4-(1,1-Dimethylhexyl)phenol (BioDeep_00000174258)
human metabolite blood metabolite
代谢物信息卡片
4-(2-methylheptan-2-yl)phenol
化学式: C14H22O (206.1670562)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCC(C)(C)C1=CC=C(C=C1)O
InChI: InChI=1S/C14H22O/c1-4-5-6-11-14(2,3)12-7-9-13(15)10-8-12/h7-10,15H,4-6,11H2,1-3H3
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
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Plant Reactome(0)
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1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Alexandros G Asimakopoulos, Nikolaos S Thomaidis, Michael A Koupparis. Recent trends in biomonitoring of bisphenol A, 4-t-octylphenol, and 4-nonylphenol.
Toxicology letters.
2012 Apr; 210(2):141-54. doi:
10.1016/j.toxlet.2011.07.032. [PMID: 21888958] - Muna S Nahar, Amr S Soliman, Justin A Colacino, Antonia M Calafat, Kristen Battige, Ahmed Hablas, Ibrahim A Seifeldin, Dana C Dolinoy, Laura S Rozek. Urinary bisphenol A concentrations in girls from rural and urban Egypt: a pilot study.
Environmental health : a global access science source.
2012 Apr; 11(?):20. doi:
10.1186/1476-069x-11-20. [PMID: 22472083] - Jessica W Nelson, Madeleine Kangsen Scammell, Elizabeth E Hatch, Thomas F Webster. Social disparities in exposures to bisphenol A and polyfluoroalkyl chemicals: a cross-sectional study within NHANES 2003-2006.
Environmental health : a global access science source.
2012 Mar; 11(?):10. doi:
10.1186/1476-069x-11-10. [PMID: 22394520] - Stephen J Genuis, Sanjay Beesoon, Detlef Birkholz, Rebecca A Lobo. Human excretion of bisphenol A: blood, urine, and sweat (BUS) study.
Journal of environmental and public health.
2012; 2012(?):185731. doi:
10.1155/2012/185731. [PMID: 22253637] - Anoop Shankar, Srinivas Teppala. Urinary bisphenol A and hypertension in a multiethnic sample of US adults.
Journal of environmental and public health.
2012; 2012(?):481641. doi:
10.1155/2012/481641. [PMID: 22363351] - Xiaoyun Ye, Lee-Yang Wong, Amber M Bishop, Antonia M Calafat. Variability of urinary concentrations of bisphenol A in spot samples, first morning voids, and 24-hour collections.
Environmental health perspectives.
2011 Jul; 119(7):983-8. doi:
10.1289/ehp.1002701. [PMID: 21406337] - Li You, Xiangzhu Zhu, Martha J Shrubsole, Hong Fan, Jing Chen, Jie Dong, Chuan-Ming Hao, Qi Dai. Renal function, bisphenol A, and alkylphenols: results from the National Health and Nutrition Examination Survey (NHANES 2003-2006).
Environmental health perspectives.
2011 Apr; 119(4):527-33. doi:
10.1289/ehp.1002572. [PMID: 21147601] - J G Hengstler, H Foth, T Gebel, P-J Kramer, W Lilienblum, H Schweinfurth, W Völkel, K-M Wollin, U Gundert-Remy. Critical evaluation of key evidence on the human health hazards of exposure to bisphenol A.
Critical reviews in toxicology.
2011 Apr; 41(4):263-91. doi:
10.3109/10408444.2011.558487. [PMID: 21438738] - Monica K Silver, Marie S O'Neill, Maryfran R Sowers, Sung Kyun Park. Urinary bisphenol A and type-2 diabetes in U.S. adults: data from NHANES 2003-2008.
PloS one.
2011; 6(10):e26868. doi:
10.1371/journal.pone.0026868. [PMID: 22046388] - Sujuan Yan, Yamei Chen, Min Dong, Weizhong Song, Scott M Belcher, Hong-Sheng Wang. Bisphenol A and 17β-estradiol promote arrhythmia in the female heart via alteration of calcium handling.
