5,5-Dimethyl-1-pyrroline N-oxide (BioDeep_00000174158)

   

human metabolite blood metabolite


代谢物信息卡片


2,2-dimethyl-3,4-dihydro-2H-pyrrol-1-ium-1-olate

化学式: C6H11NO (113.0840596)
中文名称: 5,5-二甲基-1-吡咯啉-N-氧化物
谱图信息: 最多检出来源 Homo sapiens(blood) 94.12%

分子结构信息

SMILES: CC1(C)CCC=[N+]1[O-]
InChI: InChI=1S/C6H11NO/c1-6(2)4-3-5-7(6)8/h5H,3-4H2,1-2H3



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Shoko Okazaki, Ayako Hirata, Yusuke Shogomori, Megumi Takemoto, Takuro Nagata, Eriko Hayashida, Keizo Takeshita. Radical reactions induced by ketoprofen in phospholipid membranes under ultraviolet light irradiation. Journal of photochemistry and photobiology. B, Biology. 2021 Jan; 214(?):112090. doi: 10.1016/j.jphotobiol.2020.112090. [PMID: 33302245]
  • Xiaoxiao Feng, Yufei Hua, Caimeng Zhang, Xiangzhen Kong, Xingfei Li, Yeming Chen. Effect of soaking conditions on the formation of lipid derived free radicals in soymilk. Food chemistry. 2020 Jun; 315(?):126237. doi: 10.1016/j.foodchem.2020.126237. [PMID: 32014666]
  • Yasumasa Okazaki, Hiromasa Tanaka, Masaru Hori, Shinya Toyokuni. l-Dehydroascorbic acid recycled by thiols efficiently scavenges non-thermal plasma-induced hydroxyl radicals. Archives of biochemistry and biophysics. 2019 07; 669(?):87-95. doi: 10.1016/j.abb.2019.05.019. [PMID: 31153952]
  • Keita Saito, Deepak Sail, Kazutoshi Yamamoto, Shingo Matsumoto, Burchelle Blackman, Shun Kishimoto, Jeffrey R Brender, Rolf E Swenson, James B Mitchell, Murali C Krishna. Synthesis and evaluation of 13C-labeled 5-5-dimethyl-1-pyrroline-N-oxide aimed at in vivo detection of reactive oxygen species using hyperpolarized 13C-MRI. Free radical biology & medicine. 2019 02; 131(?):18-26. doi: 10.1016/j.freeradbiomed.2018.11.013. [PMID: 30471347]
  • Stephanie Albrecht, Anja Elpelt, Ceyda Kasim, Carina Reble, Lars Mundhenk, Hannah Pischon, Sarah Hedtrich, Christian Witzel, Jürgen Lademann, Leonhard Zastrow, Ingeborg Beckers, Martina C Meinke. Quantification and characterization of radical production in human, animal and 3D skin models during sun irradiation measured by EPR spectroscopy. Free radical biology & medicine. 2019 02; 131(?):299-308. doi: 10.1016/j.freeradbiomed.2018.12.022. [PMID: 30576782]
  • Patricia Coutinho de Souza, Nataliya Smith, Oluwatomisin Atolagbe, Jadith Ziegler, Charity Njoku, Megan Lerner, Marilyn Ehrenshaft, Ronald P Mason, Bill Meek, Scott M Plafker, Debra Saunders, Nadezda Mamedova, Rheal A Towner. OKN-007 decreases free radical levels in a preclinical F98 rat glioma model. Free radical biology & medicine. 2015 Oct; 87(?):157-68. doi: 10.1016/j.freeradbiomed.2015.06.026. [PMID: 26119786]
  • R A Towner, N Smith, D Saunders, J Carrizales, F Lupu, R Silasi-Mansat, M Ehrenshaft, R P Mason. In vivo targeted molecular magnetic resonance imaging of free radicals in diabetic cardiomyopathy within mice. Free radical research. 2015; 49(9):1140-6. doi: 10.3109/10715762.2015.1050587. [PMID: 25968951]
  • O I Pisarenko, V Z Lankin, G G Konovalova, L I Serebryakova, V S Shulzhenko, A A Timoshin, O V Tskitishvili, Yu A Pelogeykina, I M Studneva. Apelin-12 and its structural analog enhance antioxidant defense in experimental myocardial ischemia and reperfusion. Molecular and cellular biochemistry. 2014 Jun; 391(1-2):241-50. doi: 10.1007/s11010-014-2008-4. [PMID: 24599747]
  • Serdar Dogan, Gulsum Ozlem Elpek, Esma Kirimlioglu Konuk, Nejdet Demir, Mutay Aslan. Measurement of intracellular biomolecular oxidation in liver ischemia-reperfusion injury via immuno-spin trapping. Free radical biology & medicine. 2012 Aug; 53(3):406-14. doi: 10.1016/j.freeradbiomed.2012.05.028. [PMID: 22634144]
