applications. 1997 Dec; 704(1-2):369-73. doi: 10.1016/s0378-4347(97)00476-3. [PMID: 9518173]
  • K K Chan, P S Hong, K Tutsch, D L Trump. Clinical pharmacokinetics of cyclophosphamide and metabolites with and without SR-2508. Cancer research. 1994 Dec; 54(24):6421-9. doi: . [PMID: 7987837]
  • L D Lewis, D L Fitzgerald, P Mohan, N Thatcher, P G Harper, H J Rogers. The pharmacokinetics of ifosfamide given as short and long intravenous infusions in cancer patients. British journal of clinical pharmacology. 1991 Jan; 31(1):77-82. doi: 10.1111/j.1365-2125.1991.tb03860.x. [PMID: 2015174]
  • R Sohr, G Schmeck, R Preiss, M Matthias. [Methodology of the colorimetric determination of alkylating cytostatics with 4-(4'-nitrobenzyl)pyridine (NBP) in plasma]. Die Pharmazie. 1982 Nov; 37(11):777-9. doi: NULL. [PMID: 7163361]
  • G Hesse, W Schulze, E Wachtel. [On the methodology of the determination of alkylating activities of nitrogen mustards with nitrobenzylpyridine (NBP) in biological material (author's transl)]. Die Pharmazie. 1981 Sep; 36(9):609-12. doi: NULL. [PMID: 7301901]
  • J L Skibba, F G Collins. Modification of the 4-(p-nitrobenzyl) pyridine assay for measurement of melphalan and mechlorethamine in plasma. Journal of pharmacological methods. 1980 Sep; 4(2):155-63. doi: 10.1016/0160-5402(80)90034-0. [PMID: 7453192]