PloS one.
2011; 6(9):e25455. doi:
10.1371/journal.pone.0025455. [PMID: 21980463] - David Cantonwine, John D Meeker, Howard Hu, Brisa N Sánchez, Héctor Lamadrid-Figueroa, Adriana Mercado-García, Gamola Z Fortenberry, Antonia M Calafat, Martha Maria Téllez-Rojo. Bisphenol a exposure in Mexico City and risk of prematurity: a pilot nested case control study.
Environmental health : a global access science source.
2010 Oct; 9(?):62. doi:
10.1186/1476-069x-9-62. [PMID: 20955576] - E Pitarch, T Portolés, J M Marín, M Ibáñez, F Albarrán, F Hernández. Analytical strategy based on the use of liquid chromatography and gas chromatography with triple-quadrupole and time-of-flight MS analyzers for investigating organic contaminants in wastewater.
Analytical and bioanalytical chemistry.
2010 Aug; 397(7):2763-76. doi:
10.1007/s00216-010-3692-x. [PMID: 20428853] - Neelakanteswar Aluru, John F Leatherland, Mathilakath M Vijayan. Bisphenol A in oocytes leads to growth suppression and altered stress performance in juvenile rainbow trout.
PloS one.
2010 May; 5(5):e10741. doi:
10.1371/journal.pone.0010741. [PMID: 20505776] - David Melzer, Neil E Rice, Ceri Lewis, William E Henley, Tamara S Galloway. Association of urinary bisphenol a concentration with heart disease: evidence from NHANES 2003/06.
PloS one.
2010 Jan; 5(1):e8673. doi:
10.1371/journal.pone.0008673. [PMID: 20084273] - Joe M Braun, Kimberly Yolton, Kim N Dietrich, Richard Hornung, Xiaoyun Ye, Antonia M Calafat, Bruce P Lanphear. Prenatal bisphenol A exposure and early childhood behavior.
Environmental health perspectives.
2009 Dec; 117(12):1945-52. doi:
10.1289/ehp.0900979. [PMID: 20049216] - Antonia M Calafat, Jennifer Weuve, Xiaoyun Ye, Lily T Jia, Howard Hu, Steven Ringer, Ken Huttner, Russ Hauser. Exposure to bisphenol A and other phenols in neonatal intensive care unit premature infants.
Environmental health perspectives.
2009 Apr; 117(4):639-44. doi:
10.1289/ehp.0800265. [PMID: 19440505] - Antonia M Calafat, Xiaoyun Ye, Lee-Yang Wong, John A Reidy, Larry L Needham. Exposure of the U.S. population to bisphenol A and 4-tertiary-octylphenol: 2003-2004.
Environmental health perspectives.
2008 Jan; 116(1):39-44. doi:
10.1289/ehp.10753. [PMID: 18197297] - Eun-Joung Ko, Kyoung-Woong Kim, Seo-Young Kang, Sang-Don Kim, Sun-Baek Bang, Se-Yeong Hamm, Dong-Wook Kim. Monitoring of environmental phenolic endocrine disrupting compounds in treatment effluents and river waters, Korea.
Talanta.
2007 Oct; 73(4):674-83. doi:
10.1016/j.talanta.2007.04.033. [PMID: 19073088] - Travis J Bistodeau, Larry B Barber, Stephen E Bartell, Roberto A Cediel, Kent J Grove, Jacob Klaustermeier, Janet C Woodard, Kathy E Lee, Heiko L Schoenfuss. Larval exposure to environmentally relevant mixtures of alkylphenolethoxylates reduces reproductive competence in male fathead minnows.
Aquatic toxicology (Amsterdam, Netherlands).