  • Rachel Haywood, Arsen Volkov, Carima Andrady, Robert Sayer. Measuring sunscreen protection against solar-simulated radiation-induced structural radical damage to skin using ESR/spin trapping: development of an ex vivo test method. Free radical research. 2012 Mar; 46(3):265-75. doi: 10.3109/10715762.2011.651719. [PMID: 22236285]
  • Ronit Lavi, Rinat Ankri, Michael Sinyakov, Maor Eichler, Harry Friedmann, Asher Shainberg, Haim Breitbart, Rachel Lubart. The plasma membrane is involved in the visible light-tissue interaction. Photomedicine and laser surgery. 2012 Jan; 30(1):14-9. doi: 10.1089/pho.2011.3083. [PMID: 21967485]
  • Mitsuuru Hata, Kyo Kobayashi, Fumihiko Yoshino, Ayaka Yoshida, Shuta Sugiyama, Chihiro Miyamoto, Fumiaki Tokutomi, Yojiro Maehata, Satoko Wada-Takahashi, Shun-Suke Takahashi, Tomoko Komatsu, Kazu-Ichi Yoshida, Masaichi-Chang-Il Lee. Direct assessment of the antioxidant properties of midazolam by electron spin resonance spectroscopy. Journal of anesthesia. 2011 Oct; 25(5):765-9. doi: 10.1007/s00540-011-1184-6. [PMID: 21688076]
  • Eva Hideg, Tamás Kálai, Kálmán Hideg. Direct detection of free radicals and reactive oxygen species in thylakoids. Methods in molecular biology (Clifton, N.J.). 2011; 684(?):187-200. doi: 10.1007/978-1-60761-925-3_16. [PMID: 20960131]
  • Ronit Lavi, Asher Shainberg, Vladimir Shneyvays, Elicheva Hochauser, Ahuva Isaac, Tova Zinman, Harry Friedmann, Rachel Lubart. Detailed analysis of reactive oxygen species induced by visible light in various cell types. Lasers in surgery and medicine. 2010 Aug; 42(6):473-80. doi: 10.1002/lsm.20919. [PMID: 20662023]
  • Kalina Ranguelova, Saurabh Chatterjee, Marilyn Ehrenshaft, Dario C Ramirez, Fiona A Summers, Maria B Kadiiska, Ronald P Mason. Protein Radical Formation Resulting from Eosinophil Peroxidase-catalyzed Oxidation of Sulfite. The Journal of biological chemistry. 2010 Jul; 285(31):24195-205. doi: 10.1074/jbc.m109.069054. [PMID: 20501663]
  • Kalina Ranguelova, Marcelo G Bonini, Ronald P Mason. (Bi)sulfite oxidation by copper, zinc-superoxide dismutase: Sulfite-derived, radical-initiated protein radical formation. Environmental health perspectives. 2010 Jul; 118(7):970-5. doi: 10.1289/ehp.0901533. [PMID: 20348042]
  • Totsapol Jirasomprasert, Noppawan P Morales, Lie M G Limenta, Srisuporn Sirijaroonwong, Paveena Yamanont, Prapin Wilairat, Suthat Fucharoen, Udom Chantharaksri. Pharmaco/ferrokinetic-related pro-oxidant activity of deferiprone in beta-thalassemia. Free radical research. 2009 May; 43(5):485-91. doi: 10.1080/10715760902870611. [PMID: 19353420]
  • Keita Saito, Masahiro Kohno, Fumihiko Yoshizaki, Yoshimi Niwano. Extensive screening for edible herbal extracts with potent scavenging activity against superoxide anions. Plant foods for human nutrition (Dordrecht, Netherlands). 2008 Jun; 63(2):65-70. doi: 10.1007/s11130-008-0071-2. [PMID: 18236159]
  • Sarah L Cuddihy, Amber Parker, D Tim Harwood, Margreet C M Vissers, Christine C Winterbourn. Ascorbate interacts with reduced glutathione to scavenge phenoxyl radicals in HL60 cells. Free radical biology & medicine. 2008 Apr; 44(8):1637-44. doi: 10.1016/j.freeradbiomed.2008.01.021. [PMID: 18291121]
  • J J Yin, Q Xia, P P Fu. UVA photoirradiation of anhydroretinol--formation of singlet oxygen and superoxide. Toxicology and industrial health. 2007 Nov; 23(10):625-31. doi: 10.1177/0748233708090909. [PMID: 18717521]
  • Cristina Rota, Lino Liverani, Franco Spelta, Giuseppe Mascellani, Aldo Tomasi, Anna Iannone, Elena Vismara. Free radical generation during chemical depolymerization of heparin. Analytical biochemistry. 2005 Sep; 344(2):193-203. doi: 10.1016/j.ab.2005.06.043. [PMID: 16098471]
  • Dario C Ramirez, Sandra E Gomez Mejiba, Ronald P Mason. Copper-catalyzed protein oxidation and its modulation by carbon dioxide: enhancement of protein radicals in cells. The Journal of biological chemistry. 2005 Jul; 280(29):27402-11. doi: 10.1074/jbc.m504241200. [PMID: 15905164]
  • Shin-ichi Ishikawa, Shizuna Ohtsuki, Kentarou Tomita, Keizo Arihara, Makoto Itoh. Protective effect of egg yolk phosvitin against ultraviolet- light-induced lipid peroxidation in the presence of iron ions. Biological trace element research. 2005; 105(1-3):249-56. doi: 10.1385/bter:105:1-3:249. [PMID: 16034168]
  • Junko Sajiki, Toshiki Masumizu. Inhibition of BPA degradation by serum as a hydroxyl radical scavenger and an Fe trapping agent in Fenton process. Chemosphere. 2004 Oct; 57(4):241-52. doi: 10.1016/j.chemosphere.2004.05.029. [PMID: 15312722]
  • Yasuhiro Kambayashi, Shozo Tero-Kubota, Yorihiro Yamamoto, Masashi Kato, Minoru Nakano, Kunio Yagi, Keiki Ogino. Formation of superoxide anion during ferrous ion-induced decomposition of linoleic acid hydroperoxide under aerobic conditions. Journal of biochemistry. 2003 Dec; 134(6):903-9. doi: 10.1093/jb/mvg217. [PMID: 14769880]
  • Clare M Jones, Mark J Burkitt. EPR spin-trapping evidence for the direct, one-electron reduction of tert-butylhydroperoxide to the tert-butoxyl radical by copper(II): paradigm for a previously overlooked reaction in the initiation of lipid peroxidation. Journal of the American Chemical Society. 2003 Jun; 125(23):6946-54. doi: 10.1021/ja034416z. [PMID: 12783547]
  • Reeko Sato, Osamu Inanami, Bunei Syuto, Jun Sato, Mikinori Kuwabara, Yoshihisa Naito. The plasma superoxide scavenging activity in canine cancer and hepatic disease. The Journal of veterinary medical science. 2003 Apr; 65(4):465-9. doi: 10.1292/jvms.65.465. [PMID: 12736428]
  • Akihiro Higuchi, Kosei Yonemitsu, Ako Koreeda, Shigeyuki Tsunenari. Inhibitory activity of epigallocatechin gallate (EGCg) in paraquat-induced microsomal lipid peroxidation--a mechanism of protective effects of EGCg against paraquat toxicity. Toxicology. 2003 Feb; 183(1-3):143-9. doi: 10.1016/s0300-483x(02)00512-7. [PMID: 12504348]
  • Stephen Nesnow, Barbara C Roop, Guy Lambert, Maria Kadiiska, Ronald P Mason, William R Cullen, Marc J Mass. DNA damage induced by methylated trivalent arsenicals is mediated by reactive oxygen species. Chemical research in toxicology. 2002 Dec; 15(12):1627-34. doi: 10.1021/tx025598y. [PMID: 12482246]
  • Takako Yokozawa, Yasuko Muto, Kunihiko Wakaki, Hiroshi Kashiwagi. Site of methylguanidine production and factors that influence production levels. Nephron. 2002 Oct; 92(2):356-62. doi: 10.1159/000063301. [PMID: 12218314]
  • P Green, S Glozman, L Weiner, E Yavin. Enhanced free radical scavenging and decreased lipid peroxidation in the rat fetal brain after treatment with ethyl docosahexaenoate. Biochimica et biophysica acta. 2001 Jun; 1532(3):203-12. doi: 10.1016/s1388-1981(01)00132-9. [PMID: 11470241]
  • H Zhang, J Joseph, J Feix, N Hogg, B Kalyanaraman. Nitration and oxidation of a hydrophobic tyrosine probe by peroxynitrite in membranes: comparison with nitration and oxidation of tyrosine by peroxynitrite in aqueous solution. Biochemistry. 2001 Jun; 40(25):7675-86. doi: 10.1021/bi002958c. [PMID: 11412121]