2006 Sep; 79(3):268-77. doi:
10.1016/j.aquatox.2006.06.015. [PMID: 16891002] - Masayoshi Ohshima, Shuji Ohno, Shizuo Nakajin. Inhibitory effects of some possible endocrine-disrupting chemicals on the isozymes of human 11beta-hydroxysteroid dehydrogenase and expression of their mRNA in gonads and adrenal glands.
Environmental sciences : an international journal of environmental physiology and toxicology.
2005; 12(4):219-30. doi:
. [PMID: 16184081] - K-E Tollefsen, J Ovrevik, J Stenersen. Binding of xenoestrogens to the sex steroid-binding protein in plasma from Arctic charr (Salvelinus alpinus L.).
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.
2004 Oct; 139(1-3):127-33. doi:
10.1016/j.cca.2004.10.003. [PMID: 15556074] - S Jobling, D Casey, T Rogers-Gray, J Oehlmann, U Schulte-Oehlmann, S Pawlowski, T Baunbeck, A P Turner, C R Tyler. Comparative responses of molluscs and fish to environmental estrogens and an estrogenic effluent.
Aquatic toxicology (Amsterdam, Netherlands).
2004 Feb; 66(2):207-22. doi:
10.1016/j.aquatox.2004.01.002. [PMID: 15046010] - Stephen H Safe, Lea Pallaroni, Kyungsil Yoon, Kevin Gaido, Susan Ross, Donald McDonnell. Problems for risk assessment of endocrine-active estrogenic compounds.
Environmental health perspectives.
2002 Dec; 110 Suppl 6(?):925-9. doi:
10.1289/ehp.02110s6925. [PMID: 12634121] - Ramon Espejo, Karel Valter, Marco Simona, Yves Janin, Phillipe Arrizabalaga. Determination of nineteen 4-alkylphenol endocrine disrupters in Geneva municipal sewage wastewater.
Journal of chromatography. A.
2002 Nov; 976(1-2):335-43. doi:
10.1016/s0021-9673(02)01229-3. [PMID: 12462626] - Midori Yoshida, Shin-ichi Katsuda, Tomo Tanimoto, Sayaka Asai, Dai Nakae, Yuji Kurokawa, Kazuyoshi Taya, Akihiko Maekawa. Induction of different types of uterine adenocarcinomas in Donryu rats due to neonatal exposure to high-dose p-t-octylphenol for different periods.
Carcinogenesis.
2002 Oct; 23(10):1745-50. doi:
10.1093/carcin/23.10.1745. [PMID: 12376485] - K-E Tollefsen. Interaction of estrogen mimics, singly and in combination, with plasma sex steroid-binding proteins in rainbow trout (Oncorhynchus mykiss).
Aquatic toxicology (Amsterdam, Netherlands).
2002 Feb; 56(3):215-25. doi:
10.1016/s0166-445x(01)00154-0. [PMID: 11792437] - Takahito Nishiyama, Kenichiro Ogura, Hiroaki Nakano, Teppei Kaku, Eriko Takahashi, Yasunari Ohkubo, Koji Sekine, Akira Hiratsuka, Shigetoshi Kadota, Tadashi Watabe. Sulfation of environmental estrogens by cytosolic human sulfotransferases.
Drug metabolism and pharmacokinetics.
2002; 17(3):221-8. doi:
10.2133/dmpk.17.221. [PMID: 15618673] - K Van den Belt, R Verheyen, H Witters. Reproductive effects of ethynylestradiol and 4t-octylphenol on the zebrafish (Danio rerio).
Archives of environmental contamination and toxicology.
2001 Nov; 41(4):458-67. doi:
10.1007/s002440010272. [PMID: 11598783] - S H Safe, L Pallaroni, K Yoon, K Gaido, S Ross, B Saville, D McDonnellc. Toxicology of environmental estrogens.
Reproduction, fertility, and development.
2001; 13(4):307-15. doi:
10.1071/rd00108. [PMID: 11800169]