  • S I Dikalov, R P Mason. Spin trapping of polyunsaturated fatty acid-derived peroxyl radicals: reassignment to alkoxyl radical adducts. Free radical biology & medicine. 2001 Jan; 30(2):187-97. doi: 10.1016/s0891-5849(00)00456-1. [PMID: 11163536]
  • S Y Qian, H P Wang, F Q Schafer, G R Buettner. EPR detection of lipid-derived free radicals from PUFA, LDL, and cell oxidations. Free radical biology & medicine. 2000 Sep; 29(6):568-79. doi: 10.1016/s0891-5849(00)00407-x. [PMID: 11025200]
  • Y Noda, T Kneyuki, K Igarashi, A Mori, L Packer. Antioxidant activity of nasunin, an anthocyanin in eggplant peels. Toxicology. 2000 Aug; 148(2-3):119-23. doi: 10.1016/s0300-483x(00)00202-x. [PMID: 10962130]
  • C X Santos, E I Anjos, O Augusto. Uric acid oxidation by peroxynitrite: multiple reactions, free radical formation, and amplification of lipid oxidation. Archives of biochemistry and biophysics. 1999 Dec; 372(2):285-94. doi: 10.1006/abbi.1999.1491. [PMID: 10600166]
  • D Kristensen, L H Skibsted. Comparison of three methods based on electron spin resonance spectrometry for evaluation of oxidative stability of processed cheese. Journal of agricultural and food chemistry. 1999 Aug; 47(8):3099-104. doi: 10.1021/jf981396p. [PMID: 10552615]
  • N Matsuki, A Takanohashi, F M Boffi, O Inanami, M Kuwabara, K Ono. Hydroxyl radical generation and lipid peroxidation in C2C12 myotube treated with iodoacetate and cyanide. Free radical research. 1999 Jul; 31(1):1-8. doi: 10.1080/10715769900300551. [PMID: 10489115]
  • L J Hazell, M J Davies, R Stocker. Secondary radicals derived from chloramines of apolipoprotein B-100 contribute to HOCl-induced lipid peroxidation of low-density lipoproteins. The Biochemical journal. 1999 May; 339 ( Pt 3)(?):489-95. doi: 10.1042/bj3390489. [PMID: 10215584]
  • M Hermes-Lima, N C Santos, J Yan, M Andrews, H M Schulman, P Ponka. EPR spin trapping and 2-deoxyribose degradation studies of the effect of pyridoxal isonicotinoyl hydrazone (PIH) on *OH formation by the Fenton reaction. Biochimica et biophysica acta. 1999 Feb; 1426(3):475-82. doi: 10.1016/s0304-4165(98)00167-6. [PMID: 10076064]
  • P O'Brien, H J Salacinski. Evidence that the reactions of cadmium in the presence of metallothionein can produce hydroxyl radicals. Archives of toxicology. 1998 Nov; 72(11):690-700. doi: 10.1007/s002040050562. [PMID: 9879806]
  • P M Becker, S P Sanders, P Price, B W Christman. F2-isoprostane generation in isolated ferret lungs after oxidant injury or ventilated ischemia. Free radical biology & medicine. 1998 Oct; 25(6):703-11. doi: 10.1016/s0891-5849(98)00152-x. [PMID: 9801071]
  • D Gao, R Tawa, H Masaki, Y Okano, H Sakurai. Protective effects of baicalein against cell damage by reactive oxygen species. Chemical & pharmaceutical bulletin. 1998 Sep; 46(9):1383-7. doi: 10.1248/cpb.46.1383. [PMID: 9775434]
  • I Ueno, M Hoshino, T Miura, N Shinriki. Ozone exposure generates free radicals in the blood samples in vitro. Detection by the ESR spin-trapping technique. Free radical research. 1998 Aug; 29(2):127-35. doi: 10.1080/10715769800300141. [PMID: 9790514]
  • M Nose, T Koide, K Morikawa, M Inoue, Y Ogihara, Y Yabu, N Ohta. Formation of reactive oxygen intermediates might be involved in the trypanocidal activity of gallic acid. Biological & pharmaceutical bulletin. 1998 Jun; 21(6):583-7. doi: 10.1248/bpb.21.583. [PMID: 9657042]
  • U Rauen, H de Groot. Cold-induced release of reactive oxygen species as a decisive mediator of hypothermia injury to cultured liver cells. Free radical biology & medicine. 1998 May; 24(7-8):1316-23. doi: 10.1016/s0891-5849(97)00456-5. [PMID: 9626589]
  • S H Huang, S Leonard, X Shi, M R Goins, V Vallyathan. Antioxidant activity of lazaroid (U-75412E) and its protective effects against crystalline silica-induced cytotoxicity. Free radical biology & medicine. 1998 Mar; 24(4):529-36. doi: 10.1016/s0891-5849(97)00285-2. [PMID: 9559864]
  • W Adam, S Andler, C R Saha-Möller. DNA cleavage induced by oxyl radicals generated in the photosensitized decomposition of fatty ester hydroperoxides derived from oleic and linoleic acid. Archives of biochemistry and biophysics. 1998 Jan; 349(2):261-6. doi: 10.1006/abbi.1997.0353. [PMID: 9448713]
  • Z W Yang, F Y Yang. Sensitivity of Ca2+ transport of mitochondria to reactive oxygen species. Bioscience reports. 1997 Dec; 17(6):557-67. doi: 10.1023/a:1027316424985. [PMID: 9561301]
  • C Rota, D P Barr, M V Martin, F P Guengerich, A Tomasi, R P Mason. Detection of free radicals produced from the reaction of cytochrome P-450 with linoleic acid hydroperoxide. The Biochemical journal. 1997 Dec; 328 ( Pt 2)(?):565-71. doi: 10.1042/bj3280565. [PMID: 9371716]
  • X Shi, D C Flynn, D W Porter, S S Leonard, V Vallyathan, V Castranova. Efficacy of taurine based compounds as hydroxyl radical scavengers in silica induced peroxidation. Annals of clinical and laboratory science. 1997 Sep; 27(5):365-74. doi: ". [PMID: 9303176]
  • K Shimoi, B Shen, S Toyokuni, R Mochizuki, M Furugori, N Kinae. Protection by alpha G-rutin, a water-soluble antioxidant flavonoid, against renal damage in mice treated with ferric nitrilotriacetate. Japanese journal of cancer research : Gann. 1997 May; 88(5):453-60. doi: 10.1111/j.1349-7006.1997.tb00403.x. [PMID: 9247601]
  • U Rauen, B Elling, H de Groot. Injury to cultured liver endothelial cells after cold preservation: mediation by reactive oxygen species that are released independently of the known trigger hypoxia/reoxygenation. Free radical biology & medicine. 1997; 23(3):392-400. doi: 10.1016/s0891-5849(96)00618-1. [PMID: 9214575]
  • U Rauen, B Elling, E R Gizewski, H G Korth, R Sustmann, H de Groot. Involvement of reactive oxygen species in the preservation injury to cultured liver endothelial cells. Free radical biology & medicine. 1997; 22(1-2):17-24. doi: 10.1016/s0891-5849(96)00273-0. [PMID: 8958126]
  • F Beauseigneur, M Goubern, M F Chapey, J Gresti, C Vergely, M Tsoko, J Demarquoy, L Rochette, P Clouet. F1F0-ATPase, early target of the radical initiator 2,2'-azobis-(2-amidinopropane) dihydrochloride in rat liver mitochondria in vitro. The Biochemical journal. 1996 Dec; 320 ( Pt 2)(?):571-6. doi: 10.1042/bj3200571. [PMID: 8973568]
  • J B Schulz, D R Henshaw, U MacGarvey, M F Beal. Involvement of oxidative stress in 3-nitropropionic acid neurotoxicity. Neurochemistry international. 1996 Aug; 29(2):167-71. doi: 10.1016/0197-0186(95)00122-0. [PMID: 8837046]
  • M Kadkhodaee, G R Hanson, R A Towner, Z H Endre. Detection of hydroxyl and carbon-centred radicals by EPR spectroscopy after ischaemia and reperfusion of the rat kidney. Free radical research. 1996 Jul; 25(1):31-42. doi: 10.3109/10715769609145654. [PMID: 8814442]
  • T Yoshida, H Otake, Y Aramaki, T Hara, S Tsuchiya, A Hamada, H Utsumi. Free radicals from 1-palmitoyl-2-arachidonoylphosphatidylcholine liposomes in Fe2+/ascorbic acid solution. Biological & pharmaceutical bulletin. 1996 Jun; 19(6):779-82. doi: 10.1248/bpb.19.779. [PMID: 8799472]
  • K Hiramoto, N Ojima, K Sako, K Kikugawa. Effect of plant phenolics on the formation of the spin-adduct of hydroxyl radical and the DNA strand breaking by hydroxyl radical. Biological & pharmaceutical bulletin. 1996 Apr; 19(4):558-63. doi: 10.1248/bpb.19.558. [PMID: 8860958]
  • J Vásquez-Vivar, A M Santos, V B Junqueira, O Augusto. Peroxynitrite-mediated formation of free radicals in human plasma: EPR detection of ascorbyl, albumin-thiyl and uric acid-derived free radicals. The Biochemical journal. 1996 Mar; 314 ( Pt 3)(?):869-76. doi: 10.1042/bj3140869. [PMID: 8615782]
  • W Chamulitrat, N V Skrepnik, J J Spitzer. Endotoxin-induced oxidative stress in the rat small intestine: role of nitric oxide. Shock (Augusta, Ga.). 1996 Mar; 5(3):217-22. doi: 10.1097/00024382-199603000-00009. [PMID: 8696987]
  • C F Schaefer, E G Janzen, M S West, J L Poyer, S D Kosanke. Blood chemistry changes in the rat induced by high doses of nitronyl free radical spin traps. Free radical biology & medicine. 1996; 21(4):427-36. doi: 10.1016/0891-5849(96)00039-1. [PMID: 8886792]
  • D Zhang, T Yasuda, Y Yu, P Zheng, T Kawabata, Y Ma, S Okada. Ginseng extract scavenges hydroxyl radical and protects unsaturated fatty acids from decomposition caused by iron-mediated lipid peroxidation. Free radical biology & medicine. 1996; 20(1):145-50. doi: 10.1016/0891-5849(95)02020-9. [PMID: 8903691]
  • J Ueda, N Saito, T Ozawa. Detection of free radicals produced from reactions of lipid hydroperoxide model compounds with Cu(II) complexes by ESR spectroscopy. Archives of biochemistry and biophysics. 1996 Jan; 325(1):65-76. doi: 10.1006/abbi.1996.0008. [PMID: 8554344]
  • P O'Brien, H J Salacinski. Evidence for a relationship between the generation of reactive intermediates and the physicochemical characteristics of nickel oxides. Archives of toxicology. 1996; 70(12):787-800. doi: 10.1007/s002040050341. [PMID: 8911636]
  • T Ogino, S Okada. Oxidative damage of bovine serum albumin and other enzyme proteins by iron-chelate complexes. Biochimica et biophysica acta. 1995 Dec; 1245(3):359-65. doi: 10.1016/0304-4165(95)00101-8. [PMID: 8541312]
  • R Dunford, E J Land, M Rozanowska, T Sarna, T G Truscott. Interaction of melanin with carbon- and oxygen-centered radicals from methanol and ethanol. Free radical biology & medicine. 1995 Dec; 19(6):735-40. doi: 10.1016/0891-5849(95)00059-7. [PMID: 8582645]
  • G S Timmins, M J Davies, D X Song, U Muller-Eberhard. EPR studies on the effects of complexation of heme by hemopexin upon its reactions with organic peroxides. Free radical research. 1995 Dec; 23(6):559-69. doi: 10.3109/10715769509065277. [PMID: 8574350]
  • S Matsugo, L J Yan, D Han, H J Tritschler, L Packer. Elucidation of antioxidant activity of dihydrolipoic acid toward hydroxyl radical using a novel hydroxyl radical generator NP-III. Biochemistry and molecular biology international. 1995 Oct; 37(2):375-83. doi: . [PMID: 8673022]
  • Y Sato, S Kamo, T Takahashi, Y Suzuki. Mechanism of free radical-induced hemolysis of human erythrocytes: hemolysis by water-soluble radical initiator. Biochemistry. 1995 Jul; 34(28):8940-9. doi: 10.1021/bi00028a002. [PMID: 7619793]
  • Y Mao, L Zang, X Shi. Generation of free radicals by Cr(IV) from lipid hydroperoxides and its inhibition by chelators. Biochemistry and molecular biology international. 1995 Jun; 36(2):327-37. doi: ". [PMID: 7663436]
  • N V Gorbunov, A N Osipov, B W Day, B Zayas-Rivera, V E Kagan, N M Elsayed. Reduction of ferrylmyoglobin and ferrylhemoglobin by nitric oxide: a protective mechanism against ferryl hemoprotein-induced oxidations. Biochemistry. 1995 May; 34(20):6689-99. doi: 10.1021/bi00020a014. [PMID: 7756300]
  • S Gebicki, G Bartosz, J M Gebicki. The action of iron on amino acid and protein peroxides. Biochemical Society transactions. 1995 May; 23(2):249S. doi: 10.1042/bst023249s. [PMID: 7672272]
  • S Matsugo, L J Yan, D Han, H J Trischler, L Packer. Elucidation of antioxidant activity of alpha-lipoic acid toward hydroxyl radical. Biochemical and biophysical research communications. 1995 Mar; 208(1):161-7. doi: 10.1006/bbrc.1995.1318. [PMID: 7887924]
  • T Yokozawa, N Fujitsuka, H Oura, A Mori, H Kashiwagi. Determination of radical species in the kidney of rats with chronic renal failure by the spin trapping method. Nephron. 1995; 70(3):382-4. doi: 10.1159/000188627. [PMID: 7477636]
  • N S Dalal, J Newman, D Pack, S Leonard, V Vallyathan. Hydroxyl radical generation by coal mine dust: possible implication to coal workers' pneumoconiosis (CWP). Free radical biology & medicine. 1995 Jan; 18(1):11-20. doi: 10.1016/0891-5849(94)e0094-y. [PMID: 7896164]
  • V O'Donnell, M J Burkitt. Mitochondrial metabolism of a hydroperoxide to free radicals in human endothelial cells: an electron spin resonance spin-trapping investigation. The Biochemical journal. 1994 Dec; 304 ( Pt 3)(?):707-13. doi: 10.1042/bj3040707. [PMID: 7818471]
  • V Castranova. Generation of oxygen radicals and mechanisms of injury prevention. Environmental health perspectives. 1994 Dec; 102 Suppl 10(?):65-8. doi: 10.1289/ehp.94102s1065. [PMID: 7705309]
  • T M de Kok, D M Pachen, J M van Maanen, M V Lafleur, E J Westmijze, F ten Hoor, J C Kleinjans. Role of oxidative DNA damage in the mechanism of fecapentaene-12 genotoxicity. Carcinogenesis. 1994 Nov; 15(11):2559-65. doi: 10.1093/carcin/15.11.2559. [PMID: 7955106]
  • R M Gatti, R Radi, O Augusto. Peroxynitrite-mediated oxidation of albumin to the protein-thiyl free radical. FEBS letters. 1994 Jul; 348(3):287-90. doi: 10.1016/0014-5793(94)00625-3. [PMID: 8034056]
  • D J Kelman, J A DeGray, R P Mason. Reaction of myoglobin with hydrogen peroxide forms a peroxyl radical which oxidizes substrates. The Journal of biological chemistry. 1994 Mar; 269(10):7458-63. doi: . [PMID: 8125965]
  • Y M Kim, I Yamazaki, L H Piette. The effect of hemoglobin, hematin, and iron on neutrophil inactivation in superoxide generating systems. Archives of biochemistry and biophysics. 1994 Mar; 309(2):308-14. doi: 10.1006/abbi.1994.1118. [PMID: 8135543]
  • K Jankowski, D Kulawiak, M Woźniak. Inhibitory effect of 2-hydroxyestradiol on lipid peroxidation in placental microsomes. Acta biochimica Polonica. 1994; 41(2):151-2. doi: 10.18388/abp.1994_4742. [PMID: 7976029]
  • J D Adams, L K Klaidman, A C Leung. MPP+ and MPDP+ induced oxygen radical formation with mitochondrial enzymes. Free radical biology & medicine. 1993 Aug; 15(2):181-6. doi: 10.1016/0891-5849(93)90057-2. [PMID: 8397143]
  • T Takeuchi, K Morimoto, H Kosaka, T Shiga. Spin trapping of superoxide released by opsonized asbestos from human promyelocytic leukemia cell line, HL60. Biochemical and biophysical research communications. 1993 Jul; 194(1):57-64. doi: 10.1006/bbrc.1993.1784. [PMID: 8392845]
  • X Shi, N S Dalal, K S Kasprzak. Generation of free radicals from hydrogen peroxide and lipid hydroperoxides in the presence of Cr(III). Archives of biochemistry and biophysics. 1993 Apr; 302(1):294-9. doi: 10.1006/abbi.1993.1213. [PMID: 8385901]
  • S S Lloyd, A K Chang, F B Taylor, E G Janzen, P B McCay. Free radicals and septic shock in primates: the role of tumor necrosis factor. Free radical biology & medicine. 1993 Mar; 14(3):233-42. doi: 10.1016/0891-5849(93)90020-u. [PMID: 8384584]
  • K Yagi, S Komura, N Ishida, N Nagata, M Kohno, N Ohishi. Generation of hydroxyl radical from lipid hydroperoxides contained in oxidatively modified low-density lipoprotein. Biochemical and biophysical research communications. 1993 Jan; 190(2):386-90. doi: 10.1006/bbrc.1993.1059. [PMID: 8381274]
  • M J Davies, B C Gilbert, R M Haywood. Radical-induced damage to bovine serum albumin: role of the cysteine residue. Free radical research communications. 1993; 18(6):353-67. doi: 10.3109/10715769309147502. [PMID: 8397147]
  • H Masaki, T Atsumi, H Sakurai. Evaluation of superoxide scavenging activities of hamamelis extract and hamamelitannin. Free radical research communications. 1993; 19(5):333-40. doi: 10.3109/10715769309056522. [PMID: 8314114]
  • X Shi, N S Dalal, K S Kasprzak. Generation of free radicals from lipid hydroperoxides by Ni2+ in the presence of oligopeptides. Archives of biochemistry and biophysics. 1992 Nov; 299(1):154-62. doi: 10.1016/0003-9861(92)90257-w. [PMID: 1332613]
  • I Morel, J Cillard, G Lescoat, O Sergent, N Pasdeloup, A Z Ocaktan, M A Abdallah, P Brissot, P Cillard. Antioxidant and free radical scavenging activities of the iron chelators pyoverdin and hydroxypyrid-4-ones in iron-loaded hepatocyte cultures: comparison of their mechanism of protection with that of desferrioxamine. Free radical biology & medicine. 1992 Nov; 13(5):499-508. doi: 10.1016/0891-5849(92)90144-6. [PMID: 1334028]
  • M Tomita, T Okuyama, A Ueki, H Watanabe, S Kawai. Combined action of paraquat and superoxide on the peroxidation of detergent-dispersed linolenic acid. Biochimica et biophysica acta. 1992 Oct; 1128(2-3):174-80. doi: 10.1016/0005-2760(92)90304-e. [PMID: 1329974]
  • W Chamulitrat, H Iwahashi, D J Kelman, R P Mason. Evidence against the 1:2:2:1 quartet DMPO spectrum as the radical adduct of the lipid alkoxyl radical. Archives of biochemistry and biophysics. 1992 Aug; 296(2):645-9. doi: 10.1016/0003-9861(92)90621-3. [PMID: 1321592]
  • C M Julin, J J Zimmerman, V Sundaram, M C Chobanian. Activated neutrophils inhibit Na(+)-K(+)-ATPase in canine renal basolateral membrane. The American journal of physiology. 1992 Jun; 262(6 Pt 1):C1364-70. doi: 10.1152/ajpcell.1992.262.6.c1364. [PMID: 1319673]
  • J Taira, K Mimura, T Yoneya, A Hagi, A Murakami, K Makino. Hydroxyl radical formation by UV-irradiated epidermal cells. Journal of biochemistry. 1992 Jun; 111(6):693-5. doi: 10.1093/oxfordjournals.jbchem.a123820. [PMID: 1323559]
  • T L Greenley, M J Davies. Detection of radicals produced by reaction of hydroperoxides with rat liver microsomal fractions. Biochimica et biophysica acta. 1992 Apr; 1116(2):192-203. doi: 10.1016/0304-4165(92)90116-c. [PMID: 1316169]
  • N Cotelle, E Trémolières, J L Bernier, J P Catteau, J P Hénichart. Redox chemistry of complexes of nickel(II) with some biologically important peptides in the presence of reduced oxygen species: an ESR study. Journal of inorganic biochemistry. 1992 Apr; 46(1):7-15. doi: 10.1016/0162-0134(92)80058-4. [PMID: 1315842]